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Comparison of Stress and Learning Effects of Three Different ...

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HANS SELYE (1977), who is the pioneer <strong>of</strong> the studies on the biological mechanisms in the<br />

stress response, first used the term ‘’stress’’ for biological sciences, which had long been used<br />

in physical sciences, <strong>and</strong> named it ‘’biological stress’’. However, he later emphasized that<br />

what is called ‘’stress’’ in biology corresponds not to ‘’stress’’ but to ‘’strain’’ in physics.<br />

According to SELYE (1977), regardless <strong>of</strong> the characteristic <strong>of</strong> the stressor, the one<br />

nonspecific response-secretion <strong>of</strong> adrenal corticosteroids occurs. Therefore he changed the<br />

concept <strong>of</strong> ‘’stress’’ from a number <strong>of</strong> specific homeostatic responses to a nonspecific<br />

syndrome (FRIEND 1991).<br />

He also formulated a model called the ‘’General Adaptation Syndrome’’ (G.A.S) or<br />

‘’SELYE’s Syndrome’’, in which the hypophyseal-adrenal axis plays the central role. The<br />

syndrome develops in three consecutive stages: during the first stage called the ‘’alarm<br />

reaction’’, producing <strong>of</strong> high amount <strong>of</strong> ACTH results in considerable corticoid secretion.<br />

Under the condition <strong>of</strong> prolonged exposure to similar agents, a second stage called the ‘’stage<br />

<strong>of</strong> resistance’’ occurs. During this stage the organism adapts to the stressor <strong>and</strong> ‘’animals can<br />

meet dem<strong>and</strong>s with little increase in their basic ACTH <strong>and</strong> corticoid production’’ (SELYE<br />

1977). Finally, ‘’the stage <strong>of</strong> exhaustion’’ in which the adaptation energy <strong>and</strong> capability is lost<br />

sets in. SELYE (1977) also identified that under such circumstances several stress related<br />

diseases, which he called ‘’stress diseases’’ or ‘’diseases <strong>of</strong> adaptation’’ (such as<br />

gastrointestinal peptic ulcer, heart accidents, nervous exhaustion etc.) develop.<br />

Contrary to SELYE’s concept (1977) proposing that there is one non-specific response for all<br />

stressors, MASON (1968) showed that biological responses are stimulus-dependant, <strong>and</strong> that<br />

both ‘‘physical’’ <strong>and</strong> ‘’psychological’’ stimuli are capable <strong>of</strong> regulating adrenal cortical<br />

activity.<br />

MASON (1968) also emphasized that predictability; novelty <strong>and</strong> fear have great influence on<br />

adrenal cortex responses.<br />

BREAZILE (1987) defined ‘’stress’’ as an internal (physiologic or psychogenic) or<br />

environmental stimulus eliciting stress response or resulting in adaptation in an animal.<br />

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