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Toxoplasmosis in cats - IMD Berlin

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Evidence of a toxoplasma <strong>in</strong>fection<br />

<strong>in</strong> humans<br />

<strong>Toxoplasmosis</strong> <strong>in</strong> humans can be detected by<br />

the doctor by analys<strong>in</strong>g a blood sample. The<br />

sample is analysed for antibodies aga<strong>in</strong>st toxoplasma<br />

gondii.<br />

Women who wish to become pregnant should<br />

undergo a medical exam<strong>in</strong>ation for toxoplasmosis<br />

antibodies.<br />

Women that have already suffered from toxoplasmosis<br />

and possess protective antibodies are<br />

safe from renewed <strong>in</strong>fection.<br />

How can humans protect themselves from<br />

toxoplasmosis?<br />

It is not necessary to remove the cat or to stay<br />

away from it, as contact with <strong>cats</strong> as such is not<br />

dangerous but only the contact with cat faeces.<br />

1. Gloves should be worn <strong>in</strong> occupations that<br />

can lead to contact with cat faeces (clean<br />

<strong>in</strong>g of the cat litter box, garden work).<br />

2. Daily clean<strong>in</strong>g and dis<strong>in</strong>fection of the cat litter<br />

box with hot water (more than 70°C) reduces<br />

the risk of <strong>in</strong>fection.<br />

3. Vegetables should be thoroughly washed<br />

before consumption and fruit peeled if<br />

possible.<br />

4. Hands should be washed thoroughly after<br />

prepar<strong>in</strong>g meat.<br />

5. The consumption of raw or <strong>in</strong>sufficiently<br />

cooked meat or sausages (especially pork,<br />

goat and lamb) and untreated milk should<br />

be avoided.<br />

We offer the follow<strong>in</strong>g laboratory tests:<br />

For the cat:<br />

from the faeces:<br />

flotation<br />

from the blood:<br />

antibody attestation for toxoplasmosis<br />

IgG and IgM<br />

For humans:<br />

from the blood:<br />

antibody attestation for toxoplasmosis<br />

IgG and IgM<br />

Additional diagnostic exam<strong>in</strong>ations if necessary<br />

Institut für Mediz<strong>in</strong>ische Diagnostik MVZ GbR<br />

(Institutes for Medical Diagnostics)<br />

Nicolaistr. 22, 12247 Berl<strong>in</strong><br />

Telephone: 030-77001-0<br />

Surgery stamp<br />

We are always pleased to provide you with further<br />

<strong>in</strong>formation.<br />

Institute for Veter<strong>in</strong>ary Medical Diagnostics<br />

Institut für Veter<strong>in</strong>ärmediz<strong>in</strong>ische Diagnostik<br />

Nicolaistraße 22, 12247 Berl<strong>in</strong><br />

Tel.: 030 – 77001 222 , Fax: 030 – 77001 332<br />

<strong>Toxoplasmosis</strong><br />

<strong>in</strong> <strong>cats</strong><br />

SERVICE


The pathogen<br />

Toxoplasma gondii is a s<strong>in</strong>gle-celled parasite and is<br />

found <strong>in</strong> all warm blooded animals and <strong>in</strong> humans.<br />

Def<strong>in</strong>itive hosts are only <strong>cats</strong> that discharge the<br />

<strong>in</strong>fectious eggs (oocysts) with their faeces. Apart<br />

from the oocysts there are two further <strong>in</strong>fectious<br />

phases, an active propagation phase and a<br />

dormancy period <strong>in</strong> tissue cysts. Both are present<br />

<strong>in</strong> the def<strong>in</strong>itive as well as <strong>in</strong> the <strong>in</strong>termediate host.<br />

Intermediate hosts are small animals of prey such<br />

as mice, however all other mammals are able to<br />

become <strong>in</strong>termediate hosts.<br />

<strong>Toxoplasmosis</strong> <strong>in</strong> <strong>cats</strong><br />

Cats become <strong>in</strong>fected with toxoplasmosis ma<strong>in</strong>ly<br />

by <strong>in</strong>gest<strong>in</strong>g rodents or by feed<strong>in</strong>g on raw meat.<br />

Cats that are solely domestic can also become<br />

<strong>in</strong>fected if they are fed for example raw meat.<br />

Cl<strong>in</strong>ical symptoms rarely appear <strong>in</strong> <strong>cats</strong>. Occasionally<br />

slight diarrhoea is noticed <strong>in</strong> affected <strong>cats</strong>.<br />

As a rule affected <strong>cats</strong> discharge oocysts with the<br />

faeces <strong>in</strong> their surround<strong>in</strong>gs only <strong>in</strong> the event of a<br />

primary <strong>in</strong>fection. The oocysts only become<br />

<strong>in</strong>fectious after 2-4 days <strong>in</strong> the environment. The<br />

discharge lasts for a maximum of 10 days. Should<br />

the oocysts be <strong>in</strong>gested by warm blooded animals<br />

(e.g. mice) or humans they can become<br />

<strong>in</strong>fected.<br />

Other mammals do not discharge toxoplasma<br />

gondii. They can however become carriers of<br />

tissue cysts as <strong>in</strong>termediate hosts. The most common<br />

source of <strong>in</strong>fection for humans is the meat of<br />

the affected animals. Dogs also do not discharge<br />

toxoplasma oocysts with their faeces and are<br />

therefore not carriers of toxoplasmosis.<br />

Does my cat constitute a risk of <strong>in</strong>fection?<br />

The risk of <strong>in</strong>fection for a cat can be estimated by<br />

an analysis of a faeces specimen and a blood<br />

sample:<br />

Should the blood test as well as two tests of the<br />

faeces with<strong>in</strong> a 14 day <strong>in</strong>terval prove negative<br />

then the cat is most probably not yet <strong>in</strong>fected with<br />

toxoplasma. Measures to prevent <strong>in</strong>fection can be<br />

taken by e.g. keep<strong>in</strong>g the cat <strong>in</strong>doors and not<br />

feed<strong>in</strong>g it fresh food.<br />

Persons at risk (pregnant women or immuno-suppressed<br />

persons) are to avoid contact with cat<br />

faeces should there be evidence of oocysts <strong>in</strong> the<br />

faeces.<br />

The discharge period of oocysts is most probably<br />

over when antibodies are detected dur<strong>in</strong>g the<br />

blood test.<br />

How can the cat be protected from<br />

toxoplasmosis?<br />

In pr<strong>in</strong>ciple <strong>cats</strong> should not be fed with raw meet<br />

or slaughterhouse waste.<br />

A roam<strong>in</strong>g cat that catches and eats mice is<br />

however not protected from an <strong>in</strong>fection.<br />

Toxoplasma – oocysts <strong>in</strong> the faeces<br />

<strong>Toxoplasmosis</strong> <strong>in</strong> humans<br />

Humans also do not discharge oocysts. They can<br />

however, like mammals, become carriers of<br />

tissue cysts as <strong>in</strong>termediate hosts. In most cases<br />

assimilation however does not ensue from<br />

contact with <strong>cats</strong> or their excrements. The most<br />

common source for <strong>in</strong>fection is the <strong>in</strong>gestion of<br />

raw meet (tartar, raw m<strong>in</strong>ced pork, raw sausage)<br />

followed by fruit and vegetables that are<br />

contam<strong>in</strong>ated with oocysts. Insufficient hygiene<br />

dur<strong>in</strong>g garden work may also lead to assimilation<br />

of oocysts.<br />

A primary <strong>in</strong>fection with toxoplasma normally<br />

does not lead to symptoms <strong>in</strong> a healthy person.<br />

Occasionally fever attacks and flu-like symptoms<br />

can occur (i.a. swell<strong>in</strong>g of the lymph node,<br />

fatigue, exhaustion, headaches).<br />

Should primary <strong>in</strong>fection with toxoplasma occur<br />

dur<strong>in</strong>g pregnancy, the fetal <strong>in</strong>fection risk and the<br />

cl<strong>in</strong>ical pattern depend on various factors. The<br />

later the woman gets <strong>in</strong>fected dur<strong>in</strong>g the course<br />

of pregnancy the higher the probability of a<br />

fetal <strong>in</strong>fection. The earlier <strong>in</strong>fection takes place<br />

dur<strong>in</strong>g pregnancy the more severe the consequences<br />

are for the unborn child.

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