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Pemphigus and BMZ diseases in people: presentations and ...

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• Subepidermal blister at level of lam<strong>in</strong>a lucida<br />

• Neutrophilic microabscesses <strong>in</strong> dermal papillae<br />

IF - see table 1<br />

Management<br />

• Dapsone or sulfapyrid<strong>in</strong>e<br />

• Gluten-free diet<br />

• Avoid iod<strong>in</strong>e <strong>and</strong> NSAIDs<br />

Course <strong>and</strong> prognosis<br />

• Persists <strong>in</strong>def<strong>in</strong>itely<br />

• Waxes <strong>and</strong> wanes<br />

References<br />

1. Fassihi H, Wong T, Wessagowit V et al. Target prote<strong>in</strong>s <strong>in</strong> <strong>in</strong>herited <strong>and</strong> acquired blister<strong>in</strong>g sk<strong>in</strong> disorders. Cl<strong>in</strong>ical<br />

<strong>and</strong> Experimental Dermatology 2006; 31: 252-259.<br />

2. Herne KL, Jordon RE, Hsu S. Autoimmune bullous <strong>diseases</strong>. In: Ali A ed. Dermatology: A Pictorial Review. Ch<strong>in</strong>a:<br />

The McGraw-Hill Companies, 2007: 139-151.<br />

3. Saha M, Harman K, Mortimer NJ et al.<strong>Pemphigus</strong> vulgaris <strong>in</strong> white Europeans is l<strong>in</strong>ked with HLA Class II Allele<br />

HLA DRB1*1454 but Not DRB1*1401 Journal of Investigative Dermatology 2010; 130: 311–314.<br />

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