ICSTI Statement on Nanotechnology - Forfás
ICSTI Statement on Nanotechnology - Forfás
ICSTI Statement on Nanotechnology - Forfás
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Elan Corporati<strong>on</strong> develops and markets pharmaceuticals and<br />
drug-delivery technology. Its pharmaceutical business focuses <strong>on</strong><br />
neurology, pain management, dermatology, antibiotics, and<br />
autoimmune diseases. Its drug delivery business developed and<br />
patented the NanoCrystal system for formulating poorly soluble<br />
compounds as nanoparticles, thereby increasing their surface area<br />
and their solubility. There are currently two pharmaceutical<br />
products that have been commercialised incorporating<br />
NanoCrystal technology, with several additi<strong>on</strong>al product launches<br />
anticipated over the next two years. The NanoCrystal technology<br />
is protected by 85 issued US patents and 48 pending patents.<br />
Elan has established manufacturing scale capability for<br />
pharmaceutical products formulated using their proprietary<br />
NanoCrystal technology at their Irish development and<br />
manufacturing site in Athl<strong>on</strong>e. A drug in nano-form can be<br />
incorporated into comm<strong>on</strong> dosage forms, including tablets,<br />
capsules, inhalati<strong>on</strong> devices, sterile forms for injecti<strong>on</strong>, with the<br />
potential for substantial improvements to clinical performance.<br />
Aerogen Ireland Ltd is a subsidiary of Aerogen Inc based in<br />
California, a specialty pharmaceutical company developing inhaled<br />
drug products to advance the treatment of respiratory disorders<br />
and chr<strong>on</strong>ic diseases. The company is focused <strong>on</strong> efficient,<br />
c<strong>on</strong>venient delivery of aerosolised drugs to the lungs, and<br />
through the lungs to the blood stream. Its Irish operati<strong>on</strong>s are<br />
based in Galway where the core business is in the manufacture of<br />
pulm<strong>on</strong>ary drug delivery devices. Aerogen’s range of current and<br />
future products includes specialised nebulisers and breathactivated<br />
inhalers for marketing by Aerogen, as well as novel<br />
inhalers for leading pharmaceutical and biotechnology companies.<br />
Aerogen have recently established a small three-pers<strong>on</strong> team,<br />
based in Galway, to formulate drugs as nanoparticles for aerosol<br />
delivery. The company has stated that the recent changes to Elan<br />
in this country have led to the availability of some highly skilled<br />
individuals.