Selco Coenzyme Q10 Leaflet - Kinetik

Coenzyme Q10
Description
Coenzyme Q10 has a quinoid structure and is therefore
also named Ubiquinone 50 or Ubidecarenone.
Coenzyme Q10 is produced by fermentation process
or in a half synthetic process, starting from tobacco
plant and Solanesol extracted out of the plant. Our
standard material is produced by bacterial fermentation
process, which is regarded as natural Coenzyme
Q10.
Coenzyme Q10 is produced in the human body and
is responsible for a wide spread range of important
biological activities. Coenzyme Q10 is a lipophilic
unique antioxidant and radical scavenger that inhibits
lipid peroxidation, lipid and protein oxidation in skin
cells and regenerates other antioxidants like tocopherol.
It occurs in very low concentrations in nearly
all organisms and it is used in nutrition and pharmaceutical
industry since many years due to its effi cacy
profi le.
Appearance
Effi cacy
Not all functions of Coenzyme Q10 in the biological
systems are known yet, but many of them. Coenzyme
Q10 functions as an electron transfer agent
in the respiratory chain. It’s presence in Leucocytes,
Keratinocytes, Fibroblasts protect these and all other
cells (as Coenzyme Q10 is ubiquitous) against very
active oxygen structures like Superoxide, Singulett-
Oxygene and Hydroxyl radicals, which are known to
contribute to the process of aging and photoaging of
the skin.
As energy transfer agent and outstanding radical
scavenger Coenzyme Q10 is known for its effi cacy
in heart therapy, neurodermatitis, psoriasis, paradonthosis,
external substitution under stress, adipositas,
immune assistance and recently against Parkinson’s
disease and breast cancer.
In dermal application it functions as antioxidant acting
in multiple ways to reduce the effects of environmental
aggression to the skin, visible in the reduction of
wrinkle depth and a decreased turnover time of epithelium.
Yellow to orange amorphous powder
INCI
Ubiquinone
Registration
CAS-No........................................................303-98-0
EINECS/ELINCS-No..................................206-147-9
Preservatives/Stabilizers
none
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Coenzyme Q10
Chemical Structure
Application concentration
Anti Age creams....................................0.01 - 0.2 %
Skin creams..........................................0.01 - 0.1 %
Body treatment.....................................0.01 - 0.05 %
Incorporation
(Source Wikipedia)
Molecular formel: C 59 H 90 O 4
In paraffi n oil it is easily soluble up to 1 % under stirring
at about 50°C.
In Phenylethanol-1 it is soluble up to 2 % under stirring
at about 50°C.
Characteristics
Toxicology
content Coenzyme Q10..........................min. 98.0 %
Water content.........................................max. 0.20 %
residue on ignition..................................max. 0.10 %
heavy metals.........................................max. 20 ppm
Non - irritating to skin and eyes
Non - toxic and non - cytotoxic
Non - phototoxic
Non mutagenic
Coenzyme Q10 is used as dietary supplement as
well. The product is classifi ed as “safe” in the view of
its toxicological evaluation.
Storage & Shelf life
Coenzyme Q10 should be stored in a dark place at
temperatures below 30°C.
Longer exposure to UV-rays should be avoided. In
sealed containers Coenzyme Q10 has a stability of
about 3 years.
Application
Because of its unique functions Coenzyme Q10 is an
attractive active ingredient for many cosmetic applications.
In the dermis it is reduced from Ubiquinone
to Ubiquinol, the active antioxidant.
Coenzyme Q10 prevents very effective oxidative
stress in human skin cells.
Furthermore, it protects from chronological and photoaging
of dermal fi broblasts. It reduces the negative
effects of photoaging which is shown by reducing the
depth of wrinkles.
Selco Wirkstoffe Vertriebs GmbH
Straßburg 16
69483 Wald-Michelbach / Germany
Telefon +49 6207 922 80
Telefax +49 6207 922 810
www.gfn-selco.de
info@gfn-selco.de
Leafl et_6034_e01
06.04.2011/sb
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