ROYAL MEDICAL AND CHIRURGICAL SOCIETY.
ROYAL MEDICAL AND CHIRURGICAL SOCIETY.
ROYAL MEDICAL AND CHIRURGICAL SOCIETY.
Create successful ePaper yourself
Turn your PDF publications into a flip-book with our unique Google optimized e-Paper software.
1100 X.,Bain=] <strong>ROYAL</strong> <strong>MEDICAL</strong> <strong>AND</strong> <strong>CHIRURGICAL</strong> <strong>SOCIETY</strong>. [Nov. 18, 1893.<br />
easily be put on one side, on the grounds that the injury<br />
might have been due to an epileptic seizure, although, of<br />
course, the suggestion that the injury was not the cause of<br />
the disease may be correct. Anyhow, it was impossible to<br />
localise the seat of injury or any special centre of disease,<br />
which might have made an operation advisable. In fact the<br />
whole history of the case suggests a widespread lesion.<br />
Hi8tor.-B. L. P., male, aged 13, was admitted on October<br />
3rd, 1892. Two or three years previous to admission he was<br />
knocked down by a horse and trap, which went over him,<br />
the shaft striking him on the back of the head. He was<br />
stunned and remained unconscious for about three hours.<br />
Before the accident he was a bright intelligent lad, but was<br />
never the same again. At first his home lessons caused him<br />
difficulty; these were diminished, but in time he became<br />
quite unable to learn anything. Fourteen months before<br />
admission he had a kind of seizure in which he lost power on<br />
the left side. The weakness remained, and from that time<br />
he gradually got worse, and finally became unmanageable.<br />
He shouted and screamed without cause, tried to run away,<br />
and became dirty in habits and violent in conduct.<br />
On Admiwsion.-He was a thin, fair-haired boy. Eyes grey;<br />
pupils equal and sluggish. Power of left leg diminished.<br />
No disease discovered in abdominal or thoracic viscera.<br />
Mentally was quite unable to appreciate his surroundings or<br />
to understand what was said to him.<br />
After-HYistory.-After admission, he was noted to be very<br />
weak on his legs, and fell about the ward. He was noisy and<br />
troublesome, and dirty in habits. On November 18th, the<br />
following note was made: Left pupil larger than right: knee<br />
jerks intensely exaggerated; ankle clonus not obtained; gait<br />
spastic; would open his mouth, and bite at any object held<br />
in front of him; tongue tremulous, protruded straight;<br />
speech hesitating; holds his hands in front of him all day,<br />
and rubs them together, at the same time talking unintelligibly<br />
if spoken to, he echoes the last part of the sentence.<br />
On November 26th, he had a seizure, in which he did not<br />
appear to lose consciousness. Twitching of the right eye<br />
and hand were first noticed, and later the muscles of the<br />
right side of the face were involved. After the attack, the<br />
right leg was found to be weak, so that he fell over on trying<br />
to walk. After the seizure, he fell asleep, as after an ordinary<br />
epileptic fit. He then gradually became thinner and<br />
weaker, so that in February it was found necessary to keep<br />
him in bed. Since then he has had two other seizures, one<br />
involving the left side and the other the right. No marked<br />
alteration has taken place.<br />
At the present time he lies in bed all day, with his knees<br />
drawn up touching his chin, takes no notice of his surroundings,<br />
and passes a purely vegetative existence; takes food<br />
when it is offered him, but also opens his mouth to bite at<br />
anything else that is placed in front of it. Exercises no control<br />
over his emunctories. Muscles atrophied, but irritable.<br />
Knee jerks cannot be obtained. Tdche c6r6brale well<br />
marked. Mumbles incoherently, and is often noisy at night.<br />
Is much emaciated, in spite of a voracious appetite well<br />
satisfied. Has never suffered from vomiting, or had optic<br />
neuritis.<br />
REPORTS OF SOCIETIES,<br />
<strong>ROYAL</strong> <strong>MEDICAL</strong> <strong>AND</strong> <strong>CHIRURGICAL</strong> <strong>SOCIETY</strong>.<br />
WILLIAM CHURCH, M.D., F.R.C.P., Vice-President, in the<br />
Chair.<br />
Tuesday, November 14th, 1893.<br />
DEATH OF SiR <strong>AND</strong>REW CLARK.<br />
DR. CHURCH, at the opening of the proceedings, refelred in<br />
a brief but most admirable speech to the great loss which the<br />
Society had suffered by the loss of its President, Sir Andrew<br />
Clark. Subsequently a resolution of condolence was adopted.<br />
[A full report of Dr. Church's speech and of the text of the<br />
resolution will be found at page 1111.]<br />
OPERATIONS WITHOUT ANAESTHESIA.<br />
Mr. C. B. KEETLEY, who read this paper, said that after the<br />
discovery of surgical anaesthesia certain causes led to its<br />
abuse: (1) its dangers were not at first realised; (2) surgeons<br />
and the public forgot what could be done without it. Nevertheless,<br />
local ancesthesia received a hearty welcome; but its<br />
applicability was, of course, strictly limited, especially since<br />
it had been known that cocaine had its dangers. An alarming<br />
case in the author's own practice led him to perform<br />
various operations under a nominal cocaine aneesthesia, and<br />
experience then acquired gave him an insight into what could<br />
be done in operative surgery without, anaesthesia. But he<br />
first learned the full possibilities in this direction by the<br />
necessity of operating on certain thyroid tumours without<br />
anaesthesia. A case was shown in which the operation lasted<br />
over three hours. The sensitiveness of different structures<br />
was then compared. Although a tissue might be itself insensitive,<br />
its connections might make it practically very<br />
sensitive. If the question of the sensitiveness of the peritoneum<br />
was treated from a practical point of view, that of the<br />
parts immediately beneath it must be considered at the same<br />
time. The amount of pain evoked depended greatly on the<br />
instrument used. Could any rules useful in practical<br />
surgery be deduced from the facts passed in review?<br />
General anaesthesia should, as a rule, be avoided in cases of-<br />
(1) Strangulated hernia in old and exhausted subjects; (2)<br />
colotomy and colectomy in similar subjects, when the course<br />
of operation could be foreseen and planned beforehand; (3)<br />
mere tapping, aspirating, sounding, or even laparotomy by<br />
small incision for exploring, combined perhaps with evacuation<br />
of fluid (or even of simple non-adherent cysts ?). On the<br />
other hand, general anaesthesia was decidedly indicated in<br />
operations on the trunk and head, the full extent of which<br />
could not be foreseen, and for such extensive operations as<br />
major amputations, excisions, osteotomies, and trephinings.<br />
Nitrous oxide was available for many cas&s in which it was<br />
now usual to employ ether or chloroform, especially for<br />
special operations which the surgeon concerned was much<br />
practised in; for simple incisions, however long; for encapsuled<br />
tumours, however large, if superficial; and for refracturing<br />
mal-united bones. It was exceedingly economical<br />
of time, a most important consideration in these days.<br />
The use of cocaine was. limited by the dangerous susceptibility<br />
of some individuals to any but very small doses.<br />
Nevertheless, it was available for many thousands of minor<br />
operations for which patients were every year exposed to the<br />
risks, discomforts, and expense of chloroform. Many cases in<br />
which cocaine was supposed to have acted well were really instances<br />
of nominal or imaginary anaesthesia, and especially<br />
when the part operated on was the abdomen. Such, also,<br />
probably were many cases of hypnotic ansesthesia. The paper<br />
concluded with critical remarks on certain questions relating<br />
to the subject.<br />
Mr. POWER noticed that the author had not touched upon<br />
the use of anaesthetics with reference to affections of the eyes.<br />
Before the advent of chloroform, such an operation as enucleation<br />
of the globe was occasionally a very serious business.<br />
Now, except for the more serious operations, as enucleation<br />
or abscission, chloroform wvas not even necessary, a 5 per cent.<br />
or 10 per cent. solution of cocaine being quite sufficient to<br />
render such operations as iridectomy perfectly painless.<br />
Dentists were the people who came most directly in contact<br />
with acute pain, and Mr. Power mentioned the exhaustion<br />
and depression which followed the abstraction of a large<br />
molar. Guthrie, in his commentaries on the war, alluded to<br />
a wounded soldier who ran with his intestines in his hands<br />
to a farmhouse, where a milkmaid had washed them in warm<br />
milk, and replaced them in the abdomen, and the man finally<br />
recovered. Mr. Power had been surprised that once, when<br />
suffering from pleurisy, the passage of a trocar through his<br />
chest wall had been quite painless.<br />
Dr. KENNETH MCLEOD thought that the option of the<br />
patient should always be considered. He mentioned that<br />
alcoholic intoxication produced complete aniesthesia. It was<br />
as important to relieve the anticipation of pain as the actual<br />
pain djring the operation.<br />
Mr. GEORGE EASTEs referred to the enormous variation in<br />
relation to pain of different individuals, and quoted a case<br />
in his father's practice in which a labourer had had a toe<br />
amputated without making a face, and he had himself that<br />
morning given an aneesthetic to a lady for the removal<br />
of piles, and, although the conjunctivse were quite insensitive,<br />
she yet had evinced signs of pain at the commence-
Nov. 18, 1893.] CLINICAL <strong>SOCIETY</strong> OF LONDON. ITnuBVLn 1 101<br />
ment of the operation. In reference to puncture of the chest,<br />
a lump of ice previously applied for two or three minutes<br />
deadened sensation sufficiently. It was always necessary to<br />
determine the depth of aneesthesia suitable to any given<br />
patient, and one great value of aneesthesia was to deaden the<br />
menital impression so that the surgeon could go quietly to<br />
work.<br />
Dr. HEWITT considered that Mr. Keetley had done good<br />
service in bringing forward this question. There was no<br />
doubt that general anaesthesia was not so successful in some<br />
classes of cases as in others. He quite agreed that one<br />
should not use a general anaesthetic if local aneesthesia was<br />
sufficient. He himself thought that in some cases of strangulated<br />
hernia in which the patient was very bad, local ansesthesia<br />
was preferable to general. He also thought that in<br />
some cases of tracheotomy for diphtheria, in cases of innominate<br />
aneurysmi with urgent dyspncea, in large goitres<br />
pressing on the trachea in which the patients were suffering<br />
from bronchitis or advanced phthisis, local anmesthetics were<br />
again preferable to general. One must always remember,<br />
however, that this kind of cases constituted but a very small<br />
minority of operations. In all cases where the mental element<br />
came into consideration a general anaesthetic was necessary.<br />
Again, in some pulmonary and pleural conditions,<br />
there was a certain degree of risk in the use of a general<br />
anaTsthetic. He congratulated Mr. Keetley on having been<br />
able to operate for three hours in removal of a thyroid without<br />
any anaesthetic.<br />
Mr. WALTER SPENCER thought that the danger of general<br />
anmesthetics must be chiefly laid to the door of those who<br />
administered chloroform without having had sufficient experience.<br />
He considered that operations about the rectum<br />
could only be undertaken when the patient was under a<br />
general anmesthetic. Although not much used now, one of<br />
the quickest and most satisfactory ways of incising the skin<br />
was by transfixion.<br />
Mr. BALLANCE quite agreed with Mr. Keetley in operating<br />
on the thyroid without a general anaesthetic. In many<br />
cases he felt sure that it was of great advantage to intermit<br />
the administration of a general aneesthetic during operations.<br />
He always felt that a patient was never so near death as when<br />
under profound anesthesia. Still, for all serious operations<br />
lhe was sure that general aneesthesia was of advantage to<br />
both patient and surgeon. In abdominal cases prolonged<br />
anaesthesia was by no means always necessary, and if the<br />
surgeon would get his sutures into place whilst the patient<br />
was unconscious a large part of the operation could be done<br />
without continuing the anaesthetic. He considered that<br />
general anesthetics were absolutely necessary in operations<br />
upon children.<br />
Mr. KEETLEY, in reply, quite agreed that anesthetics<br />
should always be used for children, except for such an<br />
operation as that for imperforate anus in early infancy. He<br />
agreed with Mr. Spencer that transfixion was the best way of<br />
removing non-malignant tumours. He defended the removal<br />
of the goitre without an aneesthetic on the ground that in a<br />
previous case the an.esthetic had been almost impossible to<br />
administer, owing to impending death more than once during<br />
the operation, and it was well known that surgeons who<br />
operated largely on bronchoceles, such as some of the Swiss<br />
surgeons, had discarded the use of anmesthetics. He thanked<br />
Mr. Power for his most interesting remarks on his personal<br />
experience of the times before the introduction of anoesthetics.<br />
THE Russian Government is understood to have expressed<br />
a wish that the Twelfth International Medical Congress, to<br />
be held in 1896, should meet at Moscow. It has promised the<br />
sum of 50,000 roubles towards the expenses of the Congress.<br />
THE NOTIFICATION OF PHTHISIS.-At meetings of the Oldlham<br />
Medical Society on October 24th and November 7th, the<br />
notification of phthisis formed the subject of a prolonged discussion.<br />
The following resolution was carried unanimously:<br />
"That the Society, having had its attention drawn to the infection<br />
of tuberculous diseases and to the great mortality and<br />
injurT to the population arising therefrom, is of opinion that<br />
these diseases should be the subject of voluntary notification<br />
to the sanitairy authority."<br />
7<br />
CLINICAL <strong>SOCIETY</strong> OF LONDON.<br />
JOHN WHITAKER. HULKE, F.R.C.S., F.R.S., President, in the<br />
Chair.<br />
Friday, Noveinber 10th, 1893.<br />
TRAUMATIC ARACHNOID H +EMORRHAGE, WITH SYMPTOMS ON<br />
THE SAME SIDE AS THE LESION.<br />
MR. C. MANSELL MOULLIN read notes of tllis case. T. C., a<br />
stevedore, aged 43, was admitted into the London Hospital<br />
on May 30th in a state of almost complete coma, having been<br />
struck a violent blow on the right side of the head three<br />
hours before by the hook of a swinging crane. He was not<br />
stunned, and continued to work until shortly before admission,<br />
when he suddenly became faint. The muscles of the<br />
right side of the face were paralysed; the right arm and leg<br />
were very rigid, and he could not be made to move them.<br />
The seat of injury was explored, but there was no fracture.<br />
The next day the coma was less, but the paralysis of the faceand<br />
limbs more marked. This continued until the eighth<br />
day, when the coma became much deeper, with intervals of<br />
delirium. The right-sided paralysis remained the same, the<br />
tongue in addition being a0ected. As the patient was sinking<br />
the left side of the brain was explored over the motor<br />
area and found to be uninjured. The day following the<br />
patient died, the temperature rising to 1060 F. At the<br />
necropsy there was no fracture, nor was there anly lhemnorrhage<br />
between the dura and the bone. The arachlnoid space<br />
on the injured side was filled with a coagulum which covered<br />
the surface of the hemisphere, but which could be washed off<br />
with a gentle streani of water, leaving the surface of the<br />
arachnoid uninjured. The source of the hmmorrhage appeared<br />
to be one of the branches of the posterior division of<br />
the middle meningeal. The brain was carefully examined on<br />
both sides, but no sign of contusion or laceration could be<br />
detected. Attention was drawn to the peculiar occurrence<br />
of the haemorrhage, without fracture or aneurysm, and without<br />
any distinct evidence of atheroma, and to the fact that<br />
the symptoms throughout were on the same side as the<br />
injury, neither the face nor the body on the opposite side<br />
having shown the least sign of motor paralysis.<br />
The PRESIDENT, referring to the question of the site of the<br />
lesion, described a similar case. A man stooping down was,<br />
struck on the right temple by a falling ladder. Ile rose<br />
dazed. A bruise formed which disappeared after three or<br />
four days. He had headache and difficulty of walking, and,<br />
ten days afterwards, was brought to the hospital suffering<br />
from right hemiplegia. A medical colleague advised that<br />
he should, on physiological grounds, be trephined on the<br />
side opposite to the injury, but Mr. Hlulke cut down at the<br />
seat of injury and trephined. Here the bone was quite right,<br />
and the dura mater had nothing abnormal external to it.<br />
Upon its being incised some bloody serum escapedl from beneathi<br />
it. He recovered consciousness, and was finally restored<br />
to health. If the operation had been done oIn the<br />
opposite side on physiological grounds the collection of<br />
serum would have been missed and the patient in all probability<br />
have died.<br />
Mr. J. H. DAUBER mentioned a case of right hieiniplegia,<br />
following injury of the right parietal bone. The man was in<br />
a well when a pulley fell on him. For a month after the<br />
accident, however, he kept at work. lie had by that time<br />
an abscess at the site of injury; pus was running from the<br />
wound. Pieces of bone were removed from the wound, but<br />
the patient succumbed. At the post-mortem examination.<br />
meningitis and cerebritis were found, and one piece of bone<br />
was found still embedded in the brain.<br />
Dr. BEEVOR said that most cases of hemiplegia on the sameside<br />
as the lesion were traumatic, and it was difficult in such<br />
cases to localise the lesion exactly. All the weight of physiological<br />
evidence was against the supposition that the right.<br />
half of the brain could regulate the right half of the body.<br />
Dr. HALE WHITE remarked that he knew of one case in<br />
which a surgeon had trephined on the same side as the paralysis,<br />
but had found nothing, and after death the lesion was.<br />
found to be on the other side of the brain. The cortex on.<br />
the other side in Mr. Moullin's case should have been examined<br />
microscopically, to prove that it was uninjured, before<br />
one could, on such evidence, overthrow the teachings of<br />
physiology.
1102 <strong>MEDICAL</strong> JOURNAtl <strong>MEDICAL</strong> <strong>SOCIETY</strong> OF LONDON. [Nov. 18, 1893.<br />
Mr. MANSELL MiOULLIN regretted lie had not made such a<br />
microscopical examination of the other half of the cortex; it<br />
had seemed to him that a large blood clot was sufficient evidence<br />
of the site of the lesion.<br />
DISEASE OF THE CORPORA QUADRIGEMINA.<br />
Dr. FREDERICK TAYLiOR read a report of this case. The<br />
subject was a boy, aged 4, who, four months before admission<br />
into the Evelina Hospital, became ill, would not eat, and had<br />
drooping of the eyelids. Gradually after this lie lost strength.<br />
Fourteen days before admission he began to stagger. On admission<br />
lie was somewhat drowsy, and spoke slowly; there<br />
was ataxy of both upper and lower limbs, and the head and<br />
neck oscillated in an antero-posterior direction. There was<br />
nearly comnplete double external ophthalmoplegia, including<br />
double ptosis, more marked on the right side. There was<br />
some lateral nystagmus. The pupils were slightly and uneqtially<br />
dilated, and reacted to light. There was no optic<br />
neuritis nor choroiditis. The child could not see. A month<br />
later lie was semiconscious, swallowing with difficulty, and<br />
ithe arms and legs fell flaccid when lifted from the bed. He<br />
,becaine more unconscious, the breathing became of the<br />
4Clieyne-Stokes character, swallowing became difficult and<br />
finally impossible, and he died two months after admission,<br />
-or six months after the first symptoms. The necropsy showed<br />
that the cerebellum was perfectly healthy, but the corpora<br />
.quadrigemina were flattened, broader, and more extensive<br />
than normal, and grey and gelatinous in appearance. There<br />
wias a similar grey substance showing at the base of the<br />
Ibrain between the crura cerebri, and invading them in their<br />
inner halves; the third nerves were lost or torn away from<br />
their attachments. In the right orbit all the muscles supplied<br />
by the third nerve were atrophied, and the nerve and<br />
its branches could not be found; in the left orbit the nerves<br />
-ud their branclhes were present, and the muscles were fairly<br />
'healthy. The minute investigation of the parts was unsatisiaotory<br />
from failure in the preserving methods; but there<br />
-w.s n1o doubt that the corpora qiuadrigemina and adjacent<br />
jptrts were changed by new growth, probably of glio-sarcomatous<br />
niature. The case illustrated, more or less completely,<br />
the formula laid down by Nothinagel for the diagnosis of diseise^<br />
of, or in the neiglhbourhood of, the corpora quadrigemina.<br />
According to him, the diagnostic signs were "i an unsteady reel-<br />
inga gait, especially if this appeared as the first symptom," and<br />
" oplithalmoplegia existing in both eyes, but not quite sym-<br />
,metrically, nor implicating all the muscles in equal degree."<br />
)r. MOTT, speaking as a physiologist, said that the early<br />
'and persistent ataxic symptoms which seemed, as Nothnagel<br />
poinited out, when combined with oculo-m-iotor paralysis to<br />
be diagnostic, mih-lt be explained in one of three ways.<br />
k(l) The fillet might easily be involved, and physiologists con-<br />
*sidered that the fillet conveyed inpulses from the nuclei of<br />
'tle posterior columns of the spinal cord. According to<br />
Fleclisig alnd Hlisel, the fillet passed to the sensori-motor<br />
area of the central convolutions. The fillet was, therefore, in<br />
all probability a path for muscular sense impressions, and<br />
inasmuchl as it lay between the crusta of the crus cerebri<br />
and the corpora quadrigemina, a portion of it very close to<br />
tIme latter, it was difficult to understand how the fillet could<br />
escape if a tumour grew in these bodies. (2) Were the<br />
superior cerebellar peduncles involved ? They lay very close<br />
to the posterior corpora quadrigemina, and on the surface of<br />
tlhe Auperior peduncle turning round to reach the vermis.<br />
Just behlinid the posterior corpora lay the ventral portion of<br />
the direct cerebellar tract of the spinal cord. (3) A number<br />
of fibres could be traced up the antero-lateral columns of the<br />
spinal cord after their section, these fibres terminating in the<br />
corporla quadrigemina, and Dr. Mott suggested that possibly<br />
tlhey served to co-ordinate the spinal actions of the limbs and<br />
eyes.<br />
Dr. BrEEvOR had about ten years ago publislhed a case of a<br />
tumour that grew from the upper surface of the cerebellum.<br />
a-lnd comiipressed the corpora quadrigemina. There was ataxy<br />
combined witlh paralysis of ocular muscles, double optic<br />
neuritis, anid volniiting. The tumour pressed forwards on the<br />
corpora quadrigemina, as proved at the necropsy.<br />
Dir. TAYLOR, in reply, said hiis case sliowed that there might<br />
be ataxy in a clhild due to disease that was not in the cerebellum.<br />
lHe was confident thlre wwas no extensive lesion in<br />
the superior peduncle in his case, as the disease was almost<br />
entirely confined to the corpora quadrigemina.<br />
SYPHILITIc TuMOURS OF SPINAL CORD, WITH SYMPTOMS<br />
SIMULATING SYRINGOMYELIA.<br />
Dr. BEEV'OR detailed this case. P. S., aged 50, married,<br />
gardener, about two days after exposure to wet, on July 1st,<br />
1892, dragged the left leg and grew weaker in a few hours;<br />
he also had numbness in the right knee. In a few hours he<br />
had weakness of the left arm. On admission into the National<br />
Hospital for the Paralysed and Epileptic in September, 1892,<br />
he presented wasting of both the upper limbs, especially the<br />
left, anld weakness of the left lower limb so that he could only<br />
just raise the leg off the bed. Sensation was lost to pain,<br />
lheat, and cold in the right leg and the right half of the trunk<br />
up to the fourth rib, while tactile perception was normal.<br />
The knee-jerk was excessive on the left, and left ankle clonus<br />
was present. Later on the loss of painful sensation spread<br />
up to the right arm ulnar border, and involved the radial<br />
border of the left forearm. There was loss of electrical reactions<br />
in the interior muscles of the hand. Later he had<br />
paralysis of the sixth nerve of the right side, and he gradually<br />
became worse and died on November 14th. On examination<br />
post mortem two syphilitic tumours were found on either side<br />
of the brachial enlargement of the cord, the left one passing<br />
nearer the cord than the right, but the cord was too soft for<br />
accurate examination. Attention was drawn to the fact that<br />
loss of heat, cold, and painful sensations had lately been<br />
associated with syringomyelia when unattended by tactile<br />
anwesthesia, but in this case seemed to have been caused by<br />
pressure of a growth from without.<br />
Mr. EASTES asked for further information as to the treatment<br />
adopted in the case.<br />
Dr. MoTT asked if there was a tumour on the right, as well<br />
as one on the left, side of the cord; and whether microscopical<br />
examination had been made to show what tracts<br />
were degenerated. In two cases of unilateral syringomyelia<br />
it lhad been reported that the analgesia was on the same side<br />
as the cavity in the cord.<br />
Dr. BEEvOR, in reply, said that the question of treatment<br />
had naturally turned on the diagnosis. The case had been<br />
regarded as one of tumour of the cord, and it was a question<br />
as to whether it was one to be explored by operation. The<br />
loss of heat and cold sensation pointed to syringomyelia,<br />
which was the diagnosis adopted. Small quantities of iodide<br />
of potassium were given, but the drug was not pushed. The<br />
patient's statement that lie had not had syphilis was believed.<br />
It was impossible to trace accurately the degeneration in the<br />
various tracts of the cord, as it was so very diffluent.<br />
<strong>MEDICAL</strong> <strong>SOCIETY</strong> OF LONDON<br />
J. SYER BRISTOWE, M.D., F.R.S., Presidenit, in the Chlair.<br />
MlVonday, November 13th, 1893.<br />
STRANGULATION OF THE TESTICLE DUE TO AXIAL ROTATION<br />
OF THE SPERMATIC CORD.<br />
AIR. EDMUIND OWEN reported a case of this nature. The<br />
patient was a schoolboy, aged 13, who had an undescended<br />
testicle on the left side. After bowling at cricket lie was<br />
seized with pain and tenderness in the left inguinal region,<br />
and began to vomit. He was soon afterwards sent into hospital<br />
as a case of strangulated hernia. Between the external<br />
abdominal ring and the scrotum was a painful swelling the<br />
size of a small lien's egg. There was no impulse in it, and<br />
the skin was not discoloured. On gently dragging the<br />
tumour downwards the spermatic cord was foiind to be free,<br />
and the external abdominal ring clear. Mr. Owen gave<br />
it as his opinion that the swelling was due to engorgement of<br />
the epididymis and testis, the result of rotation of the cord.<br />
On exposing the parts the cord seemed to be normal. Wlhein<br />
the capacious tunica vaginalis was opened much blood-stained<br />
serum escaped, the testis and epididymis being found<br />
blackish, and in a conditioni of potenitial gangrene.<br />
He, therefore, removed them after tying the cord.<br />
Subsequently, on carefully examining the parts, he<br />
discovered that the cord was twisted so close to the epididymis<br />
that the twist was hidden beneath the upper part of<br />
the tunica vaginalis, which itself was implicated in the
-Nov. 18, 1893.1 _ OBSTETRICAL <strong>SOCIETY</strong> OF LONDON. rM;ALJOURN 1103<br />
twist. The boy went home cured in less than a fortniglht.<br />
Mr. Owen briefly detailed eleven other cases of a like nature<br />
which had been recently reported--most of them in England.<br />
He thought that not a few cases of sloughing testieles<br />
and of testicles wasting after acute inflammation were<br />
of this nature. The condition was almost as likely to occur<br />
upon the right side as the left, but was specially likely to be<br />
found in boys and young adults who were the subjects of undescended<br />
testis. It was impossible to differentiate certain<br />
of these cases from strangulated hernia, but, as operation<br />
would probably be needed in each condition, the want of<br />
precision in diagnosis would lead to no harm. lie was of<br />
opinion that when the engorged mass was exposed the operation<br />
should be completed by its removal.<br />
Mr. T. BRYANT said he was the first to call attention to this<br />
particular condition, but he admitted his inability to aflord<br />
any satisfactory explanation of the twisting of the cord in<br />
such cases, though the association with undescended testicle<br />
or other developmental deformity was interesting. He<br />
failed to see the close resemblance to strangulated hernia<br />
that had been claimed. If the tumour could be separated<br />
from, or was outside, the ring the diagnosis was easy, but,<br />
under any circumstances, he pointed out that the local symptoms<br />
were much more intense in these cases than in hernia,<br />
and, in addition, the constitutional disturbance was absent.<br />
There was no abdominal pain, no abdominal distension, and<br />
the sickness was not persistent as was the case in hernlia.<br />
He agreed that early intervention was desirable, but he<br />
deprecated any rule for general application involving the<br />
routine removal of the testicle.<br />
After some remarks from Mr. NASH, Dr. RICHARDS suggested<br />
that there might be a congenital twist of small extent<br />
which became complete subsequently.<br />
Mr. OWEN, in reply, admitted the possibility of a congenital<br />
twist.<br />
NEPHRECTOIMy FOR HYDRONEPHROSIS.<br />
Mr. BL<strong>AND</strong> SUTTON read a paper on this subject. He wished<br />
to call attention to the comparative safety of nephirectomy<br />
when carried out on certain definite lines. The greater part<br />
of the cases of hydronephroses were due to obvious obstruction<br />
in some part of the genito-urinary tract, hence they were<br />
termed retention cysts. Such hindrance to the flow of urine<br />
to produce hydronephrosis must be incomplete, or if complete,<br />
only temporary, for when the ureter was completely<br />
and permanently blocked the kidney rapidly atrophie(l. Ihe<br />
most startling fact was tlhat in many of the largest hydroniephroses<br />
no obstruction could be demonstrated, and this<br />
could not in most cases be explained on the hypothesis of<br />
ablnormal movements of the kidneys. Thle largest lhydro-<br />
niephroses were those subject to intermissions, tlley underwent<br />
great dimilnution a-nd even temporary disappearance.<br />
He related a case in whiclh such an intermission took<br />
place during the operation for its relief. In this<br />
case there was no evidence of obstruction, nor, owing<br />
to the connections of the cyst, could abnormal movements<br />
have been possible. He showed an unusual specimen of<br />
unilateral hydronephrosis removed, post mortemn, from an old<br />
iiman in whom no trace of obstruction could be found.<br />
Although the course of a hiydronephrosis was silent, it<br />
promptly revealed its presence if it suppurated. This was<br />
one of the greatest dangers to which such patients were<br />
liable. They must distinguish between a pyonephrosis and a<br />
suppurating hydronephirosis. The latter was comparable to<br />
a suppurating ovarian cyst, and required the same principles<br />
of treatment. A primary pyonephrosis was inflammatory<br />
from the onset; it rarely attained a large size, and, as it wvas<br />
usually associated with calculus, it demanded nephrolithotomy<br />
or nephrotomy rather than neplhrectomy. A hydronephrosis<br />
miglht become septic through the colon, for in<br />
some cases the wall separating the cyst from the colon miglht<br />
bec-ome so thin as to permit of osmosis of fluid, and so establisli<br />
suppuration. In such cases the synmptoms might simulate<br />
those of typhoid fever, of which he meiitioned an example.<br />
The recognition of a suppurating hydronephrosis<br />
was comparatively easy, but it was extremely important to<br />
distinguish between renal tuberculosis, pyonephrosis due to<br />
calculus, and a suppurating hydronephrosis. The practice of<br />
resorting to aspiration for diagnostic purposes could not be<br />
too strongly condemned, for it often misled, and was, more-<br />
over, the source of much danger. As to treatment, the<br />
disorganised organ slhould be removed if the other was in good<br />
working order. The removal of one'lydronephrotic kidney,<br />
if both were similarly,affected, might lead to disaster. In such<br />
cases nephrotomy was safest. The principal points in the<br />
operative procedure were-having opened the peritoneal<br />
cavity in front in the middle line to establish the diagnosis,<br />
the wound was closed, and the cyst was exposed through an<br />
incision in the ileo-costal space. No attempt should be<br />
made to enucleate,the tumour until the finaer was well within<br />
the capsule-a point to which he attached considerable importance.<br />
After emptying and ligaturing any large dilated<br />
ureter, the pedicle should be transfixed as close to the cyst as<br />
possible. The pedicle should never be clamped with large<br />
forceps before securing the ligature. Success in nephrectomy<br />
demanded decision, celerity, and gentleness-qualities which<br />
could only be acquired by constant familiarity with renal<br />
operations. The fate of a patient who had undergone<br />
nephrectomy, judging from the facts at his disposal, was, on<br />
the whole, very reassuring.<br />
Mr. ALBAN DORAN deprecated operating with too mucl<br />
haste in hydronephrosis associated with floating kidney,<br />
because this might ultimately subside of itself. He related<br />
a very striking instance in which the tumour disappeared<br />
only a few hours before the nephrectomy was to be done. In<br />
that case a floating kidney remained, which had since been<br />
kept in position by means of a belt, and no recurrence<br />
had taken place. In another case the ureter, though not<br />
altogether impervious, would not empty the cyst unless the<br />
kidney was turned upside down, so that no natural relief<br />
could be anticipated. He objected to nephrotomy because a<br />
second operation so often became necessary. Even hydronephrosis<br />
of long standing did not appear necessarily to involve<br />
atrophy of the kidney substance, in which case restoration<br />
of function was more likely to take place if nephrotomy<br />
with drainage was resorted to, provided the ureter could be<br />
made patent.<br />
Mr. HENRY MoRRis admitted that no cause of obstruction<br />
could sometimes be discovered, but he pointed out that the<br />
original cause of obstruction might have become obliterated<br />
in the changes associated with the formation of a hydronephrosis.<br />
Obstruction low down in the ureter did not of<br />
necessity involve dilatation extending up the ureter and into<br />
the pelvis of the kidney, for the ureter might yield in one<br />
spot, and the bulge thus formed might press upon and<br />
obliterate the tube higher up, just as was the case in some<br />
aneurysms which obliterated the artery above or below. It<br />
did not follow, therefore, that the obstruction was in the<br />
pelvis of the kidney because no dilatation of the ureter could<br />
be found lower down. He suggested that various conditions<br />
might determine the formation of small cysts in the kidney<br />
substance, which by coalescing might go on to form a hydronephrosis.<br />
He alluded more particularly to two forms of<br />
liydronephrosis between which a distinction ought to be<br />
made-first, the thiin-walled hydronephrosis which collapsed<br />
if tapped during the operation, and the other variety in<br />
which hypertrophy of the cortex took place pari passu witl<br />
dilatation, so that on opening the kidney one saw the calices<br />
separated from one another by tllick fibrous septa. This<br />
variety might result from the wasting or removal of one diseased<br />
kidney, while the other underwent hypertrophy<br />
previous to dilatation in its turn. Such kidneys, he<br />
admitted, might require to be dealt with as solid tumours.<br />
In removing these tumours lie agreed that it was desirable to<br />
get well within the capsule before attempting enucleation,<br />
but he doubted whether this could be done in the case of<br />
thin-walled cysts, because in tryincg to get inside the cpsule<br />
one was likely to get inside the cyst cavity.<br />
Mr. SUTTON replied.<br />
OBSTETRICAL <strong>SOCIETY</strong> OF LONDON.<br />
G. E. HERMAN, M.B.Lond., F.R.C.P., President, in the<br />
Chair.<br />
Wednesda.y, Novemzber 1st, 1893.<br />
SPECIMENS.<br />
THE following specimens were shown:-Dr. LENVERS: Patient<br />
on wlhom he had performed Symplhysiotomy.--Dr. EDEN:<br />
Ovarian Cyst, with Sarcomatous Growth.-Dr. A. ROUTH:
1104 TMDICALBOUAL1 OBSTETRICAL <strong>SOCIETY</strong> OF LONDON. [Nov. 18, 1893.<br />
Fibroid of Broad Ligament.-- Dr. HAYES: Hydrosalpinx.-Dr.<br />
BoxALL: Uterine Myoma.<br />
A FOXTEER CONTRIBUTION TO THE CLINICAL KNOWLEDGE OF<br />
PUERPERAL DISEASES.<br />
Dr. J. BRAXTON HICKS read this paper. He said it had yet<br />
to be ascertained whether the variations in intensity might<br />
not be due to a greater or less quantity of the poison taken<br />
into the system, 6r to the greater susceptibility of the patient,<br />
or whether the specific poison was accompanied to a varying<br />
extent by other poisons generated from the same source; or,<br />
indeed, whether a modification or, in regard to bacteria,<br />
whether a new phase of growth (common to these organisms)<br />
might not determine a modification of kind as well as of<br />
intensity of the symptoms arising therefrom. He insisted on<br />
the fact that the rapidity of action of the poison, whatever it<br />
might be, was much greater than that seen in surgical cases<br />
generally; that gave rise to the question whether the entrance<br />
of the poison by the genitals and the special circumstances of<br />
the situation would suffice to explain the difference in this<br />
respect. Further, the special influence of the gonorrhceal poison<br />
contracted before delivery, and yet to be determined. Finally,<br />
in estimating the influence of infectious diseases, especially<br />
those which conferred some sort of immunity, it must be<br />
inquired how far patients had been rendered immune by a<br />
previous attack-a condition which must obviously be of<br />
frequent occurrence. His first group of three cases was<br />
derived from the practice of a medical man in a village where<br />
a young woman died after a day's illness of some obscure abdominal<br />
trouble, ascertainedpost mortem to be purulent peritonitis,<br />
the source of which could not be determined. The<br />
medical man attended a labour case the same evening, and<br />
another on the following day, followed by a third on the<br />
fourth. In less than a week all three were dead with similar<br />
symptoms. His next series started with a case of old-standing<br />
disease of the femur, in which a surgical examination was<br />
followed by an outbreak of phlegmonous erysipelas. Thereupon<br />
the practitioner ceased to attend midwifery, but after<br />
three weeks had elapsed, though still dressing the ulcers, he<br />
resumed his attendance on obstetric cases. The first died<br />
within thirty-six hours with symptoms of intense intoxication.<br />
A second died within two days of labour, and a third<br />
narrowly escaped. The medical man gave up attending cases<br />
for three or four weeks, but his first case after that interval<br />
died with pyrexia, headache, and a scarlatinal rash, and a<br />
woman whom he attended in an abortion shortly after had a<br />
similar fate. It transpired later that in the room in which the<br />
first fatal case occurred the previous tenant had died in<br />
the same bed of some offensive disease the nature of<br />
which could not be ascertained. Case VII was that of a<br />
young married lady in her first confinement. She had a<br />
fairly good labour, but the forceps was used, and within<br />
twelve hours she fell ill with the usual symptoms, and<br />
died three days later, a bright scarlet rash making<br />
its appearance pretty well all over the body. Eight<br />
days later the baby was attacked by erysipelas and died.<br />
No sanitary defect was found in that house, though diphtheria,<br />
attributed to a defective sewer, had occurred in the<br />
house of which the garden abutted on the garden of the<br />
house in question. Case VIII. A woman in the eighth month<br />
of pregnancy developed symptoms of influenza. Three days<br />
later premature labour set in, in the absence of the medical<br />
man, who only arrived half an hour later. She was then<br />
greatly exhausted with vomiting, had a high temperature,<br />
and complained of a pain in her " stomach.' Next day the<br />
temperature rose to 106.60, and the right elbow-joint was<br />
inflamed, distended, and painful. Diarrhoea supervened,<br />
and four days later the left elbow followed suit, and diphtheritic<br />
vulvitis made its appearance, the same condition<br />
then appearing on the throat. She died on the ninth day<br />
after delivery. The sanitary arrangements of the house<br />
appeared to be perfect, but there had been erysipelas and<br />
diphtheria in the neighbourhood. Case ix. A woman whom<br />
he saw in consultation four weeks after her confinement was<br />
thought to be suffering from influenza, several cases of which<br />
had occurred in the house. After a few days of feverishness<br />
the perineal rent, which had been stitched up, became -inflamed<br />
and became the seat of erysipelas. This condition<br />
lasted three weeks, but when Dr. Braxton Hicks saw her the<br />
erythema had subsided. This patient recovered. The child!<br />
was not affected. It afterwards came to his knowledge that.<br />
the nurse had been nursing her mother with erysipelas just<br />
before. They could not fail to be struck by the extreme<br />
virulence of the virus, only a small quantity of which could<br />
have been introduced. It seemed to him, moreover, that<br />
the amount of poison received by the patient diminished as<br />
time lengthened between the original infection of the hand<br />
and the infection of the patient, which probably amounted<br />
to saying that the rapidity and severity of the symptoms<br />
depended on the quantity of the poison received. He was<br />
unfortunately unable to give any information as to the kind<br />
of purification of the hands (if any) employed in these two,<br />
groups.<br />
Dr. ROUTH asked whether any special atmospheric influences<br />
were noted, as a low barometric pressure led to'<br />
emanation of gases from the earth. It was well known that<br />
before rain common sewers and drains were especially offensive<br />
and sources of infection.<br />
Dr. BOXALL thought that time might serve to dilute, but<br />
not destroy, septic material. He thought it ought to be<br />
generally known that by the adoption of efficient antiseptic<br />
precautions, rather than by abstaining from practice, must<br />
safety after exposure to infection be secured.<br />
Dr. H<strong>AND</strong>FIELD JoNEs had notes of three cases in which<br />
foul sewer emanations seemed to have played an important<br />
part in the production of puerperal poisoning, and he considered<br />
that a woman who for days or weeks before delivery<br />
lived in a tainted atmosphere mi ht be so impregnated with<br />
poisonous particles that after delfivery her tissues would become<br />
a favourable breeding ground for septic germs. Where<br />
such a condition occurred removal to a purer atmosphere<br />
hastened recovery.<br />
The PRMESIDENT wished to express in the strongest way his<br />
opinion as to the futility in preventing the transference of<br />
infection by mere temporaly abstention from practice. He<br />
did not believe that any mere lapse of time would ever disinfect<br />
infected hands and clothes. On the other hand, if the<br />
person, instruments, and clothes were properly disinfected<br />
(which could be done in a few hours), there was no necessity<br />
for further abstention from practice. Many cases were published<br />
in which patients who were delivered in houses with<br />
defective drainage had been attacked with puerperal illness,<br />
and had begun to improve on removal to a purer atmosphere,<br />
but he knevr of no evidence that the relation between the<br />
drainage and the illness was anything more than coincidence.<br />
A paper was recently read before the Epidemiological Society<br />
by Dr. Sweeting, in which he endeavoured to prove the connection<br />
between outbreaks of diphtheria and bad drains, but he<br />
entirely failed to do so. He (the President) believed that.<br />
Duerperal septiciemia was produced by infection by contact.<br />
It did not necessarily follow that the medical man or the<br />
nurse was always the vehicle of contagion, although in the<br />
great majority of cases it was one of the two.<br />
Dr. HoRRocoe said that so long as a medical man was in<br />
attendance upon a puerperal fever case of the grave type he<br />
was unfitted for attending midwifery cases. So he should<br />
obtain the help of another practitioner either to attend the<br />
puerperal fever case or his other cases of midwifery. Whilst<br />
admitting the possibility of time not destroying germs, yet<br />
he thought it would have the same effect practically by<br />
ultimately getting rid of the poison. He considered absolute<br />
disinfection coull be secured in forty-eight hours (or even<br />
less) by a change of all garments, a bath, repeated washing of<br />
the hands, and placing them in an antiseptic solution.<br />
Dr. HAYES said what was wanted was a thorough cleansing<br />
of the hands, not mere washing in soap and water, but that<br />
conjoined with a 1 in 20 solution of absolute phenol. He<br />
thought the influence of drain poison or miasma, although a<br />
cause of puerperal septiciemia, had been greatly exaggerated.<br />
Dr. DUNCAN could not agree with the last speaker that it<br />
was superfluous to change the clothing before attending a midwifery<br />
case after having been in attendance on a case of puerperal<br />
septieaemia. He thought, however, that if the clothing<br />
was hung up in a small room and some iodine burnt over a<br />
spirit lamp, disinfection was secured. With this precaution,<br />
in addition to taking a bath and thoroughly washing the<br />
hands in soap and water, and afterwards dipping them in a 1 in<br />
1.000 mercuric chloride solution, lie considered he might
Nov. 18, 1893.] <strong>ROYAL</strong> ACADEMY OF MEDICINE IN IREL<strong>AND</strong>. [TM_BRIT 1105<br />
with perfect safety attend a midwifery ease in twenty-four<br />
hours.<br />
Dr. LEWEIRS believed that complete personal disinfection<br />
was quite possible, and that it was not at all essential for a<br />
man to abstain from midwifery practice because he had<br />
examined a case of puerperal fever. TIe was very sceptical<br />
as to bad drains having much to do with puerperal<br />
septieaemia.<br />
r. A. RouTH expressed his belief in the importance of<br />
sewer' gas in producing puerperal septiceemia, and mentioned<br />
some cases which he considered supported the view.<br />
Dr. CULLINGWORTH considered it a very dangerous doctrine<br />
to send forth that puerperal septicaemia could be caused by<br />
defective drains and sewer emanations. He agreed with the<br />
President as to the unimportance of the time element in ridding<br />
a man of infection. If thorouglh personal disinfection<br />
were carried out he did not think abstention from practice at<br />
all necpssary.<br />
Dr. FRANcIs TAYLOR asked whethler it was to go fortlh as the<br />
dictum of that Society that the presence or absence of sewer<br />
gas in the bedrooms of parturient women was a matter of<br />
little or no consequence? He quoted cases which pointed<br />
the other way.<br />
Dr. WALLACE pointed out that some of the cases mentioned<br />
supported the thesis indicated by the President, that<br />
there was no positive proof of the existence of a causal relation<br />
between sewer gas poison anld puerperal septiciemia. It<br />
was clear that where the pyrexia and other symptoms imme-<br />
'diately disappeared after the patients were removed from<br />
their insanitary surroundings, the cases were suffering from<br />
sewer gas poisoning and not from puerperal septicsemia.<br />
Dr. HICKS, in reply, said he had mentioned the atmospheric<br />
surroundings because in looking at the causes of puerperal<br />
-diseases it was proper to include all things that might act<br />
detrimentally to the pregnant and lying-in woman. At<br />
present we were ignorant on many of these points, and many<br />
of the speakers spoke with more positiveness than our knowledge<br />
justified. We used the term sepsis-septicamia, but as<br />
a matter of fact we did not know their nature, neither did we<br />
know what sewer gas was, nor how many poisons it might<br />
contain. What we did know was that it produced detrimental<br />
effects on the system, and in a lying-in woman ill.<br />
health interfered with the reparation necessary of those<br />
parts bruised, ecehymosed, and lacerated by labour; and so<br />
we may have absorption of unhealthy matter, and that<br />
whether any specific agent had been introduced or not.<br />
OPHTHALMOLOGICAL <strong>SOCIETY</strong> OF THE UNITED<br />
KINGDOM.<br />
-HENRY POWER, M.B., F.R.C.S., Vice-President, in the<br />
Chair.<br />
Thursday, November 9th, 1893.<br />
NEOPLASM OF THE IRIS.<br />
Mn. LAWFORD read the report of the Committee on Mr.<br />
Beaumont's case of Neoplasm of the Iris.<br />
BENZOYL-PSEUDO-TROPEINE AS A LOCAL AN.ESTHETIC IN<br />
OPHTHALMIC SURGERY.<br />
This paper was read by Mr. T. J. BOKENHAM. He said<br />
benzoyl-pseudo-tropeine, or tropa-cocaine, was a new cocabase<br />
extracted from the small-leaved coca plant of Java, and<br />
-was identical with the pseudo-tropeine obtained from<br />
hyoscyamus. The alkaloid as obtained from the plant had<br />
-considerable irritating properties when introduced into the<br />
eye, but this was not the case when it was obtained by<br />
synthesis. The specimen of the synthetically prepared alkadoid,<br />
in the form of hydroeblorate, was made into a 3 per<br />
-eent. solution, and tested by the author. It was found most<br />
-efficient for inducing aniesthesia of the cornea, and had the<br />
-advantage of causing no dilatation of the pupil, and none of<br />
the ischaemia characteristic of the action of cocaine. There<br />
was no disturbance of accommodation following its use. As<br />
an anaesthetic to the lid before applying mitigated stick or<br />
lapis divinus, a 10 per cent. solution had been found as<br />
,successful as a corresponding strengtll of cocaine. This had<br />
been found sufficient in such operations as strabismus,<br />
edivision of stricture of lachrymal duct, and opening of<br />
Meibomian cysts. Tropa-cocaine had the following advantages<br />
as compared with cocaine: It caused no dilatation of the<br />
pupil, and no disturbance of accommodation; it was much less<br />
poisonous than cocaine, and it did not, if swallowed, produce<br />
delirium. The vascular condition of the eye was not affected<br />
by it, and in the form of a solution it kept better than<br />
cocaine.<br />
SPONTANEOUS RUPTURE OF CAPSULE AFTER IRIDECTOMY<br />
PRELIMINARY TO CATARACT EXTRACTION.<br />
This paper was read by the SECRETARY for Mr. J. T. RUDALL<br />
(Melbourne). Five months after an uncomplicated preliminary<br />
iridectomy it was found that the cortex of the lens had<br />
undergone partial absorption, allowing a clear space between<br />
the nucleus, which appeared to be somewhat tilted backwards,<br />
and the upper edge of the cornea. It was probable<br />
that a limited spontaneous rupture of the capsule had taken<br />
place. Fearing that the nucleus of the lens might fall back<br />
into the vitreous, the author removed it with a vectis. No<br />
vitreous was lost, and the recovery was uncomplicated.<br />
EXTREME HYPHAEMIA OF BOTH EYES WITH CORNEAL ABSCESS<br />
OF RIGHT EYE OCCURRING AS A SEQUELA OF SMALL-POX.<br />
This paper was read by the SECRETARY for Mr. KENNETH<br />
SCOTT (Cairo). Ten months before admission into the Kasrel-Aini<br />
Hospital the patient, a boy aged 9, had been attacked<br />
by small-pox, which was immediately followed by loss of<br />
vision in both eyes. At the time of admission there was a<br />
circumscribed abscess of the centre of the right corn,a, the<br />
anterior epithelium being intact. There was no pain nor<br />
lacrymation, and only moderate injection. The anterior<br />
chambers of both eyes were filled with a dark red brown<br />
mass, completely concealing the iris. There was no trace of<br />
irritation of the left eye. The tension of both eyes was normal.<br />
Vision equalled perception of light. After seven weeks'<br />
treatment the corneal abscess disappeared, and the upper<br />
third of the red brown mass in both anterior chambers had<br />
become of a light buff colour, and quite transparent. The<br />
patient was kept under observation three months longer, but<br />
the eyes remained in exactly the same condition.<br />
CARD SPECIMENS.<br />
The following were the card specimens: Messrs. CBITCHETT<br />
and JULER: A Case of Pemphigus of the Conjunctiva.-Mr.<br />
G. <strong>AND</strong>ERSON CRITCHETT: A Case of Conical Cornea treated by<br />
the Galvano-Cautery without Perforation.-Mr. JULER: A<br />
Case of Central Colloid Changes in the Retina. - Mr.<br />
FREDERICK BASS: A Pocket Refraction Case.-Dr. RAYNER<br />
BATTEN: Persistent Hyaloid Artery branching in Vitreous.<br />
Mr. DONALD GUNN: A case of Sypllilitic Conjunctivitis.<br />
<strong>ROYAL</strong> ACADEMY OF MEDICINE IN IREL<strong>AND</strong>.<br />
SECTION OF PATHOLOGY.<br />
Professor-J. ALFRED SCOTT, President, in the Chair.<br />
Friday, November 3rd, 1893.<br />
PRESIDENT'S ADDRESS.<br />
THE PRESIDENT delivered his opening address on the Microchemistry<br />
of Cells in Relation to the Theory of Immunity.<br />
SPINA BIFIDA OCCULTA.<br />
Dr. J. O'CARROLL exhibited a patient suffering from a<br />
fairly typical favus eruption on the head. She had also a<br />
large tuft of hair on the sacral or lumbar region, and a<br />
peculiar deformity about the left scapula at its superior<br />
angle, looking like an exostosis. It was interesting to know<br />
that a little sister of hers had a large meningocele in that<br />
region. He thought that the one he exhibited would come<br />
under the name of spina bifida occulta.<br />
SPECIMENS.<br />
Dr. J. WV. MOORE showed the heart of a police recruit,<br />
aged 21, who died on the ninth day of Acute Rheumatism,<br />
the axillary temperature rising to 108.6° shortly before and<br />
to 1100 shortly after death. The heart was hypertrophied<br />
but softened. The aortic valves were healthy, but a large<br />
clot adhered to the mitral valve, blocking up its lumen to a<br />
very serious extent. The sequence of pathological phenomena<br />
probably was an attack of rheumatic endocarditis in
1106 Mrn CAL Jous I BIRMINGHAM <strong>AND</strong> NMIDL<strong>AND</strong> COUNTIES BRANCH. LNov. 18, 1893.<br />
1891, involving the margin of the mitral valve, an escape and<br />
consequent perishing of leucocytes, which excited fermentation<br />
and caused coagulation of the blood, thus leading to the<br />
formation of this great clot, which resembled a vast valvular<br />
excrescence, outgrowth, or vegetation.-Dr. JAMES LITTLE<br />
next exhibited a specimen of Mitral Narrowing due to atheromatous<br />
change, taken from a man, aged 60, who had swelled<br />
feet, short breathing, and the various signs of mechanical<br />
congestion of the venous system.-Dr. M'WEENEY showed a<br />
Round-celled Sarcoma removed on October 10th by Mr. Chance<br />
from a woman, aged about 50. The tumour was situated on<br />
the inner side of the thigh, a little below the knee, embedded<br />
in the subcutaneous fat, and at the time of removal had<br />
attained the size of a large orange. A nodule, about the size<br />
of a walnut, was removed at the same time from a point a<br />
few inches below the large tumour. Both growths were<br />
rounid-cell sarcomata with distinctly alveolar arrangement.<br />
The cells were large, witlh vesicular nuclei and an abundance<br />
of protoplasm. The nuclei contained granules which exhibited<br />
strong affinity for acid aniline stains, and bodies<br />
closely resembling the so-called cancer parasites could be<br />
seen. Numerous mitoses were visible, many of them being<br />
asymmetrical, and hyperchromatosis was of frequent occurrence.-Mr.<br />
STORY exhibited Sections of an Eye removed<br />
from a healthy young man, who lhad subsequently lost the<br />
sight of his second eye from a similar affection. The globe<br />
was removed on account of secondary glaucoma, which lhad<br />
not as yet shown itself in the second eye.-Dr. E. J.<br />
M'WEENEY exhibited Urinary Organs from a case of Cystitis<br />
witlh Surgical Kidneys.______<br />
LEEDS <strong>AND</strong> WEST RIDING MEDICO-CHIRUR-<br />
GICAL <strong>SOCIETY</strong>.<br />
J, KILNER CLARKE, M.A., F.R.C.S., President, in the Chair.<br />
Fr iday, Novemnber 3rd, 1893.<br />
SURGERY OF THE SPINE.<br />
MR. NORM[AN PORRITT read notes of a case of intraspinal<br />
abscess, the result of caries of tlle posterior surface of the<br />
lower cervical and first dorsal vertebrw, and of a case of dislocation<br />
of the seventh cervical vertebra. In the first case<br />
laminectomy was done, and the patient died eighteen hours<br />
after the operation from hyperpyrexia; in the latter the patient<br />
lived a year all but eleven days, although a fortnight<br />
after the injury he nearly died from apyrexia, the temperature<br />
sinking to 900 F., at the same time that the pulse and<br />
respirations dropped to 31 and 7.1 respectively per minute.<br />
Mr. MAYO ROBSON referred to the case of a little boy, suffering<br />
from caries of the spine with paraplegia. In this case<br />
he had removed some laminae, relieving the pressure, the<br />
child making a good recovery. Some time after this, the<br />
patient injured his back, and again became paraplegic. Some<br />
bone was removed in the site of the old incision, which had<br />
pressed on the cord. The patient's condition was somewhat<br />
improved. He was still under observation.<br />
Remarks were also made by the PRESIDENT, Mr. W. HALL,<br />
and Dr. TREVELYAN.<br />
TRAUIMATIC CYST OF THE PANCREAS.<br />
Mr. W. H. BROWN read notes of this case. A lad, aged 17,<br />
was struck violently in the abdomen by a buffer of an engine<br />
on March 20th, 1893. He was removed to a hospital in North<br />
Yorkshire. The abdonmen became swollen, and was tapped<br />
on the left side; 70 ounces of blood-stained fluid removed.<br />
Six weeks later 60 ounces were withdrawn. He was doing<br />
well until January 27th,, when lhe fell from a horizontal bar,<br />
immediately became velry ill, anid was admitted to the Leeds<br />
Infirmary. On admission, he liad severe abdominal pain;<br />
abdomen generally distended, tender, dull on percussion.<br />
The symptoms becoming more marked, Mr. Brown made an<br />
incision into thle abdomen, in the median line below the<br />
umbilicus. About 3 pints of blood-stained fluid escaped; a<br />
drainage tube inserted. None of the pancreatic ferments<br />
could be found in this fluid. The patient improved for a few<br />
days, but on July 4th a large swelling was noticed in the<br />
'Ipper part of the abdomen: there was a good deal of pain<br />
and some vomiting. The abdomen was now opened about<br />
the umbilicus, the stoinach and omentum drawn up, and the<br />
wall of the cyst exposed; this was punctured with a trocar, and<br />
3 pints of dark-coloured, peculiar-smelling fluid withdrawin .<br />
The opening in the cyst was enlarged, and the edges attached<br />
to abdominal wall, and drainage tube inserted. The fluid<br />
contained the pancreatic ferments. Seven weeks later the<br />
boy was discharged, well. The author emphasised the advantage<br />
of incision over tapping.<br />
Mr. LITTLEWOOD referred to a case of traumatic cyst of the<br />
pancreas he had read before the Clinical Society in 1892. He<br />
found on introducing his finger into the cyst he could very<br />
easily have opened it from behind on the left side, just below<br />
the level of the twelfth rib, and urged that these cases should<br />
be first explored in this region, and if fluid was found, to be<br />
opened here, and so avoid a peritoneal operation. He remarked<br />
that his case, and another he had seen, were certainly<br />
effusions behind the ascending layer of the transverse mesocolon<br />
in the neighbourhood of the pancreas, and not effusions<br />
into the lesser peritoneal sac, for in both cases the layers of<br />
the omentum did not form the cyst wall.<br />
Dr. EDDISON thought some of these cases cleared up after<br />
repeated tappings.<br />
Mir. NORMAN PORRITT referred to a case under hiis care, in<br />
which he had twice aspirated, the cyst again filling, so he<br />
opened the cyst and stitched it to the abdominal wall; a<br />
sinus still persisted.<br />
RECURRENT APPENDICITIS.<br />
Mr. MIAYO ROBSON related four cases of recurrent appendicitis,<br />
in which he had successfully removed the appendix<br />
in the quiescent period between the seizures.. Two of the<br />
patients were women, aged 22 and 27 respectively, the other<br />
two being men aged '23 and 31. In all the cases there had<br />
been numerous seizures, and in some of them the symptoms<br />
had been so severe as to threaten life. He also referred to a<br />
number of other cases in which he had operated, and made<br />
some remarks on the pathology of appendicitis, dwelling on<br />
the anatomical structure of the appendix vermiformis as<br />
being such as to predispose it to inflammation, there being<br />
simply a layer of epithelial tissue protecting the underlying<br />
adenoid tissue from infective organisms.<br />
The paper was discussed by the PRIESIDENT, Mr. DRAPER,<br />
Mr. W7. HALL, Dr. BRAITHWAITE, and Dr. EDDISON.<br />
CASES <strong>AND</strong> SPECIMENS.<br />
Mr. LITTLEWOOD showed a woman, aged 53, from whom he<br />
had removed a AIalignant Mass from the Ascending Colon,<br />
stitchling the divided ends of the colon by silk sutures after<br />
Halstead's method. The patient made a good recovery.--<br />
Dr. IRVING (Huddersfield) showed a successful case of Trephining<br />
for Haemorrhage from the Middle Meningeal Artery.<br />
-Mr. PICKLES showed a Fcetal Monstrosity.-Dr. E. SoLLY<br />
(Harrogate) showed a specimen of Strongylus Gigas from the<br />
Human Subject, passed per ?#rethram. - Dr. TREVELYAN:<br />
Some microscopic and other specimens of Diseased Cerebral<br />
Arteries.-Dr. WARPROP GRIFFITH: (1) Case of Congenital<br />
Heart Disease. (2) Case of Unusual Cardiac Bruit.-<br />
Mr. HARTLEY: Congenital Neevoid Lipoma in a Child, aged<br />
4 years.<br />
BIRMINGHAM <strong>AND</strong> MIDL<strong>AND</strong> COUNTIES<br />
BRANCH OF THE BRITISH <strong>MEDICAL</strong><br />
ASSOCIATION.<br />
PATHOLOGICAL <strong>AND</strong> CLINICAL SECTION.<br />
BENfNETT MAY, MI.B., F.R.C.S., President, in the Chair.<br />
Friday, October 27th, 1893.<br />
CASES.<br />
DR. E. N.\NASON showed a patient, aged 22, whom he had<br />
trephined three years ago for Cerebral Abscess, which was<br />
localised by focal symptoms to the centre of the left arm and<br />
left side of face and tongue. An abscess was found in the<br />
suspected area and drained, with the result of a complete recovery.<br />
Some six or eight months later the patient had a<br />
series of epileptiform seizures, in each case apparently determined<br />
by a too free use of alcoholic stimulants. These<br />
attacks were preceded by a sensory aura, consisting of apeculiar<br />
taste sensation on the left side of the tongue. These<br />
attacks had now ceased, and the young man seemed in perfect<br />
health. I)r. Nason also showed apatient with symptoms
Nov. 18, 189S.] PLYMOUTH <strong>MEDICAL</strong> <strong>SOCIETY</strong>. TMii Biam 1107<br />
Nov.18,1893.1 r..D.... OU..,L~~~~~~~~~~~~<br />
of increased Intraorbital Pressure, probably due to a slowlygrowing<br />
sarcoma of the orbit.-Mr. MORISON showed a boy,<br />
aged 15, on whose right foot he had performed Tarsectomy.<br />
The boy was born with a double congenital club foot. The<br />
result of the operation was eminently successful. The contrast<br />
between the two feet was very striking; and it was proposed<br />
to deal with the left one similarly at an early date.<br />
Mr. EALES showed a case of Hemianopsia in a woman, aged<br />
33. Complete right homonymous hemianopia, with contraction<br />
of remaining half fields. Central vision normal. Ophthalmoscopic<br />
appearances normal. The contraction of remaining<br />
half fields was probably functional, as it varied in<br />
degree at different times of the day.-Dr. LESLIE PHILLIPS<br />
presented a youth suffering from Lupus with Intercurrent<br />
Syphilis.<br />
SPECIMENS.<br />
Dr. FOXWELL showed a Brain, with a glioma the size of a<br />
hen's egg occupying the right motor area, but not involving<br />
the basal ganglia. Its exact contour was impossible to determine,<br />
but its centre occupied the ascending frontal convolution.<br />
No abnormality was detected elsewhere within the<br />
skull. The patient was a woman of 26, who, sixteen years<br />
previously, had been knocked down by a hand cart, and received<br />
a severe blow on the upper part of the left parietal<br />
region. Three years ago she had a fit, beginning as a " cramp "<br />
in the left leg. Similar attacks of Jacksonian epilepsy recurred<br />
about once a month. When admitted to the Queen's<br />
Hospital (in May, 1893) she was found to have double optic<br />
neuritis, double ptosis, double facial paralysis, paresis of all<br />
four limbs-much more marked on the left side-no sensory<br />
change, ankle clonus on both sides, but patellar clonus on<br />
the left side only. There did not appear to be sufficient<br />
localisation to justify operation. Towards the end of September<br />
she developed pneumonia, and died comatose.-Dr.<br />
SIMON showed the Intestines from a case of Enteric Fever.-<br />
Mr. MARSH showed: 1. An Adeno-sarcoma, the size of a<br />
large walnut, removed from the left breast of a woman, aged<br />
:32. Two months after the excision of the tumour she came<br />
with a similar but smaller growth in the right breast, and<br />
with distinctly enlarged glands in both axilla. There was no<br />
recurrence in the left breast. 2. An Adeno-sarcoma, the size<br />
of a Tangerine orange, removed from the left breast of a girl<br />
aged 19. 3. A Proliferous Cystic Adeno-sarcoma, the size of<br />
a large orange, removed with the breast of a woman, aged 51.<br />
4. A Breast, with multiple cysts, removed from a woman,<br />
aged 39, which, in some of its features, had clinically resembled<br />
a scirrhous growth.<br />
MANCHESTER <strong>MEDICAL</strong> <strong>SOCIETY</strong>.<br />
C. E. GLASCOTT, M.D., President, in the Chair.<br />
Wednesday, November lst, 1893.<br />
ACROMEGALY.<br />
DR. DRESCHFELD showed a patient, aged 30, who five years<br />
ago began to present signs of acromegaly. The bones of the<br />
skull and face were enlarged, especially the lower jaw; the<br />
hands and feet showed the characteristic thickening and enlargement<br />
which was manifest also to some extent in the<br />
bones of the forearm and clavicles. There was atrophy of<br />
both optic discs, with complete blindness of one eye and<br />
diminished vision, but no hemianopsia of the other. The<br />
thyroid could not be felt, but on each side was a well-defined<br />
swelling dipping down into the thorax, and being apparently<br />
connected with a mass there which gave rise to distinct dulness<br />
on percussion over the upper part of the sternum. The<br />
voice was hoarse, and the epiglottis was distinctly thickened,<br />
but there was no paralysis of the vocal cords. The subjective<br />
symptoms consisted in occasional pains in the head. There<br />
was also marked sexual weakness. The patient sought admission<br />
into hospital in consequence of excessive dyspncea,<br />
which soon yielded to arsenic, with distinct diminution in<br />
the size of the tumour masses in the neck. He was now<br />
able to follow his work. Dr. Dreschfeld discussed the pathology<br />
of the affection upon the evidence of the hitherto published<br />
necropsies, Neither the persistence of the thymus nor<br />
the enlargement of the pituitary body, which must be considered<br />
as only one of the symptoms, could be looked upon as<br />
the cause of the disease, which appeared to be more of a neurotrophic<br />
nature.<br />
HYDATIDS OF OMENTUM.<br />
Mr. E. STAN MORE BISHOP mentioned a case of onental<br />
hydatids, and showed the patient, together with microscopic<br />
preparations of acephalocysts, scolices, and hooklets from the<br />
tumour. Special attention was drawn to the fact of the extraordinary<br />
mobility of the tumour under chloroform, as a<br />
point of diagnostic importance between hepatic and omnental<br />
forms.<br />
RUPTURE OF URINARY BLADDER.<br />
Mr. THOMAS JONES mentioned a case of intraperitoneal<br />
rupture of the bladder, caused by falling against a wringing<br />
machine while the bladder was full. Laparotomy was performed<br />
forty hours afterwards, and the edges of the rent<br />
brought together with twenty-one interrupted silk sutures.<br />
Death occurred six days later, apparently from exlhaustion,<br />
consequent on persistent diarrhcea. Post-mortemn examination<br />
showed the rupture to be securely and perfectly watertight.<br />
There was no peritonitis of post-operative origin.<br />
SELF-RETAINING LARYNGOSCOPE.<br />
l)r. MOIRITZ demonstrated a self-retaining laryngoscope.<br />
NOTTINGHAM3 MEDICO-<strong>CHIRURGICAL</strong> <strong>SOCIETY</strong>.<br />
WALTER HUNTE:R, M.B., President, in the Chlair.<br />
Wednesday, November 1st, 1893.<br />
PRESIDENTIAL ADDRESS.<br />
THE PRESIDENT delivered an address on " The Comfort of the<br />
Patient: Practical Hints Thereon.' He took as a text:<br />
" What shall a man eat, what shall he drink, and wherewithal<br />
shall he be clothed? " All indigestible food the sick<br />
man should avoid, or whatever his idiosyncrasy dictated to<br />
him as difficult of digestion. Alcohol had its proper place<br />
among the drugs, but it was not a food. In drunken persons<br />
and in delirium tremens he advocated kola wine. He laid<br />
stress on the value of wool clotlhing next the skin, explaining<br />
how cotton, becoming saturated with sweat, clings to the<br />
skin, while the perspiration passes through wool, which not<br />
only was non-coinductor of heat, but from its elasticity did<br />
not cling to the skin; wool was, moreover, Nature's covering.<br />
In all febrile conditions he advocated the use of woollen<br />
night dresses and the patient to be in blankets with no<br />
sheets. He expressed an abhorrence for feather beds. As<br />
regards the relief of pain he dealt chiefly with facial neuralgia.<br />
aud gastralgia; for the former lie advocated quinine, phosphorus,<br />
or gelseminum; and he said that the latter could b6o<br />
distinguished from dyspepsia by the presence.of actual pain,<br />
whereas in dyspepsia there was swelling and discomfort but<br />
no pain; gastralgia often existed with anaemia in young<br />
women, and was best treated by quinine, and when anamnia<br />
existed also by treating this. For eczema he recommen6de<br />
an ointment composed of liq. carbonis detergens, vaseline,<br />
and hydrarg. am., or Unna's zinc paste applied as a dressing<br />
with several layers of butter cloth.<br />
VOTE OF THANKS.<br />
A vote of thanks to the President for his address was<br />
proposed by Dr. BIRNIE. seconded by Dr. POWELL, ancl carried<br />
by acclamation.<br />
PLYMOUTH <strong>MEDICAL</strong> <strong>SOCIETY</strong>.<br />
MARCuS BULTEEL, L.R.C.P., M.R.C.S., in the Chair.:<br />
Wednesday, November Sth, 1893.<br />
CASES.<br />
MR. Lucy showed a patient, aged 52, in whom the head of thie<br />
left Humerus was Excised three months ago for the relief of<br />
pain, fixity, and paralysis of themusculo-spiral nerve following<br />
a dislocation, which had remained unreduced three montlhs.<br />
The wound was now healed, and movement good. MIr. Luicy<br />
also exhibited a man, aged 21, in whom the Flexor Profunidus<br />
Tendon going to the left mniddle finger was successfully<br />
United with two chromic gut sutures. There was noW comnplete<br />
power of flexion.-Mr. C. E. RUSSEL RENDLE denmonstrated<br />
the result of a Mules's operation, performed sixteen<br />
days previously, for Destructive Syphilitic Kerato-iritis of th-e<br />
Right Eye. A silver-gilt globe was inserted and movements<br />
of the stump were now excellent. Mr. Rendle also showed<br />
a clay labourer, aged 35, with Myopia and Nyctalopia.<br />
With antisyphilic treatment and suitable concave glasses
1108 Taw BLmJl ] REVIEWS. [Nov. 18, 1893.<br />
NtsLICAL JOURNA^L]<br />
some improvement was gained.--Mr. Licy showed a boy,<br />
aged 18, invalided out of the navy nearly two years ago for<br />
D)ouble Empyema following Influenza. The right side was<br />
incised, and healed in three months. Resection of the ribs<br />
w1s found necessary on the left side. There was good expansion<br />
of the side, and the patient had gained flesh. Mr.<br />
L ley exhibited a Slide of Fluid removed from an Encysted<br />
Hydrocele of the Left Epididymis of a man, aged 53.<br />
DIAGNOSIS OF SCARLET FEVER <strong>AND</strong> INFLUENZA.<br />
Mr. HARLEY COUGH raised the question of diagnosis between<br />
scarlet fever and influenza, more especially as regarded<br />
desquanlation after each.<br />
REVIEWS.<br />
AN ELEFMET`.NTAiRY TEXTBOOK OF BIOLOGY, COMPRISING AVEGE-<br />
TABIAE ANI) ANIMAL MORPHOLOGY <strong>AND</strong> PHYSIOLOGY. By J.<br />
R. AINSWOwRTH DAVIS, B.A., Trinity. College, Cambridge,<br />
Professor of B3iology and Geology in the University College<br />
of WVales, Aberystwyth. London: Clhas. Griffin and Co.,<br />
Limited. 1893. Second editionl, revised and enlarged.<br />
(Vol. I, crown Svo, pp. 300. 8s. 6d. Vol. II, crown 8vo, pp.<br />
416. lOs. 6d.).<br />
IN this, the second, edition of Mr. DAVIS'S textbook there has<br />
been imluclh addition of material and considerable alteration<br />
in the text, so much so that the work is now divided into two<br />
volumnes, the first dealing with vegetable, and the second<br />
with animal morphology and physiology. The scope of the<br />
work is much greater than that usually found in biological<br />
textbooks, and in the second volume the author tells us he<br />
lhas attempted to bridge over the gap between the courses of<br />
z-)ology and humani anatomy as successively taken in a<br />
medical curriculum.<br />
A good feature of the work is that it justifies to a great<br />
extent the appellation of a textbook of biology. Not only is<br />
the structure of the types considered adequately given, but<br />
muclh trouble lhas been devoted to the far more important<br />
subjects of comparative morphology and physiology. No<br />
attempt has been made to render the work a practical or<br />
laboratory book; in this we think the author has acted wisely,<br />
there being already an ample supply of excellent works in<br />
this direction. Taking the two volumes together, they contain<br />
an imnmiense amount of information in a very concise<br />
forni; and although the amount of detailed description is<br />
large, it is so correlated and woven into an organic whole by<br />
means of repeated comparison, that the reader is ever reminded<br />
that it is a co-ordinated science he is reading, and<br />
not a mere collection of separate anatomies-an impression too<br />
often carried away by a biological student after completing<br />
the usual preliminary course in that subject.<br />
In the first volume, the excellence of the illustrations,<br />
many of which are drawn from the classical work<br />
of Sachs, will be appreciated. The diagrams of lifehistories<br />
are also noticeable, but their clearness would be<br />
greatly increased by the freer use of various types, and a<br />
more marked indication of the dominant phase in each. In<br />
the secondl volume, although the description of the types is<br />
correlated in many respects by the addition of the elements<br />
of tlleir embryology, yet this characteristic, wlhich is so<br />
marked in the first volume, is here not quite so well carried<br />
out. That there are greater difficulties in this portion of the<br />
orgaiiic kingdom we are well aware, and the autlhor is necessarily<br />
somewhat cramped in his treatment by the requirements<br />
of examining bodies.<br />
In a book of this kind, which is a biological textbook and<br />
not, as we have already said, a practical book, we could have<br />
wishied for a little less detail and more generalisation. Still,<br />
on the wlhole, it is certainly the best " biology " with which<br />
we are acquainted, and it owes its pre-eminence to the fact<br />
above stated, that it is an excellent attempt to present biology<br />
to the studentas a correlatedand completescience. Iheiglossarial<br />
index is a miost useful addition.<br />
AN EXA-MINATION OF WNEISMANNISM[. By GEORGE JOHN<br />
ROMANES, M.A., LL.D., F.R.S., Honoraly Fellow of Gonville<br />
and Caius College, Cambridge. London: Longmans,<br />
Green, and Co. 1893. (Cr. 8vo, pp. 934. 6s.)<br />
TIHE facts of heredity and the doctrine of evolution have<br />
bearings so important on medicine and pathology that any<br />
biologist who pretends to deal with them on broad grounds is<br />
sure of an attentive audience among members of the medical<br />
profession. Professor Weismann's theories have been very<br />
widely entertained in this country, and the interest which<br />
his writings have excited has done much to increase the<br />
amount of attention given to the fundamental questions of<br />
heredity. His theories have been noticed from time to<br />
time in these pages, and the changes which they have undergone<br />
have been briefly indicated. In the volume before us<br />
Mlr. ROMANES enters upon an elaborate criticism of the<br />
scheme elaborated by Weismann both in its penultimate and<br />
in its ultimate form.<br />
Mr. Romanes compares and contrasts Weismann's theory of<br />
heredity, and the extension of that theory to evolution, with<br />
the tlheories as to heredity propounded by Darwin and by Mr.<br />
Francis Galton. It may be convenient to reproduce here the<br />
brief sunmmaries of the three theories which Mr. Romanes<br />
gives. All three assume the existence of particulate elements<br />
of heredity. Darwin held that these particulate elements " all<br />
proceed centripetally from somatic cells to germ cells (gemmules);<br />
the inheritance of acquired clharacters is, therefore,<br />
habitual." Galton assumed that " these particulate elements<br />
proceed, for the most part, though not exclusively, from<br />
germ cells to somatic cells (stirp); the inheritance of acquired<br />
characters is therefore but occasional." Weismann's theory<br />
before its most recent modification was that " the elements<br />
in question proceed exclusively in the centrifugal direction<br />
last mentioned (germ plasm); the inheritance of acquired<br />
characters is therefore impossible."<br />
The first part of Mr. Romanes's book is directed to a criticism<br />
of the proposition that the movement of the particulate elements<br />
of heredity is exclusively in the centrifugal direction.<br />
He argues that facts do not warrant the assertion that germ<br />
plasm has shown an " absolute stability " since the first origin<br />
of sexual propagation, but only a very high degree of stability,<br />
as assumed by Galton.<br />
In the concluding chapter in the book, Mr. Romanes examines<br />
Weismann's latest work on The Germ, l'lasm, and<br />
shows that in it the theory of the absolute stability is given<br />
up, and the door is thus left open for the operation of<br />
Lamarckian factors. The question, therefore, as to the possible<br />
hereditary transmission of acquired characters remains<br />
open.<br />
The subjects discussed by Mr. Romanes are complex, and<br />
involve the use of a terminology which is not familiar; moreover,<br />
his style does not always contribute to the lucidity of<br />
his arguments. But the work is well worth reading, and we<br />
would recommend it to everyone who takes an interest in a<br />
question of fundamental importance to all branches of<br />
biology.<br />
VENTILATION <strong>AND</strong> HEAT. By JOHN S. BILLINGS, M.D.,<br />
D.C.L. New York: Tile EnDineering Record. 1893. (Demy<br />
8vo, pp. 500, fig. 210.)<br />
IN this volume Dr. BILLINGs treats all the imliportant matters<br />
connected with ventilation and hleating in a masterly way;<br />
his book will rank among the standard works on the subject.<br />
An interesting account of the history of ventilation is given<br />
at the commencement, and an extensive list of the general<br />
literature. Dr. Billings tells us that the history of ventilation<br />
began witlh tlle attempts to ventilate the Houses of Parliament<br />
in 1660 by Wren, and adds: " The history of these<br />
attempts would be almost equivalent to a hiistory of thle art<br />
of ventilation in its entirety."<br />
Several chapters are devoted to the chlemical and plhysical<br />
properties of the atmosplhere, anid very completely are the<br />
results of investigators collected and tabulated. This is<br />
markedly the case in the chapter on carbonic acid in the air,<br />
for no fewer than twenty-one tables are given, classifying the<br />
results of publislhed researches into the amount of the gas<br />
present under every variety of condition of the atmosphere.