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Dr Bhawna Sirohi’s CV<br />
CURRICULUM VITAE<br />
PERSONAL DETAILS:<br />
Name:<br />
Bhawna Sirohi<br />
Telephone Mobile 0091 (0) 99300 33980<br />
Email<br />
Bhawna.sirohi@btinternet.com<br />
GMC Registration number Full Medical 4758297 (Specialist register of Medical<br />
Oncology)<br />
Delhi Medical Council 45709<br />
Mahrashtra Medical Council 2012/10/2916<br />
Date of birth September 13, 1968<br />
Permanent address A-162 Defence Colony, Mawana Road<br />
Meerut, UP. <strong>India</strong><br />
EDUCATION:<br />
1991 MBBS<br />
I: Government Medical College, Nagpur University, Mahrashtra, <strong>India</strong><br />
II-III: Lala Lajpat Rai Medical College (LLRM), Meerut University, UP, <strong>India</strong><br />
Overall 1 st rank aggregate in all three MBBS examinations<br />
Distinction in Anatomy, Biochemistry, Forensic Medicine, Obs & Gynae<br />
Certificate of honours in Pathology, Pharmacology, Surgery<br />
Gold Medal in Anatomy, Obs & Gynae.<br />
1994 DCH –Diploma in Child Health<br />
Lala Lajpat Rai Medical College (LLRM), Meerut University, UP, <strong>India</strong><br />
1997 Completed training in Medical Oncology at Tata <strong>Cancer</strong> Hospital, Mumbai<br />
2007 European School of Medical Oncology accreditation<br />
2009 Certificate of Eligibility for Specialist Registration in Medical Oncology, On<br />
Specialist register of General Medical Council, UK<br />
2009 Affiliate Member Royal College of Physicians, London<br />
CURRENT APPOINTMENT:<br />
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Dr Bhawna Sirohi’s CV<br />
May 2012 –continuing<br />
Consultant Medical Oncologist –GI & Breast Unit<br />
Tata Memorial Centre<br />
Mumbai-400012<br />
PREVIOUS APPOINTMENTS:<br />
July 2010 – April 2012<br />
Head of Medical & Haemato-Oncology<br />
Artemis <strong>Cancer</strong> Centre<br />
Artemis Healthsciences, Sector -51<br />
Gurgaon and Delhi, <strong>India</strong><br />
Artemis is a 300-bedded tertiary care private hospital in the NCR region. Since I<br />
joined, following have been initiated /implemented within the oncology department<br />
1. Optimised daycare facility with oncology trained nurses and an admixture lab<br />
with laminar flow.<br />
2. Regular courses for the nurses in handling chemotherapy, infection control,<br />
hand hygiene and care of central venous access devices.<br />
3. Monthly cancer awareness programmes and clinical screening camps in the<br />
nearby villages and resident welfare associations through the hospital and<br />
NICCI (New <strong>India</strong> <strong>Cancer</strong> Charity Initiative)<br />
4. Complimentary palliative care program in collaboration with Cansupport<br />
5. Joint site-specific clinics for Breast, GI, Gynaecological and head & neck<br />
cancers.<br />
6. Home Care program for end of life care, palliative care, administration of<br />
infusions, injections and blood sampling prior to chemotherapy.<br />
7. DNB inspection for medical oncology<br />
8. NABH re-accreditation for medical oncology<br />
9. Patient support group meetings.<br />
10. Antibiotic stewardship committee to rationalise the use of antibiotics within<br />
the hospital<br />
11. Prospectively maintained database which reports to the Haryana and IRCH<br />
<strong>Cancer</strong> registry<br />
12. Clinical trials unit.<br />
October 2009 –June 2010 Max <strong>Cancer</strong> Centre, Max Healthcare, New Delhi<br />
Max is tertiary care hospital with 8 hospitals all over National capital region. This<br />
was my first appointment on return from UK as Director and Chief consultant in<br />
Medical Oncology (Pan-Max). I had been involved in setting up of the medical<br />
oncology unit from Jan 2009 onwards with weekly tele and video-conferences at two<br />
sites (Saket and Patparganj). I set up an international standard (designed on the basis<br />
of Royal Marsden MHRA standard facility with support room, changing and clean<br />
room) laminar flow facility for chemotherapy admixing for the safety of the nurses<br />
and patients ay both the sites. This was manned by oncology pharmacists. I was<br />
instrumental in getting the unit thorough NABH accreditation and was working<br />
towards planning for JCI accreditation. During my period at Max, I was a member of<br />
the Hospital ethics committee, institutional review board, consumer advocacy board,<br />
Hospital infection control committee, central pharmacy and therapeutics committee.<br />
June 2009 –September 2009 Guy’s and St Thomas’ NHS foundation Trust<br />
London<br />
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Dr Bhawna Sirohi’s CV<br />
I joined Guys and St Thomas’ as locum consultant medical oncologist within the<br />
breast, GI and Lung unit. I also did a breast cancer clinic once a week at Kings<br />
college Hospital. This helped me develop crucial ties with both the institutions.<br />
I was closely involved in the teaching of specialist registrars and senior house<br />
officers.<br />
May 2008 – June 2009 Addenbrookes hospital, Hills Road, Cambridge, CB2 2QQ<br />
I joined as consultant medical oncologist within the GI and melanoma unit. I was<br />
chief and principal investigator on trials in GI and skin cancers. I was involved in the<br />
teaching of specialist registrars, senior house officers and medical students from<br />
various colleges in Cambridge.<br />
Feb 1998-May 2008 Royal Marsden NHS Foundation Trust, Chelsea and Sutton,<br />
London<br />
I joined as a research fellow in the Haemato-Oncology Unit with Prof Ray Powles in<br />
February 1998 and within a year, I was fully responsible for the day to day running of<br />
the unit, coordination of clinical trials (from Phase I to III), recruitment of research<br />
nurses, fellows, data managers and doctors. During my tenure at the Royal Marsden, I<br />
continued working at senior level of a specialist registrar /honorary consultant while<br />
my accreditation based on experience with the UK Joint Royal College of physicians<br />
training board was ongoing. I also worked at Parkside Oncology clinic, Wimbeldon as<br />
honorary Consultant from Jan 2004 onwards.<br />
Consultants I have worked closely with:<br />
Prof Ray Powles, Prof Daniel Catovsky, Dr Jennifer Treleaven (Haemato-oncology),<br />
Prof Alan Horwich, Prof David Dearnaley, Dr Robert Huddart, Dr Chris Parker<br />
(Urology), Dr Mary O’Brien (Lung , Breast), Prof David Cunningham, Dr Geoffery<br />
Chong (GI/Lymphoma), Prof Ian Smith, Dr Stephen Johnston, Dr Mark Allen<br />
(Breast), Prof Martin Gore, Dr Michelle Harrison, Dr Ana Montes (Gynae/Renal and<br />
Melanoma), Dr Frank Saran, Dr Diana Tait, Dr Gill Ross (Clinical Oncology), Dr<br />
Julia Riley, Dr Andrew Davies (Palliative Care), Prof Peter Mortimer (Dermatology),<br />
Dr Jervoise Andreyev, Dr Martin Benson (Gastroenterologists), Dr Clare Shaw<br />
(Dietician), Dr Craig Carr (ITU), Ms Shelley Dolan (ITU).<br />
The Royal Marsden NHS Foundation Trust is one of the largest comprehensive<br />
cancer centre in Europe with over 40,000 patients from the UK and abroad seen each<br />
year. This is a recognized training centre for Medical Oncology trainees and has<br />
about 300 beds. It is located on two sites- Sutton and Fulham Road. I have worked as<br />
an SpR within various Medical Oncology firms which are part of the RMH training<br />
programme. I have been involved with seeing new patients, second opinions as well<br />
as routine follow-ups. I have been continually involved with the busy out-patient and<br />
in-patient ward work throughout my training.<br />
I have gained a broad base of experience in treating all the major tumour types. My<br />
job has involved in working at <strong>more</strong> than 1 site and also at District General Hospitals<br />
like St Helier hospitals, Epsom and Kingston Hospital. At St Helier hospital, I<br />
particularly enjoyed teaching medical students while doing the lung cancer clinic. I<br />
have worked to develop my communication skills throughout my training including<br />
two skills courses.<br />
Throughout my period at the Royal Marsden Hospital, I gained experience in all<br />
aspects of clinical trial work, including trial design for investigator initiated studies,<br />
3
Dr Bhawna Sirohi’s CV<br />
liaison with pharmaceutical companies for sponsored studies, statistical<br />
considerations and both scientific and ethical committee approval, in addition to<br />
active patient accrual, treatment and monitoring. I have analysed and presented<br />
scientific and clinical data at national and international meetings. I published <strong>more</strong><br />
than 70 peer-reviewed papers and numerous abstracts during this period along with<br />
oral and poster presentations throughout at international meetings. I have played an<br />
active role in medical education and clinical management and undertaken regular<br />
bedside and tutorial teaching of doctors, nurses and pharmacists. I have made regular<br />
case presentations at postgraduate teachings and grand rounds.<br />
Dec 1996-Jan 1998 Department of Medical Oncology<br />
Tata <strong>Cancer</strong> Hospital, Parel, Mumbai, <strong>India</strong><br />
I worked under the supervision of Dr SH Advani and Prof PM Parikh.<br />
Aug 1996 -Dec 1996 Medical Oncology<br />
Indraprastha Apollo Hospital, New Delhi, <strong>India</strong><br />
Indraprastha Apollo Hospital is a 600 bedded hospital based in Delhi. I worked here<br />
with Dr Rakesh Chopra as a senior registrar and gained further experience in Medical<br />
oncology. As this was a new set-up, I trained the nurses and residents to handle and<br />
give chemotherapy - to take care of infusion pumps, catheters, nightly feedings and<br />
parenteral nutrition in patients receiving chemotherapy.<br />
Gap of 3 months (May 1996- July 1996): Personal reasons<br />
Feb 1996-Apr 1996 Medical Oncology<br />
Rungta Hospital, Jaipur, <strong>India</strong><br />
I worked in this private institute as a Consultant for a short while and was in charge of<br />
day to day care of Medical oncology patients.<br />
Sept 1994-Jan 1996 Medical Oncology, Tata <strong>Cancer</strong> Hospital, Mumbai,<br />
Consultants I have worked with:<br />
Dr SH Advani (Haemato-oncology and Solid tumours); Dr T Saikia (BMT,<br />
Lymphomas); Dr PM Parikh (Lung cancer, Gynaecologic <strong>Cancer</strong>s), Dr K Nadkarni<br />
(GI cancers, Sarcomas); Dr VR Pai (Head and Neck <strong>Cancer</strong>);Dr CN Nair (Academic<br />
Haematology);Dr S Pai (Leukaemia and Lymphomas);Dr R Gopal (Breast,<br />
Myeloma);<br />
Dr P Kurkure (Paediatric tumours)<br />
Tata Memorial hospital is a 700 bedded tertiary cancer centre which caters to the<br />
South-East Asia draining patients from Middle-East and the <strong>India</strong>n sub-continent.<br />
This was a resident job, hence I stayed in hospital accommodation on the 10 th floor of<br />
the building and the main oncology wards were on the 7 th and 11 th floor. This was<br />
mainly for the purpose of the on-calls. During this period I gained experience in<br />
giving chemotherapy for various malignancies, management of complications due to<br />
chemotherapy and reporting of bone marrow slides. Besides being responsible for all<br />
admissions and inpatient management of our 60 adult and paediatric beds, I did the<br />
out-patient clinics daily which caters to solid tumours and haematological<br />
malignancies, and had a daily attendance of about 60-70 patients. The training<br />
involved rotation with the above mentioned consultants in various fields of Oncology.<br />
4
Dr Bhawna Sirohi’s CV<br />
July 1992-Aug 1994 Lala Lajpat Rai Medical College (LLRM),<br />
Meerut, UP, <strong>India</strong><br />
During this period, I completed by DCH.<br />
Apr 1991-Apr 1992<br />
Intern<br />
Prof Usha Sharma MD<br />
Lala Lajpat Rai Medical College (LLRM),<br />
PL Sharma Hospital<br />
Meerut, UP, <strong>India</strong>.<br />
PROFESSIONAL BODIES MEMBERSHIP<br />
International<br />
Secretary of the EBMT Nuclear Accident Committee (since 2001- )<br />
American Society of Clinical Oncology (since 2001- )<br />
American Society of Haematology (since 2000- )<br />
European School of Medical Oncology (since 2006- )<br />
Early Breast <strong>Cancer</strong> Trialists Collaborative Group (2006, 2010)<br />
Scientific Advisor, International Myeloma Foundation (2002-2006)<br />
Member, Acute Leukaemia Working Party, European Blood and Marrow<br />
Transplantation (EBMT) Group (2002-2004)<br />
Chronic Leukaemia Working Party of EBMT (Since 2002- )<br />
Multiple Myeloma Working sub-Committee of EBMT (since 2002-2009)<br />
Stem Cell Trialists Collaborative Group (2002-2007)<br />
European Haematology Association (EHA) (since 2001- )<br />
International Advisory Panel on Fungus Infections, Pfizer Limited (2001-2005)<br />
UK<br />
United Kingdom Myeloma Forum Clinical Trials committee (2002-2003)<br />
British Medical Association (since 2002-2008)<br />
British Society for Blood and Marrow Transplantation (2001-2004)<br />
Association of <strong>Cancer</strong> Physicians, UK (since 2002-2009)<br />
Pan-Thames purchasing BMT Consortium (since 2001-2004)<br />
Leukaemia/Myeloma tumour working Group- South West London <strong>Cancer</strong> Network<br />
(2002-2004)<br />
HICC (Hospital Infection Control Committee) Royal Marsden (2001-2003)<br />
JACIE accreditation committee, Royal Marsden (2002-2003)<br />
Stem cell Users group (2001-2004)<br />
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Dr Bhawna Sirohi’s CV<br />
Department of Health interdisciplinary Group on clinical care and service configuration<br />
following a radiation accident (since 2008- )<br />
Department of Health Steering Committee Member, for guidance on management of<br />
radiation accidents (since 2008- )<br />
<strong>India</strong><br />
Member, <strong>India</strong>n Medical Association (since 1992- )<br />
Life Member, <strong>India</strong>n Cooperative Oncology network (ICON since 2000- )<br />
Life Member, <strong>India</strong>n Society of Medical and Paediatric Oncology (since 2010- )<br />
Member, <strong>India</strong>n Association of Palliative Care (since 2010- )<br />
Member, <strong>India</strong>n Society for Study of Pain (since 2010- )<br />
Chairman, ICMR Task force for cancer guidelines on colorectal cancer<br />
Secretary, ICMR Task force for cancer guidelines on Gastric cancer<br />
Secretary, ICMR Task force for cancer guidelines on Multiple Myeloma<br />
Charitable Trusts association<br />
Committee Member: David Adams Leukaemia Fund (2007-2010)<br />
Management committee member, Can Support (since 2010- )<br />
Founder President, New <strong>India</strong> <strong>Cancer</strong> Charity Initiative NICCI (since 2010- )<br />
Patron, Voice of victims Campaign (since 2011- )<br />
Advisor- Indo-Canadian <strong>Cancer</strong> Research Foundation<br />
Journals /Books<br />
Editor –<strong>India</strong>n Journal of Medical and Paediatric Oncology (IJMPO)<br />
Editor –Health Positive<br />
Reviewer for The Lancet, Annals of Oncology, IJMPO, <strong>India</strong>n Journal of <strong>Cancer</strong>, JCRT<br />
Institution –Artemis /Max<br />
Member, Institutional review Board<br />
Member, Independent Ethics Committee<br />
Chairman, Care of Patients group for JCI accreditation<br />
Member, Consumer advocacy Board<br />
Member, Medical audit Committee (since 2010- )<br />
Member, Antibiotics stewardship committee<br />
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Dr Bhawna Sirohi’s CV<br />
Editor, Artemis e- journal<br />
TEACHING/EDUCATION<br />
International Collaboration<br />
Steering secretary for <strong>India</strong>n Cooperative Oncology Network: Phase III trial of<br />
Erythropoietin in patients with cervical cancer<br />
Service d’hematologie, Nantes, France: with Prof Jean-Luc Haroussaeu, International<br />
Myeloma Foundation<br />
International Myeloma Foundation annual think-tank (US Virgin Islands)<br />
Secretary of the EBMT Nuclear Accident Committee: close collaboration with most<br />
European transplant centres, ministry of defence in UK, Health protection agency,<br />
Emergency preparedness division and Department of health. Closely involved with<br />
training courses (RCP accredited for CPD) for haematologists, emergency physicians and<br />
first responders across UK and Europe.<br />
Event organisation<br />
International Myeloma Grand round<br />
On the 14 th June 2001, The Royal Marsden Hospital, London, hosted an unusual<br />
event, an 'international grand round', aimed at exploring a new concept in the<br />
treatment of multiple myeloma, 'operational cure'. The 80 invited guests included<br />
oncologists, radiotherapists, histopathologists, representatives of the International<br />
Myeloma Foundation, members of the press, and several myeloma patients, including<br />
the two patients whose case histories were presented. Attendees: Prof Jean-Luc<br />
Harousseau, Nantes France; Prof Brain Durie, UCLA, USA, Ms Susie Novis,<br />
President IMF, Prof Greg Mundy, Texas, USA. Published in Lancet.<br />
Bone disease Grand round 15 th March 2002 for visiting Spanish Oncologists<br />
Prof Trevor Powles, Prof Ray Powles and Dr Mary O’ Brien<br />
This is your Life in collaboration with BBC and RMH staff for twin Powles brothers,<br />
2003 at the BBC studios, London.<br />
IMF Hope, Trust and effectiveness Seminar, Royal College of Physicians, London<br />
17th June 2003 for patients and carers.<br />
Education session at the annual meeting of EBMT on 28 th March 2007, Lyons on<br />
Nuclear accidents.<br />
Grand round in collaboration with Royal Brompton Hospital (Dr Simon Davies) on<br />
cardio toxicity and newer biologicals on 10 th July 2007, London.<br />
EBMT Training course on the European Approach to the Medical Management<br />
of Mass Radiation Exposure in Munich from 28 th -30 th November 2007.<br />
Education session on nuclear accidents at the annual meeting of EBMT on 1 st April<br />
2008, Florence, Italy.<br />
7
Dr Bhawna Sirohi’s CV<br />
Education session on nuclear accidents at the annual meeting of EBMT on 1 st April<br />
2009, Gotheborg, Sweden.<br />
Education session on nuclear accidents at the annual meeting of EBMT on 23rd<br />
March 2010, Vienna, Austria<br />
Onco-Cardiology CME, at Max <strong>Cancer</strong> Centre in collaboration with ISMPO, ICO,<br />
with Prof Thomas Suter 24 th April 2010.<br />
Breast <strong>Cancer</strong> Survivors workshop. Max <strong>Cancer</strong> Centre. 29 th May 2010<br />
First Brinker awardees meeting in New Delhi by NICCI on 13 th November 2010<br />
with the launch of NICCI at the British ambassador’s house.<br />
24 th ICON meeting in New Delhi on 11-13 th March 2011<br />
Education session on nuclear accidents at the annual meeting of EBMT on 5 th April<br />
2011, Paris, France.<br />
Education session on nuclear accidents at the annual meeting of EBMT on 3 rd April<br />
2012, Geneva.<br />
First European training workshop on radiation/nuclear accidents , 4 th April 2012,<br />
Geneva.<br />
UAE <strong>Cancer</strong> congress, Organsiing committee and Program coordinator for the GI<br />
session, 11-13 th Oct 2012, Dubai<br />
TMH-WCI conference, Organising secretary 19 th -21 st Oct 2012 at Tata Memorial<br />
Hospital, Mumbai<br />
Education session on nuclear accidents at the annual meeting of EBMT on 10 th April<br />
2013, London, UK<br />
<strong>India</strong>n <strong>Cancer</strong> congress 2013, Organising committee and anchor for the breast group.<br />
Noida<br />
28 th ICON 2013, Organising committee<br />
Teaching:<br />
I have always greatly enjoyed teaching, and have been involved in the undergraduate<br />
or post-graduate teaching programme<br />
1998 to 2007 Weekly teaching sessions for medical students and SHOs<br />
1999-2001 FRCR Seminars in Oncology Course<br />
1999-2002 Haematology Study Day: for SpRs<br />
8
Dr Bhawna Sirohi’s CV<br />
1999- 2007: Teaching of pharmacists and at nursing college of Royal<br />
Marsden Hospital<br />
2004 Teaching Medical students at St Helier hospital once a week<br />
2008 Teaching medical students /SpRs journal club at Addenbrookes<br />
2009 Training nurses, pharmacists and junior doctors in cancer care,<br />
chemotherapy administration<br />
Courses attended<br />
14 th October 2008 Advanced Resuscitation training<br />
17 th January 2008 ICH-GCP update course<br />
16 th -20 th July 2007 Kings Fund Management course for SpRs<br />
1 st -2 nd Mar 2007 Training course for EBMT members: “manage nuclear<br />
accidents”<br />
27 th Feb 2007 Physicians as Educators “On job teaching” RCP course<br />
8 th May 2006 RMH Communications and skills day<br />
14 th Oct 2005 Ethics and Communication Skills Day, Birbeck College,<br />
London<br />
10 th Feb 2005 Good clinical Practice and the EU directive (ICH/GCP<br />
training)<br />
1999 ASCO Clinical Trials Workshop, Flims, Switzerland<br />
MANAGEMENT EXPERIENCE<br />
Setting up a new unit<br />
I was involved with setting up of the haemato-oncology unit from the beginning at<br />
Parkside Oncology clinic with Prof Ray Powles. We celebrated 5 years in January<br />
2009. I helped set up the auto transplant programme which included setting up the<br />
infrastructure, basic training and education of the nurses, getting EBMT accreditation<br />
for the unit, setting up unit guidelines, treatment protocols and SOPs.<br />
I also set up the medical oncology at Max <strong>Cancer</strong> centre Saket and Patparganj, New<br />
Delhi and was involved from initial stages. I helped develop the concept of<br />
specialised oncology nursing and onco-pharmacy with the use of admixture lab up to<br />
international standards.<br />
Awards and Distinctions<br />
I was nominated for the Royal Marsden award for excellence by the General Manager<br />
for the rare cancer division Ms Lucie Waters in 2002. This was for my outstanding<br />
contribution to enhancing the trusts reputation in operational research and education.<br />
Nominated to be a committee member on David Adams Leukaemia Fund in 2008.<br />
Nominated to be on the Management Committee of Can Support in 2010.<br />
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Dr Bhawna Sirohi’s CV<br />
Elected to the Executive committee of <strong>India</strong>n Society of Medical and Paediatric<br />
Oncology (2011-2015)<br />
Elected to the Management committee of <strong>India</strong>n Cooperative Oncology Network (2010-<br />
2012).<br />
Nominated as a Member, Expert Panel NDTV in 2011.<br />
Nominated to be Patron for Voice of Tobacco victims in 2011.<br />
Invited to Guest edit the book on <strong>Cancer</strong> by NDTV.<br />
Invited by Elsevier to be Guest Editor (with Dr Samirun Nundy) for ECAB – adjuvant<br />
and neoadjuvant chemotherapy in GI cancers.<br />
Received the Women’s <strong>Cancer</strong> Initiative award in 2011 for charity work through<br />
NICCI.<br />
Received the LBF Visionary award for excellence in 2011.<br />
Charity /National service<br />
I have in the past been closely involved with the following charities and have helped<br />
raise money for the Royal Marsden hospital through these: David Adams Leukaemia<br />
Fund, Bud Flanagan Leukaemia Fund, Johnstone Britten Myeloma Fund, Fergus<br />
MacLay database fund.<br />
I was nominated to the management committee of Can support, a palliative care<br />
organisation in NCR in 2010<br />
I have set up NICCI- New <strong>India</strong> <strong>Cancer</strong> Charity Initiative to do clinical screening in<br />
villages in UP and also train Aaganwadi and ASHA workers in early signs of cancer<br />
and healthy lifestyle. As part of this, I also do cancer awareness talks within NCR in<br />
schools, colleges, corporate and resident welfare organisations.<br />
I am a patron of the voice of tobacco victims (VoTV) campaign.<br />
2011 - Screening camps /health awareness talks in Meerut, Daurala, New Delhi,<br />
Rewari, Dwarka, noida, Ghaziabad, Resident welfare associations of chittranjan park,<br />
saket and schools around Delhi and Meerut<br />
2012- Screening camps /health awareness talks in Bahadurgarh, Mahendragarh,<br />
Rewari, Kota (thamblou), Rajasthan<br />
Sept and Oct 2012- Involved with initial setting up of cancer registry in Rawatbhatta<br />
and Sangrur<br />
2012- Initial setting up plans of TMH, Chandigarh<br />
International Committees<br />
Throughout my period at the Royal Marsden since 2002, I have actively continued to<br />
participate in the EBMT nuclear accident committee in my role as the secretary<br />
collaboration with Department of health, Health protection agency, emergency<br />
preparedness division and ministry of defence, IAEA and WHO. We have developed<br />
a pocket guide for EBMT centres for managing patients within first 48 hours after<br />
radiation exposure. I have organised training course (RCP CPD accredited) for NHS<br />
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Dr Bhawna Sirohi’s CV<br />
trusts in UK in close collaboration with the Department of health. We are now in the<br />
process of organising a one-day European training course in London in April 2013.<br />
I have also made major contribution to the International Myeloma foundation<br />
scientific meetings in my role as their scientific advisor. I was closely involved with<br />
the workshop organised in Paris from 3 rd -8 th May 2011.<br />
Course<br />
Kings fund Management course in July 2007.<br />
Service planning<br />
UK<br />
1. Funding requests for interventions outside national or local guidelines were coordinated<br />
by the service planning department. I had regular dialogue with this<br />
department and was responsible for a number of formal requests for high-cost funding<br />
that required review by the local primary care trust.<br />
2. In order to facilitate clinical governance, I have been involved in working closely<br />
with senior pharmacists to edit and create a number of different chemotherapy<br />
protocols and proformas<br />
3. I have actively participated in the site specific group meetings for pancreatic cancer<br />
and skin cancer for the Anglia cancer network.<br />
4. I have been involved with pancreatic cancer centre review by specialised<br />
commissioning group in drafting a report at the Royal Marsden.<br />
<strong>India</strong><br />
1. Building up a referral network through educational activities and screening camps<br />
in and around Delhi<br />
2. Setting up DNB in a private institute<br />
3. Setting up site-specific approach within the clinics<br />
4. Optimising palliative care and pain control<br />
5. Ongoing audits for 30-day chemotherapy mortality, central lines, infections and<br />
adherence to protocols.<br />
6. Patient information literature<br />
Meetings attended for CPD<br />
I have attended the ASCO (May), ASH (Dec), and EBMT (March) meetings almost<br />
every year since 1998 and have previously presented at these meetings (oral, poster,<br />
poster discussion or education sessions) consistently.<br />
I also attend the <strong>India</strong>n Cooperative oncology network and ISMPO meeting alternate<br />
years. I have attended San Antonio Breast meeting in 2007, 2009 and have attended<br />
dedicated breast cancer meeting (IBCC, Paris). I attended ESMO Lugano in 2008.<br />
I have attended the Oxford overview EBCTCG in 2006 (from Royal Marsden) and<br />
2010 (20th -23rd Sept from Delhi), 2012 (from TMH).<br />
ORAL PRESENTATIONS:<br />
1. Burkitts Lymphoma - A TMH experience at XXXVI Annual Conference of<br />
ISHBT (<strong>India</strong>n Society of Haematology and Blood Transfusion) 1995, Bangalore.<br />
2. CNS directed chemotherapy in children less than or equal to 3 years of age: Use<br />
of G-CSF in maintaining dose intensity- in Feb 1997 at Madurai in ISMPO<br />
(<strong>India</strong>n Society of Medical and Paediatric Oncology).<br />
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Dr Bhawna Sirohi’s CV<br />
3. Low incidence of cardio toxicity following daunomycin and doxorubicin at a 10<br />
year follow-up in March 1997 at Annual Conference of Bombay Haematology<br />
group at Bombay<br />
4. Single centre evaluation of long term follow up of autologous stem cell<br />
transplantation for first remission adult ALL: potential for cure without excessive<br />
toxicity; Annual meeting of European Bone Marrow Transplantation (EBMT)<br />
Group, Innsbruck 6 th March 2000.<br />
5. Central nervous system relapse after stem cell transplantation (SCT) for acute<br />
leukaemia beyond first remission; Annual meeting of EBMT Group, Innsbruck 6 th<br />
March, 2000.<br />
6. CNS relapse after auto- and allo- stem cell transplant (SCT) for acute leukaemia<br />
beyond first CR. 5 th Annual Meeting of the European Haematology Association,<br />
June 2000.<br />
7. High-dose mephalan with auto-transplantation in Myeloma patients with severe<br />
renal dysfunction (GFR
Dr Bhawna Sirohi’s CV<br />
18. Results of randomised, cross over study comparing pegylated interferon with<br />
interferon-alpha2b in patients with myeloma,8 th Congress of EHA, Lyons, France<br />
15 th June 2003<br />
19. Serum free light chain assessment in myeloma patients in complete remission, 29 th<br />
EBMT Annual Meeting, Istanbul, Turkey, 21 st July 2003<br />
20. Randomised, two-period cross over study comparing quality of life and toxicity of<br />
pegylated interferon with interferon-alpha2b in patients with myeloma, 29th<br />
EBMT Annual Meeting, Istanbul, Turkey, 22nd July 2003.<br />
21. Effect of human growth hormone in haemato-oncology patients receiving<br />
intensive chemotherapy- a double-blind randomised placebo controlled trial , 23 rd<br />
joint meeting of British Endocrine societies , Brighton, 23 rd March 2004.<br />
22. Long term use of Capecitabine in patients with locally recurrent or metastatic<br />
breast cancer: concept for metronomic chemotherapy, ESMO Lugano 2008<br />
POSTER PRESENTATIONS:<br />
1. A Phase I-II study evaluating the feasibility of acute lymphoblastic leukaemiatype<br />
intensive consolidation chemotherapy (UKALL XA) after initial C-VAMP<br />
and high-dose melphalan auto transplantation at VIIth International Multiple<br />
Myeloma Workshop, Stockholm, 2nd September 1999<br />
2. The implications of compromised renal function at the time of presentation: A<br />
single centre study of 251 patients. Annual Meeting of American society of<br />
Haematology, New Orleans, December 7 1999.<br />
3. Light chain disease (LCD): A different form of myeloma compared with IgG<br />
disease. Annual Meeting of American society of Haematology, New Orleans,<br />
December 7 1999.<br />
4. High dose chemotherapy and autologous transplantation in myeloma patients<br />
aged 65 years and over: A case control comparison with younger patients. Annual<br />
Meeting of American society of Haematology, New Orleans, December 7, 1999.<br />
5. A comparison of kinetics of paraprotein clearance: Rapid decline of paraprotein<br />
after high dose melphalan (HDM) versus infusional chemotherapy (IC) in<br />
previously untreated patients with IgG multiple myeloma. Annual meeting of<br />
EBMT Group, Innsbruck 6 h March, 2000.<br />
6. High dose chemotherapy (HDT) and autologous transplantation in myeloma<br />
patients aged 65 years and over: A case control comparison with younger patients.<br />
Annual meeting of EBMT Group, Innsbruck 6 th March, 2000.<br />
7. Glomerular filtration rate (GFR) as a surrogate marker for transplant related<br />
toxicity and overall outcome in patients of multiple myeloma (MM)<br />
homogenously treated with high dose melphalan (HDM) 200mg/m 2 . Annual<br />
meeting of EBMT Group, Innsbruck 6 th March, 2000.<br />
8. Bence-Jones (BJ) Myeloma: A different form of myeloma compared to IgG and<br />
IgA myeloma. Annual meeting of EBMT Group, Innsbruck 6 th March, 2000.<br />
9. The implication of compromised and normal renal function at presentation in<br />
myeloma. Annual meeting of EBMT Group, Innsbruck 6 th March, 2000.<br />
10. Kinetics of paraprotein clearance: rapid decline of paraprotein after high-dose<br />
melphalan (HDM) compared to infusional chemotherapy in previously untreated<br />
patients with IgG myeloma. 5 th Annual Meeting of the European Haematology<br />
Association. 2000:<br />
11. Glomerular filtration rate as a surrogate marker for transplant-related toxicity and<br />
overall outcome in patients with multiple myeloma homogenously treated with<br />
13
Dr Bhawna Sirohi’s CV<br />
high-dose melphalan. 5 th Annual Meeting of the European Haematology<br />
Association. 2000:<br />
12. High-dose therapy and auto transplantation in myeloma patients aged 65 years<br />
and over: A case control comparison with younger patients. 5 th Annual Meeting of<br />
the European Haematology Association. 2000:<br />
13. Compromised renal function at presentation in myeloma – similar outcome in<br />
patients who receive high-dose therapy (HDT): A single centre study of 251<br />
previously untreated patients. British Society of Haematology, Bournemouth,<br />
2000.<br />
14. Bence Jones (BJ) myeloma: A distinct entity compared to IgG and IgA myeloma.<br />
British Society of Haematology, Bournemouth, 2000.<br />
15. Central nervous system relapses after stem cell transplantation (SCT) for acute<br />
leukaemia beyond first remission. British Society of Haematology, Bournemouth,<br />
2000.<br />
16. Central nervous system relapse after stem cell transplantation for acute<br />
leukaemia beyond first remission, Leukaemia 2000; Houston, 6 th September 2000<br />
17. Single centre evaluation of autologous stem cell transplantation in first remission<br />
followed by maintenance chemotherapy in patients with acute lymphoblastic<br />
leukaemia, Leukaemia 2000; Houston, 6 th September 2000<br />
18. High-dose melphalan and auto transplantation in myeloma patients with severe<br />
renal dysfunction (creatinine clearance 20 ml/min/m 2 ): High incidence of atrial<br />
fibrillation and treatment-related mortality. Annual Meeting of American society<br />
of Haematology, San Francisco, 5 th December 2000<br />
19. Central nervous system relapses in acute leukaemia patients transplanted beyond<br />
the first remission. Annual Meeting of American society of Haematology, San<br />
Francisco, 5 th December 2000<br />
23. Spectrum of fungal infections in patients with haematological malignancies in the<br />
last 5 years: Royal Marsden experience. Annual meeting of EBMT Group, March,<br />
2001.<br />
24. Early response to infusional chemotherapy is an independent prognostic factor in<br />
newly diagnosed IgG and IgA multiple myeloma. Annual meeting of EBMT<br />
Group, March, 2001.<br />
25. Maximal response to infusional chemotherapy prior to auto transplantation<br />
influences outcome of patients with newly-diagnosed multiple myeloma. Annual<br />
meeting of EBMT Group, March, 2001.<br />
26. High Dose melphalan and auto transplantation in myeloma patients with severe<br />
renal dysfunction: high incidence of atrial fibrillation and treatment-related<br />
mortality. Annual meeting of EBMT Group, March, 2001.<br />
27. Role of Defibrotide (Dt) and Therapeutic Plasma Exchange (TPE) in the<br />
management of transplant associated thrombotic Thrombocytopenic<br />
Purpura/Hemolytic Uremic Syndrome (TTP/HUS): a single centre Experience.<br />
Annual meeting of EBMT Group, March, 2001.<br />
28. Comparison of new patients with Bence-Jones, IgG and IgA myeloma receiving<br />
sequential therapy: the need to regard these immunologic subtypes as separate<br />
disease entities with specific prognostic criteria. Annual meeting of EBMT Group,<br />
March, 2001.<br />
20. High-Dose Melphalan with Autologous Peripheral Stem Cell Rescue in Myeloma<br />
Patients with Severe Renal Dysfunction (Creatinine Clearance
Dr Bhawna Sirohi’s CV<br />
High Incidence of Atrial Fibrillation and Treatment-Related Mortality; British<br />
society for Haematology, Harrogate , 23 rd April 2001<br />
21. Early response to infusional chemotherapy is an independent prognostic marker<br />
in newly-diagnosed IgG and IgA myeloma, British society for Haematology,<br />
Harrogate, 24 th April 2001<br />
22. High-Dose Melphalan with Autologous Peripheral Stem Cell Rescue in Myeloma<br />
Patients with Severe Renal Dysfunction (Creatinine Clearance
Dr Bhawna Sirohi’s CV<br />
35. Implications of impaired renal function at the time of initiation of infusional<br />
chemotherapy including cyclophosphomide (C-VAMP) in patients with newlydiagnosed<br />
myeloma. 28 th EBMT Annual Meeting, Montreux, Switzerland. 26 th<br />
March 2002.<br />
36. Early high-resolution computed tomography (HRCT) scans allow prompt<br />
diagnosis and efficacious treatment of invasive pulmonary aspergillosis (IPA) in<br />
immunocompromised patients with haematologic malignancies. 28 th EBMT<br />
Annual Meeting, Montreux, Switzerland. 27 th March 2002.<br />
37. Clinical implications and consequences of leukapheresis to reduce tumour burden<br />
in newly-diagnosed patients with hyperleukocytosis (HL) and acute myeloid<br />
leukaemia. 28 th EBMT Annual Meeting, Montreux, Switzerland. 26 th March<br />
2002.<br />
38. Allogeneic transplantation with melphalan-total body irradiation from HLAidentical<br />
siblings for AML in first remission: higher relapse rates with marrowderived<br />
stem cell grafts compared to blood despite similar chronic graft-versushost<br />
disease. 28 th EBMT Annual Meeting, Montreux, Switzerland. 27 th March<br />
2002.<br />
39. Administration of weekly cyclophosphamide as part of infusional induction<br />
chemotherapy (C-VAMP) does not affect subsequent peripheral blood stem cell<br />
collection in patients with myeloma. 28 th EBMT Annual Meeting, Montreux,<br />
Switzerland. 26 th March 2002.<br />
40. 20-year follow-up of allogeneic bone marrow transplantation with<br />
cyclophosphamide - TBI and cyclosporine for acute myeloid leukaemia in first<br />
complete remission. 28 th EBMT Annual Meeting, Montreux, Switzerland. 26 th<br />
March 2002.<br />
41. Does the Number of Infused CD34 Cells Affect the Long-Term Outcome of<br />
Myeloma Patients Treated with High-Dose Melphalan and Auto transplantation?<br />
7 th Congress of EHA, 6-9 th June 2002, Florence, Italy.<br />
42. The Addition of Weekly Cyclosphosphamide to Infusional Induction<br />
Chemotherapy (Vincristine, Doxorubicin, and Methylprednisolone) Does Not<br />
Affect Subsequent Stem Cell Collection in Patients with Myeloma. 7 th Congress<br />
of EHA, 6-9 th June 2002, Florence, Italy.<br />
43. Bone Marrow or Peripheral Blood Stem Cell Auto transplantation for AML in<br />
First Remission? A Matched-Pair Analysis from the Royal Marsden Hospital and<br />
the European Blood and Marrow Transplant Group (EBMT). 7 th Congress of<br />
EHA, 6-9 th June 2002, Florence, Italy.<br />
44. Early high resolution CT (HRCT) scans allow for prompt diagnosis and<br />
efficacious treatment of invasive pulmonary aspergillosis (IPA) in immunocompromised<br />
patients with haematologic malignancies. 7 th Congress of EHA, 6-<br />
9 th June 2002, Florence, Italy.<br />
45. Implications of impaired renal function at the time of initiation of infusional<br />
chemotherapy (C-VAMP) in patients with newly-diagnosed myeloma. 7 th<br />
Congress of EHA, 6-9 th June 2002, Florence, Italy.<br />
46. Clinical implications and consequences of leukapheresis to reduce tumour burden<br />
in newly-diagnosed patients with hyperleukocytosis (HL) and acute myeloid<br />
leukaemia. Annual meeting of British Society of Haematology, Brighton, 2002,<br />
47. Outcome of auto transplantation in 118 adult acute myeloid leukaemia patients in<br />
first complete remission: impact of consolidation chemotherapy (CC). Annual<br />
meeting of British Society of Haematology, Brighton, 2002,<br />
16
Dr Bhawna Sirohi’s CV<br />
48. Implication of impaired renal function at the time of initiation of infusional<br />
chemotherapy including cyclophosphamide (C-VAMP) in patients with newly<br />
diagnosed myeloma. Annual meeting of British Society of Haematology,<br />
Brighton, 2002,<br />
49. Relapse following complete remission outcome predictors in patients with<br />
secretory myeloma. ). Annual meeting of British Society of Haematology,<br />
Brighton, 2002,<br />
50. Administration of weekly cyclophosphamide as part of infusional induction<br />
chemotherapy (C-VAMP) does not affect subsequent peripheral blood stem cell<br />
collection in patients with myeloma. ). Annual meeting of British Society of<br />
Haematology, Brighton, 2002,<br />
51. 200 mg/m2 Melphalan (HDM200) and Salvage Auto transplantation in Myeloma<br />
Patients Relapsing after a Preceding Autograft. Annual meeting of American<br />
society of Haematologists, Philadelphia, 9th December 2002.<br />
52. Adult Patients with De Novo Acute Myeloid Leukaemia Receiving High-Dose<br />
Cytarabine-Based Induction Chemotherapy: A Single Centre Study of 136<br />
Patients. Annual meeting of American society of Haematologists, 2003<br />
53. 10-Year Survival in Myeloma: Have the Results Improved in the Last Decade?<br />
Annual meeting of American society of Haematologists, 2003<br />
54. Significance of Length of First Complete Remission (CR) in Newly-Diagnosed<br />
Secretory Patients with Myeloma: A Study of 131 with a Minimum Follow-Up of<br />
5 Years. Annual meeting of American society of Haematologists, 2003<br />
55. Primary Refractory (PRef) Myeloma: Recommendations for Treatment. Annual<br />
meeting of American society of Haematologists, 2003<br />
56. Prognostic Significance of Immunoparesis (Ip) at Diagnosis and Continued<br />
Complete Remission (CR) in Newly Diagnosed Secretory Myeloma Patients.<br />
Session Type: Annual meeting of American society of Haematologists, 2003<br />
57. Effect of Human Growth Hormone in Haemato-Oncology Patients Receiving<br />
Intensive Chemotherapy. A Double Blind Randomized, Placebo-Controlled<br />
Study. Annual meeting of American society of Haematologists, 2003<br />
58. 200 mg/m2 Melphalan and Autograft Followed by Maintenance Chemotherapy<br />
with 6-Mercaptopurine (6MP), Methotrexate (MTX), and Vincristine-Prednisone<br />
(VP) in 65 First Remission Acute Lymphoblastic Leukaemia Patients. Annual<br />
meeting of American society of Haematologists, 2003<br />
59. 2 posters at EBMT 2004<br />
60. Early response to platinum-based chemotherapy in non small cell lung cancer<br />
(NSCLC) predicts survival , ASCO 2005<br />
61. Use of Gemcitabine, Cisplatin and Methylprednisolone (GEM-P) with or without<br />
Rituximab in Relapsed and Refractory Patients with Diffuse Large B Cell<br />
Lymphoma, ASH 2005.<br />
62. Retrospective study of Gemcitabine, Cisplatin and Methylprednisolone (GEM-P)<br />
with or without Rituximab in Relapsed and Refractory Patients with Diffuse Large<br />
B Cell Lymphoma (DLBCL). EBMT 2006<br />
63. Long-term outcome of high-dose chemotherapy and autologous stem cell<br />
transplantation in relapsed/refractory Hodgkin's disease: A cohort of 199 pts from<br />
Royal Marsden Hospital, ASCO 2006<br />
64. The prognostic role of WHO classification, urinary 5-hydroxyindoleacetic acid<br />
and liver function tests in metastatic neuroendocrine carcinomas of the<br />
gastroenteropancreatic tract, ASCO 2006<br />
17
Dr Bhawna Sirohi’s CV<br />
65. The role of maintenance chemotherapy after auto transplantation for acute<br />
lymphoblastic leukaemia in first remission: single-centre experience of 100<br />
patients. ASH 2007<br />
66. Use of platinum-based chemotherapy in patients with triple negative breast<br />
cancer, ASCO 2008<br />
67. Trans-Atlantic Consensus on the Medical Management of Radiation Accident<br />
Victims, ASH 2008<br />
RESEARCH:<br />
I have had the opportunity to be a chief investigator and principal investigator for<br />
various clinical trials. I have also helped design and set up clinical trials from<br />
initiation to recruitment.<br />
Chief Investigator<br />
Phase-3 multi-centre, international, randomised trial evaluating Bevacizumab as<br />
adjuvant therapy following resection of cutaneous melanoma (submitted for ASCO<br />
2009).<br />
Principal investigator<br />
Study A6181170: Phase 3 randomised trial comparing Sunitinib versus Sorafenib in<br />
patients with advanced hepatocellular carcinoma trial<br />
A phase II study of PTK787 in metastatic melanoma patients<br />
A randomised double-blind Phase III trial comparing addition of STA-4783 to<br />
Paclitaxel in patients with metastatic melanoma.<br />
An Open-Label, Pharmacokinetic Study of the Safety and Tolerability of Pazopanib<br />
in Combination with FOLFOX 6 or CapeOx in Subjects with Colorectal <strong>Cancer</strong><br />
Trials at Artemis:<br />
A Randomized, Double-Blind, Placebo-Controlled, Multi-Centre Phase 3 Study of<br />
Denosumab as Adjuvant Treatment for Women with Early-Stage Breast <strong>Cancer</strong> at<br />
High Risk of Recurrence (D-CARE)<br />
Phase II Study Of Weekly Cisplatin & Paclitaxel Plus Cetuximab As Induction<br />
Therapy In Patients With Advanced Squamous Cell Carcinoma Of The Head And<br />
Neck (SCCHN).<br />
An open-label randomized comparative multicentre study to assess safety and<br />
efficacy of BIOMAb-EGFR TM (Nimotuzumab) in combination with chemotherapy<br />
versus chemotherapy alone in the treatment of patients with stage IIIb / IV non small<br />
cell lung cancer (NSCLC).<br />
Retrospective review of data for breast cancer patients<br />
Myeloma Trials<br />
1871 A phase II trial comparing the quality of life, tolerability and toxicity of PEG<br />
Intron with INTRON A in patients with myeloma.<br />
18
Dr Bhawna Sirohi’s CV<br />
2048 A randomised comparison of the effect of maintaining haemoglobin levels<br />
with weekly Eprex or with conventional anaemia management in subjects with<br />
multiple myeloma undergoing chemotherapy<br />
2122 A pilot study of Zometa in patients with multiple myeloma and stable partial<br />
remission/early relapse following complete remission.<br />
2123 Light Chain Assay in Multiple Myeloma patients in CR<br />
2127 An international, non-comparative, open-label studies of PS-341 versus high<br />
dose dexamethasone in patients with relapsed or refractory multiple myeloma.<br />
2126 An international, non-comparative, open-label study of PS-341 administered to<br />
patients with myeloma who experienced relapsed or progressive disease after having<br />
received at least four previous treatment regimes or experienced progressive disease<br />
after receiving dexamethasone in Millennium protocol M34101-039<br />
1899 A phase I open-study of the safety, tolerance, pharmacokinetics, antigenicity<br />
and efficacy of a single intravenous dose of AHM followed by multiple doses of<br />
intravenous AHM in subjects with multiple Myeloma.<br />
Infection Trials<br />
1930 An open-label, non-comparative study of FK463 for the treatment of Invasive<br />
Candidiasis<br />
1931 An open-label, non-comparative study of FK463 for the treatment of invasive<br />
aspergillosis<br />
2082 An open-label non-comparative study of the safety and efficacy of intravenous<br />
anidulafungin plus ambisome as a treatment for invasive aspergillosis<br />
2218: Caspofungin as antifungal prophylaxis in patients receiving all-SCT.<br />
1450 A prospectively randomised, double blind comparative multi-centre study to<br />
evaluate efficacy and safety of Nyotran and Amphotericin B for empirical<br />
antifungal treatment in neutropenic patients<br />
1874 A phase II study to determine the safety profile, the maximum tolerated dose<br />
and PK's of FK463 for prophylaxis of fungal infections in adult patients undergoing a<br />
bone marrow or PBSC transplant FK463 for prophylaxis<br />
Transplant Trials<br />
1812 A pilot study of upfront high-dose melphalan with autologous stem cell rescue<br />
in newly diagnosed patients with multiple myeloma.<br />
2084 Defibrotide for the treatment of hepatic veno-occlusive disease after stem cell<br />
transplantation (DF-VOD Trial)<br />
2083 Phase II study of low intensity non-myeloablative allograft following high<br />
dose Melphalan with autologous stem cell support in myeloma patients with sibling<br />
donors (UKMF).<br />
1901 A phase I pilot, open-labelled, single-centre multiple ascending dose study to<br />
evaluate the pharmacokinetics and effect on administration of STI-571 on post<br />
allogeneic stem cell transplant myeloid recovery in patients with haematological<br />
malignancies.<br />
1625 A multi-centre, open centre, non-randomised phase I-II study to investigate<br />
mobilisation by a combination of Ancestim (r-metHuSCF) and Filgrastim (rmetHuGCSF)<br />
Lenograstim versus Filgrastim<br />
Leukaemia Trails<br />
19
Dr Bhawna Sirohi’s CV<br />
2161 An open-label study to find out if ZARNESTRA/R115777 treatment is<br />
effective and safe in the treatment of patients with High Risk Myelodysplastic<br />
Syndrome (MDS).<br />
2128 A randomised trial of human growth Hormone (hGH) versus placebo in<br />
haemato-oncology patients treated intensively for prevention of loss of muscle mass<br />
and weight<br />
MRS Spectroscopy in new patients with leukaemia<br />
1395 A multiple ascending dose study evaluating the safety and efficacy of<br />
intravenous infusion of LF 08-299 administered as first line treatment in combination<br />
with corticosteroids in patients with acute GVHD. Fournier.<br />
Urology Trials<br />
PSMA DNA vaccine in prostate cancer: COREC submission and sponsorship issues<br />
AMG 114 trial - Treatment of Anaemia in Subjects with Non-myeloid Malignancies:<br />
Local R & D submission<br />
Lymphoma /GI<br />
1246: A retrospective and prospective assessment of toxicity and outcome of high<br />
dose consolidation chemotherapy in high grade Non-Hodgkin’s lymphoma and<br />
Hodgkin’s disease.<br />
2656 A retrospective review of Gemcitabine, Methylprednisolone Cisplatin (GEM-P)<br />
with or without Rituximab in patients with relapsed/refractory diffuse large B-cell<br />
lymphoma (DLBCL).<br />
2655 A retrospective study of toxicity and outcome of high dose chemotherapy with<br />
autologous stem cell transplant in patients with Hodgkin Lymphoma (HL).<br />
2657 A retrospective study of toxicity and outcome of high dose chemotherapy with<br />
autologous stem cell transplant in patients with Non-Hodgkin Lymphoma (NHL).<br />
LIFE: Phase III randomsied trial - First-line 5-Fluorouracil Regimens With or<br />
Without Oxaliplatin in Advanced Colorectal <strong>Cancer</strong><br />
Ovarian cancer<br />
Impact of second line chemotherapy with a platinum or non-platinum regimen in<br />
partially platinum-sensitive and platinum sensitive recurrent epithelial ovarian,<br />
fallopian tube and primary peritoneal cancer<br />
Breast <strong>Cancer</strong><br />
ATHENA: International multi-centre trial with the use of bevacizumab and<br />
chemotherapy in patients with newly diagnosed metastatic breast cancer. : COREC<br />
submission and participation in MREC approval process along with presentation to<br />
the Cambridge REC on behalf of the chief investigator Prof Ian Smith.<br />
INVITED LECTURES /SESSIONS<br />
1. Spectrum of fungal infections: Marsden experience. EORTC meeting, Nijmegen,<br />
Netherlands 14 th October 1998 ,<br />
2. Bone Marrow Transplantation -International Youth Science Forum, Bud<br />
Flanagan. 3 rd August 1999.<br />
3. “Towards curing Myeloma”; Tata Memorial Hospital, Mumbai 7 th October 1999<br />
4. Myeloma and renal failure –therapeutic implications, SMS Medical College,<br />
Jaipur ; 11 th October 1999<br />
20
Dr Bhawna Sirohi’s CV<br />
5. Principles of stem cell transplantation- Indraprastha Apollo Hospital, New Delhi,<br />
14 th October 1999<br />
6. State of art therapy in multiple myeloma – <strong>India</strong>n Medical Association, Meerut ,<br />
15 th October 1999<br />
7. BMT in Myeloma, Regional Study Day in Haematology on Bone Marrow<br />
Transplantation, London, 25 th November 1999.<br />
8. Use of diflucan in Haematological Malignancies, Pfizer global perception<br />
meeting, Paris, March 2000<br />
9. Fungal infections in patients with haematological malignancies: RMH experience,<br />
National Haematology meeting, Thessaloniki, Greece, 17 th November 2000.<br />
10. Stem cell transplantation in myeloma , Armed Forces Medical college, Pune,<br />
December 2000<br />
11. High-dose treatment in Acute Lymphoblastic Leukaemia, 4 th UAE International<br />
cancer congress, Abu Dhabi, 30 th January 2001<br />
12. Current Management of Myeloma, 4 th UAE International cancer congress, Abu<br />
Dhabi, 30 th January 2001<br />
13. Allogeneic peripheral blood stem cell transplantation, 4 th UAE International<br />
cancer congress, Abu Dhabi, 31 st January 2001<br />
14. Allogeneic stem cell transplantation : marrow versus peripheral blood stem cells ,<br />
Acute Leukaemia Working Party meeting, Sestri Levante, Genoa, 24 th February,<br />
2001<br />
15. International Myeloma Grand round: Case History presentation, Royal Marsden<br />
Hospital, London, 14 June 2001.<br />
16. Autologous Transplantation in Myeloma: Marsden experience, Xth Annual course<br />
in Haematology, London, 8 th November, 2001<br />
17. <strong>Cancer</strong> awareness-global scenario. <strong>India</strong>n cooperative Oncology Network, Port<br />
Blair, <strong>India</strong>, 12 th January 2002.<br />
18. Erythropoietin and anaemia: <strong>India</strong>n cooperative Oncology Network, Port Blair,<br />
<strong>India</strong>, 13 th January 2002.<br />
19. Emerging concepts in Myeloma therapy – APICON, Chennai, <strong>India</strong>, 16 th January<br />
2002<br />
20. 15 th February 2002 Myeloma and high dose chemotherapy Cripps lecture room<br />
RMH<br />
21. Fungal infections in patients with haematological malignancies , Pharmacy<br />
Summit, New Orleans , 13 April 2002<br />
22. Review of Amphocil tolerability audit, Pharmacy Summit, New Orleans , 13 April<br />
2002<br />
23. Multiple Myeloma-renal outcomes , South West Thames Renal and Transplant<br />
Unit, St Helier’s Hospital, 8 th March 2002<br />
24. Allogeneic stem cell transplantation- current scenario; National CME on<br />
Haematopoietic Stem cell Transplantation- 2002, New Delhi, 31 st March 2002<br />
25. Auto transplantation in myeloma: single centre experience: International<br />
Myeloma foundation think-tank meeting, US Virgin Islands, St Johns Retreat, 11-<br />
15 May 2002.<br />
26. High-dose treatment in myeloma- is better? ; South Thames Haematology<br />
Specialist committee, BMA House, 17 July 2002<br />
27. Growth hormone: Marsden randomised study , Munich, Sept 2002<br />
28. Current place of auto grafting in acute leukaemia ; Regional Study Day for<br />
Haematologists , 28 November 2002<br />
21
Dr Bhawna Sirohi’s CV<br />
29. Myeloma Update ; Regional Study Day for Haematologists , London, 28<br />
November 2002<br />
30. Renal disease in Myeloma, Thames Myeloma Audit, Middlesex, 20 th March 2003<br />
31. Auto transplantation in Myeloma: Issues? Golden Jubilee of International CME<br />
on Transplantation, New Delhi, March 30 2003.<br />
32. Newer agents in Myeloma, IMF Hope Trust and Effectiveness for Myeloma<br />
Patients, June 17, 2003<br />
33. New treatments for myeloma, PCT day, Parkside cancer Centre , 1 st Feb 2005<br />
34. Use of monoclonal antibodies in NHL, Multidisciplinary study day, St Raphael’s<br />
hospice, 1 st June 2006.<br />
35. Nuclear accidents: what have we learned? Role of EBMT. Gulhane Military<br />
Medical Academy, Ankara, Turkey, 24 th Nov 2006<br />
36. Pre-requisites for designation of hospitals to participate in management of<br />
radiation accidents , Munich 30 th Nov 2007<br />
37. Breast Unit Meeting, Royal Marsden Hospital, Platinum’s in triple negative breast<br />
cancer, 23 rd November 2007<br />
38. Breast cancer and pregnancy: complex care issues. National study day for nurses,<br />
17 th September 2007.<br />
39. LEAP :RMH experience, Advisory board, London, 3 rd December 2007<br />
40. Lapatinib in metastatic breast cancer, Edinburgh, 29 th January 2008<br />
41. EBMT preparedness for radiation accidents, Tandem BMT meeting , San Diego,<br />
14 th February 2008<br />
42. Allogeneic transplantation in 48 patients who received accidental irradiation, 1 st<br />
April 2008, Florence, EBMT 2008<br />
43. Use of Tyrosine kinase inhibitors in metastatic breast cancer, 19 th <strong>India</strong>n<br />
Cooperative Oncology Network meeting, 21 st September 2008, <strong>India</strong><br />
44. Global (US/European) consensus on management of radiation accident victims,<br />
Cologne, Germany , 25 th September 2008<br />
45. Targeted therapy, West Anglia nurses study day. September 30, 2008.<br />
Addenbrookes hospital, Cambridge.<br />
46. Breast and cervical cancer awareness: Public health awareness event at<br />
Swaminarayan temple, Neasden, London 11th October 2008<br />
47. Anglia Network Tyverb launch meeting: Lapatinib in principle and practice:<br />
Insights from clinical experience – what does the evidence tell us? 21 st October<br />
2008, Bedford<br />
48. Oncologic emergencies : Cambridge medical seminars, Churchill College,<br />
Cambridge, 22 nd November 2008<br />
49. Gene expression profiling in breast cancer. ISMPO annual meeting, Srinagar, 24 th<br />
October 2009<br />
50. ISMPO annual meeting, Srinagar, 24 th October 2009<br />
51. Handling of cytotoxic drugs and devices and Cross infection control. Nurses<br />
training workshop, New Delhi. 3 rd and 4 th November 2009<br />
52. Art of Caring. Max <strong>Cancer</strong> Centre, New Delhi, 8 th December 2009.<br />
53. Haematological and Oncologic emergencies, Asia Pacific Critical Care Meeting,<br />
New Delhi, 6 th December 2009<br />
54. Mechanisms of Her 2 resistance. OASIS meeting, New Delhi and Bangalore 28 th<br />
and 29 th Oct 2009<br />
55. Importance of Living will- dying with dignity. Cansupprt/IRCH Foundation<br />
course. 20 th January 2010<br />
22
Dr Bhawna Sirohi’s CV<br />
56. Role of physicians in <strong>Cancer</strong> diagnosis and staging. PROMOTE <strong>India</strong>,<br />
Hyderabad, 23 rd January 2010.<br />
57. <strong>Cancer</strong> of oesophagus. Max <strong>Cancer</strong> Centre GI forum. Noida. 2 nd February 2010<br />
58. Hyperleukocytosis in leukaemia patients. Mortality Meet, Max Healthcare. 12 th<br />
January 2010<br />
59. Targeted therapy in MBC: hits and misses, Bangalore. 5 th Feb 2010<br />
60. Gene Expression Signatures of PI3K Signaling Are Associated with Low ER<br />
Levels and the Luminal B Subtype in Breast <strong>Cancer</strong> Cell Lines and Human<br />
Tumours, and in Patients Predicts Poor Outcome (Creighton CJ et al ). San<br />
Antonio 2009 revisited, Mumbai, 14th Feb 2010<br />
61. Phase III Trial Comparing ACT with ACTH with TCH in Her2neu Positive<br />
Early Breast <strong>Cancer</strong> Patients: BCIRG 006 Study (Slamon D et al) San Antonio<br />
2009 revisited, Mumbai, 14th Feb 2010.<br />
62. Breast <strong>Cancer</strong>. ICON Meeting Kolkata. 20 th Feb 2010<br />
63. Professional conduct, Etiquette and Ethics- MCI. Max Healthcare, New Delhi, 22<br />
Feb 2010<br />
64. <strong>Cancer</strong> awareness. International Women’s day, Chitranjan Park, New Delhi, 8 th<br />
March 2010<br />
65. End of Life Care for patients with advanced cancer. Mortality Meeting. Max<br />
Healthcare, New Delhi, 9 th March 2010.<br />
66. METREPOL use in radiation accidents. Department of Health Meeting, London,<br />
12 th March 2010<br />
67. <strong>Cancer</strong> awareness, Roorkee. 14 th March 2010<br />
68. UK planning in case of a radiation accident. EBMT Education session. Vienna.<br />
23 rd March 2010<br />
69. Care of venous access devices. CVAD refresher course. New Delhi. 17 th April<br />
2010<br />
70. Case based discussion. Onco-Cardiology CME. New Delhi, 24 th April 2010<br />
71. Hyperleukocytosis and Hyperviscosity. Haemato-Oncology CME, Max <strong>Cancer</strong><br />
Centre, New Delhi, 15 th May 2010.<br />
72. Lymphadenopathy- approach to diagnosis. PROMOTE CME. Meerut, 23 rd May<br />
2010<br />
73. Tobacco and <strong>Cancer</strong>s. Tobacco Cessation Workshop. New Delhi. 3 rd June 2010.<br />
74. Chemotherapy trials- first line and beyond in advanced ovarian cancer. Best of<br />
ASCO, Hyderabad, 10 th July 2010<br />
75. Re-biopsy at the time of relapse in patients with advanced breast cancer? Best of<br />
ASCO, Hyderabad, 10 th July 2010<br />
76. <strong>Cancer</strong> management in the 21 st century. Artemis <strong>Cancer</strong> Centre. Gurgaon. 21 st<br />
August 2010<br />
77. <strong>Cancer</strong> awareness. JCI Karnal. 12 th September 2010<br />
78. Bone pain and <strong>Cancer</strong>. PromOTE Pain-ONCO CAP CME, New Delhi, 26th<br />
September, 2010.<br />
79. Phase II/III clinical trials in breast <strong>Cancer</strong>. 23 rd ICON. Allahabad. 25th September<br />
2010<br />
80. Phase II/III clinical trials in Myeloma. 23 rd ICON. Allahabad, 25 th Sept 2010.<br />
81. Adjuvant chemotherapy: role of taxanes. TMH-WCI conference, Mumbai 23 Oct<br />
2010<br />
82. Session Moderator on Haematological Malignancies, <strong>India</strong>n Society of Medical<br />
and Paediatric Oncology meeting, Bhubaneswar, 12 th Feb 2011<br />
23
Dr Bhawna Sirohi’s CV<br />
83. Albumin-bound Paclitaxel in breast cancer: <strong>India</strong>n Society of Medical and<br />
Paediatric Oncology meeting, Bhubaneswar, 12 th Feb 2011<br />
84. Cobalt nuclear accident in Delhi: Education session Nuclear accidents, Paris, 5 th<br />
April 2011<br />
85. Chairman, Session on Plasma cell dyscrasias at XIII International Myeloma<br />
workshop, Paris, 5 th May 2011<br />
86. Neoadjuvant therapy in upper GI <strong>Cancer</strong>s : breakout session at Best of ASCO,<br />
Pune 15 th July 2011<br />
87. Eribulin in Metastatic breast cancer : Best of ASCO, Pune 16 th July 2011<br />
88. Triple negative breast cancer : Panelist for the abstract discussions, Best of<br />
ASCO, Pune 16 th July 2011<br />
89. Emerging therapies in Multiple Myeloma-Carfilzomib and Pomalidomide,<br />
National Myeloma Summit, 6 th August 2011, Mumbai<br />
90. Invited faculty for the meeting Multi-sectoral Partnerships for Health Promotion<br />
and Non- Communicable Diseases (NCDs) Prevention in <strong>India</strong>, Tata Memorial<br />
Hospital, Mumbai, 5 th Aug 2011.<br />
91. Role of Physician in cancer care. IMA Gurgaon meeting, Gurgaon. 27 th August<br />
2011<br />
92. Selection of front-line chemotherapy for advanced non small cell lung cancer.<br />
New Delhi, 30 th August 2011<br />
93. Invited panellist for case based discussion. NET Expert forum. New Delhi. 3 rd<br />
Sept 2011<br />
94. Role of Physicians in diagnosis and staging of cancers. CGHS-Delhi and<br />
Gurgaon. New Delhi. 14 th September 2011.<br />
95. Oncology for non-oncologists- primary and emergency care. Artemis <strong>Cancer</strong><br />
Centre, Gurgaon. 20 th Sept 2011<br />
96. Chemotherapy update from the latest EBCTCG overview-implications for<br />
standard practice. TMC-WCI conference, Mumbai. 14 th Oct 2011.<br />
97. Venous access devices –risk management. Nursing education course. Gurgaon.<br />
20 th Oct 2011<br />
98. Molecular profiling: Heterogeneity of adenocarcinoma and targets of therapy. F-<br />
KOM, Gurgaon. 22 nd Oct 2011<br />
99. Role of Physician in cancer care. Gurgaon Nursing home and diagnostic centre<br />
association meeting, Gurgaon, 4 th Nov 2011<br />
100. CLABSI (Central line associated blood stream infections) - A Clinicians<br />
Perspective”. Hospital Infection Society – <strong>India</strong> (HISI meeting), Gurgaon, 17th<br />
December 2011.<br />
101. Lung cancer – interactive case presentation. National College of Chest<br />
Physicians (I), Monthly Clinical Meetings, <strong>India</strong> Habitat Centre, New Delhi, 18th<br />
December, 2011.<br />
102. Hodgkin Lymphoma and elderly patients- moderator for the session. European<br />
School of Oncology: Conference on Lymphoma’s and Leukaemia’s, Hotel ITC<br />
Grand Central, Mumbai, January 6, 2012.<br />
103. GIST – targeted therapy. Delhi NCR Oncology Meet, <strong>India</strong> Habitat Centre,<br />
January 11, 2012.<br />
104. Role of Physicians in <strong>Cancer</strong> Care - IMA Dwarka. January 13, 2012.<br />
105. Modern management of colorectal cancers – RGCI GI <strong>Cancer</strong>s Symposium, –<br />
17 th February 2012, New Delhi<br />
24
Dr Bhawna Sirohi’s CV<br />
106. Panel discussion on Hodgkin Lymhpoma. EBM, TMC 24 th February 2012,<br />
Mumbai<br />
107. Debate on loco-regional issues in breast cancer- moderator. Asia Breast<br />
<strong>Cancer</strong> Congress (ABCC). 4 th March 2012, Bangalore<br />
108. Hormone therapy and biomarkers in breast cancer- moderator. 26 th ICON. 24 th<br />
March 2012, Banglore<br />
109. Advanced EBMT Training Course on European Approach to the Medical<br />
Management of Mass Radiation Exposure. Multi-organ dysfunction syndrome. 4 th<br />
april 2012 , Geneva<br />
110. Best of ASCO, Jaipur, 23rd June 2012. Talks on Long term survival of<br />
EORTC study-colorectal cancer, Advances in Chemotherapy on upper GI cancers,<br />
chemotherapy standards in metastatic colorectal cancer<br />
111. ICMR Task force on cancer guidelines-chairmen’s meeting, Talk on common<br />
template for the guidelines, New Delhi, 29 th June 2012<br />
112. Recent Advances in Surgical & Medical Gastroenterology-Elsevier workshop.<br />
Targeted therapy in GI cancers, Bali, Indonesia, 21st July 2012<br />
113. 27th ICON, Moderator, Case capsule discussion on colon cancer, 15th Sept<br />
2012, Nasik<br />
114. UAE <strong>Cancer</strong> congress (Organsiisng committee, Program coordinator),<br />
Pathological CR in rectal cancers, Zoledronic acid in breast cancers, Neo-adjuvant<br />
approaches in GI cancers, 12-14th Oct 2012, Dubai<br />
115. 1st national breast cancer support group meeting, Side effects of<br />
chemotherapy in breast cancer, 6 th Oct 2012, Pune<br />
116. Asia pacific Virtual Meeting on Expert discussion on HCC management,<br />
Moderator: Case capsules of HCC, 3 rd nov 2012, Mumbai<br />
117. Colorectal <strong>Cancer</strong> Symposium 2012 , Case capsule discussion on colorectal<br />
cancers, 8th Nov 2012 , Mumbai<br />
118. ESMO guidelines group meeting, ESMO 2012 highlights for colorectal<br />
cancers, 22 nd Dec 2012, Chennai<br />
BIBLIOGRAPHY<br />
(H- Index in March 2012 for publications =20)<br />
Peer-reviewed Papers (71)<br />
1. Gera M, Gera B (Sirohi B) . Unusual second malignancies in childhood<br />
Retinoblastoma: <strong>India</strong>n Journal of Medical and Paediatric Oncology: Vol 17 No<br />
1, March 1996 (40-44).<br />
2. Vaidya S, Saika S, Sirohi B, Pai S, Advani S. Avascular necrosis of bone- a<br />
complication of aggressive therapy for acute lymphoblastic leukemia- Acta<br />
Oncologica, 1998; 37 (2): 175-7.<br />
3. S. Advani, S. Pai, D. Venzon, M. Adde, P. K. Kurkure, C. N. Nair, B. Sirohi, S.<br />
D. Banavali, R. Hawaldar, B. B. Kolhatkar, T. Vats, and I. Magrath Acute<br />
lymphoblastic leukaemia in <strong>India</strong>: An analysis of prognostic factors using a<br />
single treatment regimen. Ann. Onc., February 1999; 10: 167 - 176.<br />
4. Sirohi, B., Powles, R., Mehta, J., Raje, N., Kulkarni, S., Ramiah, V., Saso, R.,<br />
Horton, C., Bhagwati, N., Singhal, S., Treleaven, J. Complete remission rate<br />
and outcome after intensive treatment of 177 patients under 75 years of age with<br />
IgG myeloma defining a circumscribed disease entity with a new staging<br />
system. British Journal of Haematology 1999; 107: 656-666<br />
25
Dr Bhawna Sirohi’s CV<br />
5. Sirohi, B., Powles, R., Treleaven, J., Mainwaring, P., Kulkarni, S., Pandha, H.,<br />
Bhagwati, N., Horton, C., Singhal, S., Mehta, J. The role of autologous<br />
transplantation in patients with multiple myeloma aged 65 years and over. Bone<br />
Marrow Transplantation 2000; 25, (5) 533-539<br />
6. Singhal, S., Powles, R., Kulkarni, S., Treleaven, J., Sirohi, B., Millar, B.,<br />
Shepherd, V., Saso, R., Rowland, A., Long, S., Cabral, S., Horton, C., Mehta, J.<br />
Comparison of marrow and blood cell yields from the same donors in a doubleblind,<br />
randomized study of allogeneic marrow versus blood stem cell<br />
transplantation. Bone Marrow Transplantation 2000 25: (5) 501-505.<br />
7. Kulkarni, S., Powles, R., Treleaven, J., Riley, U., Singhal, S., Horton, C.,<br />
Sirohi, B., Bhagwati, N., Meller, S., Saso, R., Mehta, J. Chronic GVHD is<br />
associated with long-term risk of pneumococcal infections in bone marrow<br />
transplant patients. Blood, 2000, 95:(12) p3683-86.<br />
8. Kulkarni, S., Powles, R., Treleaven, J., Singhal, S., Horton, C., Sirohi, B.,<br />
Bhagwati, N., Tait, D., Saso, R., Killick, Pinkerton, R., Atra, A., Meller, S.,<br />
Mehta, J. Melphalan/TBI is not <strong>more</strong> carcinogenic than cyclophosphamide/TBI<br />
for transplant conditioning: follow-up of 725 patients from a single centre over<br />
a period of 26 years. Bone Marrow Transplant 2000 25,(4) 365-370.<br />
9. Powles, R., Sirohi, B., Kulkarni, S., Bhagwati, N., Saso, R., Raje, J., Horton,<br />
C., Singhal, S., Mehta, J., Treleaven, J. Acute lymphoblastic leukaemia-type<br />
intensive chemotherapy to eliminate minimal residual disease after high-dose<br />
melphalan and autologous transplantation in multiple myeloma - A phase I/II<br />
feasibility and tolerance study of 17 patients. Bone Marrow Transplant 2000<br />
25: (9) 949-956.<br />
10. Powles, R., Mehta, J., Kulkarni, S., Treleaven, J., Millar, B., Shepherd, V.,<br />
Rowland, A., Sirohi, B., Tait, D., Horton, C., Long, S., Singhal, S. Allogeneic<br />
blood and marrow stem cell transplantation in haematologic malignant disease:<br />
a randomised trial. Lancet 2000, 355: 1231-1237<br />
11. Singhal, S., Powles, R., Treleaven, J., Kulkarni, S., Sirohi, B., Horton, C.,<br />
Millar, J., Shepherd, V., Tait, D., Saso, R., Rowland, A., Long, S., Mehta, J. A<br />
low CD34+ cell dose results in higher mortality and poorer survival or marrow<br />
stem cell transplantation from HLA-identical siblings: Should CD34+ cells/kg<br />
be considered the maximum threshold? Bone Marrow Transplantation, 2000<br />
Sep, 36(5) p489-96.<br />
12. Sirohi B, Powles R L, Kulkani S, Rudin C, Saso R, Rigg A, Horton C, Singhal<br />
S, Mehta J, and Treleaven J. Glomerular filtration rate prior to high dose<br />
melphalan 200 mg/m 2 as a surrogate marker or outcome in patients with<br />
myeloma. British Journal of <strong>Cancer</strong> 2001; 85 (3):325-332.<br />
13. Sirohi, B., and Powles, R., : High-Dose Therapy in Patients with Multiple<br />
Myeloma: Oncology Spectrums,2002;2 (2): Pages 86-95.<br />
14. Sirohi B, Powles R, Kulkarni S, Rudin C, Saso R, Lal R, Singhal S, Mehta J,<br />
Horton C, Treleaven J. Comparison of new patients with Bence-Jones, IgG and<br />
IgA myeloma receiving sequential therapy: the need to regard these<br />
immunologic subtypes as separate disease entities with specific prognostic<br />
criteria. Bone Marrow Transplantation, 2001; 28:29-37.<br />
15. Sirohi B, Kulkarni S, Powles R. Some early phase II trials in previously<br />
untreated multiple myeloma: The Royal Marsden Experience. Seminars in<br />
Hematology. Vol. 38. July 2001, page 209-18.<br />
26
Dr Bhawna Sirohi’s CV<br />
16. Sirohi B and Powles R. International Myeloma Grand Round. The Lancet<br />
Oncology, Vol 2 (9) 2001: 571-579.<br />
17. Sirohi B, Powles R, Mehta J, Treleaven J, Raje N, Kulkarni S, Rudin C,<br />
Bhagwati N, Horton C, Saso R, Singhal S, Parikh P. The Implication of<br />
compromised renal function at presentation in myeloma. Medical Oncology:<br />
vol 18(1) 2001: 39-50<br />
18. Singhal, S., Powles, R., Henslee-Downey, P.J., Chiang, K.Y., Treleaven, J.,<br />
Godder, K., Kulkarni, S., van Rhee, S., Sirohi, B., Pinkerton, C.R., Meller, S.,<br />
Mehta, J. Allogeneic transplantation from HLA-matched sibling or partially<br />
HLA-mismatched related donors for primary refactory acute leukaemia. Bone<br />
Marrow Transplantation, 2002; 29(4): 291-295.<br />
19. Powles, R., Sirohi, B., Treleaven, J., Kulkarni, S., Tait, D., Singhal, S., Mehta,<br />
J. The role of post-transplantation maintenance chemotherapy in improving the<br />
outcome of autotransplantation in adult acute lymphoblastic leukaemia. Blood,<br />
2002, 100(5): 1641-1647.<br />
20. Powles, R., Sirohi, B. Kulkarni, S., Treleaven, J., Rudin, C., Sankpal, S.,<br />
Goyal, S., Horton, C., Millar, B., Saso, R., Singhal, S., Mehta, J. Collection of<br />
peripheral blood stem cells in newly diagnosed myeloma patients without any<br />
prior cytoreductive therapy: the first step towards an ‘operational cure’? Bone<br />
Marrow Transplantation, 2002, 30, 479-484.<br />
21. Singhal S, Powles R, Sirohi B, Treleaven J, Kulkarni S Mehta J. Response to<br />
induction chemotherapy is not essential to obtain survival benefit from highdose<br />
melphalan and autotransplantation in myeloma. Bone Marrow<br />
Transplantation 2002; 30 (10): 673-9.<br />
22. Mehta, J., Powles, R., Sirohi, B., Treleaven, J., Kulkarni, S., Saso, R., Tait, D.,<br />
Singhal, S. Does donor-recipient ABO-incompatible protect against relapse<br />
after allogeneic bone marrow transplantation in first remission acute myeloid<br />
leukaemia? Bone Marrow Transplantation 2002; 29 (10): 853-9.<br />
23. Elnenaei MO, Gruszka-Westwood AM, A’Hernt R, Matutes E, Sirohi B,<br />
Powles R, Catovsky D. Gene abnormalities in multiple myeloma; the<br />
relevances of TP53, MDM2, and CDKN2A. Haematologica 2003;88: 529-537.<br />
24. Kulkarni S, Powles R, Sirohi B, Treleaven J, Saso R, Horton C, Atra A, Ortin<br />
M, Rudin C, Goyal S, Sankpal S, Meller S, Pinkerton CR, Mehta J, Singhal S.<br />
Thalidomide after allogeneic haematopoietic stem cell transplantation : activity<br />
in chronic but not in acute graft-versus-host disease. Bone Marrow<br />
Transplantation 2003;32:165-70.<br />
25. Mehta J, Powles R, Sirohi B, Treleaven J, Swansbury GJ, Kulkarni S, Saso R,<br />
Singhal S. Impact of cytogenetics on the outcome of autotransplantation for<br />
acute myeloid leukaemia in first remission: is the benefit of intensive<br />
pretransplant therapy limited to patients with good karyotypes? Bone Marrow<br />
Transplantation 2003;32:157-64.<br />
26. Singhal S, Henslee-Downey PJ, Polwes R, Chiang KY, godder K, Treleaven J,<br />
Kulkarni S, Van Rhee F, Sirohi B, Pinkerton CR, Meller S, Jovanovic B, Mehta<br />
J. Haploidentical vs autologous haematopoietic stem cell transplantation in<br />
patients with acute leukaemia beyond first remission. Bone Marrow<br />
Transplantation 2003;31:889-95.<br />
27. Sirohi B, Powles R, Treleaven J, Rudin C, Kulkarni S, Frassoni F, Bacigalupo<br />
A, Singhal S, Labopin M, Michallet M, Blaise D, Reiffers J, Meloni G, Rio B,<br />
Horton C, Mehta J. Reassessing autotransplantation for acute myeloid<br />
27
Dr Bhawna Sirohi’s CV<br />
leukaemiain first remission- a matched pair analysis of autologous marrow<br />
versus peripheral blood stem cells. Accepted for publication in Bone Marrow<br />
Transplantation. 2003.<br />
28. Brian GM Durie 1 , Robert A Kyle 2 ,Andrew Belch 3 , William Bensinger 4 , Joan<br />
Blade 5 , Mario Boccadoro 6 , J Anthony Child 7 , Raymond Comenzo 8 , Ben<br />
Djulbegovic 1 , Dorotea Fantl 9 , Gosta Gahrton 10 , Jean Luc Harousseau 11 , Vania<br />
Hungria 12 , Douglas Joshua 13 , Heinz Ludwig 14 , Jayesh Mehta 15 , Angelina<br />
Rodrique Morales 16 , Gareth Morgan 16 , Amara Nouel 17 , Martin Oken 18 ,<br />
Raymond Powles 19 , David Roodman 20 Jesus San Miguel 21 , Kazuyuki<br />
Shimizu 22 , Seema Singhal 15 , Bhawna Sirohi 19 , Peter Sonneveld 23 , Guido<br />
Tricot 24 and Brian Van Ness 25. Myeloma management guidelines: a consensus<br />
report from the Scientific Advisors of the International Myeloma Foundation 1 .<br />
The Hematology Journal (2003) 4, 379-398.<br />
29. The International Myeloma Working Group. Criteria for the classification of<br />
monoclonal gammopathies, multiple myeloma and related disorders: a report of<br />
the International Myeloma working Group. British Journal of Haematology<br />
2003, 121:749-757.<br />
30. Bronwen E Shaw, Peggs K, Bird J, Cavenagh J, Hunter A, Madrigal JA, Russell<br />
N, Sirohi B, Towlson K, Williams C, Marks D. The outcome of unrelated donor<br />
stem cell transplantation for patients with multiple myeloma. British journal of<br />
Haematology 2003,123:886-895.<br />
31. Pearson IC, Sirohi B, Powles R, Treleaven J, Mortimer PS. The prevalence and<br />
nature of skin problems in a modern intensive Haemato-Oncology Unit,<br />
Hematology. 2004 Oct-Dec;9(5-6):415-23.<br />
32. B Sirohi, Powles R. Multiple Myeloma . Lancet 2004 363: 875-87.<br />
33. Durie BG, Kyle RA, Belch A, Bensinger W, Blade J, Boccadoro M, Child JA,<br />
Comenzo R, Djulbegovic B, Fantl D, Gahrton G, Harousseau JL, Hungria V,<br />
Joshua D, Ludwig H, Mehta J, Morales AR, Morgan G, Nouel A, Oken M,<br />
Powles R, Roodman D, Miguel JS, Shimizu K, Singhal S, Sirohi B, Sonneveld<br />
P, Tricot G, Ness BV. Myeloma management guidelines: a consensus report<br />
from the Scientific Advisors of the International Myeloma Foundation. J<br />
Haematol 2004, 5(3): 285-295.<br />
34. Sirohi B, Powles R, Kulkarni S, Rudin C, Frassoni F, Bacigalupo A, Singhal S,<br />
Vaidya S, Labopin M, Michallet M, Blaise D, Reiffers J, Meloni G, Rio B,<br />
Treleaven J, Horton C, Mehta J. Reassessing autotransplantation for acute<br />
myeloid leukaemia in first remission - a matched pair analysis of autologous<br />
marrow vs peripheral blood stem cells. Bone Marrow Transplant 2004, 33 (12):<br />
1209-14.<br />
35. Mehta J, Powles R, Sirohi B, Treleaven J, Kulkarni S, Singhal S. High-dose<br />
melphalan and autotransplantation followed by post transplant maintenance<br />
chemotherapy for acute lymphoblastic leukaemia in first remission. Bone<br />
Marrow Transplant 2004, 33:1107-14.<br />
36. Sirohi B., Powles R., Mehta J., Rudin C, Kulkarni S., Horton C., Saso R,<br />
Singhal S. Treleaven J An elective single autograft with high-dose melphalan:<br />
single-centre study of 451 patients. Bone Marrow Transplant. 2005 May 16;<br />
[Epub ahead of print]<br />
37. Gahrton G, Iacobelli S, Apperley J, Bandini G, Bjorkstrand B, Blade J, Boiron<br />
JM, Cavo M, Cornelissen J, Corradini P, Kroger N, Ljungman P, Michallet M,<br />
Russell NH, Samson D, Schattenberg A, Sirohi B, Verdonck LF, Volin L, Zander<br />
28
Dr Bhawna Sirohi’s CV<br />
A, Niederwieser D.The impact of donor gender on outcome of allogeneic<br />
hematopoietic stem cell transplantation for multiple myeloma: reduced relapse<br />
risk in female to male transplants. Bone Marrow Transplant. 2005 Mar;35(6):609-<br />
17.<br />
38. Sirohi, B., Powles R, Rudin C, Singhal, S., Kulkarni, S., Saso R, Horton, C.,<br />
Mehta, J, Treleaven J. Using the Original Infusional Induction Chemotherapy<br />
Again as Salvage Therapy in Myeloma Patients Relapsing After One Autograft.<br />
Hematology. 2005 Oct;10(5):361-4.<br />
39. CL Alvares, FE Davies, C Horton, G Patel, R Powles, B Sirohi, R Zuha, A Gatt,<br />
R Saso, JG Treleaven, CE Dearden, MN Potter, ME Ethell, GJ Morgan Long-term<br />
outcomes of previously untreated myeloma patients: responses to induction<br />
chemotherapy and high-dose melphalan incorporated within a risk stratification<br />
model can help to direct the use of novel treatments, accepted Br J Haematology,<br />
2005<br />
40. Sirohi B, Huddart R. The management of poor-prognosis, non-seminomatous<br />
germ-cell tumours. Clin Oncol (R Coll Radiol). 2005 Oct;17(7):543-52.<br />
41. Prescot AP, Dzik-Jurasz AS, Leach MO, Sirohi B, Powles R, Collins<br />
DJ.Localized COSY and DQF-COSY 1H-MRS sequences for investigating<br />
human tibial bone marrow in vivo and initial application to patients with acute<br />
leukemia. J Magn Reson Imaging. 2005 Oct;22(4):541-8.<br />
42. Vaidya SJ, Ortin M, Lopez-Duarte M, Sirohi B, Powles R, Treleaven J, Richard<br />
C. Haemopoietic progenitor cell transplantation in patients with previous history<br />
of invasive fungal infection. Leuk Lymphoma. 2005 Aug;46(8):1143-50.<br />
43. Sirohi B, Powles R, Chopra R, Russell N, Byrne JL, Prentice G, Potter M,<br />
Koblinger S. Assessment of Maximum Tolerated Dose (MTD) of FK463 in<br />
<strong>Cancer</strong> Patients Undergoing Haematopoetic Stem Cell Transplantation.- Bone<br />
Marrow Transplant. 2006 Jul;38(1):47-51. Epub 2006 May 22.<br />
44. Bird JM, Fuge R, Sirohi B, Apperley JF, Hunter A, Snowden J, Mahendra P,<br />
Milligan D, Byrne J, Littlewood T, Fegan C, McQuaker G, Pagliuca A, Johnson<br />
P, Rahemtulla A, Morris C, Marks DI; British Society of Blood and Marrow<br />
Transplantation. The clinical outcome and toxicity of high-dose chemotherapy<br />
and autologous stem cell transplantation in patients with myeloma or amyloid and<br />
severe renal impairment: a British Society of Blood and Marrow Transplantation<br />
study. Br J Haematol. 2006 Aug;134(4):385-90. Epub 2006 Jul 5<br />
45. Sirohi B, Powles R. Epidemiology and outcomes research for MGUS, myeloma<br />
and amyloidosis. Eur J <strong>Cancer</strong>. 2006 Jul;42(11):1671-83. Epub 2006 Jul 25.<br />
46. Gorin NC, Fliedner TM, Gourmelon P, Ganser A, Meineke V, Sirohi B, Powles<br />
R, Apperley J. Consensus conference on European preparedness for<br />
haematological and other medical management of mass radiation accidents. Ann<br />
Hematol. 2006 Oct;85(10):671-9. Epub 2006 Aug 1.<br />
47. Sirohi B, Powles R, Morgan G, Treleaven J, Kulkarni S, Horton C, Saso R, Rolfe<br />
D, Cook G, Shaw C, Wass J. Use of physiological doses of human growth<br />
hormone in haematological patients receiving intensive chemotherapy promotes<br />
haematopoietic recovery: a double-blind randomized, placebo-controlled study.<br />
Bone Marrow Transplant. 2007 Jan;39(2):115-20. Epub 2006 Dec 4.<br />
48. Arkenau HT, Chong G, Cunningham D, Watkins D, Agarwal R, Sirohi B,<br />
Trumper M, Norman A, Wotherspoon A, Horwich A. The role of intrathecal<br />
chemotherapy prophylaxis in patients with diffuse large B-cell lymphoma. Ann<br />
Oncol. 2007 Mar;18(3):541-5. Epub 2006 Dec 12.<br />
29
Dr Bhawna Sirohi’s CV<br />
49. Arkenau HT, Chong G, Cunningham D, Watkins D, Sirohi B, Chau I,<br />
Wotherspoon A, Norman A, Horwich A, Matutes E Gemcitabine, cisplatin and<br />
methylprednisolone for the treatment of patients with peripheral T-cell lymphoma:<br />
the Royal Marsden Hospital experience. Haematologica. 2007 Feb;92(2):271-2.<br />
50. Sirohi B, Powles, R, Oakervee H., Singhal S., Bishop L., Horton C., Kulkarni<br />
S., Barnett M., Dyer P., Rintala T., Mehta J, Cavenagh J.D. Upfront Collection of<br />
Peripheral Blood Stem Cells (PBSC) in New Patients with Myeloma Receiving<br />
Minimal or No Prior Cytoreductive Therapy: Comparison of Two Regimes from<br />
Royal Marsden Hospital and St. Bartholomew's Hospital. – Haematology 2007<br />
Apr;12(2):113-5.<br />
51. Sirohi B, Powles R, Lawrence D., Kulkarni S., Hollis H., Heming D., Sankpal<br />
S., Patel G., Singhal S., Treleaven J. Mehta J. An Open, Randomized,<br />
Controlled, Phase II, Single Centre, Two-Period Cross Over Study To Compare<br />
the Quality of Life (QoL) and Toxicity Experienced on PEG Interferon (P-IFN)<br />
with Interferon-a2b (IFN) in Patients with Multiple Myeloma (MM) Maintained<br />
on a Steady Dose of IFN- Annals of Oncology 2007 Aug;18(8):1388-94.<br />
52. Sirohi, B Cunningham D, Norman A, Last K, Chau I, Horwich A, Oates J,<br />
Chong G, Wotherspoon A. Gemcitabine, cisplatin and methylprednisolone (GEM-<br />
P) with or without Rituximab in relapsed and refractory patients with diffuse large<br />
B cell lymphoma (DLBCL).Hematology. 2007 Apr;12(2):149-53.<br />
53. Murphy F, Sirohi B, Cunningham D. Autotransplantation in Hodgkin<br />
Lymphoma. Expert Rev <strong>Cancer</strong> Therapy. 2007 Mar;7(3):297-306.<br />
54. Formica V, Wotherspoon A, Cunningham D, Norman AR, Sirohi B, Oates J,<br />
Chong G. The prognostic role of WHO classification, urinary 5-<br />
hydroxyindoleacetic acid and liver function tests in metastatic neuroendocrine<br />
carcinomas of the gastroenteropancreatic tract. Br J <strong>Cancer</strong>. 2007 Apr<br />
23;96(8):1178-82<br />
55. Sirohi B, Ashley S, Norton A, Popat S, Hughes S, Papadopoulos P, Priest<br />
K,O’Brien M Early response to platinum-based first line chemotherapy in non<br />
small cell lung cancer (NSCLC) may predict survival. Journal of Thoracic<br />
Oncology 2007 Aug;2(8):735-40.<br />
56. Sirohi, B, Powles R, Harousseau JL, Anderson KC. The evolving background for<br />
high-dose treatment for myeloma. Bone Marrow Transplant 2007;<br />
Dec;40(12):1097-100.<br />
57. Sirohi, B, Powles R. Future Challenges. Bone Marrow Transplant 2007;<br />
Dec;40(12):1057-64.<br />
58. Sirohi B, Cunningham D, Powles R, Murphy F, Arkenau T, Norman A, Oates J,<br />
Wotherspoon A, Horwich A. Long-term outcome of autologous stem cell<br />
transplantation in relapsed or refractory Hodgkin Lymphoma. Ann Oncol 2008<br />
Jul; 19(7):1312-9. Epub 2008 Mar 19<br />
59. Sirohi B, Powles R, Treleaven J, Kulkarni S, Saso R, Potter M, Ethell M, Morgan<br />
G, Singhal S, Mehta J. The role of maintenance chemotherapy after<br />
autotransplantation for acute lymphoblastic leukemia in first remission: singlecenter<br />
experience of 100 patients. Bone Marrow Transplant. 2008 Jul;42(2):105-<br />
12. Epub 2008 Apr 14.<br />
60. Fliedner TM, Powles R, Sirohi B, Niederwieser D; European Group for Blood<br />
and Marrow Transplantation (EBMT) Nuclear Accident Committee (NAC).<br />
Radiologic and nuclear events: the METREPOL severity of effect grading system.<br />
Blood. 2008 Jun 15;111(12):5757-8; author reply 5758-9.<br />
30
Dr Bhawna Sirohi’s CV<br />
61. Sirohi B, Arnedos M, Popat S, Ashley S, Nerurkar A, Walsh G, Johnston S,<br />
Smith IE. Platinum-based chemotherapy in triple-negative breast cancer. Ann<br />
Oncol. 2008 Nov;19(11):1847-52. Epub 2008 Jun 20 .<br />
62. Cunningham DC, Sirohi B, Pluzanska A, Utracka-Hutka B, Zaluski J, Glynne-<br />
Jones R, Koralewski P, Bridgewater J, Mainwaring P, Wasan H, Wang JY,<br />
Szczylik C, Clingan P, Chan RTT, Tabah-Fisch T, and Cassidy J.Two Different<br />
First-line 5-Fluorouracil Regimens With or Without Oxaliplatin in Advanced<br />
Colorectal <strong>Cancer</strong> (LIFE). Ann Oncol. 2009 Feb;20(2):244-50. Epub 2008 Oct<br />
14.<br />
63. Sirohi B, Powles R, Singhal S, Smith K, Jones RL, Saso R, Kulkarni S, Treleaven<br />
J, Swansbury GJ, Potter M, Morgan G, Mehta J et al. Outcome of high-dose<br />
cytarabine-based induction therapy followed by hematopoietic stem cell<br />
transplantation in acute myeloid leukemia. Leuk Lymphoma. 2008<br />
Dec;49(12):2284-90.<br />
64. Fliedner TM, Chao NJ, Bader JL, Boettger A, Case C Jr, Chute J, Confer DL, Ganser<br />
A, Gorin N-C, Gourmelon P, Graessle DH, Krawisz R, Meineke V, Niederwieser D,<br />
Port M, Powles R, Sirohi B, Weinstock DM, Wiley A, Coleman CN. Multi-organ<br />
Failure in Radiation Emergency Medical Preparedness: A US/European<br />
Consultation Workshop. Stem Cells e-published Jan 22, 2009. Stem Cells. 2009<br />
May;27(5):1205-11<br />
65. Sirohi, B, Powles R. Lenalidomide in Multiple Myeloma, Expert reviews<br />
anticancer therapy. Nov 2009;9(11):1159-1570.<br />
66. Basu B, Biswas S, Wrigley J, Sirohi B, Corrie P. Angiogenesis in cutaneous<br />
malignant melanoma and therapeutic strategies. Expert reviews anticancer<br />
therapy. Nov 2009;9(11):1583-1598.<br />
67. Sirohi, B et al A randomised comparative trial of infusional ECisF (epirubicin,<br />
cisplatin and infusional 5FU) vs conventional FEC (5FU, epirubicin and<br />
cyclophosphamide) as adjuvant chemotherapy in early breast cancer : The<br />
TRAFIC(TRial of Adjuvant 5FU Infusional Chemotherapy) trial. Ann Oncol.<br />
2010 Aug;21(8):1623-9. Epub 2010 Jan 21.<br />
68. Powles R, Sirohi B, Niederwieser D.The role of the European haematologist in a<br />
large irradiation emergency: the European Blood and Marrow Transplantation<br />
Society (EBMT) Nuclear Accident Committee (NAC). Health Physics 2010<br />
98(6): 810-4.<br />
69. Jackson C, Sirohi B, Cunningham D, Horwich A, Thomas K, Wotherspoon<br />
A.Lymphocyte-predominant Hodgkin lymphoma--clinical features and treatment<br />
outcomes from a 30-year experience. Ann Oncol. 2010 Oct;21(10):2061-8. Epub<br />
2010 Mar 23.<br />
70. Noble J, Sirohi B, Ashley S, Ladas G, Smith I.Sternal/para-sternal resection for<br />
parasternal local recurrence in breast cancer. Breast. 2010 Oct;19(5):350-4. Epub<br />
2010 Mar 20.<br />
71. Cook N, Basu B, Biswas S, Kareclas P, Mann C, Palmer C, Thomas A, Nicholson<br />
S, Morgan B, Lomas D, Sirohi B, Mander AP, Middleton M, Corrie PG. A phase<br />
2 study of vatalanib in metastatic melanoma patients. Eur J <strong>Cancer</strong>. 2010<br />
Oct;46(15):2671-3. Epub 2010 Aug 25.<br />
72.<br />
Chapters /Reviews (14)<br />
31
Dr Bhawna Sirohi’s CV<br />
73. Powles R, Sirohi B and Kulkarni S. Scientific evidence and expert clinical<br />
opinion for the investigations and management of hyperleukocytosis in adults.<br />
Chemotherapy book, Chapter 3, July 2002, pg 33-50.<br />
74. Powles R, Sirohi B and Kulkarni S. Scientific evidence and expert clinical<br />
opinion for the investigations and management of compressive syndromes in<br />
adults. Chemotherapy book, Chapter 4, July 2002, pg 51-54.<br />
75. Sirohi B, Treleaven J, Powles R, Role of Interferons, Book-Myeloma, Eds 1,<br />
Dunitz, Edited by Mehta J Singhal S, 2001, 383-396.<br />
76. Sirohi B, Raje N, Powles R. Autologous Haematopoietic stem cell<br />
transplantation for multiple myeloma and AL amyloidosis, Chapter in Clinical<br />
Bone Marrow and Blood Stem Cell Transplantation (3rd Edition). Edited by<br />
Kerry Atkinson. Cambridge University Press. 2003, p 287<br />
77. Sirohi B, Powles R. Leukaemia and Myeloma. Chapter 21 in cancer in Primary<br />
Care. Eds 1, Dunitz, Edited by Martin Gore & Douglas Russell (2003)<br />
78. Sirohi B, Cunningham D. Safety and efficacy of irinotecan plus high-dose<br />
folinic acid and 5-FU i/v bolus for metastatic colorectal cancer patients: a pooled<br />
analysis of two consecutive SICOG trials. Commentary Clinical colorectal<br />
<strong>Cancer</strong>. 2005.<br />
79. Sirohi B, Cunningham D. Salvage chemotherapy with irinotecan and cisplatin in<br />
patients with metastatic gastric cancer failing both 5-fluorouracil and taxanes. .<br />
Commentary Clinical colorectal <strong>Cancer</strong>. 2005.<br />
80. Sirohi B, Powles R. Multiple Myeloma : E-learning module for European Journal<br />
of <strong>Cancer</strong> Care , Jan 2008<br />
81. Leary AF, Sirohi B, Johnston SR Clinical trials update: endocrine and biological<br />
therapy combinations in the treatment of breast cancer. Breast <strong>Cancer</strong> Res. 2007<br />
Oct 26;9(5):112<br />
82. Sirohi, B, Smith K. Bevacizumab in the treatment of breast cancer. Expert Rev<br />
Anticancer Ther. 2008 Oct;8(10):1559-68.<br />
83. Sirohi B, Leary A, Johnston S. Ipsilateral Breast tumour recurrence: current<br />
practice and recommendations. Breast J. 2009 May-Jun;15(3):268-78.<br />
84. Basu B, Sirohi B, Corrie P.Systemic therapy for neuroendocrine tumours of<br />
gastroenteropancreatic origin. Endocr Relat <strong>Cancer</strong>. 2010 Jan 29;17(1):R75-90<br />
85. Sirohi B. <strong>Cancer</strong> management in the twenty-first century in <strong>India</strong>. <strong>India</strong>n J Med<br />
Paediatr Oncol. 2010 Apr;31(2):49-50<br />
86. Sirohi B. New Delhi metallo-β-lactamase 1. Lancet Infect Dis. 2010<br />
Nov;10(11):750; author reply 752-4.<br />
87. Shrikhande SV, Sirohi B, Goel M, Barreto SG. <strong>Pancreatic</strong> neuroendocrine<br />
tumors<strong>India</strong>n J Gastroenterol. 2012 Oct 3<br />
Abstracts -260 in peer reviewed journals.<br />
HOBBIES /INTERESTS<br />
Photography, Cinema, Theatre, Art exhibitions, Horse-Riding, Lawn Tennis, Chess<br />
and Reading.<br />
32