Prof. Dr. Joachim Kirsch Institute for Anatomy and Cell ... - HBIGS

PUBLICATIONS (10 selected publications since 2000):
Nawrotzki, R., Kirstein, M., Knöpfle, K., Kirsch, J. 2004. Alternative splicing of gephyrin
controls the collybistin-mediated targeting to the cell surface. (submitted)
Schmidt, E., Corvey, C., Janista, C., Karas, M., Kirsch, J., Kuhse, J. The glycine receptor is
involved in the regulation of the RAFT/mTOR signaling pathway. (submitted)
Xiang, S., Nassar, N., Kirsch, J., Schindelin, H. Insights into Collybistin Function from the
Crystal Structure of the Cdc42-Collybistin II Complex. (submitted)
von Boyen, G.B., Steinkamp, M., Geerling, I., Reinshagen, M., Schäfer, K-H., Adler, G.,
Kirsch, J. Enteric glia secrete neurotrophic factors upon stimulation with proinflammatory
cytokines: a possible role for gut protection during inflammation (submitted)
von Boyen, G.B., Steinkamp, M., Reinshagen, M., Schäfer, K., Adler, G., Kirsch, J. 2004.
Proinflammatory cytokines increase GFAP expression in enteric glia. Gut 53: 222–228.
Giesemann, K., Schwarz, G., Mendel, R.R., Nawrotzki , R., Kirsch, J., Jockusch, B. 2003.
Complex formation between the postsynaptic scaffolding protein gephyrin profilin and MENA:
a possible link to the microfilament system. J. Neurosci 23: 8330-8339.
Fuhrmann, J.C., Kins, S., Rostaing, P., El Far, O., Kirsch, J., Sheng, M., Triller, A., Betz, H.,
Kneussel, M. 2002. Gephyrin interacts with Dynein light chains 1 and 2, components of
motor protein complexes. J. Neurosci 22: 5393-5402.
Jess, U., El Far, O., Kirsch, J., Betz, H. 2002. Interaction of the C-terminal region of the rat
serotonin transporter with MacMARCKS modulates 5-HT uptake regulation by protein kinase
C. Biochem Biophys Res Commun 294: 272-279.
Kins, S., Betz, H., Kirsch, J. 2000. Collybistin, a newly identified brain-specific GEF, induces
submembrane clustering of gephyrin. Nat Neurosci 3: 22-29.
Ramming, M., Kins, S., Werner, N., Hermann, A., Betz, H., Kirsch, J. 2000. Diversity and
phylogeny of gephyrin: tissue-specific splice variants, gene structure, and sequence
similarities to molybdenum cofactor-synthesizing and cytoskeleton-associated proteins. Proc
Natl Acad Sci USA 97: 10266-10271.
Simburger, E., Plaschke, M., Kirsch, J., Nitsch, R. 2000. Distribution of the receptoranchoring
protein gephyrin in the rat dentate gyrus and changes following entorhinal cortex
lesion. Cereb Cortex 10: 422-432.
Reviews
von Boyen, G.B., Reinshagen, M., Steinkamp, M., Adler, G., Kirsch, J. 2002. Enteric
nervous plasticity and development: dependence on neurotrophic factors. J Gastroenterol
37: 583-588.
von Boyen, G.B., Reinshagen, M., Steinkamp, M., Adler, G., Kirsch, J. 2002. Gut
inflammation modulated by the enteric nervous system and neurotrophic factors. Scand J
Gastroenterol 37: 621-625.