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Schneider's first rank symptoms \(1\)

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Clozapine<br />

• Clozapine is a unique drug as it is the drug of<br />

choice for resistant schizophrenia<br />

• Side effect of agranulocytosis (incidence of 0.8%<br />

at 12 months, with a peak risk in the 3 rd month)<br />

• WCC monitoring mandatory: weekly for the <strong>first</strong><br />

18 weeks then Q4weeks<br />

• Sedation and antimuscarinic side effects<br />

• Less EPS

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