Bone mineralisation during osteoporosis
Bone mineralisation during osteoporosis
Bone mineralisation during osteoporosis
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Osteoporosis<br />
• Osteoporosis is a skeletal disorder where bone strength is<br />
reduced resulting in increased risk of fracture. Every 3 minutes<br />
someone has a fracture due to <strong>osteoporosis</strong>.<br />
• Cost to European Economy: €17 billion annually<br />
• Aging population worldwide. 30% of people will have a hip<br />
fracture by 90yrs (IOF). In Ireland, 3-fold increase in hip<br />
fractures since 1990<br />
• Affects most commonly post- menopausal women (14-18%<br />
risk v 3-6% in males)<br />
• Detected clinically by measuring bone quantity (BMD) using<br />
DEXA scanning. Treated clinically with drugs (eg:<br />
bisphosphonates) which prevent osteoclast activity & maintain<br />
bone density
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