CANCER CHEMOTHERAPY ACENAPHTHENE ... - Cancer Research

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47
COLCHICINE —¿ EFFECT ON NORMAL GROWTH
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770 Fleischmann, W. and Ullyot, G. E. STUDIES ON
COLCHICINE DERIVATIVES. II. EFFECT ON III-
TOTIC ACTIVITY OF THE CORNEAL EPITHELIUM.
Cancer, N. Y., 1950, 3: 130-133. 9 refs.
Colchicine and 6 derivatives were investi
gated. Colchicine was the most toxic. The
less toxic compounds were in general less
effective on mitosis with the exception of
trimethylcolchicinic acid methyl ether,
which arrested mitosis significantly at
1 / 100 of the LD50.
771
Gaulden, H. E. and Carlson, J. G. CYTOLOGICAL
EFFECTS OF COLCHICINE ON THE GRASSHOPPER
NEUROBLAST IN VITRO WITH SPECIAL REFERENCE TO
THE ORIGIN OF THE SPINDLE. Exp. Cell. Res.,
1951, -i\416-433. pi. 34 refs.
772 Grampa, G. AZIONE CITOPLASMATICA DELLA COL-
CHICINA NEL FEGATO NORMALE E IN RIGENERAZIONE
SPERIMENTALE. [EFFECT OF COLCHICINE ON THE
PROTOPLASM OF CELLS OF THE NORMAL AND REGENER
ATING LIVER.] Studia ghisler., 1949, U 261-
268. 15 refs. Abstracted in: Excerpta med.,
Sect. 5, 1952, 5: No. 2389.
773
Harven, E. de and Gerard, P, SUR L'ACTIVITÉ
MITOTIOUE DES MYÉLQCYTES EOSINOPHILES CHEZ
LE RAT COLCHICINISE. [MITOTIC ACTIVITY OF
EOSINOPHIL MYELOCYTES IN RATS AFTER COLCHI
CINE ADMINISTRATION.] C. rend. Soc. biol.,
1953, 147: 911-913. 4 refs.
774 Havas, L. J. SUR QUELQUES PROBLEMES DE
CROISSANCE ÉTUDIES ÀL'AIDE DE LA COLCHICINE
CHEZ LES PLANTES ET CHEZ LES ANIMAUX. [SOME
PROBLEMS OF GROWTH STUDIED IN PLANTS AND
ANIMALS BY MEANS OF COLCHICINE.] Ann. Soc.
se. méd. nat. Bruxelles, 1948, 1: 57-77.
66 refs. Abstracted in: Excerpta med., Sect.
5, 1949, 2: No. 2885. A lecture reviewing
the literature of "...the reactions of plants
to Colchicine, particularly with respect to
phytocarcinomas and hormonal action; it is
also concerned...with the effect of colchicine
on growth in rats, on the development
of Rana temporaria and on the phenomenon
of the 'bridal gown' in Rhodeus amarus."
-Excerpta med.
775 Hayas, L. J. and Kahan,,J. REACTIONS DES VERS
A SOIE (BOMBYX MQRI) A LA COLCHICINE, LA
PODOPHYLLINE ET A L'ACENAPHTENE. [THE RE
ACTION OF'SILK WORMS (BOMBYX MORI) TO
COLCHICINE, PODOPHYLLIN AND ACENAPHTHENE.]
Arch. biol. hung., 1948, 18: 117-131.
55 refs. Depending on the doses used,
Colchicine and podophyllin either inhibit
or stimulate the hatching of silk worms.
Acenaphthene always inhibits hatching.
Colchicine increases the length and weight
of the silk worm body.
776 Isler, H. QUELQUES EXPERIENCES DE LABORATOIRE
SUR LA COLCHICINE ET LA PODOPHYLLINE. [LA
BORATORY EXPERIMENTS WITH COLCHICINE AND
PODOPHYLLIN.] Schweiz, med. Wschr., 1950,
80: 438.
777
Jenkins, W. R. and Bohren, B. B. THE EFFECT
OF COLCHICINE ON THE SEMINIFEROUS TUBULES OF
FOWL TESTIS. Poultry Sc., 1949, 28: 650-652.
Abstracted in: Chem. Abstr., 19507-44: 1606d.
779
Lehmann, F. E. and Hadorn, H. VERGLEICHENDE
WIRKUNGSANALYSE VON ZWEI ANTIMITOTISCHEN
STOFFEN, COLCHICIN UND BENZOCHINON, AM TUBIFEX-
EI. [COMPARATIVE ANALYSIS OF THE ACTION OF
TWO ANTIMITOTIC AGENTS, COLCHICINE AND BENZO-
QUINONE, ON THE EGG OF TUBIFEX]. Helvet.
physiol. pharm. acta, 1946, 4: 11-42. 34 refs.
780Lettre, H. and Albrecht, M. 'ÜBERDIE ABHÄNGIG
KEIT DER COLCH1CINWIRKUNG VON DER ADENOSINTRI-
PHOSPHORSÄURE. [DEPENDENCE OF COLCHICINE ACTION
ON ATP.] Naturwissenschaften, 1951, 38: 547-
548. 8 refs. Colchicine at a concentration of
0.04 /«.gper ml produced mitosis inhibition of
fibroblast cultures after 1 hr. This effect
was not observed until 4 hours later, when
ATP in concentration of 1 mg per ml was added
to the former agent. The experiment demonstra
ted that the inhibitory action of Colchicine
is antagonized by ATP present in the cell.
781
Levine, M. THE ACTION OF COLCHICINE ON CELL
DIVISION IN HUMAN CANCER, ANIMAL, AND PLANT
TISSUES. Ann. N. York Acad. Sc., 1951, 51:
1365-1408. Discussion: p. 1406-1408. 78 refs.
Abstracted in: Chem. Abstr., 1951, 45: 5803h.
A review of the literature and a report of
the author's own work dealing with: (1) ef
fect of colchicine on root-tips of Allium
cepa: (2) action of colchicine on advanced
neoplasms in man; and (3) colchicized plant
tissues as influenced by x-rays.
782
Lüscher, M. HEMMT ODER FORDERT COLCHICIN DIE
ZELLTEILUNG IM REGENERIEREDEN SCHWANZ DER
XENOPUS-LARVE? [DOES COLCHICINE INHIBIT OR
PROMOTE CELL DIVISION IN THE REGENERATING
TAIL OF THE XENOPUS LARVA?] Rev. Suisse
Zool., 1946, 53: 481-486. 7 refs.
783
LUscher, M. DIE HEMMUNG DER REGENERATION DURCH
COLCHICIN BEIM SCHWANZ DER XENOPUS-LARVE UND
IHRE ENTWICKLUNGSPHYSIOLOGISCHE WIRKUNGSANALYSE.
[THE INHIBITION OF THE REGENERATION OF THE
TAIL OF THE XENOPUS-LARVA BY COLCHICINE AND
AN ANALYSIS OF ITS MODE OF ACTION IN THE LIGHT
OF DEVELOPMENTAL PHYSIOLOGY,] Helvet. physiol.
pharm. acta, 1946, 4: 465-494. 21 refs.
784 Malinsky, J. and Lang, B. EFFETS DE LA COLCHI
CINE, DE L'ISOCOLCHICINE ET DE L'AMIDE DE
COLCHICINE SUR LA MITOSE. [EFFECTS OF COLCHI
CINE, ISOCOLCHICINE AND COLCHICAMIDE ON MI
TOSIS.] C. rend. Soc. biol., 1951, 145:
613-616. 5 refs.
785 Malinsky, J. and Lang, B. HYPERPLASIE DU FOIE
DE RAT APRES HEPATECTOMIE PARTIELLE ET IN
FLUENCE DES CORPS COLCHICINÉS SUR CELLE-CI.
[HYPERPLASIA OF THE RAT LIVER AFTER PARTIAL
HEPATECTOMY AND THE INFLUENCE 0F COLCHICINE
THEREON.] C. rend. Soc. biol., 1951, 145:
609-612.
Matkó L. and Haraszti, A. THE EFFECT OF CHRONIC
CHOLCHICINE INTOXICATION ON THE BLOOD COUNT AND
ON THE BONE MARROW. Acta morph. hung., 1952,
2: 219-230. 2 pi. 9 refs. "...gradually
progressing secondary aplastic bone marrow is
brought about which finally leads to the com
plete termination of myelopoesis, as well as
to the fibrous transformation of the bone
marrow."
778
Kantner, H. DER EINFLUSS DES COLCHICINS AUF DIE
ZELLTEILUNG LEBENDER AMPHIBIEN. [INFLUENCE OF
COLCHICINE ON THE CELL DIVISION OF LIVING
AMPHIBIA]. Zschr. Anat. Entw., 1950, 115:
273-286. 15 refs. Abstracted in: Chem. Abstr.
1951, 45: 5328b.
787 Meier, R. MODIFICACIONES ESPECIFICAS DEL CRE
CIMIENTO CELULAR. [SPECIFIC CHANGES IN CELL
GROWTH.] An. med. dr., Barcel., 1948, 23:
221-233. Abstracted in: Excerpta med., SEct.
2, 1949, 2: No. 2170. A lecture.