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Pascale BARBERGER-GATEAU - Isped

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<strong>Pascale</strong> <strong>BARBERGER</strong>-<strong>GATEAU</strong><br />

Date of birth: 11 August 1954<br />

Marital status: Married, four children<br />

Nationality: French<br />

Professional address:<br />

Research Center INSERM U897, University Bordeaux Segalen,<br />

146 rue Léo-Saignat, 33076 Bordeaux Cedex, France<br />

Tel : + 33 5 57 57 15 96 Fax : + 33 5 57 57 14 86<br />

E-mail : <strong>Pascale</strong>.Barberger-Gateau@isped.u-bordeaux2.fr<br />

Diplomas and qualifications<br />

1995 Qualification in Public Health by the French National Medical Council<br />

1987 PhD in Epidemiology, University of Bordeaux<br />

1981 Master degree « Methods in Informatics and Statistics”, University of Bordeaux<br />

1981 University Diploma « Health and Development », University of Bordeaux<br />

1979 Maîtrise Biologie Humaine (= Master first degree) “Biomathematics, Statistics, Medical<br />

Informatics”, University of Bordeaux<br />

1980 Medical Doctorate (MD), University of Bordeaux<br />

Other university training:<br />

Intensive course "Approach and Methods in Community Health", Department of Social and Preventive<br />

Medicine, University of Montréal, Canada, 7-18 June 1982.<br />

Employment history<br />

- since 2009<br />

Associate professor at the Department of Food Science and Nutrition of Laval University, Québec<br />

(Canada),<br />

- since 2005<br />

Beneficiary of an interface contract between the French National Institute of Health and Medical<br />

Research (INSERM) and the University Hospital of Bordeaux<br />

- since 2003<br />

Head of the team « Nutritional epidemiology» at the INSERM department U593 “Epidemiology,<br />

Public Health and Development” and then at the Research Centre INSERM U897 « Epidemiology and<br />

Biostatistics » since 2008<br />

- since 1985<br />

Maître de Conférences des Universités-Praticien Hospitalier (assistant professor and hospital<br />

practitioner) in Epidemiology at the Institute of Public Health, Epidemiology and Development (ISPED)<br />

of the University Victor Segalen Bordeaux 2, and at the Department of Medical Information of the<br />

University Hospital of Bordeaux<br />

. 1982 - 85:<br />

University and Hospital Assistant in Mathematics, Statistics and Medical Informatics :<br />

- Laboratory of Epidemiology (Pr. SALAMON) at the University Bordeaux 2.<br />

- Department of Medical Information at the University Hospital of Bordeaux<br />

. 1980 - 82:<br />

- Associate - assistant in Mathematics, Statistics and Medical Informatics at the University<br />

Bordeaux 2 from 01/11/1980 to 30/09/198,.<br />

- Assistant at the University Hospital of Bordeaux in Cardiovascular Radiology (Services Pr. BESSE<br />

and Dr. MARTIN) from 1/1/1981 to 30/09/1982<br />

. Training period abroad:<br />

01/10/1977 – 30/03/1978: Institute of Cardiology (head Dr. A. Moisan), Laval Hospital, Québec City<br />

(Canada).<br />

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Main research activities:<br />

My main research field concerned the epidemiology of aging for 30 years, with a particular interest in<br />

Alzheimer’s disease and its consequences on Activities of Daily Living. I presently lead an original research<br />

on nutritional protective or risk factors of Alzheimer’s disease based on the French PAQUID and Three-City<br />

cohort studies.<br />

Co-principal investigator with J.F. Dartigues of the PAQUID (QUID sur les Personnes Agées)<br />

epidemiological study since its origin in 1987.<br />

Associate investigator for the Bordeaux site of the Three-City Study since its origin in 1998 and<br />

responsible for the nutritional aspects.<br />

Principal investigator of the COGINUT (COGnition, anti-oxidants, fatty acids: Interdisciplinary<br />

approach of the role of NUTrition in brain aging) research program funded by the French National<br />

Agency for Research (2006-2010).<br />

Participation to scientific journals<br />

Member of the editorial boards of Disability and Rehabilitation (since 1997), the European Journal of<br />

Ageing (2004-2011), future associate editor of the Journal of Alzheimer’s disease (starting in 2013).<br />

Reviewer for N Engl J Med, Am J Epidemiol, Arch Gen Psy, Int J Obesity, Nature Clin Pract Neurol, Nutr<br />

Neurosci, Eur J Epidemiol, Br J Nutr, J Nutr Health Aging, Int J Geriatr Psychiatr, Am J Clin Nutr, J Alz Dis…<br />

Main general functions and expertise<br />

Member of the National University Council 46-01 (Public Health) from 1997 to 2003.<br />

Member of the scientific board of the Carnot Institute LISA (Lipids for Industry and Health).<br />

Representative of the Bordeaux University at the Institute for Research on Human Nutrition in Aquitaine<br />

(IRNHA) since 2009 and president of the Scientific Committee<br />

Scientific coordinator for France of the international Institute of Nutrition Aquitaine Quebec (INAQ)<br />

created in 2009.<br />

Member of the Danone Institute, French Society of Gerontology and Geriatrics (SFGG), Association of<br />

French-speaking Epidemiologists (ADELF), Association for the Development of Epidemiology in<br />

Aquitaine (ADEA, board member), French Society for the Study of Lipids (SFEL), Group Lipids and<br />

Nutrition (GLN, board member), Fonds français pour l'alimentation et la santé.<br />

Five major recent publications (out of 157 in Medline)<br />

Raffaitin C, Féart C, Le Goff M, Amieva H, Helmer C, Akbaraly TN, Tzourio C, Gin H, Barberger-<br />

Gateau P: Metabolic syndrome and cognitive decline in French elders. The Three-City study.<br />

Neurology 2011, 76 518-525.<br />

Feart C, Samieri C, Rondeau V, Amieva H, Portet F, Dartigues JF, Scarmeas N, Barberger<br />

Gateau P: Adherence to the Mediterranean Diet, Cognitive Decline and Risk of Dementia<br />

JAMA, 2009, 302: 638-648<br />

Dubois B, Feldman H, Jacova C, Cummings J, Dekosky S, Barberger-Gateau P, Delacourte A,<br />

Frisoni G, Fox N, Galasko D et al: Revising the definition of Alzheimer's disease: a new lexicon.<br />

Lancet Neurol 2010, 9: 1118-1127<br />

Lambert J-C, Heath S, Even G, Campion D, Sleegers K, Hiltunen M, Combarros O, Zelenika D,<br />

Bullido MJ, Tavernier B, Letenneur L, Bettens K, Berr C, Pasquier F, Fievet N, Barberger-<br />

Gateau P et al.: Genome-wide association study identifies variants at CLU and CR1 associated<br />

with Alzheimer's disease. Nat Genet, 2009, 41: 1094-U68<br />

Raffaitin C, Gin H, Empana JP, Helmer C, Berr C, Tzourio C, Portet F, Dartigues JF, Alperovitch<br />

A, Barberger-Gateau P: Metabolic syndrome and risk for incident Alzheimer's disease or<br />

vascular dementia: the Three - City study. Diabetes Care, 2009, 32: 169-174<br />

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