Pemphigus and BMZ diseases in people: presentations and ...
Pemphigus and BMZ diseases in people: presentations and ...
Pemphigus and BMZ diseases in people: presentations and ...
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• Subepidermal blister at level of lam<strong>in</strong>a lucida<br />
• Neutrophilic microabscesses <strong>in</strong> dermal papillae<br />
IF - see table 1<br />
Management<br />
• Dapsone or sulfapyrid<strong>in</strong>e<br />
• Gluten-free diet<br />
• Avoid iod<strong>in</strong>e <strong>and</strong> NSAIDs<br />
Course <strong>and</strong> prognosis<br />
• Persists <strong>in</strong>def<strong>in</strong>itely<br />
• Waxes <strong>and</strong> wanes<br />
References<br />
1. Fassihi H, Wong T, Wessagowit V et al. Target prote<strong>in</strong>s <strong>in</strong> <strong>in</strong>herited <strong>and</strong> acquired blister<strong>in</strong>g sk<strong>in</strong> disorders. Cl<strong>in</strong>ical<br />
<strong>and</strong> Experimental Dermatology 2006; 31: 252-259.<br />
2. Herne KL, Jordon RE, Hsu S. Autoimmune bullous <strong>diseases</strong>. In: Ali A ed. Dermatology: A Pictorial Review. Ch<strong>in</strong>a:<br />
The McGraw-Hill Companies, 2007: 139-151.<br />
3. Saha M, Harman K, Mortimer NJ et al.<strong>Pemphigus</strong> vulgaris <strong>in</strong> white Europeans is l<strong>in</strong>ked with HLA Class II Allele<br />
HLA DRB1*1454 but Not DRB1*1401 Journal of Investigative Dermatology 2010; 130: 311–314.<br />
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