NOVUS BIOLOGICALS ANTIBODIES FOR - BioNova

NOVUS BIOLOGICALS ANTIBODIES FOR 

NEUROSCIENCE

1 

Table of Contents 

G-Protein Coupled Receptors .. 2-6 

Signal Transduction .............. 7-8 

Epigenetic Regulation .........9-10 

Neurogenesis and 

Gliogenesis ....................11-12 

Axon Function and Structure ... 13 

Sensory Systems: 

Auditory & Olfactory .............. 14 

Sensory Systems: Vision ...15-16 

CNS Control of Metabolism .... 17 

Alzheimer’s Disease ............... 18 

Parkinson’s Disease .........19-20 

Huntington’s Disease ............. 21 

Multiple Sclerosis ................... 22 

Stroke, Epilepsy & Traumatic 

Brain Injury ............................ 22 

Neuronal Markers ...........23-24 

Antibody Support Products ...... 25 

Technical Support ................... 26 

Application Key 

ChIP - Chromatin Immunoprecipitation 

DB - Dot Blot 

ELISA - Enzyme-linked 

Immunosorbent Assay 

FACS - Fluorescent Activated Cell Sorting 

ICC - Immunocytochemistry 

IF - Immunofluorescence 

IHC - Immunohistochemistry 

IHC-Fr - Immunohistochemistry Frozen 

IHC-P - Immunohistochemistry Paraffin 

IP - Immunoprecipitation 

PEP-ELISA - Peptide Enzyme-linked 

Immunosorbent Assay 

RIA - Radioimmunoassay 

WB - Western Blot 

Reactivity Key 

Av - Avian 

Am - Amphibian 

Bv - Bovine 

Ca - Canine 

Ce - C. elegans 

Ch - Chicken 

Dr - Drosophila 

Fe - Feline 

Fi - Fish 

GP - Guinea Pig 

Hu - Human 

Le - Leech 

Ma - Mammal 

Mk - Monkey 

Mu - Mouse 

Po - Porcine 

Rb - Rabbit 

Rt - Rat 

Xp - Xenopus 

Ze - Zebrafish 

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related research tools including immunoprecipitation and labeling 

kits, stem cell lines and a variety of secondary antibodies, lysates, 

peptides and proteins. 

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G-Protein Coupled Receptors 

G-protein coupled receptors (GPCRs) have been implicated as signal transducers in a wide variety of 

physiological processes including sensory systems where they bind opsins, odorants and tastants. GPCRs also 

affect behavior and mood regulation through interaction with an array of neurotransmitters, including serotonin 

and dopamine. 

Purinergic Receptors 

Purinergic receptors bind derivatives of the nucleotide adenosine. Purinergic receptors have been implicated in 

a wide array of biological processes including modulation of peripheral auditory and visual sensory systems. 

Related Antibodies 

• Adenosine 

A1 Receptor 

• Adenosine 

A2a Receptor 

• Adenosine 

A2b Receptor 

• Adenosine 

A3 Receptor 

• GPR17 

• GPR86 

• P2RY1 

• P2Y2 

• P2Y4 

• P2Y6 

• P2Y8 

• P2Y10 

• P2Y11 

• P2Y12 

Adenosine A2a Receptor (7F6-G5-A2) 

Antibody 

NBP1-39474 

Immunohistochemical 

analysis of 

human brain 

using NBP1-39474. 

Species: Hu, Mu, Rt, Ca, GP, Rb 

Applications: WB, FACS, IHC-P 

GPR17 Antibody 

NLS4229 

Species: Hu 

Applications: IHC-P 

Adregergic Receptors 

The adrenergic receptors (adrenoceptors) are targets of catecholamines, excluding dopamine. 

Binding of an agonist to one of these receptors generally triggers a sympathetic (fight-or-flight) response. 


• Alpha 1 Adrenergic 

Receptor 

• Alpha 1b Adrenergic 

Receptor 

• Alpha 1d Adrenergic 

Receptor 

• Alpha 2a Adrenergic 

Receptor 

• Alpha 2b Adrenergic 

Receptor 

• Alpha 2c Adrenergic 

Receptor 

• Beta 1 Adrenergic 

Receptor 


Receptor 


Receptor 

Calcium-Sensing Receptor 

Calcium-sensing receptors (CaSRs) sense extracellular levels of calcium 

ions. The binding of calcium induces a conformational change in the 

receptor and triggers the phospholipase C pathway, ultimately increasing 

the intracellular concentration of calcium. 


analysis of human 

brain (neurons 

and glia) using 

NLS4229. 

Alpha 2a Adrenergic Receptor 

Antibody 

NBP1-67832 



testis tissue 


Species: Hu, Mu, Rt 

Applications: WB, ELISA, IF, IHC-P 

Calcium Sensing Receptor Antibody 

NBP1-84687 



pancreas using 

NBP1-84687. 

Species: Hu 

Applications: WB, IHC-P 

2

3 


5-Hydroxytryptamine Receptors 

5-hydroxytryptamine (5-HT) receptors, also known as serotonin receptors, are found in the central and peripheral 

nervous systems where they mediate neurotransmission and have been implicated in a wide array of biological 

and neurological processes including appetite, mood, nausea, sleep, and sexuality. 


• 5HT1A 

• 5HT1D 

• 5HT1E 

• 5HT1F 

• 5HT2A 

• 5HT2B 

• 5HT2C 

• 5HT5A 

• 5HT6 

• 5HTR7 

5-HTR1A Antibody 

NBP1-90321 


analysis of 

thymus, endothelial 

recticular cells 


Species: Hu 


5-HTR2C Antibody 

NBP1-90317 


analysis of 

human pancreas 


Species: Hu 

Applications: WB, IF, IHC-P 

Neuropeptide Receptors 

Neuropeptides function as intracellular signaling molecules and affect gene expression, local blood flow, 

synaptogenesis and glial cell morphology. Neuropeptides are packaged in large, dense-core vesicles and are 

located on every part of a neuron, including the soma, dendrites, axonal swellings and nerve endings. 


• GPR8 • NMUR1 

• GPR154 • NMUR2 

• Neurotensin • NPFFR1 

Receptor 1 • NPFFR2 

• Neurotensin • NPBWR1 

Receptor 2 • NPYR5 

• NMBR • NTSR2 

NMBR Antibody 

NBP1-89520 

Species: Hu 


NMUR1 Antibody 

NBP1-83433 

Immunofluorescent 

analysis showing 

positivityin plasma 

membrane & cytoplasm 


Species: Hu 



analysis of 

of human duodenum 


Bombesin Receptors 

This class of receptors is located largely in the central nervous system and the gastrointestinal tract. Bombesin 

receptors mediate the nuerological anxiety response as well as smooth muscle contraction and eating behavior. 

These ligands have also been implicated in many neurodegenerative diseases. 

Bombesin Receptor 3 Antibody 

NB100-74372 


analysis of 

human pancreatic 

carcinoma tissue 

sections using 

NB100-74372. 

Species: Hu 

Applications: WB, IHC, IHC-P 

Bombesin Receptor 3 Antibody 

NLS4915 


analysis of 

placenta 

using NLS4915. 

Species: Hu 


GRPR Antibody 

NB100-74434 

Species: Hu 




mammary carcinoma 

tissue using 

NB100-74434.


Muscarinic Acetylcholine Receptors 

Acetylcholine (ACh) is an abundant neurotransmitter, found in the central nervous system, autonomic preganglia 

and spinal motor neurons. There are two main subtypes of ACh receptors – nicotinic and muscarinic. Muscarinic 

receptors (mAChRs) are responsible for the post stimulation hyperpolarization and slow depolarization of the 

postganglionic neuron. mAChRs modulate an array of physiological functions, including smooth muscle 

contractions, heart rate, and glandular secretions 

Muscarinic Acetylcholine Receptor 2 

Antibody 

NBP1-86351 



kidney using 

NBP1-86351. 

Species: Hu 


Muscarinic Acetylcholine Receptor M4 

Antibody 

NBP1-70994 


analysis of LOVO 

cells using 

NBP1-70994. 


Applications: ELISA, IF 

Dopamine Receptors 

Many neurological responses are modulated by dopamine signaling. There are two families of dopamine 

receptors: the D1-like family (D1 and D5) and the D2-like family (D2 through D4). Activation of receptors in the 

D1-like family activates adenylyl cyclase, increasing the intracellular concentration of cAMP. Conversely, 

activation of receptors in the D2-like family inhibits the formation of cAMP by inhibiting adenylate cyclase. 

Customer Review 

Dopamine Receptor D1 Antibody 

(SG2-D1a)(NB110-60017) 

Application: IHC-Fr 

Sample Tested: Rat retinal whole 

mounts and sections 

Species: Rat 

Lot: A1 


NLS44 

Species: Hu 

Applications: ICC, IHC-P 


analysis of 

Kidney, Proximal & 

distal cinvoluted 

tubules using NLS44. 

Tuftelin 1 Antibody Antibody 

NBP1-87446 



duodenum using 

NBP1-87446. 

Species: Hu 



NBP1-87577 

Species: Hu 



analysis of 

human skin 


GABA-B Receptors 

GABA-B receptors are inhibitory receptors found in the central and peripheral autonomic nervous systems. 

Ligand binding triggers a signaling cascade that ultimately inhibits neurotransmitter release. GABA-B receptors 

may play important roles in the development and sensation of pain. 

GABA B Receptor 1 Antibody 

NBP1-52389 



brain cortex using 

NBP1-52389. 

Species: Hu, Mu, Rt, Bv, Ca 



NBP1-19356 



brain tissue using 

NBP1-19356. 




NBP1-89803 


analysis of 

human duodenum 


Species: Hu 


4

5 


Cannabinoid Receptors 

Cannabinoids are a group of 

terpenophenolic compounds 

present in the nervous and immune 

systems. There are two defined 

types of cannabinoid receptors, 

designated CB1 and CB2. CB1 

receptors are considered the 

most widely expressed GPCRs 

in the brain. 

Cannabinoid Receptor I Antibody 

NLS31 


analysis of 

brain, neurons 

using NLS31. 

Species: Hu, Rt, Mk 

Applications: ICC, IHC-Fr, IHC-P 

Cannabinoid Receptor II Antibody 

NBP1-88175 



hippocampus 


Species: Hu 


Histamine Receptors 

Histamine is a biogenic amine that is involved in local immune responses, digestive regulation and 

neurotransmission. 

Histamine Antibody 

NBP1-78351 


analysis of of rat 

hypothalamus 


Species: Hu, Rt, Dr, Le, Other 

Applications: IHC-Fr, IHC-P 

Histamine H4 Receptor Antibody 

NBP1-90058 



corpus, uterine 


Species: Hu 


Histamine receptor H3 Antibody 

NLS476 



transfection positive 

using NLS476. 

Species: Hu 


Vasopressin Receptors 

Vasopressin, also known as arginine vasopressin (AVP) or antidiuretic hormone (ADH), is a peptide hormone 

responsible for regulating the body’s retention of water, as well as a variety of neurological effects. 

AVPR1A Antibody 

NBP1-00157 

Western blot 

analysis of 

NIH3T3 lysate 


Species: Hu, Mu 

Applications: WB, PEP-ELISA 

AVPR1B Antibody 

NB100-96917 



anterior 

pituitary gland 

using NB100-96917. 

Species: Hu 

Applications: IHC, PEP-ELISA 

AVPR2 Antibody 

NBP1-71315 

Species: Hu 

Applications: WB, ELISA, IF 


analysis of MCF7 

cells using 

NBP1-71315. 

Somatostatin Receptors 

Somatostatin is a peptide hormone that interacts with G-protein coupled somatostatin receptors. Somatostatin is 

an inhibitory hormone that functions in regulation of the endocrine system, neurotransmission and cell 

proliferation. 

Somatostatin Receptor 1 Antibody 

NB300-120 

Western blot 

analysis from rat 

pancreas using 

NB300-120. 


Applications: WB, IP 


NB300-157 


analysis of rat 

tissue using 

NB300-157. 


Applications: WB, IF, IHC-Fr, IHC-P, IP 


NB100-74538 


analysis of 

human pancreatic 

islands using 

NB100-74538. 

Species: Hu 

Applications: WB, ICC, IHC-P


Latrophilin Receptors 

Latrophilin receptors are brain-specific, calcium-independent orphan GPCRs of the secretin family. Latrophilin-1 

and latrophilin-2 bind alpha-latrotoxin, a potent pre-synaptic neurotoxin present in the venom of black widow 

spiders. 

LPHN1 Antibody 

NBP1-71099 


Applications: ELISA, IF 


analysis of 

LOVO cells 



NBP1-71100 


Applications: ELISA, IF, IHC 



breast carcinoma 

tissue using 

NBP1-71100. 


NLS1138 

Species: Hu 



analysis of 

brain, neurons and 

glia using 

NLS1138. 

Brain-Specific Angiogenesis Inhibitors 

Brain-specific angiogenesis inhibitors (BAIs) are orphan GPCRs with unknown ligands. There are three BAI 

genes, which have similar tissue specificities and structures. BAI expression has been reported primarily in the 

brain. 

Customer Reviews 

BAI1 Antibody (NBP1-00723) 

Application: IF 

Sample Tested: THP1 cell line 

Species: Human 

BAI1 Antibody 

NB110-81586 



GHRH Receptor 

Growth hormone releasing hormone receptor 

(GHRHR), stimulates growth hormone (GH) 

secretion and synthesis in the pituitary gland. 

Mutations in GHRHR can cause either GH deficiency, 

resulting in dwarfism, or excessive production of GH, 

leading to gigantism. GHRHR is primarily 

expressed in the brain. 

GHRHR Antibody 

NB100-74424 


analysis in human 

ovarian carcinoma 

samples using 

NB100-74424. 

Species: Hu 

Applications: WB, ICC, IHC, IHC-P 


analysis of 

mouse brain 

using NB110-81536. 

BAI3 Antibody 

NBP1-82996 

Species: Hu 



analysis of 

human duodenum 


Parathyroid Hormone Receptors 

Parathyroid hormone receptors (PTHRs) bind 

parathyroid hormone (PTH), parathyroid hormone- 

related peptide (PTHRP), and tuberoinfundibular 

peptide 39. PTHR2 has only been identified in the 

brain. Due to its neuronal localization, PTHR2 is 

thought to function as a neurotransmitter receptor. 

Parathyroid Hormone Receptor 1 

Antibody (4D2) 

NBP1-51640 


analysis 

of SK-BR-3 cells 

using PTH1R 

mouse mAb (green) 


Species: Hu 


Parathyroid Hormone Receptor 2 

Antibody 

NLS250 


analysis of 

brain, neurons 

and glia using 

NLS250. 

Species: Hu 


6

7 

Signal Transduction 

Channels 

Channels are especially important in transmitting 

signals from sensory organs to the brain. Channels act 

both as receptors that transfer signals and as openings in 

the plasma membrane to allow chemicals such as 

potassium and calcium to move into and out of a cell. 

Cav1.2 Antibody 

NBP1-42817 

Kv1.2 Antibody 

NBP1-42802 

TRPA1 Antibody 

NB110-40763 


Applications: WB, IHC, IHC-P 

NMDA Receptors 

NMDA receptors are ionotropic glutamate 

receptors that regulate the opening and closing of 

ion channels that control the flux of Ca 2+ , K + , and 

Na + into and out of cells. NMDA receptor interactions 

are crucial to proper cellular function and communication, 

especially in neurons. Malfunctioning NMDA receptors 

may be a crucial factor in Huntington’s Disease. 

NMDA receptor N1 Antibody 

NB300-114 

Western blot 

analysis of 

HEK 293 cells 

using NB300-114. 


Applications: WB, DB, IHC-Fr 


Immunocyctochemical 

analysis in 

mouse 3T3 

fibroblasts using 

NBP1-42817. 

Species: Hu, Mu, Rt, Bv, Ca, Rb 

Applications: WB, ICC, IF, IP 

Immunocyctochemical 

analysis in 293 

human embryonic 

kidney cells using 

NBP1-42802. 

Species: Hu, Mu, Rt, Bv, Ca, Po, Xp, Ze 

Applications: WB, ICC 

NMDAR1 Antibody (NB100-74473) 


Sample Tested: Tissue sections 

of mouse brain 

Species: Mouse 

KCNH1 Antibody 

NBP1-42816 

Species: Hu, Mu, Rt, Bv 

Applications: WB, ICC, IF, IP 


analysis of mouse 

intestine using 

NB110-40763. 

NMDAR1 Antibody 

NBP1-20085 


analysis of 

human spinal 

cord tissue using 

NBP1-20085. 



Western blot 

analysis 

in HEK 

cells using 

NBP1-42816. 

NMDAR1 Antibody (NB100-92192) 

Application: IHC-P 

Sample Tested: Rat 

Species: Rat 


• 5HT3A 

Receptor 

• ATP5E 

• CACNB4 

• Cav1.2 

• KCNH1 

• Kv1 

• Kv1.2 

• Kv1.3 


TRPM2 Antibody 

NB110-81601 

• NMDAR2B 

• NMDA Receptor C1 

• NMDA Receptor N1 

• NMDAR1 

• NMDAR2A 

• NMDAR1 

• Potassium voltagegated 

channel 

• TREK 1 

• TRPA1 

• TRPC3 

• TRPC4 

• TRPC5 

• TRPM2 

Species: Mu, Rt 

Applications: WB, ICC, IF, IHC 

Immunocytochemical 

analysis of 

rat hippocampus 

using NB110-81601. 

• NMDAR2C 

• NMDAR2D 

• NMDAR3A 

• NMDAR3B 

• NMDARA1 

NMDAR2B Antibody 

NBP2-12999 


analysis of 

human brain 

tissue using 

NBP2-12999. 

Species: Hu 


NMDAR2B Antibody (NB300-106) 


Sample Tested: Rat brain tissue 

Species: Other 

Other Species: Donkey anti-rabbit

Signaling Proteins 

Signaling proteins facilitate the cellular implementation of messages received from other cells and organ 

systems, providing a transition between neurons and the cells that they affect. 


• Calmodulin • SNAP25 

• Calreticulin • Striatin 

• RGS1 • Synaptotagmin 

Calreticulin (1G6A7) Antibody 

NBP1-47518 


analysis of 3T3-L1 

cells using 

NBP1-47518. 


Applications: WB, ELISA, IF 

Striatin Antibody 

NB110-74571 


Applications: WB, IF, IP 

Product Citations 


analysis of 

NIH3T3 cells using 

NB110-74571. 

Calmodulin (2D1) Antibody 

NB120-2860 


analysis in 

rat brain using 

NB120-2860. 

Species: Rt, Ba, Bv, Ch 

Applications: WB, ELISA, ICC, IF 

RGS1 Antibody 

NBP1-68645 


Applications: ELISA, IHC-P 


analysis of 

human colon 



Synaptotagmin 1 Antibody 

NBP1-61218 


analysis of 

human breast 




Applications: WB, ELISA, IHC 

Calreticulin Antibody 

NB600-101 

Western blot 

analysis 

on human 

kidney lysate using 

NB600-101. 


Applications: WB, ICC, IF, IHC 

SNAP25 Antibody 

NBP1-88769 


analysis of 

human cerebral 

cortex using 

NBP1-88769. 

Species: Hu 


Synaptotagmin 2 Antibody 

NBP1-90356 


analysis of 

human 

stomach using 

NBP1-90356. 

Species: Hu 


[NMDAR1 (R1JHL) Antibody NB300-118] Tao P-L, Chen C-F, Huang EY-K. Dextromethorphan attenuated the 

higher vulnerability to inflammatory thermal hyperalgesia caused by prenatal morphine exposure in rat offspring. 

J Biomed Sci. 2011 Aug 23;18(1):64. [PMID: 21861871] 

[NMDAR2B Antibody NB300-106] Tse YC, Bagot RC, Hutter JA, et al. Modulation of Synaptic Plasticity by Stress 

Hormone Associates with Plastic Alteration of Synaptic NMDA Receptor in the Adult Hippocampus. PLoS ONE. 

2011 6(11). [PMID: 22069501] 

[NMDAR2B Antibody NB300-106 and NMDAR2B Antibody NB300-116] Das SR, Magnusson KR. Changes in 

expression of splice cassettes of NMDA receptor GluN1 subunits within the frontal lobe and memory in mice 

during aging. Behav. Brain Res. 2011 Sep 12;222(1):122-133. [PMID: 21443909] 

[SNAP25 Antibody NB100-1492] Guedj F, Pereira PL, Najas S, et al. DYRK1A: A master regulatory protein 

controlling brain growth. Neurobiology of Disease. 2012 Jan 26. [PMID: 22293606] 

[TRPM2 Antibody NB110-81601] Bai JZ, Lipski J. Differential expression of TRPM2 and TRPV4 channels and their 

potential role in oxidative stress-induced cell death in organotypic hippocampal culture. Neurotoxicology. 2010 

Jan 12. [PMID: 20064552] 

[TRPM2 Antibody NB110-81601and TRPM2 Antibody NB500-242] Chung KK, Freestone PS, Lipski JL. The 

expression and functional properties of TRPM2 channels in dopaminergic neurons of the substantia nigra of the 

rat. J Neurophysiol. 2011 Sep 7. [PMID: 21900507] 

8

9 

Epigenetic Regulation 

Chromatin modification and DNA-modifying enzymes have been shown to regulate various pathways in the 

development and function of the nervous system. Several areas of epigentics control of neural activity actively 

studied include histone acetylation and DNA methylation in response to neutrotrophin signaling as well as how 

DNA methylation, histone modification and transcriptional feedback loops promote self-renewal and 

differentiation of adult neural stem cells. [PMID: 20975746] 


• alpha-Synuclein 

• Amyloid beta 

Precursor Protein 

• BACE1 

• BDNF 

• beta Amyloid 

• c-FOS 

• Gamma-secretase 

• GNAT 

• Histone H3 


[Monomethyl Lys9] 

beta Amyloid (MOAB-2) Antibody 

NBP2-13075 

Western blot 

analysis of beta 

Amyloid in 

HEK-APP 

SWE/BACE1 cells 



Applications: WB, ELISA, ICC, IF, IHC-P, IP 

Histone Acetyltransferase 

Antibodies 

• AIB1 

• CLOCK 

• ELP3 

• KAT1 

• KAT2A 

• KAT3A/CBP 

• KAT3B/p300 

• KAT6B-MORF 


[Trimethyl Lys9] 


• Huntingtin 

• MeCP2 

• NFkB 

• NRSF 

• p21 

• REST 

• SETDB1 

• SMCX 

• MYST1 

• MYST3 

• NCOA2 

• PCAF 

• SRC1 

• TAF1 

• TIP60 


FOS Antibody (NB100-91772) 

Application: IHC 

Sample Tested: Mouse 

Sample Pretreatment: Citrate 

buffer 


MeCP2 Antibody (NB600-1101) 

Application: Western blot 

Sample Tested: iPS (Induced 

Pluripotent stem cells derived 

from AFMSC) 

Sample Pretreatment: Lysis buffer 


Histone H3 [Sym-dimethyl Arg2, 

Dimethyl Lys4] Antibody 

NB21-1202 

Chromatin from one 

million formaldehyde 

cross-linked Hela 

cells was used with 

2 ug of NB21-1202. 

Species: Hu, Mu, Ce 

Applications: WB, ChIP, DB, ICC, IF 

CLOCK Antibody 

NB100-126 


Applications: WB, ChIP 

KAT3B/p300 (RW128) Antibody 

NB100-507 

Species: Hu, Mu, Rt, Mk 

Applications: WB, IF, IP 

Western blot 

analysis of 

alpha CLOCK 

immunoprecipitated 

DNA using 

NB100-126. 

Western blot 

analysis of p300 

in a HeLa nuclear 

exctract using 

NB100-507. 

Histone H3 Antibody (NB500-267) 


Sample Tested: HeLa cell lysates 

Sample Pretreatment: 50 ug 

Species: Rat 

p21 Antibody (WA-1) 

(NB500-303) 


Sample Tested: Horse skin 


Species: Equine 

Histone H3 [Dimethyl Lys9] Antibody 

NB21-1072 

Western blot 

analysis of 

H3K9me2 

in C. elegans 

embryo lysate using 

NB21-1072. 

Species: Hu, Mu, Rt, Ce, Ma 

Applications: WB, ChIP, DB, ICC, IF 

Customer Review 

KAT3A/CBP Antibody (NB100-381) 

Application: IP 

Sample Tested: HeLa cell lysates 


TIP60 Antibody 

NBP1-61537 


Applications: ELISA, IF, IHC 



liver carcinoma 

tissue using 

NBP1-61537.

Histone Deacetylase Antibodies 

• HDAC1 

• HDAC2 

• HDAC3 

• HDAC4 

• HDAC5 

• HDAC6 

• HDAC7 

• HDAC8 

• HDAC9 

• HDAC10 

Epi-Plus® 


• HDAC11 

• Sir2.1 

• SIRT1 

• SIRT2 

• SIRT3 

• SIRT4 

• SIRT5 

• SIRT6 

• SIRT7 

HDAC2 Antibody 

NBP1-87109 

Species: Hu 


SIRT1 Antibody 

NBP1-49540 

Species: Hu 

Applications: IHC, WB 



positivity in nuclei 


Immuno- 

histochemical 

analysis in 

human renal cell 

carcinoma using 

NBP1-49540. 

HDAC6 Antibody 

NBP1-78981 

Species: Hu 

Applications: IF, ICC 

SIRT6 Antibody 

NB100-2522 

Species: Mu 

Applications: IHC-P, WB 


analysis in HeLa 

cells with FITC 

(green) using 

NBP1-78981. 


analysis of 

human testes 

tissue using 

NB100-2522. 

Novus offers our Epi-Plus antibodies for modified histones. All Epi-Plus 

antibodies are multi-assay validated, including testing by dot blots using modified 

peptide arrays, western blots, and chromatin immunoprecipitation (ChIP). 

Learn more at www.novusbio.com/epi-plus.html 

[alpha-Synuclein (24.8) [Nitrate Tyr123, Nitrate Tyr133] Antibody NBP1-26380] Huang Z, Xu Z, Wu Y, Zhou Y. 

Determining nuclear localization of alpha-synuclein in mouse brains. Neuroscience. 2011 Oct 19. 

[PMID: 22033456] 

[BACE1 NB120-2077] Chang W, Barnes AM, Cabral WA, et al. Prolyl 3-hydroxylase 1 and CRTAP are mutually 

stabilizing in the endoplasmic reticulum collagen prolyl 3-hydroxylation complex. Hum Mol Genet. 2010 Jan 

15;19(2):223-34. [PMID: 19846465] 

[CLOCK Antibody NB100-126] Xu CX, Krager SL, Liao DF, et al. Disruption of CLOCK-BMAL1 transcriptional 

activity is responsible for aryl hydrocarbon receptor-mediated regulation of Period1 gene. Toxicol Sci. 2010 

May;115(1):98-108. [PMID: 20106950] 

[Histone H3 Antibody NB500-171] Liu R, Lei JX, Luo C, et al. Increased EID1 nuclear translocation impairs 

synaptic plasticity and memory function associated with pathogenesis of Alzheimer’s disease. Neurobiology of 

Disease. 2012 45(3):902-912. [PMID: 22186421] 

[Histone H3 [Asym-dimethyl Arg8] Antibody NB21-1062] Blythe SA, et al. beta-Catenin primes organizer gene 

expression by recruiting a histone H3 arginine 8 methyltransferase, Prmt2. Dev Cell. 2010 Aug 17;19(2):220- 

31. [PMID: 20708585] 

[Histone H3 [Dimethyl Lys36] Antibody NB21-1252] Hsia DA, et al. KDM8, a H3K36me2 histone demethylase 

that acts in the cyclin A1 coding region to regulate cancer cell proliferation. Proc Natl Acad Sci U S A. 2010 May 

25;107(21):9671-6. [PMID: 20457893] 

[Histone H3 [p Thr3, Monomethyl Lys4] Antibody NB21-1012] Metzger E. et al, Phosphorylation of 

histone H3T6 by PKCbeta(I) controls demethylation at histone H3K4. Nature. 2010 Apr 1;464(7289):792-6. 

[PMID:20228790] 

[KAT3B/p300 Antibody NB500-161] Luo W, Hu H, Chang R, et al. Pyruvate Kinase M2 is a PHD3-Stimulated 

Coactivator for Hypoxia-Inducible Factor 1. Cell. 2011 May 27;145(5):732-44. [PMID: 21620138] 

[p21 (WA-1) Antibody NB500-303] Deschene K, Céleste C, Boerboom D, Theoret CL. Constitutive 

expression of hypoxia-inducible factor-1 a in keratinocytes during the repair of skin wounds in horses. Wound 

Repair Regen. 2011 Mar-Apr;19(2):250-9. [PMID: 21362093] 

[SETDB1 Antibody NBP1-84790] Ceol CJ, et al. The histone methyltransferase SETDB1 is recurrently amplified in 

melanoma and accelerates its onset. Nature. 2011 Mar 24;471(7339):513-7. [PMID: 21430779] 

[SMCX Antibody NB100-55328] M. L. C. Powell, J. A. Smith, M. E. Sowa, et al. NCoR1 Mediates Papillomavirus 

E8^E2C Transcriptional Repression. J. Virol. 2010 84 (9): 4451-4460. [PMID: 20181716] 

10

11 

Neurogenesis and Gliogenesis 

Neurogeneisis is the formation of new neuronal cells. Once thought only to occur in developing organisms, 

recent studies have shown that neurogeneis occurs through an organism’s lifespan and plays a crucial role in 

neuron plasticity. Gliogeneisis is the formation of non-neuronal glia population. Glia cells function to support 

neural cells by providing physical structure and insulation, supplying nutrients and destroying pathogens. The 

Notch signaling pathway plays a major regulatory role in both events which are also affected by the Wnt and 

SHH pathways. Disruption of these processes has been implicated in several neurodegenerative diseases 

including Parkinson’s and Multiple Sclerosis. 


• AKT 

• alpha Catenin 

• Axin 1, 2 

• beta Catenin 

• CCL12 

• CCL2 

• CNTF 

• CSPG4P5 

• Delta 1, 3, 4 

• Dishevelled 

• EGF 

• Eotaxin 

• FGF 

• GABA 

• gamma-Secretase 

• GFAP 

• Glutamate Receptor 5 

• HIP1 

• IGF1 

Delta 1, 3, 4 

Jagged 1, 2 

Notch 1, 2, 3, 4 

• IGF1 Receptor 

• Jagged 1, 2 

• JAK 1, 2, 3 

• LRP2 

• LRP5/6 

• MASH1 

• Neurogenin 1 

• NMDA 

• Notch1 

• NRG1 

• NUMB 

• OLIG2 

• PACAP Receptor 

• Sonic Hedgehog 

• SS18L1 

• Stat 1–6 

• TGF alpha 

• VIP 

• Wnt 

Overview of the Notch Signaling Pathway 

γ-Secretase 

NICD 

HDAC CoR 

CSL 

X 

CoA 

MAML 

p300 

NICD 

CSL 


PPAR delta Antibody (NB600-637) 

Application: IHC-P 

Sample Tested: Gerbil stomach 

Species: Gerbil 

AKT1 Antibody (NB600-467) 


Sample Tested: Mouse spleen lysate 


FGFR1 Antibody (M19B2) (NB600-1287) 

Application: FACS 

Sample Tested: Transfected cell line 

Species: Rat 

Notch 1 Antibody 

NBP1-78292 





kidney using 

NBP1-78292.

eta Catenin Antibody (12F7) Antibody 

NBP1-54467 

IGF1 Receptor Antibody 

NBP1-77679 

NUMB Antibody 

NB500-178 

Western blot 

analysis in 

1. HepG2, 2. MCF7, 

and 3. Cos7 whole 

cell lysates using 

NBP1-54467. 

Species: Hu, Mu, Rt, Ch, Mk 

Applications: WB, ICC, IF, IHC-P, IP 


Applications: WB, ICC, IF, IHC-P 

Species: Hu, Mu, Rt, Ch 

Applications: WB 



analysis in A431 cells 

with FITC (green) 


Western blot 

analysis of isoforms 1 

and 2 in A431 whole 

cell lysate using 

NB500-178. 

Dishevelled 3 Antibody 

NBP1-68660 


analysis of 

human brain 

tissue using 

NBP1-68600. 


Applications: ELISA, IHC 

Jagged1 Antibody 

NB600-1161 


analysis of 

human corneal 

epithelial cells 

using NB600-1161. 



Sonic Hedgehog Antibody 

NBP1-69270 


analysis of 

chicken embryos 


Species: Hu, Mu, Rt, Ca, Ch, Xp, Ze 


HIP1 (4B10) Antibody 

NB300-203 

Western blot 

on HeLa whole 

cell extracts 

using 

NB300-203. 

Species: Hu 


Neurogenin 1 (3F9) Antibody 

NBP1-47871 


analysis 

of prostate tissue 


Species: Hu 


Wnt1 (10C8) Antibody 

NBP1-51575 


analysis of 3T3-L1 

cells using 

NBP1-51575. 


Applications: WB, ELISA, FACS, IF, IHC-P 

[AKT2 Antibody NBP1-26594] Lin HP, Jiang SS, Chuu CP. Caffeic Acid Phenethyl Ester Causes p21 

Induction, Akt Signaling Reduction, and Growth Inhibition in PC-3 Human Prostate Cancer Cells. PLoS One. 

2012;7(2). [PMID: 22347457] 

[EGFR Antibody (29.1) NB120-10414] Kondratov, K.A., et al., Termination Of Tyrphostin AG1478 Application 

Results In Different Recovery Of EGF Receptor Tyrosine Residues 1045 And 1173 Phosphorylation In A431 Cells. 

Cell Biol. Int. 2010 34:81-87. [PMID: 19947936] 

[GABA A Receptor gamma 2 Antibody NBP1-52033] You IJ, Jung YH, Kim MJ, et al. Alterations in the emotional 

and memory behavioral phenotypes of transient receptor potential vanilloid type 1-deficient mice are 

mediated by changes in expression of 5-HT 1 A, GABA(A), and NMDA receptors. Neuropharmacology. 2012 

Feb;62(2):1034-43. [PMID: 22074644] 

[GABA B Receptor 1 Antibody NB300-160] Luo C, Rajput AH, Robinson CA, Rajput A. Gamma- 

aminobutyric acid (GABA)-B receptor 1 in cerebellar cortex of essential tremor. J Clin Neurosci. 2012 Feb 7. 

[PMID: 22321358] 

[GABARAP Antibody NB300-158] Diaz MR, Christian DT, Anderson NJ, McCool BA. Chronic ethanol and 

withdrawal differentially modulate lateral/basolateral amygdala paracapsular and local GABAergic synapses. J. 

Pharmacol. Exp. Ther. 2011 Apr;337(1):162-170. [PMID: 21209156] 

[GFAP Antibody NB300-141] O’Donnell LA, Conway S, Rose RW, et al. STAT1-Independent Control of a 

Neurotropic Measles Virus Challenge in Primary Neurons and Infected Mice. J Immunol. 2012 Feb 

15;188(4):1915-23. [PMID: 22246627] 

[HIP1 (1B11) Antibody NB300-204] Datta M, Bhattacharyya NP. Regulation of RE1 Protein Silencing Transcription 

Factor (REST) Expression by HIP1 Protein Interactor (HIPPI). J Biol Chem. 2011 Sep 30;286(39). 

[PMID: 21832040] 

[Notch1 Antibody NB300-251] Sciacca S, Pilato M, Mazzoccoli G, Pazienza V, Vinciguerra M. Anti-correlation 

between longevity gene SirT1 and Notch signaling in ascending aorta biopsies from patients with bicuspid aortic 

valve disease. Heart Vessels. 2012 Feb 28. [PMID: 22370592] 

[PKC delta (K15-K) Antibody NBP1-30125] Ku CS, Park Y, Coleman SL, Lee J. Unsaturated fatty acids repress 

expression of ATP binding cassette transporter A1 and G1 in RAW 264.7 macrophages. The Journal of 

Nutritional Biochemistry. 2011 Dec 29. [PMID: 22209005] 

12

13 

Axon Function and Structure 

Axons are the part of a neuronal cell that carries signals away from the soma. For a given neuronal cell type, 

axons may vary greatly and undergo extensive branching. Axonal growth is stimulated by a variety of 

neutrophic growth factors (NTFs) and also regulated by Src family kinases (SFKs). [PMID: 17646673] Guidepost 

cells assist in axon growth and play a role in neuroregeneration, in which damaged axons regenerate synaptic 

connections with other neurons. Under normal physiological conditions, “axon-pruning” occurs as a 

mechanism to maintain connectivity and plasticity and also to repair damaged axons. [PMID: 16022592] Axon 

loss contributes to neurological symptoms in disorders including multiple sclerosis, stroke and chronic neurodegenerative 

diseases. [PMID: 12220882] 


• alpha 2 

Mannosidase 2A 

• BDNF 

• BLK 

• ChABC 

• F-actin 

• FGR 

• FRK 

• Fyn 

• GDNF 

• GFAP 

• Gigaxonin 

ChABC (6A12) Antibody 

NBP1-96141 

Western blot 

analysis of 

Chondroitinase 

ABC using 

NBP1-96141. 

Species: NA 

Applications: WB, ELISA 

Mitofusin-1 Antibody 

NBP1-51841 


analysis of 

mouse intestine 



Applications: ICC, IF, IHC-P 


• GNB5 

• Hck 

• Laminin 

• Lck 

• Lyn 

• Mitofusin 1, 2 

• Myelin Protein Zero 

• Netrin 1 

• Netrin-G1 Ligand 

• Neurotrophin 3 

• Neurotrophin 4 

• Neurturin 

BLK Antibody (7A12) (H00000640-M02) 


Sample Tested: Recombinant (r) BLK, 

Ramos whole cell lysate, Jurkat whole 

cell lysate 


GFAP Antibody 

NB300-141 

• NGF 

• p75NTR 

• PMP22 

• Src 

• TDP1 

• TNF alpha 

• TrkA 

• TrkB 

• TrkC 

• Yes1 

PMP22 (Hu1) Antibody 

NB110-59086 


analysis in dorsal 

root ganglion and 

spinal roots in 20 

week fetal spinal 

Species: Hu, Mk 



analysis of mixed 

neuron glial cultures 


Species: Hu, Mu, Rt, Bv, Fe, Po 

Applications: WB, ICC, IF, IHC-Fr, IHC-P 

cord using 

NB110-59086. 

Laminin Antibody (NB300-144) 



Sample Pretreatment: Doxorubicin 

Species: Rat 

Dendrite 

Cell body 

Myelin sheath 

(Schwann cell) 

Node of Ranvier 

Axon 

Axon terminals 

Laminin Antibody 

NB300-144 


analysis in 

Hela cells (green) 



Applications: WB, ICC, IHC-Fr, IHC-P 

Src [p Tyr418] Antibody 

NBP1-60970 


analysis 

human colon 



Applications: WB, WB, ELISA, IHC-P 

Src [p Tyr418] Antibody (NB100-92633) 



Species: Rat

Sensory Systems: Auditory & Olfactory 

Auditory 

Hearing is a complex interaction between many structures of the ear that amplify sound vibrations, convert 

vibrations into electrical signals, and then carry those signals to the brain. Neurotransmitters convey signals from 

the hair cells of the inner ear to auditory neurons. The encoded message travels through multiple areas of the 

brain until it is relayed to the primary auditory cortex via the temporal lobe. Defects in certain hearing related 

proteins have been associated with hearing loss; these proteins include Tubby, Myosin 1C and proteins 

associated with Waardenburg syndrome (PAX3, MITF, EDNRB, EDN3 and SOX10.) 


• ARC 

• Connexin 26 

• Endothelin 

• Endothelin 3 

• MiTF 

• Myosin 1C 

• PAX3 

• Tubby 

• TULP1 

• TULP2 

• TULP3 

• TULP4 

Myosin 1C Antibody 

NBP1-87745 


analysis of 

human gall 

bladder using 

NBP1-87745. 

Species: Hu 


Tubby Antibody 

NB100-1922 

Species: Ce 

Applications: WB, IHC-P, IP 

Western blot 

analysis of tub-1 

(GFP complex) using 

NB100-1922. 

Olfactory 

The initial olfactory signal is initiated when an odorant molecule binds to an olfactory receptor which triggers the 

activation of a G-protein signal cascade. Olfactory receptors are GPCRs similar to those known to be important 

in neurotransmission and photoreception; there are as many as 1,000 genes for ORs in the mammalian 

genome. [PMID: 17903277] 


• Adenylyl Cyclase 3 

• Cyclic AMP 

• F-Actin 

• GABA A Receptor alpha 1 

• MAP2 

• NKCC1 

• Phospholipase C beta 2 

• TRPC6 


Adenylate Cyclase 3 Antibody 

NBP1-92683 

Immunofluorecent 

analysis of 

Mixed neuron-glial 

cultures using 

NBP1-92683. 

Species: Hu, Rt 

Applications: WB, IF 

MAP2 Antibody 

NB300-213 


Applications: WB, IF, IHC-Fr 


analysis of 

mixed neuron/glial 

cultures using 

NB300-213. 

Novus offers hundreds of antibodies for ORs. Visit www.novusbio.com 

and search on your gene of interest to find related products. 

[Endothelin A Receptor Antibody NB600-836] Marroquin Belaunzaran O, Cordero MI, Setola V, Bianchi S, 

Galli C, Bouche N, Mlynarik V, Gruetter R, Sandi C, Bensadoun JC, Molinari M, Aebischer P. Chronic delivery 

of antibody fragments using immunoisolated cell implants as a passive vaccination tool. PLoS One. 2011 Apr 

20;6(4):e18268. [PMID: 21533130] 

[MAP2 Antibody NB300-213] Schätzle P, Wuttke R, Ziegler U, Sonderegger P. Automated quantification of 

synapses by fluorescence microscopy. Journal of Neuroscience Methods. 2011 Nov 11204(1):144-149. 

[PMID: 22108140] 

[MAP2 Antibody NB300-213] Sur S, Pashuck ET, Guler MO, et al. A hybrid nanofiber matrix to control the 

survival and maturation of brain neurons. Biomaterials. 2011 Oct 19. [PMID: 22018390] 

14

15 

Sensory Systems: Vision 

Vision 

Vision is a complex process involving interactions between the surface and lens of the eye, the retina and neural 

receptors and the processing by the brain of information collected from the eyes. Because there are many 

processes involved in eyesight, a wide range of genes are involved in the processes of collecting, relaying, and 

processing visual signals. Likewise, mutations to any of these genes can cause problems in a variety of areas 

including ocular development, retinal development or degeneration, or signal transmission to the brain. 


• 3-OHKYN 

• Adenosine A1 Receptor 

• Adenylate Cyclase 6 

• ALDH1A3 

• APXL 

• Arrestin 3 Retinal 

• BBS10 

• Bestrophin 

• betaTrCP 

• BMAL1 

• CACNA2D4 

• Calnexin 

• CaMK1 

• Cannabinoid Receptor II 

• CD147 

• CEP290 

• Ceramide Kinase Like 

• CHX10 

• clarin 1 

• CLOCK 

• CNNM4 

• Crystallin AB 

• Cytokeratin 3/12 

• Dock5 

• EFEMP1 


Mucolipin 1 Antibody (NB110-82375) 


Sample Tested: HEK lysate overexpressing 

mcoln1 

• ELAVL2 

• EYA3 

• EYA4 

• FOXE3 

• GDF6 

• Glutamate Receptor 1 

• Glutamate receptor 2 

• Glutamate receptor 2/3 

• Glutamine Synthetase 

• Homeobox protein SIX6 

• IMPG2 

• LRP5/6 

• Melanopsin 

• MERTK 

• Metabotropic Glutamate Receptor 

• mGluR1 

• mGluR6/7 

• Mucolipin 1 

• Ndufs1 

• NIR2 

• OPA1 

• Opsin 1 (Medium Wave) 

• Opsin 3 

• Otx2 

• OTX3 

OPA1 Antibody (NB110-55290) 


Sample Tested: COS-1 cell 

• PAX6 

• PDE6A 

• PER1 

• Peropsin 

• PROX1 

• PRPF3 

• PRPF8 

• Retinoic Acid Receptor alpha 

• Retinoic Acid Receptor beta 

• RGR 

• Rhodopsin 

• RIT1 

• RPE65 

• S Opsin 

• S-arrestin 

• SHH 

• SNAP25 

• SOX2 

• Syntrophin 

• Syntrophin alpha 1 

• Transducin alpha 

• Transducin beta 

• TULP1 

• WDR36 

• WFS1 

SOX2 Antibody (NB110-37235) 


Sample Tested: Oral cancer cell line 

Species: Human

3-OHKYN (P3UI) Antibody 

NB100-597 

Western blot 

analysis in 

modified BSA 


Species: Hu, All 

Applications: WB, ICC 

Crystallin AB Antibody 

NB100-2520 

Western blot 

of Lane 1: human 

skeletal muscle and 

Lane 2: mouse skeletal 

muscle proteins 

using NB100-2520. 



Mucolipin 1 Antibody 

NB110-82375 

Western blot 

analysis in 

in mouse brain 

lysates using 

NB110-82375. 




Calnexin Antibody 

NB100-1974 


analysis in 

mouse bladder 

using NB100-1974. 



Cytokeratin 19 Antibody 

NBP1-78278 


analysis human 

kidney carcinoma 




OPA1 Antibody 

NB110-55290 


analysis in 

prostatic smooth 

muscle using 

NB110-55290. 

Species: Hu, Mu, Rt, Ch, Mk, Ze 

Applications: WB, IHC 

Ceramide Kinase Antibody 

NB100-2911 

Species: Hu 


Western blot 

analysis in 

A549 cell lysate 

using NB100-2911. 

Metabotropic Glutamate Receptor 6 

Antibody 

NB300-189 

Immunofluorecent 

analysis in trapezoid 

body in mouse brain 



Applications: WB, IF 

RPE65 (401.8B11.3D9) Antibody 

NB100-355 


analysis in mouse 

retina tissue using 

NB100-355. 

Species: Hu, Mu, Bv, Po 

Applications: WB, ICC, IF, IHC, IHC-Fr 

[Adenylate Cyclase 3 Antibody NBP1-92683] Louvi A and Grove EA. Cilia in the CNS: the quiet organelle claims 

center stage. Neuron 2011 69:1046-1060. [PMID: 21435552] 

[Crystallin AB (1B6.1-3G4) Antibody NBP1-97494] Schwirtlich M, Kwakowsky A, Emri Z, et al. GABAergic 

signaling in primary lens epithelial and lentoid cells and its involvement in intracellular Ca2+ modulation. Cell 

Calcium. 2011 Aug 3. [PMID: 21820173] 

[Calnexin (1D4) Antibody H00000821-M08] Teoh KT, Siu YL, Chan WL et al. The SARS coronavirus E protein 

interacts with PALS1 and alters tight junction formation and epithelial morphogenesis. Mol Biol Cell. 2010 

Nov;21(22):3838-52. [PMID: 20861307] 

[Cannabinoid Receptor II Antibody NB300-606] Patsenker E, Stoll M, Millonig G, et al. Cannabinoid Receptor 

Type I Modulates Alcohol-Induced Liver Fibrosis. Mol Med. 2011 Aug 19. [PMID: 21863215] 

[CEP290 Antibody NB100-86991] Hopp K, Heyer CM, Hommerding CJ, et al. B9D1 is revealed as a novel 

Meckel syndrome (MKS) gene by targeted exon-enriched next-generation sequencing and deletion analysis. 

Hum Mol Genet. 2011 Apr 14. [PMID: 21493627] 

[ELAVL2 Antibody NB110-10865 ] Hayakawa H, Fujikane A, Ito R, et al. Human proteins that specifically bind 

to 8-oxoguanine-containing RNA and their responses to oxidative stress. Biochem Biophys Res Commun. 2010 

Nov 10. [PMID: 21073862] 

[OPA1 Antibody NB110-55290] Trushina E, Nemutlu E, Zhang S, Christensen T, Camp J, et al. Defects in 

Mitochondrial Dynamics and Metabolomic Signatures of Evolving Energetic Stress in Mouse Models of Familial 

Alzheimer’s Disease. PLoS ONE. 2012 7(2). [PMID: 22393443] 

[Rhodopsin (4D2) Antibody NBP1-48334] Matsuyama T, Yamashita T, Imai H, Shichida Y. Covalent 

bond between ligand and receptor required for efficient activation in rhodopsin. J Biol Chem. 2010 Mar 

12;285(11):8114-21. [PMID: 20042594] 

16

17 

CNS Control of Metabolism 

Circadian Rhythms 

Sleep cycles are regulated through both circadian and homeostatic processes. The biological clock genes are 

well conserved across species. Circadian rhythms are thought to be controlled by the interactions of a relatively 

small set of proteins. Gene variations and genetic defects in these proteins can lead to sleep disorders and poor 

adaptations to the light-dark cycle. [PMID: 17299246] 


• BMAL1 

• Casein Kinase 

1 delta 

• CLOCK 

• Cryptochrome I 

• CRY2 

• PER2 

• PER3 

• Timeless 

CRY2 Antibody 

NBP1-86273 

Species: Hu 


Immunofluorscent 


positivity in nuclues 

& cytoplasm using 

NBP1-86273. 

Timeless Antibody 

NB100-40853 


analysis of 

breast carcinoma 



Applications: WB, IF, IHC-P, IP 

Food Intake 

Food intake is controlled by a highly complex process. Compounds that affect food intake and that are critical 

for normal energy homeostasis are termed adiposity signaling molecules. Several neuropeptide and 

neurotransmitters have been identified as molecules that act through intermediaries as adiposity signals 

including Leptin, Insulin, Neuropeptide Y, Melanocortins, Noradrenaline, Dopamine, Serotonin. 

[PMID: 10766253] 


• AGRP 

• Alpha-MSH 

• CARTPT 

• Corticotropin 

Releasing Factor 

• CRHBP 

• Galanin 

• GALP 

• GalR1, 2, 3 

• GLP1R 

• IL1 beta 

• Insulin 

• Insulin Receptor 

• Insulin Receptor beta 

• IR-related receptor 

• Leptin 

• Leptin Receptor 

• MCHR 

• MCHR1 

• MCHR2 

• MRAP2 

• Neuropeptide Y 

• Neurotensin 

• Neurotensin Receptors 1, 2 

• Noradrenaline transporter 

• NPY1R 

• NPY2R 

• NPY4R 

• NPY5R 

• Orexin 

• Orexin A 

• Orexin Receptors 1, 1/2, 2 

• Oxytocin 

• Oxytocin Receptor 

• Serotonin 

• Thyrotropin Releasing 

Hormone 

• Urocortin 

GLP1R Antibody 

NBP1-97308 


analysis in 

mouse pancreas 




Insulin Receptor [p Tyr1361] Antibody 

NBP1-51404 


analysis in 

human breast 





Neuropeptide Y Antibody 

NBP1-78352 


analysis in 

the rat central 

nervous system 


Species: Hu, Mu, Rt, Am, Av, Fe, Fi, GP, 

Other, Ze 

Applications: ICC, IHC-Fr, IHC-P

Alzheimer’s Disease 

Alzheimer’s Disease (AD) is a progressive neurodegenerative condition that affects mental capacity, especially 

memory and behavior. AD is characterized by two key abnormalities: amyloid plaques and neurofibrillary 

tangles. Apolipoprotein E (ApoE) is a lipid transport protein that plays a central role in the pathogenesis of 

neurodegeneration in Alzheimer’s disease. [PMID: 14657206] There is also evidence linking Reelin with 

neurodegeneration through binding of ApoE receptors and as a mediator of Tau hyperphosphorylation. 

[PMID: 15583703] 


• 160kDa Neurofilament Medium 

• Amyloid beta precursor protein 

• ApoE 

• ApoE4 

• ApoER2 

ApoE4 (4E4) Antibody 

NBP1-49529 

Western blot 

analysis in 

concentrated 

supernatants of 

CHO cells using 

NBP1-49529. 

Species: Hu 

Applications: WB, ELISA, IP 


GAPDH Antibody (1D4) NB300-221 


Sample Tested: Human Hepatoblastoma 


Additional Comments: The cultured cells 

were harvested, washed and lysed. Extracts 

were stored at -20C prior to analysis 

• Presenilin 1 

• Presenilin 2 

• Reelin 

• Tau 

ApoER2 Antibody 

NB100-2216 

Species: Hu, Mu, Ch 


Western blot 

analysis on 

mouse brain 

membrane using 

NB100-2216. 

GAPDH Antibody (NB300-322) 


Sample Tested: PC3 Whole Cell Lysate 

(Human prostate cancer cell) 


160kDa Neurofilament Medium 

(3H11) Antibody 

NB300-134 


analysis of adult 

neural cells using 

NB300-134. 

Species: Hu, Mu, Av, Ma 


GAPDH (2D4A7) Antibody 

NB300-328 


analysis in 

HeLa cells using 

NB300-328. 


Applications: WB, ELISA, ICC, IF, IHC-P 

GAPDH Antibody (2D4A7) NB300-328 


Sample Tested: HaCaT whole cell lysate 

Sample Pretreatment: UV exposure 



[160kDa Neurofilament Medium Antibody NB300-133] Ziv-Polat O, Skaat H, Shahar A, Margel S. Novel 

magnetic fibrin hydrogel scaffolds containing thrombin and growth factors conjugated iron oxide nanoparticles 

for tissue engineering. Int J Nanomedicine. 2012;7:1259-74. [PMID: 22419873] 

[ApoE Antibody NB100-2040] Terwel D, Steffensen KR, Verghese PB, et al. Critical Role of Astroglial 

Apolipoprotein E and Liver X Receptor alpha Expression for Microglial Abeta Phagocytosis. J Neurosci. 2011 

May 11;31(19):7049-59. [PMID: 21562267] 

[ApoE (WUE-4) Antibody NB110-60531] Lee CY, Tse W, Smith JD, Landreth GE. Apolipoprotein E Promotes 

ß-Amyloid Trafficking and Degradation by Modulating Microglial Cholesterol Levels. J Biol Chem. 2012 Jan 

13;287(3):2032-44. Epub 2011 Nov 30. PubMed [PMID: 22130662]. 

[GAPDH (1D4) Antibody NB300-221] Hoeffer CA, Sanchez E, Hagerman RJ, Mu Y, Nguyen DV, Wong H, 

Whelan AM, Zukin RS, Klann E, Tassone F. Altered mTOR signaling and enhanced CYFIP2 expression levels in 

subjects with fragile X syndrome. Genes Brain Behav. 2012 Jan 23. [PMID: 22268788] 

[GAPDH Antibody NB300-327] Wang M-E, Chen Y-C, Chen I-S, et al. Curcumin protects against 

thioacetamide-induced hepatic fibrosis by attenuating the inflammatory response and inducing apoptosis of 

damaged hepatocytes. The Journal of Nutritional Biochemistry. 2012 Jan 3. [PMID: 22221674] 

18

19 

Parkinson’s Disease 

Parkinson’s disease is a motor system disorder that results from a loss of dopamine-producing neurons. 

Protein aggregates called Lewy bodies develop inside neural cells and displace other cellular contents. 

Symptoms of the disorder include trembling of the extremities and face, stiffness of movement and impaired 

balance and coordination. Several genes have been implicated in Parkinson’s disease. These include PARK2, 

PARK7, PINK1, LRRK2, SNCA, GBA, SNCAIP, and UCHL1. Mutations these genes have been linked to increased 

incidence of the disorder. 


• alpha-Synuclein 

• CASK 

• Caspase 1 

• Caspase 8 

• CD73 

• Cullin 1 

• Cyclin E 

• DARPP32 

• DORFIN 

• Drebrin 

• GBA 

• Glutamate Dehydrogenase 

• GNB3 

• Hsp70 

• LRRK2 

• Park7(DJ-1) 

Hsp70 Antibody 

NBP1-77455 

Species: Hu 




xenograft kidney 

cancer using 

NBP1-77455. 

SIAH2 (24E6H3) Antibody 

NB110-88113 


analysis in ovarian 

carcinoma 

(OVCR3) cells using 

NB110-88113. 

Species: Hu, Dr, Po 

Applications: FACS, ICC, IF, IHC-Fr, IHC-P 

• Parkin 

• PINK1 

• Proteasome 26S S5 

• Rhodopsin 

• Septin-5 

• SIAH1 

• SIAH1/2 

• SIAH2 

• Synphilin-1 

• Tubulin alpha 

• Tubulin beta 

• Ube2G2 

• Ube2L3 

• Ube2L6 

• UCHL1 

LRRK2 Antibody 

NB300-268 


analysis of 

brain using 

NB300-268. 

Species: Hu, Mu, Bv 


Tubulin (YL1/2) Antibody 

NB600-506 


analysis on human 

breast cancer using 

NB600-506. 

Species: Hu, Mu, Rt, Av, Ma, Ye 

Applications: WB, ELISA, ICC, IF, 

IHC-Fr, IHC-P, IP, RIA 

alpha-Synuclein (24.8) [Nitrate Tyr123, 

Nitrate Tyr133] Antibody 

NBP1-26380 

Western blot analysis 

of (A) Nitrated alpha- 

Synuclein protein 

and (B) non-nitrated 

alpha-Synuclein 

protein using 

NBP1-26380. 

Species: Hu 


Caspase 8 (FLICE 4-1-20) Antibody 

NB500-208 

Western blot 

analysis of 

HEK293 cell 

extract using 

NB500-208 

Species: Hu 


Park7(DJ-1) Antibody 

NB300-270 


analysis in 

human cortex 


Species: Hu, Mu, Rt, Bv, Ch, SyHa, Ze 

Applications: WB, ICC, IF, In vitro, IP 

UCHL1 Antibody 

NB300-675 


analysis of 

neurons and their 

cell processes using 

NB300-675. 

Species: Hu, Mu, Rt, Bv, Eq, GP, Mk, Po 

Applications: WB, IHC-P


alpha Tubulin (DM1A) Antibody 

(100-690) 


Sample Tested: Cell lysate 


Beta Tubulin Antibody (NB600-936) 


Sample Tested: Hippocampal Primary 

Culture 


Park7(DJ-1) Antibody (NB300-270) 


Sample Tested: HeLa whole cell lysate, 

mouse brain 


Other Species: Mouse 

Pub Med ID: 21645620 


alpha Tubulin (DM1A) Antibody 

(100-690) 


Sample Tested: Mouse lung tissue 

Sample Pretreatment: 95 C boiling 


GBA Antibody (H00002629-B01P) 

Application: IP 

Sample Tested: Cell lysate 


PINK1 Antibody (BC100-494) 


Sample Tested: HeLa whole cell, mito 

extract 


Sample Pretreatment: CCCP 


Beta Tubulin Antibody (NB600-936) 


Sample Tested: Chicken cell line 

Species: Chicken 

Hsp70 Antibody (13D3) (NB120-2788) 


Sample Tested: HEK293 cell lysate 


UCHL1 Antibody (NB100-65827) 

Application: Immunohistochemistry-Paraffin 

Sample Tested: Brain tissue 


[alpha-Synuclein (24.8) [Nitrate Tyr123, Nitrate Tyr133] Antibody NBP1-26380] Huang Z, Xu Z, Wu Y, Zhou Y. 

Determining nuclear localization of alpha-synuclein in mouse brains. Neuroscience. 2011 Oct 19. 

[PMID: 22033456] 

[alpha Tubulin (DM1A) Antibody NB100-690] Kadiu I, Gendelman HE. Human Immunodeficiency Virus type 1 

Endocytic Trafficking Through Macrophage Bridging Conduits Facilitates Spread of Infection. J Neuroimmune 

Pharmacol. 2011 Jul 26. [PMID: 21789505] 

[Caspase 8 Antibody NB110-56116] Harcourt JL, Caidi H, Anderson LJ, Haynes LM. Evaluation of the Calu-3 

cell line as a model of in vitro respiratory syncytial virus infection. J Virol Methods. 2011 Jun;174(1-2):144-9. 

Epub 2011 Mar 31. 

[DARPP32 [p Thr34] Antibody NBP1-60812] Sarantis K, Antoniou K, Matsokis N, Angelatou F. Exposure to novel 

environment is characterized by an interaction of D1/NMDA receptors underlined by phosphorylation of the 

NMDA and AMPA receptor subunits and activation of ERK1/2 signaling, leading to epigenetic changes and gene 

expression in rat hippocampus. Neurochemistry International. 2011 Nov 7. [PMID: 22080157] 

[Drebrin (M2F6) Antibody NB100-1951] Chen Q, Prior M, Dargusch R, et al. A novel neurotrophic drug for 

cognitive enhancement and Alzheimer’s disease. PLoS ONE. 2011 6(12). [PMID: 22194796] 

[Hsp70 interacting protein HIP (2G6) Antibody NB120-2813] Barker BL, Benovic JL. G protein-coupled 

receptor kinase 5 phosphorylation of hip regulates internalization of the chemokine receptor CXCR4. 

Biochemistry. 2011 Aug 16;50(32):6933-41. [PMID: 21728385] 

[LRRK2 Antibody NB300-954] Sharma S, Bandopadhyay R, Lashley T, et al. LRRK2 expression in idiopathic and 

G2019S positive Parkinson’s disease subjects: A morphological and quantitative study. Neuropathol Appl 

Neurobiol. 2011 Jun 23. [PMID: 21696411] 

[Park7 (DJ-1) Antibody NB300-270] Usami Y, Hatano T, Imai S, et al. DJ-1 associates with synaptic membranes. 

Neurobiol Dis. 2011 May 30. [PMID: 21645620] 

[PINK1 Antibody BC100-494] Meissner C, Lorenz H, Weihofen A, et al. The mitochondrial 

intramembrane protease PARL cleaves human Pink1 to regulate Pink1 trafficking. J. Neurochem. 2011 Jun; 

117(5):856-67. [PMID 21426348] 

[PINK1 Antibody BC100-494] Qi Z, Yang W, Liu Y, Cui T, Gao H, Duan C, Lu L, Zhao C, Zhao H, Yang H. Loss 

of PINK1 function decreases PP2A activity and promotes autophagy in dopaminergic cells and a murine model. 

Neurochem Int. 2011 Oct;59(5):572-81. [PMID: 21672589] 

[UCHL1 (BH7) Antibody NB110-58869] Zhang M, Deng Y, Luo Y, et al. Control of BACE1 degradation and APP 

processing by ubiquitin carboxyl-terminal hydrolase L1. Journal of Neurochemistry. 2011 Dec 30. 

[PMID: 22212137] 

20

Huntington’s Disease 

Huntington’s disease (HD) is a neurodegenerative disorder caused by an expanding polyglutamine repeat in the 

huntingtin gene. HD is a mid-life onset autosomal dominant neurodegenerative disease that is characterized by 

psychiatric disorders, dementia, and involuntary movements (chorea), leading to death in 10-20 years. The HD 

gene product is widely expressed in human tissues, with the highest level of expression in the brain. 


• BDNF 

• HOXA13 

• Caspase 3 • Huntingtin 

• Choline • LAMC2 

Acetyltransferase 

• GM-CSF 

• HIP1 

• Somatostatin 

Huntingtin Antibody 

NBP1-03377 


analysis on 1 

day old mouse 

cortical cell using 

NBP1-03377. 


Applications: WB, IF, IHC-Fr, IHC-P 


Caspase 3 Antibody (CPP32 4-1-18) 

(NB500-210) 

Application: Western Blot 

Sample Tested: Human Hepatoblastoma 

Additional comments: The cultured cells 

were harvested, washed and lysed. Extracts 

were stored at -20C prior to analysis 


Caspase 3 (CPP32 4-1-18) Antibody 

NB500-210 


analysis of 

epithelial cells of the 

tongue base using 

NB500-210. 

Species: Hu, Rt 

Applications: WB, IHC 

Huntingtin Antibody 

NBP1-89710 



cell line U-2 OS 

showing positivity in 

nucleus using 

NBP1-89710. 

Species: Hu 

Applications: IF, IHC-P 

Caspase 3 Antibody (CPP32 4-1-18) 

(NB500-210) 


Sample Tested: Human 


Somatostatin Antibody 

NBP1-78329 


analysis of 

rat hypothalamus 


Species: Hu, Mu, Rt, Am, Fi 

Applications: IF, IHC-Fr, IHC-P 

Choline Acetyltransferase Antibody 

(NB100-1615) 

Application: Immunohistochemistry-Paraffin 

Sample Tested: Mouse brain 


Additional comments: : I recommend this 

product for any IHC-related stains. 


[Active Cleaved Caspase 3 Antibody NB600-1235] Jee D, Lee WK. Inhibitory Effect of intravitreal Injection of 

Bevacizumab on Nerve Growth Factor. Current Eye Research. 2011 Oct 31. [PMID: 22040304] 

[Caspase 3 (CPP32 4-1-18) Antibody NB500-210] Fuzio P, Ditonno P, Rutigliano M, et al. Regulation of TGF-1 

expression by Androgen Deprivation Therapy of prostate cancer. Cancer Letters. 2012 28;318(2):135-144. 

[PMID: 22269108] 

[Caspase 3 (CPP32 4-1-18) Antibody NB500-210] Hsu L-C, Hsu Y-W, Liang Y-H, et al. Induction of Apoptosis 

in Human Breast Adenocarcinoma Cells MCF-7 by Monapurpyridine A, a New Azaphilone Derivative from 

Monascus purpureus NTU 568. Molecules. 2012 17(1):664-673. [PMID: 22237681] 

[Choline Acetyltransferase Antibody NBP1-30052] Sciamanna G, Tassone A, Martella G, et al. Developmental 

Profile of the Aberrant Dopamine D2 Receptor Response in Striatal Cholinergic Interneurons in DYT1 Dystonia. 

PLoS ONE. 2011 6(9). [PMID: 21912682] 

[Somatostatin Receptor 2 Antibody NB300-157] Li F, Ryu BY, Krueger RL, et al. Targeted entry via somatostatin 

receptors using a novel modified retrovirus glycoprotein that delivers genes at levels comparable to wild type 

viral glycoproteins. Journal of Virology. 2011 Oct 19. [PMID: 22013043] 

21 

HIP1 (1B11) Antibody 

NB300-204 


Applications: WB, IP 

Western 

blot analysis 

on HeLa 

whole cell 

extracts using 

NB300-204.

Multiple Sclerosis 

MS is an autoimmune disease caused by damage to the fatty myelin sheaths around the axons of the brain and 

spinal cord. Damage is caused by inflammation and results in nerve damage and slow or absent nerve signals. 

Susceptibility to MS is linked to genes in the Major Histocompatibility Complex and to T cell response. Disease 

activation biomarkers include interleukin-6, nitric oxide, nitric oxide synthase, osteopontin, and fetuin-A. 


• CCL3 

• CCL4 

• CCR1 

• CCR5 

• CXCL9 

• CXCL10 

• CXCL11 

• CXCR3 

• Fetuin 

• HLA 

• IL-6 

• NOA1 

• Osteopontin 

• TNF alpha 

• TNF beta 

IL6 (6D9A1,6C12B1) Antibody 

NBP1-47355 


analysis of 

lung cancer tumor 


Species: Hu 

Applications: WB, ELISA 

Stroke, Epilepsy & Traumatic Brain Injury 

Osteopontin (1B20) Antibody 

NB110-89062 


analysis on 

human lung 

adenocarcinoma 

using NB110-89062. 

Species: Hu, Rt, Rb 

Applications: WB, ICC, IHC-P, IP 

Ischemic episodes, TBI and epilepsy typically result in necrotic cell death at the injury site as well as programmed 

cell death that is controlled via apoptotic cascades in the injured area. Specifically, the mitochondrial-mediated 

apoptotic pathways as well as the PI3K/AKT pathway been implicated in cell death after brain trauma. New 

research aims to reduce apoptosis of cells in the penumbral region after brain injury as means of preserving 

greater neuronal function. [PMIDs: 12684068 & 15662830] 


• AIF 

• CARD 

• DEDD 

• FADD 

• Fas Ligand 

• JNK 

• MAPK 

• MEK2 

• MEKK4 

• MMP9 

• RAIDD 

• RIP1 

• TNF-R1 

• TRADD 

CCR1 Antibody 

NB100-702 

CARD12 Antibody 

NBP1-78979 



JNK1 Antibody 

NB100-1925 


analysis of 

human tonsil 


Species: Hu 

Applications: WB, ELISA, IHC-P 


analysis in HepG2 


(green) using 

NBP1-78979. 

Species: Ce 

Applications: WB, ELISA, IHC-P 

Western blot 

analysis in 

JNK-1 overexpression 

lysates using 

NB100-1925. 

CCR5 Antibody 

NB100-531 


analysis in HeLa 


(green) using 

NB100-531. 

Species: Hu, Mk 

Applications: ELISA, FACS, Func, ICC, In vitro 

Fas Ligand (NOK-1) Antibody 

NB100-77833 

Flow cytometric 

analysis of 

transfected cells 

stained with 

purified NOK-1 using 

NB100-77833. 

Species: Hu 

Applications: FACS, ICC, IF, IP 

MAP2K1IP1/MAPKSP1 Antibody 

NBP1-50631 


analysis in 

mouse lung 




22

23 

Neuronal Markers 

Novus offers a complete line of neuronal marker antibodies that have been validated across multiple applications 

and species. 

Cell Type Antibody Cell Type Antibody 

Astrocyte ABCA1 

Neurons Acetylcholinesterase 

Astrocyte Actin Alpha 2 

Smooth Muscle 

Astrocyte GFAP 

Astrocyte SLC1A3 

Astrocytes Survivin 

Glial Cells SOX2 

Glial Cells Vimentin 

Microglia CD11 

Microglia Ferritin 

Neural Stem Cells DACH1 

Neural Stem Cells GFAP 

Neural Stem Cells HES1 

Neural Stem Cells ISL1 

Neural Stem Cells Ki67 

Neural Stem Cells Musashi-1 

Neural Stem Cells Nestin 

Neural Stem Cells Pax2 



Neural Stem Cells PLAGL1 

Neural Stem Cells PLZF 

Neural Stem Cells REST 

Neural Stem Cells SOX9 

Neural Stem Cells Vimentin 

SLC1A3 Antibody (NBP1-20135) 


Sample Tested: RCC4 Whole cell lysate 

Survivin [p Thr34] Antibody 

(NB500-236) 


Sample Tested: Cancer cells 


Neurons Bag 1 

Neurons Bcl2 

Neurons beta Tubulin 

Neurons Calretinin 

Neurons c-Fos 

Neurons Choline Acetyltransferase 

Neurons ELF 

Neurons HSV1 

Neurons MAP2 

Neurons Nestin 

Neurons Neurofilament Heavy 

Neurons Neurofilament Light 

Neurons Neurofilament Medium 

Neurons NQO1 

Neurons RBFOX3/NeuN 

Neurons Synapsin 

Neurons UCHL1 

Oligodendrocytes CNPase 

Oligodendrocytes MAP4 

Oligodendrocytes MOG 

Oligodendrocytes Nestin 

Oligodendrocytes OLIG2 

Schwann Cells Laminin 

Schwann Cells Ran 

Tubulin Beta 3 Antibody 

(NB600-1018) 

Application: ICC 


Differentiated Neural Cell 


200 kDa Neurofilament Heavy 

Antibody NF-01 (NB500-416) 


Sample Tested: nerve tissue from mouse 

spinal cord 

ABCA1 Antibody (3A1.891.3) 

(NB400-164) 


Sample Tested: Brain microvessel total 

proteins 


c-Fos Antibody (NB100-91772) 



Sample Pretreatment: Citrate buffer 

Ki67 Antibody (NB110-89717) 

Application: FACS 

Sample Tested: Mouse bone 

marrow cells 

Ki67 Antibody (NB500-170) 


Sample Tested: Whole cell lysate 


ABCA1 Antibody 

(NB400-105) 

Application: Western bBlot 



Survivin Antibody (NB500-201) 


Sample Tested: Oswald 1771 

Abrams D17 Cancer Cell Lines 

Sample Pretreatment: 7-15 ug

68kDa Neurofilament Light (DA2) 

Antibody 

NB300-132 


analysis of 

neurons in 

culture using 

NB300-132. 

Species: Hu, Av, Ma 

Applications: WB, IF, IHC 

beta Tubulin Antibody 

NB600-936 


analysis of 

HeLa cells using 

NB600-936. 

Species: Hu, Mu, Rt, Ch, Mk, Po, Xp, Ze 

Applications: WB, ICC, IF 

Nestin (10C2) Antibody 

NB300-266 


analysis in PC-3 

cells using 

NB300-266. 

Species: Hu 

Applications: WB, FACS, ICC, IF, IHC-Fr, IHC-P 


200kDa Neurofilament Heavy 

Antibody 

NB300-135 


analysis of 

rat spinal cord 


Species: Hu, Mu, Rt, Ma, Mk 

Applications: WB, ELISA, IF, IHC-Fr, IHC-P 

CD11b Antibody 

NB110-89474 

Survivin Antibody 

NB500-201 


analysis in 

in human renal 

cancer using 

NB110-89474. 


Applications: WB, FACS, ICC, IF, IHC-P 


analysis of telophase 

in the midbodies of 

two daughter cells 


Species: Hu, Mu, Rt, Ca, Fe 

Applications: WB, ChIP, ICC, IF, IHC-P, IP 

ABCA1 Antibody 

NB400-105 


analysis in 

prostate epithelium 


Species: Hu, Mu, Rt, Ha 

Applications: WB, FACS, ICC, IF, IHC-P, IP 

Ki67 Antibody 

NB500-170 


analysis in 

human 

tonsil using 

NB500-170. 

Species: Hu, Mu, Po 

Applications: ICC, IF, IHC-Fr, IHC-P 

ZNF643 Antibody 

NBP1-92639 

Species: Hu 



analysis of 

human testis using 

NBP1-92639. 

[68kDa Neurofilament Light Antibody NB300-131] Yokoyama K, Tezuka T, Kotani M, et al. NYAP: a phosphoprotein 

family that links PI3K to WAVE1 signalling in neurons. The EMBO Journal. 2011 Sep 23. [PMID: 21946561] 

[ABCA1 (HJ1) Antibody NB100-2068] de Souza Pinto R, Castilho G, Paim BA, et al. Inhibition of Macrophage 

Oxidative Stress Prevents the Reduction of ABCA-1 Transporter Induced by Advanced Glycated Albumin. Lipids. 

2012 Jan 21. [PMID: 22271422] 

[Actin Alpha 2 Smooth Muscle Antibody NB600-531] Saatchi S, Azuma J, Wanchoo N, et al. Three-dimensional 

microstructural changes in murine abdominal aortic aneurysms quantified using immunofluorescent array 

tomography. J Histochem Cytochem. 2012 Feb;60(2):97-109. [PMID: 22140132] 

[CD11b Antibody NB110-89474] Jin H, Li YH, Xu JS, et al. Lipoxin A4 analog attenuates morphine 

antinociceptive tolerance, withdrawal-induced hyperalgesia, and glial reaction and cytokine expression in the spinal 

cord of rat. Neuroscience. April 19; 208;1-10. [PMID: 22366510] 

[CD11c (AP-MAB0814) Antibody NBP1-06651] Dravis C, Henkemeyer M. Ephrin-B reverse signaling controls 

septation events at the embryonic midline through separate tyrosine phosphorylation-independent signaling 

avenues. Dev Biol. 2011 Jul 1;355(1):138-51. [PMID: 21539827] 

[Ferritin Antibody NB600-920] Daba A, Koromilas AE, Pantopoulos K. Alternative ferritin mRNA translation via 

internal initiation. RNA. 2012 Mar;18(3):547-56. [PMID: 22271759] 

[Ki67 Antibody NB500-170] McCaskey SJ, Rondini EA, Langohr IM, Fenton JI. Differential effects of energy 

balance on experimentally-induced colitis. World J Gastroenterol. 2012 Feb 21;18(7):627-36. [PMID: 22363133] 

[SLC1A3 Antibody NB100-1869] Salvatore MF, Davis RW, Arnold JC, Chotibut T. Transient striatal GLT-1 blockade 

increases EAAC1 expression, glutamate reuptake, and decreases tyrosine hydroxylase phosphorylation at ser(19). 

Experimental Neurology. 2012 Jan 17. [PMID: 22285253] 

[Survivin Antibody NB500-201] Francisco R, Pérez-Perarnau A, Cortés C, et al. Histone deacetylase inhibition 

induces apoptosis and autophagy in human neuroblastoma cells. Cancer Letters. 2012 May 1: 318 (1) 42-52. 

[PMID: 22186300] 

[Survivin Antibody (60.11) NB500-238] Schöneberger H, Weiss A, Brill B, et al. The integration of a Stat3 

specific peptide aptamer into the thioredoxin scaffold protein strongly enhances its inhibitory potency. 

Hormone Molecular Biology and Clinical Investigation. 2011 Jun 135(1):1-9. 

24

25 

Antibody Support Products 

Novus offers a variety of products for use in conjunction with our Primary Antibodies. All support products are 

also of the highest quality and are backed by our Novus Guarantee, no hassles, no nonsense. 

Secondary Antibodies, 

Lysates, Peptides, 

Proteins & RNAIs 

Visit www.novusbio.com and 

select your primary antibody of 

interest to see all of the related 

support products. 

Epitope Tags 

Epitope tagging is a powerful 

tool for the detection and 

purification of expressed 

proteins, and Novus Biologicals 

offers a wide range of epitope 

tag specific antibodies for a 

variety of immunological 

applications. 

AbSelect Antibody 

Purification Kits 

Commercially available 

antibodies often contain 

substances (e.g. BSA, glycine, 

tris, azide) that interfere in 

labeling reactions. The AbSelect 

Purification Kit quickly removes 

these contaminants. 

Isotype Controls 

Identify any background signal 

in your FACS experiment with 

our extensive selection of top 

quality isotype control 

antibodies. Now available for 

most species, isotypes, and 

fluorescent conjugates. 

Realize the Many Advantages of Precipitor TM 

• IP in less than 30 minutes with no centrifugation or pipetting 

• Rapid, multi-step automation 

• 96 well plate format 

• Multiplex up to 16 samples 

• Reproducible and consistent results 

• No external device or PC required 

• Affordable Price 

Contact us about a 

two week free trial.* 

precipitor@novusbio.com 

*Applicable in the USA only 

Lightning-Link Antibody 

Labeling Kits 

Lightning-Link is the easiest 

and quickest method available 

for making antibody (protein) 

conjugates, requiring just 30 

seconds hands-on time. 

ELISA Kits & Matched 

Antibody Pairs 

Our complete ELISA kits 

contain all of the components & 

reagents for a successful ELISA. 

Plus, it has never been easier to 

find the right antibody pair for 

your sandwich ELISA. 

Precipitor High Throughput Immunoprecipitation and Purification System 

Automated magnetic bead platform for high-throughput precipitation and purification of proteins.

Technical Support 

Novus Biologicals stands behind all of our products 100%. We have a global team of specialists 

available to help you as well as detailed protocols, illustrated assay guides and video tutorials on our website. 

Our Techincal Support team can be reached at technical@novusbio.com and also on our live chat feature at 

www.novusbio.com. 

Western Blot Protocol Immunocytochemistry Protocol 

Chromatin Immunopreciptation Protocol 

Novus Explorer 

This free bioinformatics 

tool is designed to facilitate 

scientific exploration of 

related genes, diseases and 

pathways based on co-citations. 

For moreinformation visit 

www.novusbio.com/explorer. 

Live Chat 

26

ORDERING 

S 

For research purposes only. 

Prices subject to change. 

Not for use in humans. 

Neuro Catalog H2

NOVUS BIOLOGICALS ANTIBODIES FOR - BioNova

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