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Regulation of gene expression in eukaryotes

Regulation of gene expression in eukaryotes

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Activation model <strong>of</strong> GAL <strong>gene</strong>s <strong>in</strong> yeast.<br />

III. Post-transcriptional control<br />

Alternative polyadenylation and splic<strong>in</strong>g <strong>of</strong> the human CACL <strong>gene</strong> <strong>in</strong><br />

thyroid and neuronal cells.<br />

A. Alternative splic<strong>in</strong>g - Some messages undergo<br />

alternate splic<strong>in</strong>g depend<strong>in</strong>g on what tissue they<br />

are located <strong>in</strong>. The regulation is at the level <strong>of</strong><br />

snRNP production.<br />

– Some pre-mRNAs can be<br />

– Controlled by RNA b<strong>in</strong>d<strong>in</strong>g splic<strong>in</strong>g factors that commit<br />

splic<strong>in</strong>g <strong>in</strong> a particular way<br />

Calciton<strong>in</strong><br />

<strong>gene</strong>-related<br />

peptide<br />

5

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