Managment of Herpes simplex Virus infection in pregnancy and in ...
Managment of Herpes simplex Virus infection in pregnancy and in ...
Managment of Herpes simplex Virus infection in pregnancy and in ...
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Risk <strong>of</strong> per<strong>in</strong>atal HSV transmission<br />
Seattle: 202 parturients with positive cultures, cultures,<br />
10 neonatal<br />
<strong><strong>in</strong>fection</strong>s<br />
% <strong>in</strong>fected OR (95% CI)<br />
• Infection episode<br />
– Reactivation (antibody ( antibody +) 1.3%<br />
– First episode (no ( no antibody) antibody 30.8% 33.1 (6.5-168)<br />
• HSV type<br />
– HSV-2 2.7%<br />
– HSV-1 31.3% 16.5 (4.1-65)<br />
• Mode <strong>of</strong> delivery<br />
– Vag<strong>in</strong>al 7.7%<br />
– Cesarean section 1.2% 0.14 (0.02-1.08)<br />
Brown ZR et al JAMA 2003; 289:203-9<br />
Ostschweizer K<strong>in</strong>derspital
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