Septic shock â Monitoring methods, parameters, end points
Septic shock â Monitoring methods, parameters, end points
Septic shock â Monitoring methods, parameters, end points
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Rivers et al NEJM, 2001, 345, 1368-1377<br />
« Early Goal-directed Therapy »<br />
263 patients :<br />
. Severe sepsis<br />
. <strong>Septic</strong> <strong>shock</strong><br />
ECG, SpO 2 , UF<br />
Art cath , CVC<br />
Standard treatment<br />
n = 133<br />
CVP 8 -12 mmHg<br />
MAP > 65 mmHg<br />
UF > 0.5 ml/kg/h<br />
For 6 hours<br />
Protocol<br />
n = 130<br />
idem + ScvO 2 > 70%<br />
SaO 2 > 93%<br />
HT> 30 %