The neurotoxic cascade in the ischemic penumbra
The neurotoxic cascade in the ischemic penumbra
The neurotoxic cascade in the ischemic penumbra
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<strong>neurotoxic</strong> <strong>cascade</strong> <strong>in</strong> <strong>the</strong> <strong>ischemic</strong> <strong>penumbra</strong><br />
De Keyser et al., 1999<br />
15<br />
-O, 18 FDG, 18 F-MISO,<br />
11<br />
C-FMZ, 18F-CPFPX<br />
PLA2<br />
BBB disruption, endo<strong>the</strong>lial disturbances<br />
Cell <strong>in</strong>filtration<br />
Cell necrosis<br />
Tissue remodel<strong>in</strong>g, angiogenesis,