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Schneider's first rank symptoms \(1\)

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Oral vs Depot<br />

• Oral:<br />

•Depot:<br />

• First-pass metabolism<br />

• Variable bioavailability<br />

• Solves the problem of drug compliance<br />

• No <strong>first</strong>-pass effect<br />

• Decrease relapse rate<br />

• Once every 4 weeks (2 weeks for Risperdal Consta)

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