IPV BSL-3/polio containment guidelines (Feb 2003) - World Health ...

Primary containment: A system of containment, usually a biological safety cabinet or
closed container, which prevents the escape of a biological agent into the immediate
working environment.
Respirator: A respiratory protective device with an integral perimeter seal, valves and
specialized filtration, used to protect the wearer from toxic fumes or particulates.
Risk analysis: A formalized documented process for analysing risks.
Secondary containment: A system of containment, usually involving specialized air
handling, airlocks, and secure operating procedures, which prevents the escape of a
biological agent into the external environment or into other working areas.
Sharps: Devices used in the laboratory, which are capable of cutting or puncturing skin
(e.g. needles, scissors, glass etc.)
Sterilization: A process that destroys and/or removes all classes of micro-organisms and
their spores.
Validation: The documented act of proving that any procedure, process, equipment,
material activity, or system actually leads to the expected results.
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Adopted by the 53 rd meeting of the WHO Expert Committee on Biological Standardization, 17-21 February 2003. A definitive
version of this document, which will differ from this version in editorial but not scientific detail, will be published in the WHO
Technical Report Series.