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Schneider's first rank symptoms \(1\)

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Non-neurological S/E (3)<br />

Adverse<br />

Reaction<br />

Frequency<br />

Comment<br />

Haemato<br />

logical<br />

Neutropenia<br />

Agranulocytosis<br />

Rare<br />

Rare<br />

But note – with clozapine :reversible<br />

Neutropenia (~2%) Can progress to<br />

agranulocytosis if drug maintained<br />

Thrombocytopenia<br />

Haemolytic<br />

anaemia<br />

V. Rare<br />

V. Rare<br />

Ophthalmic<br />

Lenticular deposits<br />

Pigmentary<br />

retinopathy<br />

Rare<br />

Reversible with early detection<br />

High dose, long-term thioridazine<br />

only

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