Use of GXII Platform in HT Screening for Mammalian ... - PerkinElmer
Use of GXII Platform in HT Screening for Mammalian ... - PerkinElmer
Use of GXII Platform in HT Screening for Mammalian ... - PerkinElmer
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Why Screen <strong>for</strong> Glycosylation Dur<strong>in</strong>g<br />
Early Process Development?<br />
Glycans regulate:<br />
•Biological activity<br />
•Half-life<br />
For MAbs:<br />
Fc region Oligos <strong>in</strong>teract<br />
with other immune<br />
system prote<strong>in</strong>s, mak<strong>in</strong>g<br />
them essential <strong>for</strong><br />
antibody function.<br />
© Lonza Biologics plc 2012 slide 24