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2007 Final Program - Society of Behavioral Medicine

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<strong>2007</strong> SBM Annual Meeting & Scientific Sessions March 21-24, <strong>2007</strong> FINAL PROGRAM<br />

Rapid Communications Posters Friday, March 23, <strong>2007</strong> • 6:30 PM-8:00 PM • Poster Session C<br />

reported more realistic control perceived greater effectiveness in<br />

coping with chemotherapy (p= .029). Furthermore, and as expected,<br />

results indicated that realistic control was positively correlated<br />

to optimism (p=.003). Coping efficacy and optimism were also<br />

positively related (p=.012). In a follow-up study with these women<br />

two years later, use <strong>of</strong> positive reframing was positively correlated to<br />

post-traumatic growth (p=.054). These results suggest that realistic<br />

and unrealistic control perceptions may be important determinants<br />

<strong>of</strong> effective coping with treatment for breast cancer. Implications<br />

and limitations are discussed.<br />

CORRESPONDING AUTHOR: Steve G. Caloudas, BA, Houston<br />

Baptist University, Houston, TX, 77056; scaloudas@yahoo.com<br />

3452<br />

DEPRESSION, ANXIETY AND NATURAL KILLER CELL<br />

CYTOTOXICITY IN MEN TREATED FOR PROSTATE<br />

CANCER<br />

Eric S. Zhou, BS, 1 Frank J. Penedo, PhD, 1 , 2 Lara Traeger, MS, 1<br />

Mikal Rasheed, BS, 1 Bonnie Blomberg, PhD, 3 Mary Anne Fletcher,<br />

PhD, 3 Neil Schneiderman, PhD 1 and Michael H. Antoni, PhD 1 , 2<br />

1<br />

Psychology, University <strong>of</strong> Miami, Coral Gables, FL; 2 Sylvester<br />

Comprehensive Cancer Center, University <strong>of</strong> Miami, Coral Gables,<br />

FL and 3 Microbiology and Immunology, University <strong>of</strong> Miami,<br />

Coral Gables, FL.<br />

Treatment for prostate cancer (PC) is <strong>of</strong>ten associated with the<br />

development <strong>of</strong> side effects including urinary, bowel and sexual<br />

dysfunction and compromises in general quality <strong>of</strong> life. Research<br />

indicates that natural killer cell cytotoxicity (NKCC) is negatively<br />

associated with both anxiety and depression in the general<br />

population, but there has been minimal work conducted with<br />

PC patients. The current study examined relationships among<br />

depression, anxiety and NKCC in men treated for PC. Participants<br />

were men (N=125) who had received either radical prostatectomy<br />

or radiation therapy for localized PC, with an average age <strong>of</strong> 63.9<br />

years (SD=7.2), average yearly income <strong>of</strong> $50,570 (SD=$44,300)<br />

and an average <strong>of</strong> 14.0 years <strong>of</strong> education (SD=3.4). Severity <strong>of</strong><br />

depression was assessed using the Beck Depression Inventory,<br />

anxiety with the Pr<strong>of</strong>ile <strong>of</strong> Mood States and NKCC using a Cr51<br />

release assay against the k562 cell line with a 1:1 target to effector<br />

cell ratio. Results indicated that greater NKCC was negatively and<br />

significantly associated with less depression (r=-.21) and less anxiety<br />

(r=-.23; both ps

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