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Deep Vein Thrombosis: Diagnosis & Treatment Reginald E. Smith ...

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Major bleeding rates<br />

3.50<br />

3.00<br />

2.50<br />

RR 0.80 (95% CI: 0.69–0.93)<br />

2.71<br />

p=0.003 (sup)<br />

RRR<br />

20%<br />

RR 0.93 (95% CI: 0.81–1.07)<br />

3.11<br />

p=0.31 (sup)<br />

3.36<br />

% per year<br />

2.00<br />

1.50<br />

1.00<br />

0.50<br />

0.00<br />

D110 mg BID D150 mg BID Warfarin<br />

Connolly SJ., et al. NEJM published online on Aug 30th 2009.<br />

DOI 10.1056/NEJMoa0905561<br />

322 / 6,015 375 / 6,076 397 / 6,022<br />

Dabigatran etexilate is in clinical development and not licensed for<br />

clinical use in stroke prevention for patients with atrial fibrillation

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