Septic shock â Monitoring methods, parameters, end points

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<strong>Septic</strong> Shock : Outcome . Mortality : 35 to 70 % Annane et al Lancet 2005 , 365 , 63-78 Mortality : 62 % (1990s) to 56 % in 2000 Excess mortality : 39% Annane et al AJRCCM 2003 , 168 , 165-72
Severe sepsis/septic <strong>shock</strong> Aims of treatment Correct . Macrocirculatory failure . Myocardial failure . Microcirculatory failure . Mitochondrial failure Restaure OXYGEN availability
Page 1: Septic shock Persistent arterial hy
Page 5 and 6: Compensated shock may persists when
Page 7: Initial Resuscitation MAP ≥ 65 m
Page 10 and 11: yes Maintain established goals MAP
Page 12 and 13: Clinical signs Skin (color - temper
Page 14 and 15: Initial Resuscitation MAP ≥ 65 m
Page 17: RAP (mmHg) before volume expansion
Page 21 and 22: Guide to Fluid Therapy in Septic Sh
Page 23 and 24: Am J Respir Crit Care Med 2000; 162
Page 25 and 26: Stroke volume variation as a pre di
Page 27 and 28: Global End-diastolic Volume Michard
Page 29: Cardiac Output High ? Low ? Adequat
Page 34 and 35: SCHEMA D’INSTALLATION du PiCCO CV
Page 36 and 37: Stroke Volume Variation SV max SV m
Page 38 and 39: Fluid challenge 500 ml (7 ml/kg) (e
Page 40 and 41: 32 patients randomized : dopamine (
Page 42 and 43: 65 85
Page 44 and 45: UF Increasing MAP ? 65 Creatinine 8
Page 49 and 50: Septic shock. Inotropic Therapy . D
Page 51 and 52: SvO 2 ScvO 2 AP TaO2 (IC Hb SaO2) V
Page 56 and 57:
ADDING DOBUTAMINE TO NOREPINEPHRINE
Page 59 and 60:
Macrocirculation and MOF The densit
Page 62 and 63:
Initial Resuscitation MAP ≥ 65 m
Page 64 and 65:
O 2
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Septic shock â Monitoring methods, parameters, end points

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Septic shock â Monitoring methods, parameters, end points