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Drugs, Pharmaceutics - Gobizkorea

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Chemical & Textiles<br />

<strong>Drugs</strong>, <strong>Pharmaceutics</strong><br />

part8<br />

Gelatin s Viscosity is a<br />

function of pH, temperature,<br />

and concentration. The<br />

viscosity of gelatin solution is<br />

lowest at the isoelectric point.<br />

If gelatin solution is heated, its<br />

viscosity decreases. The rate<br />

of decrease in viscosity<br />

affected noticeably by pH and<br />

heating temperature.<br />

- Viscosity Breakdown<br />

Gelatin in solution is subject to<br />

thermal degradation or<br />

enzymatic hydrolysis. The<br />

extent of thermal degradation<br />

is a fuction of temreature, time<br />

and PH and is minimal at near<br />

neutral pH.<br />

- pH<br />

pH does not affect the<br />

fundamental properties of<br />

gelatin. Gelatin PH is normally<br />

controlled to 5 to 6 in order to<br />

minmize the growth of<br />

bacteria.<br />

- Isoelectric Point<br />

This is the pH of a gelatin<br />

solution at which the gelatin<br />

molecules have zero net<br />

charge and therby show no<br />

net migration on application of<br />

an electric field. The swell of<br />

gelatin lowered at isoelectric<br />

point.<br />

Cetirizine HCl, Pancreatin,<br />

Glimepiride(2mg),<br />

Solidification, Controlled<br />

release, Enteric coated, New<br />

API, New Excipient<br />

ACETAMINOPHEN<br />

Specification<br />

Active Substance Described in<br />

a Pharmacopoeia(Ph.Eur.)<br />

Acetaminophen T/M for<br />

Chewable Tablet has not have<br />

been described in European<br />

Pharmacopoeia such USP, EP.<br />

We internally set up<br />

190<br />

DASAN MEDICHEM Co., Ltd.<br />

10, Wasan-ri, Dogo-myeon,<br />

Asan-si, Chungcheongnam-do<br />

336-912, Korea<br />

T +82-41-543-5311<br />

F +82-41-543-5314<br />

http://www.dspharm.com<br />

http://eblog.gobizkorea.com/1999<br />

-a0111<br />

dasan@dspharm.com<br />

product : Acetaminophen,<br />

Ibuprofen, Roxithromycin,<br />

Clarithromycin, Azithromycin,<br />

Simethicone, Roxatidine<br />

Acetate HCl,<br />

Pseudoephedrine HCl

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