Impact Summer 2005 - The Jimmy Fund

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Rick Corman continues to “red flag” multiple myeloma Rick Corman’s latest gift of $250,000 has brought his philanthropy to Dana- Farber across the $1 million mark— and he says this is just the beginning. Corman supports multiple myeloma research by Kenneth Anderson, MD, Paul Richardson, MD, and their colleagues in DFCI’s Jerome Lipper Multiple Myeloma Center. Diagnosed with multiple myeloma in 2001, Corman vowed to give $250,000 annually as long as he continues his successful fight against the rare blood cancer. For four years, Corman, clad in a bright red blazer, has handdelivered his gift to Dana-Farber, displaying confidence in and admiration for the physician-scientists in the Lipper Center. “I’m in business and I’ve found that money motivates many people, but not this research team,” said Corman, owner and founder of Over four years, Rick Corman has given $1 million to DFCI to spur development of effective multiple myeloma therapies. Nicholasville, Ky.-based RJ Corman Railroad, LLC. “They are driven by something different—a passion to kill the disease before it kills us.” Corman’s philanthropy is inspired by the remarkable advances Anderson, Richardson, and fellow DFCI investigator Teru Hideshima, MD, PhD, have made against multiple myeloma. “They have changed treatment in extraordinary ways.” For its part, the Lipper Center team agrees that Corman has helped spur progress. “Rick has become both a dear friend and a patient loved by all,” said Richardson. “His courage and commitment have been simply tremendous, and his generosity of spirit is inspirational.” Anderson says, “His kindness has helped caregivers and patients alike. We are lucky to have him on our team!” Aaron Foundation gift funds groundbreaking Kinase Project Send a message of hope this holiday season Since its establishment, the Aaron Foundation has been offering financial support to organizations and programs that make a positive impact in the world of education, culture, and science. Most recently, the foundation turned this altruistic focus to Dana- Farber with a $100,000 grant directed toward the Institute’s Kinase Project. This revolutionary research initiative aims to probe the genetic mutations that lead to cancer development and identify potential drugs to target these specific anomalies. “This research has far-reaching and crossfunctional potential, as its results could lead to a better understanding of a number of cancers,” said Aaron Foundation Trustee James Rabb, MD. “With the lifesaving possibilities so great, we see it as a good place to put our support.” “The hope is that this research will lead in the direction where it can do the most good—helping people overcome their diseases,” added Rabb’s David Livingston, MD, is leading DFCI’s cousin and fellow foundation trustee, Kinase Project, a pioneering research Jane Rabb, PhD. endeavor set to change the future of Led by David Livingston, MD, deputy cancer care and research. director of the Dana-Farber/Harvard Cancer Center and the Emil Frei Professor of Genetics and Medicine at Harvard Medical School, along with DFCI colleagues Matthew Meyerson, MD, PhD, and William Sellers, MD, this groundbreaking study will specifically examine some 150 different kinases, or cell enzymes, that have been found to aid cancer development when mutated. “This generous gift from the Aaron Foundation is important in helping us move forward with this critical research. Our overarching goal is to make available to cancer patients new treatments that are safer and more effective than the ones currently available,” said Livingston. Show your commitment to fighting cancer by purchasing a box of holiday greeting cards. All proceeds will benefit Dana-Farber’s lifesaving mission. Visit www.jimmyfund.org/holiday to view a selection of festive designs and order your cards, or call Charles Savicki at (617) 632-5420. CHAMPION A WINNING CAUSE Get into the spirit of the season. Choose from these one-of-a-kind Boston Red Sox and New England Patriots collectible ornaments. All proceeds from these limited edition pieces will benefit the Jimmy Fund and Dana-Farber's lifesaving mission. To order, please visit us online at www.jimmyfund.org/holiday or call Charles Savicki at (617) 632-5420. (ornament size: approximately 2.5” x 3”) 6 Impact Summer 2005
Need the perfect gift? Visit www.dana-farber.org/celebration-tribute. Sacklers steer support for rare cancer Raymond Sackler, MD, and his wife, Beverly, are international philanthropists who have long championed the arts and sciences. One scientific area they have specifically supported has been research into carcinoid and neuroendocrine tumors, rare cancers that do not typically attract significant funding. With the help of their Chief Scientific Officer Arnold Levine, PhD, the couple have assembled the foremost talent in the field. Their interest led them to two noted Dana- Farber investigators: Matthew Meyerson, MD, PhD, and Matthew Kulke, MD. After initially supporting these scientists’ work in 2003, the Sacklers have given new gifts of $500,000 and $250,000 to Meyerson and Kulke, respectively. “Drs. Meyerson and Kulke have proposed and partially accomplished goals that will significantly contribute to the basic science and clinical understanding of carcinoid and neuroendocrine cancers,” said Evan Vosburgh, MD, executive director of the Raymond and Beverly Sackler Foundation. “We hope that their work will help educate and motivate others to pursue research in this area, and that they will be successful at obtaining continued support to expand their research.” With continued support from Raymond and Beverly Sackler, DFCI’s Matthew Kulke, MD, (left) and Matthew Meyerson, MD, PhD, (right) are uncovering the genetic causes of neuroendocrine tumors. Delving deeper The Sacklers’ backing has led Meyerson and his team to uncover the function of once-mysterious proteins that play a critical role in the development of neuroendocrine cancer. They studied tumor suppressor proteins that normally prevent neuroendocrine cancer but are inactivated in the tumors. Additionally, they found that two such proteins, menin and parafibromin, control gene activity and that this activity is deficient in the tumors. “This discovery opens new opportunities for the treatment of neuroendocrine tumors and for cancer therapies more generally,” said Meyerson. For Kulke, early support from the Sacklers helped him to build a database of neuroendocrine patients’ clinical information and blood and tumor samples. With the couple’s new gift, Kulke’s team is leveraging this repository, which now comprises more than 250 patients, to pinpoint the pathways involved in tumor development and uncover clues for treatment strategies. “Through their early support of Dana-Farber’s neuroendocrine tumor research, the Sacklers planted a seed that has rapidly grown and is already bearing fruit,” said Kulke. “We are incredibly grateful for their initial and continuing support of our efforts.” Verizon Jimmy Fund Scooper Bowl dishes up enthusiastic support Thousands of ice cream lovers flocked to the Verizon Jimmy Fund Scooper Bowl June 7, 8, and 9 on Boston’s City Hall Plaza to indulge in their favorite frozen treats and to support New England’s favorite charity. The 23rd annual outdoor festival kicked off the lazy, hazy days of summer in grand style by raising its largest amount ever—more than $190,000—for the Jimmy Fund and Dana-Farber. The all-you-can-eat event attracted people of all ages, from hungry city workers enjoying their lunchtime breaks to schoolchildren holding hands on class outings. This year, they had their pick of more than 65 flavors of ice cream, frozen yogurt, and sorbet, including “Curse Reversed,” which celebrates the world championship Boston Red Sox, “Baseball Nut,” “Fenway Fudge,” “Thunder’N’Lightning,” and the “Last Straw,” provided by 10 generous companies (see sidebar). “This is always a wonderful event, and we are grateful to the people of Boston for welcoming the Scooper Bowl year after year with such enthusiasm,” said Mike Andrews, chairman of the Jimmy Fund. “We are especially thankful to the participating companies, which contributed more than 10,000 gallons of ice cream, and to Verizon and all our sponsors for making this event a great success.” Title Sponsor: Verizon Vendors: Baskin-Robbins Ben & Jerry’s Brigham’s /Élan Cold Stone Creamery Edy’s Grand Ice Cream Garelick Farms Good Humor-Breyer’s Ice Cream Häagen-Dazs ® Blue skies and soaring temperatures made the Scooper Bowl the place to be for (left to right) Tykera and Isis Williams. Thank you to our generous supporters H.P. Hood Kemps ® In-kind Sponsors: Champion Expo Nationwide GE Capital Poland Spring Solo Cup Company Media Sponsors: Boston.com Community Newspaper Company Sunday, October 9, 2005 B.A.A. HALF MARATHON Presented by Dana-Farber Cancer Institute and the Jimmy Fund You are invited to join the Dana-Farber Runners in the race toward the ultimate finish line: a world without cancer. For more details and online registration information, log on to www.jimmyfund.org/half-marathon or call (617) 632-1970. Impact Summer 2005 7
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