PD Dr. Renate Voit Molecular Biology of the Cell II German ... - HBIGS

PD Dr. Renate Voit
Molecular Biology of the Cell II
German Cancer Research Center (DKFZ)
69120 Heidelberg, Germany
Phone: +49-(0)6221-42 1425
Fax: +49-(0)6221-42 3467
E-mail: r.voit@dkfz.de
26/10/1956, Fichtelberg
CURRICULUM VITAE
1999 – present Senior scientist, Division Molecular Biology of the Cell II, German Cancer
Research Center, Heidelberg
2000 Habilitation at the Faculty of Biology, University of Heidelberg,
Venia Legendi (Molecular Biolology)
1997 – 1999 Habilitationsstipendium (DFG)
1991 – 1997 Research Associate with I. Grummt, German Cancer Research Center,
Heidelberg
1988 – 1990 Postdoctoral research in the Institute of Zoology, University of Munich
1984 – 1987 Graduate work, University of Munich, Dr.rer.nat. (1987)
1978 – 1984 Studies in Biology, Universities of Erlangen and Munich, Diploma (1984)
FIELDS OF INTEREST
Transcriptional and posttranscriptional control of RNA polymerase I transcription; Cell cycle
and gene expression; Mammalian Cdc14B phosphatase; small molecule inhibitors;
Mammalian Sirtuins;
CURRENTLY FUNDED PROJECTS
Cdc14 small molecule inhibitors (HGF, translational project)

PUBLICATIONS (10 selected publications):
Denissov, S., van Driel, M., Voit, R., Hekkelman, M., Hulsen, T., Hernandez, N., Grummt, I.,
Wehrens, R. and Stunnenberg, H. (2007). Identification of novel TBP-binding sites and
general factor repertoires. EMBO J. 20:1075-1080.
Arai, S., Miyake, K., Voit, R., Nemoto, S., Wakeland, E.K., Grummt, I. and Miyazaki, T.
(2007). Death-effector domain-containing protein DEDD is an inhibitor of mitotic
Cdk1/cyclin B1. Proc. Natl. Acad. Sci. USA. 104:2289-2294.
Ford, E., Voit, R., Liszt, G., Magin, C., Grummt, I. and Guarente, L. (2006). Mammalian Sir2
homolog SIRT7 is an activator of RNA polymerase I transcription. Genes Dev.
20:1075-1080.
Meraner, J., Lechner, M., Loidl, A., Goralik-Schramel, M., Voit, R., Grummt, I. and Loidl, P.
(2006). Acetylation of UBF changes during the cell cycle and regulates the interaction
with RNA polymerase I. Nucleic Acids Res. 34:1798-1806.
Percipalle, P., Fomproix, N., Cavellan, E., Voit, R., Krüger, T., Thyberg, J., Scheer, U.,
Grummt, I. and Östlund-Farrants, A. (2006). The chromatin remodelling complex
WSTF-SNF2H interacts with nuclear myosin 1 and has a role in RNA polymerase I
transcription. EMBO Rep. 7:525-530.
Prisco, M., Maiorana, A., Guerzoni, C., Calin, G., Calabretta, B., Voit, R., Grummt, I. and
Baserga, R. (2004). Role of pescadillo and upstream binding factor in the proliferation
and differentiation of murine myeloid cells. Mol. Cell. Biol. 24:5421-5433.
Hassepass, I., Voit, R. and Hoffmann, I. (2003). Molecular mechanism mediating cdc25
depending entry into S-phase. J. Biol. Chem. 278:29824-29829.
Voit, R. and Grummt, I. (2001). Phosphorylation of UBF at serine 388 is required for
interaction with RNA polymerase I and activation of rDNA transcription. Proc. Natl.
Acad. Sci. USA 98:13631-13636.
Ciarmatori, S., Scott, P. H., Sutcliff, J. E., McLees, A., Alzuherri, H. M., Dannenberg, J.-H., te
Riele, H., Grummt, I., Voit, R. and White, R. J. (2001). Overlapping functions of the
pRb family in the regulation of rRNA synthesis. Mol. Cell. Biol. 21:5806-5814.
Muth, V., Nadaud, S., Grummt, I. and Voit, R. (2001). Acetylation of TAF I 68, a subunit of TIF-
IB/SL1, activates RNA polymerase I transcription. EMBO J. 20:1353-1362.

SUPERVISED DISSERTATION
Sonia Ciarmatori, PhD (2001) The functional role of pRb and p130 in RNA polymerase I
transcription
Current occupation: unknown