Bone mineralisation during osteoporosis
Bone mineralisation during osteoporosis
Bone mineralisation during osteoporosis
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Tissue Engineering Focus<br />
• Biomaterial scaffolds<br />
- Collagen-glycosaminoglycan (tailored)<br />
- Collagen-ceramic composites<br />
• Cells<br />
– Cell types<br />
• Mesenchymal stem cells<br />
• Amniotic fluid-derived stem cells<br />
• Osteoblasts<br />
• Chondrocytes<br />
• Smooth muscles cells, endothelial cells<br />
• Cell signalling<br />
- Bioreactors<br />
- role of biophysical stimuli in regulating stem cell<br />
differentiation and tissue formation<br />
- Genes & Growth factors<br />
Tissue Engineering<br />
Triad<br />
Angiogenesis<br />
+VEGF<br />
+Ephrin- B2<br />
+SMC & ECs<br />
+ Hypoxia<br />
+ Flow perfusion<br />
Funded by: SFI, HRB, IRCSET, Enterprise Ireland & European Research Council (FP7)
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