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Handbook Part 2 - International Mycological Association

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1145-1345 Meeting Room 3-5<br />

Symposium 37: Advanced Cellular Imaging and Micromanipulation<br />

Chair: Nick Read (UK) / Rosa Mouriño-Pérez (Mexico)<br />

In recent years, there has been a renaissance in the use of imaging and micromanipulation techniques in cell biology.<br />

Major innovations and developments in microscope technologies (e.g. confocal microsocopy, 2-photon microscopy),<br />

live-cell imaging, fluorescent probes (e.g. GFP), electron microscopy (e.g. field emission EM, electron tomography),<br />

and cellular micromanipulation techniques (e.g. laser tweezers, laser microdissection) are having a big impact in<br />

fungal biology. This Symposium aims to highlight some of the most recent examples of these exciting new<br />

developments in cellular imaging and micromanipulation.<br />

1145-1205 IS1 - 0833<br />

In Vivo Imaging of the Dynamics of the Microtubular Cytoskeleton of Neurospora crassa Wild Type, ropy-1, ropy-3<br />

and nkin<br />

Rosa Mouriño-Pérez (Mexico)<br />

1205-1225 IS2 - 0486<br />

Visualization of the endocytic pathway and endosomal structures in the filamentous fungus Aspergillus oryzae<br />

Yujiro Higuchi (Japan)<br />

1225-1245 IS3 - 0727<br />

NETWORK structure and dynamics of fungal mycelia<br />

Dan Bebber (UK)<br />

1245-1305 PS1 -<br />

Advanced microscopic imaging coupled with X-ray absorption spectroscopy to characterise fungal metal and<br />

mineral transformations<br />

Geoff Gadd (UK)<br />

1305-1320 PS2 -<br />

Optical tweezer micromanipulation of filamentous fungi<br />

Nick Read (UK)<br />

1145-1345 Hall C<br />

Symposium 38: Fungal Pigments and Virulence<br />

Chairs: Josh Nosanchuk (USA) / Beatriz L. Gomez (UK)<br />

Melanins pigments are enigmatic compounds that are produced by organisms in all biological kingdoms, including a<br />

wide variety of pathogenic bacteria, fungi, and helminthes. Melanin synthesis has been associated with virulence for<br />

a variety of pathogenic microbes and this phenomenon has been extensively examined in fungal pathogens. Dr.<br />

Beatriz Gomez- Giraldo will describe the identification of melanin in Candida albicans and other pathogenic fungi.<br />

The third major talk will be by Dr. Josh Nosanchuk who will discuss the clinical significance of fungal melanization. The<br />

purpose of this symposium is to provide broad insights into the role of melanins in fungal pathogenesis.<br />

1145-1215 IS1 - 1006<br />

Clinical impact of fungal melanization<br />

Josh Nosanchuk (USA)<br />

1215-1245 IS2 - 1009<br />

The darker side of Candida albicans and Paracoccidioides brasiliensis<br />

Beatriz L. Gomez (UK)<br />

1245-1315 PS1 - 0803<br />

Production and utilization of fungal pigment in textile dyeing<br />

Karuppan Perumal (India)<br />

1315-1345 PS2 - 0340<br />

Peroxisomal acetyl-CoA is essential for appressorial melanization, and virulence in Magnaporthe.<br />

Naweed Naqvi (Singapore)<br />

1145-1345 Halls A&B<br />

Symposium 39: Biosynthetic Gene Clusters for Fungal Secondary Metabolites<br />

Chairs: Nancy Keller (USA) / Marc Stadler (Germany)<br />

Secondary metabolites (extrolites) are of utmost importance in higher fungi. They constitute essential features of high<br />

ecological, pathological, and taxonomic significance and exert great detrimental as well as beneficial influence on<br />

human civilization. Only recently has it become possible to study their biogenesis at the molecular level, due to the<br />

availability of molecular methods and the templates provided by genomic approaches. While most of the research<br />

has so far been done on industrial & agriculturally important fungi (in particular, pharmaceutical and mycotoxin -<br />

producing ascomycetes), it now appears feasible to study large taxonomic groups in an attempt to evaluate<br />

evolutionary aspects of secondary metabolite biosynthesis. In the symposium, different chemical types of metabolites<br />

(e.g. polyketides, alkaloids) and different producer organisms will be presented to provide an overview on our current<br />

understanding of fungal secondary metabolitsm and future perspectives in the study of these compounds.<br />

249

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