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Development of an ICD Coding Definition for Inflammatory Bowel ...

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4.8.2 False negatives<br />

Considering the sensitivity <strong>an</strong>d specificity <strong>of</strong> our different sets <strong>of</strong> administrative<br />

definitions, the definition with the lowest acceptable sensitivity was chosen. A r<strong>an</strong>dom<br />

number <strong>of</strong> 35 PHNs were selected from the total number <strong>of</strong> FNs. Corresponding hospital<br />

chart numbers were extracted from EndoPro database <strong>an</strong>d charts were reviewed.<br />

The adv<strong>an</strong>tage <strong>of</strong> this approach was that the definition with the lowest acceptable<br />

sensitivity includes the FNs <strong>of</strong> the more sensitive definition as well.<br />

4.8.3 True positives<br />

To assess the reliability <strong>of</strong> EndoPro search in capturing IBD patients, we per<strong>for</strong>med a<br />

r<strong>an</strong>dom number <strong>of</strong> chart reviews (i.e. 33 patients) in the true positive group.<br />

4.9 Integration <strong>of</strong> charts reviews with EndoPro search<br />

In case there was a discrep<strong>an</strong>cy in IBD status between EndoPro search <strong>an</strong>d chart reviews,<br />

we considered the results <strong>of</strong> the chart reviews as the final decisive diagnostic tool.<br />

EndoPro IBD status was kept <strong>for</strong> patients whose charts were unavailable.<br />

Number <strong>of</strong> discrep<strong>an</strong>t cases in each cluster <strong>an</strong>d the reason <strong>for</strong> the discrep<strong>an</strong>cy were<br />

reported. A final data file containing the IBD status <strong>of</strong> our subjects was developed based<br />

on the final gold st<strong>an</strong>dard diagnostic tool (i.e. EndoPro search + Chart review).<br />

4.10 Selection <strong>of</strong> the final administrative definition <strong>for</strong> IBD<br />

Using the data file developed in section 4.9, all the <strong>an</strong>alysis in section 4.7 was repeated<br />

<strong>an</strong>d definition characteristics were calculated through the same methods. Selection <strong>of</strong> our<br />

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