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Deep Vein Thrombosis: Diagnosis & Treatment Reginald E. Smith ...

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Rivaroxaban<br />

Brand name Xarelto ® , Bayer<br />

High oral bioavailability<br />

(>80%)<br />

Onset of action 2-4 hours<br />

Half-life 9-12 hours<br />

Prophylactic Dose 10 mg qd<br />

<strong>Treatment</strong> Dose 20 mg daily<br />

Primarily renal elimination<br />

(66%), remainder feces p<br />

glycoprotein<br />

No laboratory monitoring<br />

required<br />

No dosage adjustment for<br />

gender, age, extreme<br />

body weight

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