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Sample Preparation Strategies for Water Analysis

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SPE of Acids and Base/Neutrals<br />

Mixed-Mode Mixed Mode Logic<br />

Consider:<br />

Aniline, phenol and benzyl alcohol on Mixed-Mode SPE<br />

NH 2 OH OH<br />

At pH 2 on Oasis ® MCX: Aniline is cation –retained<br />

Phenol is neutral – retained<br />

Benzyl alcohol is neutral – retained<br />

At pH 11 on Oasis ® MAX: Aniline is neutral – retained<br />

Phenol is anion – retained<br />

Benzyl alcohol is neutral – retained<br />

©2007 <strong>Water</strong>s Corporation 49

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