Neonatal Unconjugated Hyperbilirubinemia

Sequelae
Bilirubin Bilirubin may penetrate the brain cell and
cause neuronal dysfunction or death if not
carefully managed
Bilirubin Bilirubin causes staining and necrosis of
neurons in the basal ganglia, hippocampal
cortex, subthalamic nuclei, and cerebellum
which is followed by gliosis
50%of 50%of patients with kernicterus die