PBT profiling of pre-registered substances – by QSAR ... - REACh
PBT profiling of pre-registered substances – by QSAR ... - REACh
PBT profiling of pre-registered substances – by QSAR ... - REACh
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European Commission<br />
Directorates-General<br />
Directorates or Institutes<br />
Units<br />
Europeans Commissions<br />
Joint Research Centre<br />
Molecular Biology<br />
In Vitro Methods<br />
Nanobiosciences<br />
Chemical Assessment &<br />
Testing<br />
Systems Toxicology<br />
JRC<br />
Computational Toxicology<br />
Genetically Modified Organisms<br />
Alternative Methods & ECVAM<br />
Nanotechnology<br />
Policy<br />
Health and Environment Areas<br />
Consumer Products & Nutrition<br />
Overall aim: to promote the development, assessment, acceptance<br />
and implementation <strong>of</strong> computer-based methods potentially suitable<br />
for the regulatory assessment <strong>of</strong> chemicals<br />
Applications: REACH, Water Framework Directive, Cosmetics<br />
Directive, Biocides Directive, Plant Protection Products Directive<br />
Main approaches: SAR, <strong>QSAR</strong>, molecular modelling, ranking<br />
Computational methods provide information for use in hazard and<br />
risk assessment → “non-testing” or alternative methods<br />
http://ecb.jrc.ec.europa.eu/qsar/<br />
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