Neonatal Unconjugated Hyperbilirubinemia

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Hereditary Spherocytosis Incidence Incidence of 1:5000 Autosomal Autosomal dominant Heterogeneous presentation Fifty Fifty percent present with hemolytic anemia, hyperbilirubinemia, reticulocytosis, and increased erythrocyte osmotic fragility
Infection <strong>Hyperbilirubinemia</strong> <strong>Hyperbilirubinemia</strong> is believed to be secondary to hemolysis Sepsis Sepsis may impair conjugation also leading to increased bilirubin levels
Page 1 and 2: Clinical Case JR, JR, 7 do hispanic
Page 3 and 4: Baby Baby was OK at home, eating we
Page 5 and 6: Work Up CBC CBC - WBC 13.6, H/H 18.
Page 7 and 8: ER course VSS, VSS, baby was jaundi
Page 9 and 10: Neonatal Hyperbilirubinemia
Page 11 and 12: Jaundice A A visible manifestation
Page 13 and 14: WHY DO INFANTS DEVELOP HYPERBILIRUB
Page 15 and 16: Bilirubin Bilirubin is the breakdow
Page 17 and 18: Binding and Transport Unconjugated
Page 19 and 20: Blood Blood flow through the hepati
Page 21: Conjugation Bilirubin Bilirubin dis
Page 25 and 26: Neonatal Hyperbilirubinemia Physiol
Page 27 and 28: Disorders of Production Isoimmuniza
Page 29 and 30: Rh Incompatibility This is a blood
Page 31 and 32: ABO Incompatibility This This is a
Page 33 and 34: Erythrocyte Enzymatic Defects Gluco
Page 35 and 36: RBCs RBCs are unable to activate th
Page 37 and 38: Its Its deficiency leads to decreas
Page 39: Hereditary Elliptocytosis Incidence
Page 43 and 44: Polycythemia The The increase in re
Page 45 and 46: Disorders of Conjugation Crigler Cr
Page 47 and 48: Type Type II There There is various
Page 49 and 50: Pyloric Stenosis 10 10-25% 25% of b
Page 51 and 52: Disorders of Enterohepatic Circulat
Page 53 and 54: Breast Milk Jaundice Occurs Occurs
Page 55 and 56: Sequelae Bilirubin Bilirubin may pe
Page 57 and 58: Long Long term sequelae: Kernicteru
Page 59 and 60: Diagnosis and Management There Ther
Page 61 and 62: Risk Assessment Every Every newborn
Page 63 and 64: Assessment of risk - Major Predisc
Page 65 and 66: Carbon Monoxide The The breakdown o
Page 67 and 68: If: If: When should I do more? Cord
Page 69 and 70: Algorithm for the management of jau
Page 71 and 72: Helpful resources Bili-Aid Bili Aid
Page 73 and 74: Wavelength Wavelength Technique Bil
Page 75 and 76: Positioning Positioning Within With
Page 77 and 78: The The TSB level for discontinuing
Page 79 and 80: Guidelines for exchange transfusion
Page 81 and 82: Exchange Transfusion With With a ex
Page 83 and 84: Management Management of Hyperbilir
Page 85 and 86: Provide parents with written and ve
Page 87: Fanaroff, Fanaroff, Martin. Neonata

Neonatal Unconjugated Hyperbilirubinemia

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