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Endometrioma With Calcification Simulating a Dermoid - Journal of ...

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<strong>Endometrioma</strong> <strong>With</strong> <strong>Calcification</strong> <strong>Simulating</strong> a <strong>Dermoid</strong><br />

Pelvic sonography depicted a normal uterus<br />

and normal left ovary. In the right adnexa, there<br />

was a 4 × 3 × 3.5-cm mass, which showed<br />

enhanced through-transmission, and a fluidfluid<br />

level consisting <strong>of</strong> echogenic fluid layering<br />

with hypoechoic fluid. This was thought to be a<br />

fat-fluid level (Figure 1A). It also showed an 11-<br />

mm discrete calcification (Figure 1B). The mass<br />

was surrounded by normal-appearing ovarian<br />

parenchyma. These findings were thought to be<br />

diagnostic <strong>of</strong> a cystic teratoma. Magnetic resonance<br />

imaging was recommended for confirmation<br />

<strong>of</strong> the sonographic diagnosis because MRI is<br />

recommended to characterize complex masses<br />

for definitive diagnosis at our institution.<br />

Magnetic resonance imaging showed a normal<br />

uterus and normal left ovary containing physiologic<br />

follicles. There was a 4 × 3 × 3.5-cm mass in<br />

the right ovary. This mass showed high signal<br />

intensity on conventional and fat-suppressed<br />

T1-weighted images (Figure 2, A and B). High signal<br />

intensity was also seen on fat-suppressed T2-<br />

weighted images (Figure 2C). Bright signal<br />

intensity not suppressed by fat is indicative <strong>of</strong><br />

blood products. Normal ovarian parenchyma<br />

was seen surrounding the mass on fat-suppressed<br />

T2-weighted images (Figure 2C). The calcification<br />

within the mass that was well<br />

visualized on sonography (Figure 1B), was seen<br />

as a focus with low signal intensity on all the MRI<br />

sequences (Figure 2, A–D). A fluid-fluid level was<br />

seen in the mass, with partial shading indicative<br />

<strong>of</strong> old blood, on T2-weighted images (Figure 2, C<br />

and D). This fluid-fluid level did not show fat signal<br />

intensity on MRI and was determined to be<br />

related to old and new blood products. On MRI,<br />

this was not thought to be fat-fluid level. Thus,<br />

with analysis <strong>of</strong> the signal intensities on all the<br />

sequences, the mass was thought to be an<br />

endometrioma containing an unusual feature <strong>of</strong><br />

a discrete calcification.<br />

The patient then had a laparoscopic removal <strong>of</strong><br />

the mass. Histopathologic findings <strong>of</strong> the resected<br />

endometrioma revealed extensive fresh and<br />

old blood with hemosiderin-laden macrophages.<br />

The calcification was located in the fluid portion<br />

<strong>of</strong> the mass. There was no solid component in<br />

this cystic mass at histopathologic examination.<br />

A marblelike calcification fell out when the mass<br />

was cut open after removal.<br />

Discussion<br />

Although endometriomas can have variable<br />

sonographic appearances, certain sonographic<br />

criteria are useful in making a definitive diagnosis.<br />

Most experts 1,3–5 have agreed on one common<br />

sonographic feature <strong>of</strong> diffuse dispersion <strong>of</strong><br />

low-level echoes within a cystic mass. Patel et al 2<br />

addressed a set <strong>of</strong> features that would increase or<br />

decrease the likelihood ratio for the diagnosis <strong>of</strong><br />

an endometrioma. Their findings confirm that<br />

Figure 1. A, Transverse transabdominal sonogram shows a fluid-fluid level (arrow) in a cystic mass and solid ovarian tissue <strong>of</strong> normal ovarian parenchyma<br />

(arrowheads). B, Coronal endovaginal sonogram shows a cystic mass filled with diffuse low-level internal echoes and a 1.1-cm calcification (calipers).<br />

A<br />

B<br />

1238 J Ultrasound Med 2006; 25:1237–1241

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