4-Aminopiperidine Building Blocks - Dottikon
4-Aminopiperidine Building Blocks - Dottikon
4-Aminopiperidine Building Blocks - Dottikon
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4-<strong>Aminopiperidine</strong> <strong>Building</strong> <strong>Blocks</strong><br />
Core Hydrogenation to N-Substituted 4-<strong>Aminopiperidine</strong> <strong>Building</strong> <strong>Blocks</strong><br />
Typical building blocks<br />
Benzyl-<br />
NH2<br />
N<br />
R<br />
DOTTIKON ES, with its production site in <strong>Dottikon</strong> (Aargau, Switzerland), is specialized in hazardous chemical reactions and focuses on the exclusive synthesis of fine<br />
chemicals for the pharmaceutical and chemical industry worldwide. The product range of DOTTIKON ES includes active pharmaceutical ingredients (APIs) and<br />
pharmaceutical intermediates as well as in-house-developed, high-value industrial chemicals.<br />
Contact<br />
Europe<br />
<strong>Dottikon</strong> Exclusive Synthesis AG<br />
P.O. Box, 5605 <strong>Dottikon</strong>, Switzerland<br />
Tel +41 56 616 81 11, Fax +41 56 616 81 20<br />
info@dottikon.com, www.dottikon.com<br />
Methoxyethyl-<br />
O<br />
NH2<br />
N<br />
United States of America<br />
<strong>Dottikon</strong> ES America, Inc.<br />
803 W. Trenton Avenue, Suite 1, Morrisville, PA 19067, USA<br />
Tel +1 215 295 2295, Fax +1 215 295 2577<br />
info.us@dottikon.com, www.dottikon.com<br />
Methoxypropyl-<br />
O<br />
NH2<br />
N<br />
Alkoxycarbonyl-<br />
O<br />
NH2<br />
N<br />
OAlkyl<br />
� Combination of<br />
DOTTIKON's<br />
core technologies<br />
� High-pressure<br />
� Hazardous<br />
Reactions<br />
� Multi-ton production<br />
facilities<br />
� Tailor-made<br />
4-aminopiperidines<br />
on request
4-<strong>Aminopiperidine</strong> <strong>Building</strong> <strong>Blocks</strong> for API Structures<br />
Illustrative Examples of Potential use in Patent-Protected Structures<br />
R<br />
R<br />
X<br />
X<br />
R<br />
DOTTIKON ES, with its production site in <strong>Dottikon</strong> (Aargau, Switzerland), is specialized in hazardous chemical reactions and focuses on the exclusive synthesis of fine<br />
chemicals for the pharmaceutical and chemical industry worldwide. The product range of DOTTIKON ES includes active pharmaceutical ingredients (APIs) and<br />
pharmaceutical intermediates as well as in-house-developed, high-value industrial chemicals.<br />
Contact<br />
Europe<br />
<strong>Dottikon</strong> Exclusive Synthesis AG<br />
P.O. Box, 5605 <strong>Dottikon</strong>, Switzerland<br />
Tel +41 56 616 81 11, Fax +41 56 616 81 20<br />
info@dottikon.com, www.dottikon.com<br />
O<br />
N<br />
H<br />
R<br />
H<br />
N<br />
N<br />
O<br />
O N O<br />
United States of America<br />
<strong>Dottikon</strong> ES America, Inc.<br />
803 W. Trenton Avenue, Suite 1, Morrisville, PA 19067, USA<br />
Tel +1 215 295 2295, Fax +1 215 295 2577<br />
info.us@dottikon.com, www.dottikon.com<br />
NH 2<br />
N<br />
R<br />
X<br />
R R<br />
R<br />
R H<br />
R R<br />
N<br />
H<br />
H<br />
N<br />
O N<br />
N<br />
O<br />
OAlkyl<br />
R