Cole Eye Institute - Cleveland Clinic

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Many serious sight-threatening disorders may affect only the surface of the eye, including the cornea. These conditions may disrupt or destroy the corneal
stem cells responsible for producing the eye’s healthy cellular surface. Cleveland Clinic surgeons have performed a number of stem cell transplants to
restore the ocular surface. In addition, they have created a device that facilitates harvesting the tissue from deceased donor tissue.
For patients with serious disorders who are not candidates for the more common types of corneal transplantation, the cornea may be replaced with an
artificial cornea, called a keratoprosthesis. Several of our patients
Intraoperative
have benefited
Complications
from this procedure, with excellent visual and anatomical results.
Intraoperative Complications
N = 223
0.4% Choroidal Hemorrhage
0.4% Corneal Graft Edema
99.2% None
A total of 205 keratoplasty procedures and 18 other corneal procedures with a total of 223 procedures were performed during the previously mentioned
period. The vast majority of patients have had successful clinical outcomes with no complications. Intraoperative complications occurred in only 0.9
percent of cases; they consisted of corneal graft edema and choroidal hemorrhage. The postoperative complication rate was 2.7 percent, with most
complications being retinal detachment, graft failure and persistent epithelial defect. The reoperation rate after corneal surgery (defined as a return to the
OR within 90 days) was 3.8 percent; this was due to failure of graft adhesion in DSAEK cases.
Analysis of intraoperative complications included all surgical procedures performed during this period. Analysis of postoperative complications and surgical
outcomes included those patients who had completed three months or more of follow-up. Consequently, the sample sizes reported for intraoperative and
postoperative complications differ.
Outcomes 2007 10