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Impact Summer 2005 - The Jimmy Fund

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Volume 8 • Issue 3<br />

<strong>Impact</strong><br />

Thanking those who make a difference.<br />

<strong>Summer</strong> <strong>2005</strong><br />

www.jimmyfund.org and www.dana-farber.org<br />

Stop & Shop Triple Winner Game marks<br />

15 years of fighting pediatric cancer<br />

3<br />

Faithful<br />

Family<br />

9<br />

Spirited<br />

Sailors<br />

In <strong>2005</strong>, Stop & Shop Supermarket Company<br />

was awarded the prestigious Silver Halo Award<br />

from the Cause Marketing Forum for its<br />

continuing support of the <strong>Jimmy</strong> <strong>Fund</strong> through<br />

the Triple Winner Game. Stop & Shop President<br />

and CEO Marc Smith is pictured above.<br />

Over the years, Stop & Shop<br />

Supermarket Company has served<br />

as a steadfast ally in the <strong>Jimmy</strong><br />

<strong>Fund</strong>’s battle against pediatric brain<br />

tumors, resulting in the founding of the<br />

Stop & Shop Family Pediatric Brain Tumor Clinic at Dana-Farber in<br />

1997. <strong>The</strong> center’s establishment and subsequent growth could not have<br />

been possible without the retail grocery chain’s support through its Triple<br />

Winner Game. <strong>The</strong> popular program celebrated its 15th anniversary this<br />

year and observed the occasion by raising $4 million, bringing its overall<br />

fundraising total to a victorious $33 million.<br />

“This milestone could not have been reached without the unwavering<br />

commitment to pediatric brain cancer cures made by our customers,<br />

employees, distributors, and suppliers,” said Marc Smith, president and<br />

CEO of Stop & Shop. “<strong>The</strong>ir dedication to the Triple Winner Game<br />

program has allowed Dana-Farber to offer new treatments and make<br />

medical advances that were never dreamed possible 15 years ago.”<br />

<strong>The</strong> Triple Winner Game, which kicked off on April 17 and ran until<br />

July, allowed Stop & Shop’s valued customers throughout the Northeast<br />

to contribute $1 to benefit cancer care and research. In return, they<br />

10<br />

Committed<br />

Cyclists<br />

11<br />

Elegant<br />

Event<br />

15<br />

Lasting<br />

Legacy<br />

continued on page 8<br />

Embarking on the future: PMC riders pedal toward cures<br />

When he founded the<br />

country’s first fundraising<br />

bike-a-thon in 1980,<br />

Billy Starr was not aware of the<br />

impact it would have on the lives<br />

of those facing cancer. “Almost<br />

immediately after the first Pan-<br />

Massachusetts Challenge, I realized<br />

I had tapped into something more<br />

powerful than the money we had<br />

raised,” recalled Starr.<br />

Now in its 26th year, the Pan-<br />

Massachusetts Challenge (PMC) and<br />

its devoted riders maintain an incredible<br />

spirit of inspiration, determination,<br />

and energy as they take on the<br />

challenging course to fight cancer.<br />

In <strong>2005</strong>, Starr expects the event to<br />

raise $21 million and bring its total<br />

contribution to the <strong>Jimmy</strong> <strong>Fund</strong> to<br />

more than $143 million. <strong>The</strong> PMC<br />

has grown to be the nation’s most<br />

successful athletic fundraising event,<br />

leading the way in efficiency by giving<br />

97 percent of all money raised<br />

to support the lifesaving work of<br />

Dana-Farber.<br />

“<strong>The</strong> PMC has made what we do at<br />

Dana-Farber possible,” said Institute<br />

President Edward J. Benz Jr., MD.<br />

“When they write the history of how<br />

cancer was conquered, the PMC will be<br />

in chapter one.”<br />

Going the distance<br />

On Aug. 6 and 7, more than 4,000<br />

cyclists hailing from 35 states and six<br />

countries rode across the commonwealth.<br />

Cancer survivors, current<br />

patients, and supporters pedaled<br />

one of six taxing courses between<br />

Sturbridge and Provincetown, Mass.<br />

Nearly 2,200 volunteers helped make<br />

the event a reality and were instrumental<br />

to the weekend’s success. As<br />

presenting co-sponsors, the Boston<br />

Red Sox and Overstock.com made the<br />

event possible, while 200 other generous<br />

companies provided in-kind and<br />

financial contributions.<br />

Below, left to right:<br />

<strong>The</strong> PMC draws its<br />

share of celebrities,<br />

including Team 9<br />

members and Red<br />

Sox wives Kathryn<br />

Nixon, Dawn Timlin,<br />

Nixon’s friend<br />

Bassima Connelly,<br />

and Shonda Schilling.<br />

Above: Sox President and CEO<br />

Larry Lucchino, a two-time<br />

cancer survivor treated at<br />

Dana-Farber, personally thanks<br />

the PMC riders who have<br />

helped raise a combined $143<br />

million for the Institute over<br />

the last 26 years.<br />

continued on page 10<br />

Left: Massachusetts Sen. John Kerry,<br />

a cancer survivor, shows his commitment<br />

to finding cures by joining<br />

more than 4,000 fellow cyclists.<br />

Right: A sea of riders makes a mad<br />

dash from the starting line in<br />

Sturbridge, Mass., anticipating the<br />

192-mile journey that lies ahead.


Lively summer events season scores<br />

a home run for Dana-Farber<br />

Dear Friends,<br />

<strong>The</strong> <strong>Jimmy</strong> <strong>Fund</strong><br />

is extremely thankful<br />

to boast a vibrant<br />

calendar of events<br />

that reflects the<br />

community’s<br />

extraordinary dedication<br />

to Dana-<br />

Farber’s fight against<br />

cancer. In <strong>2005</strong> alone, thousands of<br />

volunteers will rally for the cause by<br />

initiating more than 500 fun-filled<br />

fundraising events.<br />

This <strong>Impact</strong> spotlights just a few<br />

of the festivities that took place during<br />

our busiest summer season to<br />

date. In June, we launched the<br />

<strong>Jimmy</strong> <strong>Fund</strong> Regatta, which attracted<br />

hundreds of competitive sailors. <strong>The</strong><br />

inaugural event set sail in Newport,<br />

R.I., and sped past its $100,000<br />

fundraising goal. In July, Institute<br />

Trustee George Cloutier opened his<br />

Nantucket home for the second<br />

annual Boogie on Low Beach “funraiser,”<br />

which garnered more than<br />

$500,000 through ticket<br />

sales and a fabulous<br />

auction. And in August,<br />

avid baseball fans took<br />

to the field for the 14th<br />

annual John Hancock<br />

Fantasy Day at Fenway<br />

Park. Participants<br />

helped raise more than<br />

$620,000 as they lived<br />

their dreams and played ball like<br />

their favorite Boston Red Sox heroes.<br />

You’ll also read about the more<br />

than 4,000 Pan-Massachusetts<br />

Challenge (PMC) cyclists and 2,200<br />

volunteers who helped raise millions<br />

for Dana-Farber during their August<br />

odyssey across the commonwealth.<br />

Under the leadership of PMC<br />

Founder and Executive Director Billy<br />

Starr, the nation’s original fundraising<br />

bike-a-thon has raised an incredible<br />

$143 million for DFCI over its 26-<br />

year history.<br />

Finally, thousands of men and<br />

women hit the fairways for the first<br />

half of the <strong>2005</strong> <strong>Jimmy</strong> <strong>Fund</strong> Golf<br />

season. By mid-July, 78 of the 150<br />

total tournaments had already raised<br />

$2.5 million toward the program’s<br />

$5.2 million annual goal. Integral to<br />

this success were new events—such as<br />

the one sponsored by Sea View<br />

Technologies in Exter, N.H.—as well<br />

as more mature tournaments, including<br />

the 26th Annual <strong>Jimmy</strong> <strong>Fund</strong><br />

Golf Tournament/Jeffrey Vinick<br />

Memorial, which was played on five<br />

courses this year.<br />

As you can see, it has been a truly<br />

exciting summer. Thank you to each<br />

and every one of our event participants,<br />

volunteers, sponsors, and<br />

supporters who have given so generously<br />

of their time and resources.<br />

Collectively, the funds raised through<br />

these events directly support the<br />

search for cancer cures. We couldn’t<br />

do it without you!<br />

Susan S. Paresky<br />

Senior Vice President for Development<br />

Fantasy Day bats in big fundraising<br />

for the <strong>Jimmy</strong> <strong>Fund</strong><br />

<strong>The</strong> excitement surrounding the legendary 2004<br />

Boston Red Sox World Series victory was still going<br />

strong this summer as fans lined up for a chance to<br />

participate in the 14th annual John Hancock Fantasy Day at<br />

Fenway Park. At Fantasy Day, people made gifts to<br />

the <strong>Jimmy</strong> <strong>Fund</strong> for the chance to play ball like<br />

their Red Sox heroes. Held on Aug. 6, the baseball<br />

extravaganza earned more than $620,000 to<br />

help Dana-Farber strike out cancer.<br />

For many, playing in historic Fenway was a major<br />

league dream. Fans were able to hit one against the<br />

famed left-field wall, the Green Monster, or play in the outfield<br />

to snag some fly balls and a piece of baseball glory.<br />

From early in the morning until after sunset, these amateurs<br />

became pros, with memories courtesy of the generosity of<br />

presenting sponsor John Hancock Financial Services.<br />

“As a dedicated supporter of both the <strong>Jimmy</strong> <strong>Fund</strong> and<br />

Major League Baseball, we see Fantasy Day as a great opportunity<br />

for our company to demonstrate its deep commitment<br />

to improving the lives<br />

of cancer patients<br />

everywhere by participating<br />

in<br />

America’s favorite<br />

pastime,” said Robert<br />

Friedman, assistant<br />

vice president of<br />

This novice baseball player is poised to<br />

hit one against Fenway Park’s famed<br />

left-field wall, the Green Monster.<br />

sports and event<br />

marketing at<br />

John Hancock.<br />

THE<br />

T O<br />

B E<br />

N E F<br />

I T<br />

JIMMY FUND<br />

Robert Russo (left), and his father, Bob, both devout New<br />

York Yankees fans, demonstrated an even greater allegiance<br />

to the <strong>Jimmy</strong> <strong>Fund</strong> by participating in the Boston<br />

Red Sox-themed Fantasy Day event.<br />

Rivals come together for a great cause<br />

For most New York Yankees fans, the idea of playing<br />

ball at Fenway while wearing Sox uniforms would be sacrilegious.<br />

However at this year’s Fantasy Day, Robert Russo<br />

of Astoria, N.Y., and his friends and family hit the field,<br />

proving that even the greatest rivalry in sports takes a back<br />

seat when it comes to fighting cancer. Diagnosed with sarcoma<br />

in 1999, Russo came to Dana-Farber to combat this<br />

difficult-to-treat disease. With his cancer now stabilized,<br />

he saw Fantasy Day as a great way to give back to the<br />

place that continues to give him a second chance at life.<br />

“If it weren’t for Dana-Farber, I would not be here to<br />

have the opportunity to play ball at all,” said Russo.<br />

“Though it isn’t pleasant to have to wear the Red Sox<br />

jersey, it’s definitely worth it knowing that the money<br />

raised will help others.”<br />

<strong>Impact</strong><br />

<strong>Summer</strong> <strong>2005</strong> • Volume 8 • Issue 3<br />

This issue covers gifts received and finalized<br />

through the spring and summer of <strong>2005</strong>.<br />

<strong>Impact</strong>, a newsletter of Dana-Farber Cancer<br />

Institute and the <strong>Jimmy</strong> <strong>Fund</strong>, is published by the<br />

Department of Communications in collaboration<br />

with the Division of Development for friends and<br />

supporters of Dana-Farber and the <strong>Jimmy</strong> <strong>Fund</strong>.<br />

President, Dana-Farber Cancer Institute<br />

Edward J. Benz Jr., MD<br />

Chief of Staff<br />

Stephen E. Sallan, MD<br />

Chief Medical Officer<br />

Lawrence Shulman, MD<br />

Chief Scientific Officer<br />

Barrett Rollins, MD, PhD<br />

Chair of Medical Oncology<br />

James Griffin, MD<br />

Chair of Pediatric Oncology<br />

Stuart H. Orkin, MD<br />

Senior Vice President for Development<br />

Susan S. Paresky<br />

Chairman of the <strong>Jimmy</strong> <strong>Fund</strong><br />

Michael J. Andrews<br />

Senior Vice President for Communications<br />

Steven R. Singer<br />

<strong>Impact</strong> Editors<br />

Laura DeCoste, Dawn Stapleton<br />

Contributors<br />

Alan Caplan, Michael Elvin, David Ferreira,<br />

Brian Geer, Bob Israel, Sara Johnson,<br />

Kristin Lacey, Susan Rice, Beth Rossi,<br />

Lora Sharpe, Tom Ulrich, Coral Vogel<br />

Art Director<br />

John DiGianni<br />

Designer<br />

Irina Zlobina<br />

Production Coordinator<br />

Jeff Cleary<br />

Photographers<br />

Lucien Capehart, Lisa Cohen, Karen Cummings,<br />

John Deputy, Roger Farrington, Dan Furness,<br />

Steve Gilbert, Shawn Henry, Justin A. Knight,<br />

Matthew McKee, Mark Ostow, Philip Porcella,<br />

Jack Slomovitz Photographers,<br />

Coral Vogel, Laura Wulf<br />

Requests for copies of <strong>Impact</strong> may be sent to:<br />

DFCI Development Office<br />

10 Brookline Place West, 6th Floor<br />

Brookline, MA 02445-7226<br />

(617) 632-3019<br />

or download an issue at<br />

www.dana-farber.org/impact<br />

Since its founding in 1947 by the late Sidney<br />

Farber, MD, Dana-Farber Cancer Institute has<br />

been committed to a single mission: providing<br />

cancer patients with the best treatments available<br />

today, while developing the cures for tomorrow.<br />

Its researchers are also making strides against<br />

illnesses as devastating as AIDS and as ordinary<br />

as the common cold.<br />

A principal teaching affiliate of Harvard Medical<br />

School, the Institute is a founding member of<br />

the Dana-Farber/Harvard Cancer Center, one of<br />

39 comprehensive cancer centers designated by<br />

the National Cancer Institute. Dana-Farber is<br />

also one of 20 federally designated Centers for<br />

AIDS Research in the United States. In addition<br />

to providing advanced training for cancer physicians<br />

and researchers, the Institute conducts<br />

community-based programs in cancer control<br />

and detection throughout New England.<br />

Much of the work of Dana-Farber is made<br />

possible by the generous supporters of the<br />

<strong>Jimmy</strong> <strong>Fund</strong>, the fundraising organization<br />

named for one of Dr. Farber’s young patients.<br />

Founded in 1948, the <strong>Jimmy</strong> <strong>Fund</strong> is an official<br />

charity of the Boston Red Sox, the Massachusetts<br />

Chiefs of Police Association, the annual Pan-<br />

Massachusetts Challenge bike-a-thon, and the<br />

Variety Children’s Charity of New England.<br />

Each year, thousands of volunteers and donors<br />

organize and participate in <strong>Jimmy</strong> <strong>Fund</strong> events.<br />

2 <strong>Impact</strong> <strong>Summer</strong> <strong>2005</strong>


Giving is easy when you visit us online at www.dana-farber.org.<br />

Quick family honors second<br />

clinical researcher with<br />

senior investigatorship<br />

Aesclepian Society celebrates<br />

extraordinary generosity<br />

Named for Aesclepius, the<br />

Roman god of medicine, the<br />

Aesclepian Society recognizes<br />

the most loyal benefactors of<br />

Dana-Farber and the <strong>Jimmy</strong><br />

<strong>Fund</strong>. Through one-time commitments<br />

of $1 million or more,<br />

these generous donors have<br />

helped to profoundly shape<br />

the Institute’s future.<br />

Fifteen new individuals,<br />

families, and organizations were<br />

inducted into this intimate circle<br />

on May 4, joining the 75 members<br />

welcomed at the society’s<br />

inaugural gathering in 2003.<br />

Held at the Ritz-Carlton Boston,<br />

the Aesclepian Society dinner<br />

featured personal messages of<br />

thanks from Institute President<br />

Edward J. Benz Jr., MD, and<br />

Board of Trustees Chairman<br />

Gary Countryman.<br />

A 27-year cancer survivor, Institute<br />

Trustee Barbara Sadowsky<br />

shared her inspirational story<br />

and said she was living proof of<br />

the amazing care Dana-Farber<br />

provides. Keynote speaker and<br />

Harvard University President<br />

Lawrence <strong>Summer</strong>s, who is also<br />

a cancer survivor, discussed the<br />

powerful convergence of science<br />

and medicine at Harvard and<br />

throughout Boston, as well as<br />

Dana-Farber’s leadership role in<br />

this area.<br />

Above: President Benz (left)<br />

welcomed Board Chairman Gary<br />

Countryman into the Aesclepian<br />

Society and thanked him for his<br />

long-standing support.<br />

Twice, the Quick family has become intimately connected with Dana-<br />

Farber through the treatment of a loved one. And both times, they have<br />

joined together to honor the heroic care and groundbreaking research of<br />

an Institute physician.<br />

In 1999, DFCI Chief of Staff Stephen E. Sallan, MD, a renowned authority<br />

on acute lymphoblastic leukemia (ALL), was recognized with the Quick Family<br />

Senior Investigatorship in Pediatric Oncology for his successful treatment of<br />

Institute Trustee Nancy (Quick) Gibson’s son.<br />

<strong>The</strong> Quicks—mother Regina; sons Christopher, Leslie III, Peter, and Thomas;<br />

and daughters Mary Pedersen, Patricia DeVisscher, and Nancy Gibson—have<br />

now extended a similar honor to George Demetri, MD, by establishing the<br />

Quick Family Senior Investigatorship in Medical Oncology. Demetri, director of<br />

the Center for Sarcoma and Bone Oncology (CSBO), cared for late Institute<br />

Trustee and family patriarch Leslie Jr. during his battle with sarcoma. Demetri’s<br />

clinical efforts and pioneering work on novel therapeutics touched the entire<br />

family, prompting them to create the new investigatorship.<br />

“George has done and continues to do great work,” said Leslie III, “and this<br />

gift is a small acknowledgment of his success. <strong>The</strong>re are cures for all cancers out<br />

there and we, as a family, believe that Dana-Farber’s position as a leader in collaborative<br />

science will bring those cures to reality.”<br />

A paradigm for all cancers<br />

This new academic chair, endowed with a $2.5 million gift from the family,<br />

will bolster efforts by Demetri, a world expert on the biology and treatment of<br />

sarcomas, and his team in<br />

the CSBO. Together, they<br />

are working to unlock the<br />

molecular secrets of these<br />

relatively rare tumors and<br />

transform the knowledge<br />

gained into new therapeutic<br />

strategies. For example, the<br />

“<strong>The</strong>re are cures for all cancers out<br />

there and we, as a family, believe<br />

that Dana-Farber’s position as a<br />

leader in collaborative science<br />

will bring those cures to reality.”<br />

— Leslie Quick III<br />

team broke new ground with the use of “targeted” drugs like Gleevec ® and<br />

SU11248 (SUTENT) to treat the previously untreatable gastrointestinal stromal<br />

tumor (GIST).<br />

“<strong>The</strong> work of our entire team here at Dana-Farber, together with our collaborators<br />

worldwide, has made it possible for patients with GIST and other sarcomas<br />

to live longer than ever before,” Demetri said. “With the generous and<br />

visionary support of the Quick Investigatorship, we will continue to expand our<br />

work in this unique, team-focused environment.”<br />

<strong>The</strong> DFCI team’s efforts have also made sarcomas valuable models for understanding<br />

the intricacies of numerous cancers.<br />

“Sarcomas provide important clues to the causes and treatments of many cancers,<br />

from solid tumors to blood cancers,” explained Demetri. “By studying<br />

sarcomas clinically, we are gaining insights critical to cancer research in general.<br />

Simultaneously, we are developing new drugs for sarcoma patients who have a<br />

genuine unmet medical need.”<br />

Demetri continued, “I am deeply grateful to the entire Quick family for its<br />

ongoing support and for the recognition that the work here at Dana-Farber, built<br />

upon past successes, present science, and future applications, will ultimately help<br />

overcome the challenges<br />

of cancer.”<br />

<strong>The</strong> Quick family, including (above, left to right)<br />

Regina Quick, Thomas Quick, and Institute Trustee<br />

Nancy Gibson, has banded together to honor DFCI’s<br />

George Demetri, MD, (inset) with the Quick Family<br />

Senior Investigatorship in Medical Oncology.<br />

<strong>Impact</strong> <strong>Summer</strong> <strong>2005</strong> 3


Get involved, have fun, and beat cancer at www.jimmyfund.org.<br />

Golfers take a swing against cancer<br />

This summer on New England courses and beyond, golfers were teeing<br />

up for the <strong>Jimmy</strong> <strong>Fund</strong>. By mid-July, 78 of the 150 total tournaments<br />

in <strong>2005</strong> had already raised an amazing $2.5 million toward <strong>Jimmy</strong> <strong>Fund</strong><br />

Golf’s $5.2 million annual goal. Participants enjoyed time on the fairways while<br />

raising critical funds for Dana-Farber.<br />

Tournaments honored friends’, family members’, and colleagues’ battles<br />

with cancer. <strong>The</strong> Mark Ungerer Driving for the Cure Memorial Golf<br />

Tournament, for instance, paid tribute to the life of a beloved friend to many.<br />

Ungerer bravely faced cancer and was known for his generosity in donating his<br />

time to numerous community causes. Held July 10–11 at <strong>The</strong> International in<br />

Bolton, Mass., the tournament raised more than $440,000.<br />

the 26th Annual <strong>Jimmy</strong> <strong>Fund</strong> Golf<br />

Tournament/Jeffrey Vinick Memorial.<br />

This popular event celebrated its<br />

greatest success to date by raising a hefty<br />

$415,000 on June 20, bringing its cumulative<br />

fundraising tally to more than $4.5<br />

million since 1980.<br />

<strong>The</strong> tournament’s celebration dinner was<br />

held at the Basketball Hall of Fame in<br />

Springfield, Mass., and brought together<br />

golfers from each of the five different<br />

courses where the tournament was played.<br />

Among the guests was this year’s Sadowsky<br />

At the <strong>Jimmy</strong> <strong>Fund</strong> Players<br />

Tournament, co-organizer Jim<br />

Dow (left) and Jim Sims plan their<br />

strategy from the tee.<br />

Visionary Award winner, Police Chief Donald Maia of Amherst, Mass. <strong>The</strong><br />

award is named for Institute Trustees Barbara and Jim Sadowsky and given to<br />

those who make an extraordinary commitment to an event that provides<br />

annual support to the <strong>Jimmy</strong> <strong>Fund</strong> and the mission of DFCI. Chief Maia<br />

joined forces with the <strong>Jimmy</strong> <strong>Fund</strong> in 1961, serving as the creator and first<br />

president of the <strong>Jimmy</strong> <strong>Fund</strong> Council of Western Massachusetts. He inspired<br />

a legacy of grassroots fundraising.<br />

Left to right: Bob Kletjian, vice chairman at UNICCO; Stan Oldfield, retired executive<br />

from TJX; Rick Kletjian, vice chairman at UNICCO; and <strong>Jimmy</strong> <strong>Fund</strong> Chairman Mike<br />

Andrews wrap-up 18 holes at the <strong>Jimmy</strong> <strong>Fund</strong>/UNICCO Golf & Tennis Classic.<br />

“When it came time to give, Mark Ungerer would identify a gap and ask<br />

‘How can I help to fill it?’” said Jim Coghlin, co-chairman of the Ungerer<br />

Tournament. “Our golf tournament to benefit the great work at Dana-Farber is<br />

our way, as a community of friends, to honor the memory of a great man and<br />

to have a heck of a good time in the process.”<br />

Coghlin added, “Honoring those who have touched our lives brings out the<br />

best in us. Honoring those who have touched the lives of countless people in need<br />

brings out the best in a community.”<br />

Another tournament that made a great impact in the fight against cancer was<br />

<strong>The</strong> commitment of many<br />

Numerous other <strong>Jimmy</strong> <strong>Fund</strong> Golf tournaments also made a profound<br />

commitment to fight cancer and each raised $100,000 or more. <strong>The</strong>y include:<br />

• <strong>The</strong> Mutual <strong>Fund</strong>s Against Cancer Golf Classic, raising more than<br />

$200,000.<br />

• <strong>The</strong> <strong>Jimmy</strong> <strong>Fund</strong>/UNICCO Golf & Tennis Classic, raising $140,000.<br />

• <strong>Jimmy</strong> <strong>Fund</strong> Players Tournament, raising more than $130,000.<br />

• Kristin’s <strong>Fund</strong> 5th Annual Golf Tournament, raising $105,000.<br />

• 13th Annual David B. Perini, Jr. Memorial Golf Tournament, raising<br />

more than $100,000.<br />

<strong>Jimmy</strong> <strong>Fund</strong> Golf is well on its way to completing another successful season,<br />

bringing golf lovers together on the green to make a difference in the<br />

lives of cancer patients around the world.<br />

Left to right: Bonnie Hamill, Jessie Hoffman, Institute Trustees Jim and Barbara<br />

Sadowsky, and Jackie Hoffman celebrate at the Basketball Hall of Fame following<br />

the 26th Annual <strong>Jimmy</strong> <strong>Fund</strong> Golf Tournament/Jeffrey Vinick Memorial.<br />

Epsteins champion Women’s Cancers Program investigator<br />

True to its name, Champion Exposition Services has<br />

designated its fourth major gift in as many years to<br />

help Dana-Farber win the battle against women’s cancers.<br />

This year’s Champion Exposition Services’ Investigator<br />

Award—a $100,000 gift made possible by<br />

Mark and Eileen Epstein—provides DFCI’s<br />

Akila Viswanathan, MD, MPH, with the<br />

funding necessary to explore lifestyle risk<br />

factors for endometrial cancer, which affects<br />

the lining of the uterus.<br />

“<strong>The</strong> work being done today at Dana-<br />

Farber continues a long history of extraordinary progress,”<br />

said Mark Epstein, Champion’s founder, president, and<br />

CEO. “We believe that the Women’s Cancers Program is a<br />

perfect example of that development.”<br />

Through their Middleboro, Mass.-based company, which<br />

specializes in organizing tradeshows and events, the<br />

Epsteins have begun a tradition by generously supporting<br />

researchers in Dana-Farber’s Women’s Cancers Program<br />

year after year. <strong>The</strong>ir most recent gift will allow<br />

Viswanathan to delve into the effects of smoking, exercise,<br />

and aspirin use on endometrial cancer.<br />

“It is an honor to receive this prestigious award,” said<br />

Viswanathan. “<strong>The</strong> support provided by Champion<br />

Exposition Services and the Epsteins will be invaluable to<br />

my research into endometrial cancer.”<br />

J. Dirk Iglehart, MD, director of DFCI’s Women’s<br />

Cancers Program, also recognizes the far-reaching importance<br />

of the Champion Exposition Services’ Investigator<br />

Award. “Ultimately, Dr. Viswanathan’s research will contribute<br />

significantly to advancing knowledge of all<br />

women’s cancers,” he said.<br />

Thanks to the latest gift from Champion<br />

Exposition Services, Dana-Farber’s Akila<br />

Viswanathan, MD, MPH, is exploring lifestyle<br />

risk factors for endometrial cancer.<br />

4 <strong>Impact</strong> <strong>Summer</strong> <strong>2005</strong>


Dyson Foundation gift supports breast cancer research<br />

Eric Winer, MD, is researching new treatment<br />

approaches for women with basal-like cancers whose<br />

tumors have been resistant to hormonal therapy.<br />

Research into an aggressive<br />

form of breast cancer that<br />

claimed the life of Anne<br />

Dyson, MD, in 2000 will be supported<br />

by a new gift of $750,000<br />

by the New York-based Dyson<br />

Foundation. Established in 1957<br />

by Anne’s parents, Charles and<br />

Margaret, the foundation’s newest<br />

gift also gives momentum to Dana-<br />

Farber’s planned comprehensive<br />

capital campaign. <strong>The</strong> cutting-edge<br />

investigations will be led by Eric<br />

Winer, MD, director of DFCI’s<br />

Breast Oncology Center.<br />

Dyson worked as a pediatrician<br />

and was well-connected to Dana-<br />

Farber, having served as a trustee<br />

before becoming a patient of<br />

Winer’s. “Annie was bright, creative,<br />

enormously empathetic, and very<br />

funny,” said Winer. “I had a great<br />

deal of admiration for her.”<br />

Winer and his colleagues will use<br />

this gift to focus on basal-like, or triple negative, cancers,<br />

which account for 10–15 percent of all breast tumors. <strong>The</strong>se<br />

forms of breast cancer are characterized by tumors that are<br />

resistant to hormonal therapy.<br />

“New treatment approaches are desperately needed for<br />

women who have basal-like cancers,” Winer explained.<br />

“With the Dyson Foundation’s support, we will be able to<br />

extend our research in this area.”<br />

Stalwart advocate<br />

<strong>The</strong> Dyson Foundation has been a stalwart advocate of<br />

research at DFCI. Now run by Anne’s brother, Robert<br />

Dyson, the foundation also established a chair in pediatrics<br />

at the Institute in memory of their mother, Margaret M.<br />

Dyson, who died of ovarian cancer.<br />

This David G. Nathan Chair in Pediatrics, named after<br />

DFCI President Emeritus David G. Nathan, MD, and now<br />

held by Stuart Orkin, MD, chair of Pediatric Oncology, was<br />

followed by the 2001 establishment of the Anne E. Dyson<br />

Chair in Women’s Cancers, now held by J. Dirk Iglehart,<br />

MD, director of Dana-Farber’s Women’s Cancers Program.<br />

“We are honored to be able to help Dr. Winer in the<br />

thoughtful approach he is bringing to the future of breast<br />

cancer research,” said Robert Dyson.<br />

Nantucket “fun-raiser” garners<br />

$500,000-plus for Dana-Farber<br />

Fun and fundraising<br />

went hand-in-hand<br />

at the second annual<br />

“Boogie on Low Beach”<br />

event hosted by Institute<br />

Trustee George Cloutier<br />

in Nantucket, Mass. <strong>The</strong><br />

event raised more than<br />

$500,000 for Dana-Farber’s<br />

lifesaving mission, thanks to<br />

the generosity of Cloutier<br />

and his guests.<br />

“I’m thrilled that this<br />

event has been so successful<br />

so quickly,” said Cloutier.<br />

“I can’t thank my Nantucket<br />

neighbors and our terrific<br />

sponsors enough.”<br />

Some 650 guests dined<br />

Institute Trustee George Cloutier (left) welcomed<br />

nearly 650 guests at his fun-filled fete<br />

benefiting Dana-Farber. Cloutier's guest of<br />

honor was Boston Red Sox President and CEO<br />

Larry Lucchino (right).<br />

and danced under a tent at Cloutier’s Siasconset home on the night of<br />

July 22. Intercontinental Real Estate Corporation, a real estate investment<br />

manager and developer, was the event’s principal underwriter.<br />

WCVB-TV’s Natalie Jacobson served as master of ceremonies. Dozens<br />

of local and Boston businesses contributed fabulous prizes to both live<br />

and silent auctions. Items up for bid included lunch for three with<br />

Jack Welch at Boston restaurant No. 9 Park; a five-night stay valued at<br />

$15,000 donated by the luxury destination club Dream Catcher; a Palm<br />

Beach, Fla., weekend with a stay at a waterfront mansion; a round of golf<br />

and lunch at Mar-a-Lago; and a private dinner party prepared by celebrity<br />

chef Todd English.<br />

<strong>The</strong> event honored Larry Lucchino, president and CEO of the Boston<br />

Red Sox and a two-time cancer survivor treated at DFCI. “It was my privilege<br />

to welcome Larry to Nantucket and celebrate his efforts for both<br />

Dana-Farber and the Red Sox,” said Cloutier.<br />

<strong>The</strong> evening also benefited Nantucket Cottage Hospital’s Community<br />

and Home Health Department.<br />

Swimmers make a splash<br />

in the fight against cancer<br />

On July 22, 45 swimmers, including seven Olympians, put their<br />

best strokes forward in the 10th annual Boston Harbor Island<br />

Swim. Dedicated men and women broke through the waves of<br />

chilly Boston Harbor in a 22-mile relay race starting and ending at<br />

Rowes Wharf. <strong>The</strong> following day, more than 100 participants<br />

made a mad dash for the sea and took part in the Nantasket<br />

Beach Swim, completing either a half-mile or one-mile course.<br />

<strong>The</strong> two days of aquatic events were hosted by Boston’s<br />

Swim Across America program and provided determined swimmers<br />

a chance to improve life after cancer for survivors of the disease.<br />

Together, their efforts raised $180,000 for the David B.<br />

Perini, Jr. Quality of Life Clinic at Dana-Farber.<br />

<strong>Impact</strong> <strong>Summer</strong> <strong>2005</strong><br />

5


Rick Corman continues to “red flag”<br />

multiple myeloma<br />

Rick Corman’s latest gift of $250,000<br />

has brought his philanthropy to Dana-<br />

Farber across the $1 million mark—<br />

and he says this is just the beginning. Corman<br />

supports multiple myeloma research by<br />

Kenneth Anderson, MD, Paul Richardson,<br />

MD, and their colleagues in DFCI’s Jerome<br />

Lipper Multiple Myeloma Center.<br />

Diagnosed with multiple myeloma in 2001,<br />

Corman vowed to give $250,000 annually as<br />

long as he continues his successful fight<br />

against the rare blood cancer. For four years,<br />

Corman, clad in a bright red blazer, has handdelivered<br />

his gift to Dana-Farber, displaying<br />

confidence in and admiration for the physician-scientists<br />

in the Lipper Center.<br />

“I’m in business and I’ve found that money<br />

motivates many people, but not this research<br />

team,” said Corman, owner and founder of<br />

Over four years, Rick Corman has given<br />

$1 million to DFCI to spur development of<br />

effective multiple myeloma therapies.<br />

Nicholasville, Ky.-based RJ Corman Railroad,<br />

LLC. “<strong>The</strong>y are driven by something different—a<br />

passion to kill the disease before it<br />

kills us.”<br />

Corman’s philanthropy is inspired by the<br />

remarkable advances Anderson, Richardson,<br />

and fellow DFCI investigator Teru<br />

Hideshima, MD, PhD, have made against<br />

multiple myeloma. “<strong>The</strong>y have changed treatment<br />

in extraordinary ways.”<br />

For its part, the Lipper Center team agrees<br />

that Corman has helped spur progress. “Rick<br />

has become both a dear friend and a patient<br />

loved by all,” said Richardson. “His courage<br />

and commitment have been simply tremendous,<br />

and his generosity of spirit is inspirational.”<br />

Anderson says, “His kindness has<br />

helped caregivers and patients alike. We are<br />

lucky to have him on our team!”<br />

Aaron Foundation gift funds<br />

groundbreaking Kinase Project<br />

Send a message of hope<br />

this holiday season<br />

Since its establishment, the Aaron Foundation has been offering<br />

financial support to organizations and programs that make a<br />

positive impact in the world of education, culture, and science.<br />

Most recently, the foundation turned this altruistic focus to Dana-<br />

Farber with a $100,000 grant directed toward the Institute’s Kinase<br />

Project. This revolutionary research initiative aims to probe the genetic<br />

mutations that lead to cancer development<br />

and identify potential drugs to target<br />

these specific anomalies.<br />

“This research has far-reaching and crossfunctional<br />

potential, as its results could lead<br />

to a better understanding of a number of<br />

cancers,” said Aaron Foundation Trustee<br />

James Rabb, MD. “With the lifesaving<br />

possibilities so great, we see it as a good<br />

place to put our support.”<br />

“<strong>The</strong> hope is that this research will<br />

lead in the direction where it can do<br />

the most good—helping people overcome<br />

their diseases,” added Rabb’s<br />

David Livingston, MD, is leading DFCI’s cousin and fellow foundation trustee,<br />

Kinase Project, a pioneering research Jane Rabb, PhD.<br />

endeavor set to change the future of<br />

Led by David Livingston, MD, deputy<br />

cancer care and research.<br />

director of the Dana-Farber/Harvard<br />

Cancer Center and the Emil Frei Professor of Genetics and Medicine at<br />

Harvard Medical School, along with DFCI colleagues Matthew<br />

Meyerson, MD, PhD, and William Sellers, MD, this groundbreaking<br />

study will specifically examine some 150 different kinases, or cell<br />

enzymes, that have been found to aid cancer development when mutated.<br />

“This generous gift from the Aaron Foundation is important<br />

in helping us move forward with this critical research. Our overarching<br />

goal is to make available to cancer patients new treatments<br />

that are safer and more effective than the ones currently available,”<br />

said Livingston.<br />

Show your commitment to fighting cancer by purchasing<br />

a box of holiday greeting cards. All proceeds will benefit<br />

Dana-Farber’s lifesaving mission.<br />

Visit www.jimmyfund.org/holiday to view a selection of festive designs<br />

and order your cards, or call Charles Savicki at (617) 632-5420.<br />

CHAMPION<br />

A WINNING CAUSE<br />

Get into the spirit of the season. Choose from these one-of-a-kind<br />

Boston Red Sox and New England Patriots collectible ornaments.<br />

All proceeds from these limited edition pieces will benefit the<br />

<strong>Jimmy</strong> <strong>Fund</strong> and Dana-Farber's lifesaving mission. To order,<br />

please visit us online at www.jimmyfund.org/holiday or call<br />

Charles Savicki at (617) 632-5420.<br />

(ornament size: approximately 2.5” x 3”)<br />

6 <strong>Impact</strong> <strong>Summer</strong> <strong>2005</strong>


Need the perfect gift? Visit www.dana-farber.org/celebration-tribute.<br />

Sacklers steer support for rare cancer<br />

Raymond Sackler, MD, and his wife,<br />

Beverly, are international philanthropists<br />

who have long championed the arts and<br />

sciences. One scientific area they have specifically<br />

supported has been research into carcinoid<br />

and neuroendocrine tumors, rare cancers<br />

that do not typically attract significant funding.<br />

With the help of their Chief Scientific<br />

Officer Arnold Levine, PhD, the couple have<br />

assembled the foremost talent in the field.<br />

<strong>The</strong>ir interest led them to two noted Dana-<br />

Farber investigators: Matthew Meyerson,<br />

MD, PhD, and Matthew Kulke, MD. After<br />

initially supporting these scientists’ work in<br />

2003, the Sacklers have given new gifts of<br />

$500,000 and $250,000 to Meyerson and<br />

Kulke, respectively.<br />

“Drs. Meyerson and Kulke have proposed<br />

and partially accomplished goals that will significantly<br />

contribute to the basic science and<br />

clinical understanding of carcinoid and neuroendocrine<br />

cancers,” said Evan Vosburgh, MD, executive director of the<br />

Raymond and Beverly Sackler Foundation. “We hope that their work will<br />

help educate and motivate others to pursue research in this area, and that they<br />

will be successful at obtaining continued support to expand their research.”<br />

With continued support from Raymond and Beverly Sackler, DFCI’s<br />

Matthew Kulke, MD, (left) and Matthew Meyerson, MD, PhD,<br />

(right) are uncovering the genetic causes of neuroendocrine tumors.<br />

Delving deeper<br />

<strong>The</strong> Sacklers’ backing has led Meyerson and his<br />

team to uncover the function of once-mysterious<br />

proteins that play a critical role in the development<br />

of neuroendocrine cancer. <strong>The</strong>y studied tumor<br />

suppressor proteins that normally prevent neuroendocrine<br />

cancer but are inactivated in the tumors.<br />

Additionally, they found that two such proteins,<br />

menin and parafibromin, control gene activity and<br />

that this activity is deficient in the tumors.<br />

“This discovery opens new opportunities for the<br />

treatment of neuroendocrine tumors and for cancer<br />

therapies more generally,” said Meyerson.<br />

For Kulke, early support from the Sacklers<br />

helped him to build a database of neuroendocrine<br />

patients’ clinical information and blood and tumor<br />

samples. With the couple’s new gift, Kulke’s team<br />

is leveraging this repository, which now comprises<br />

more than 250 patients, to pinpoint the pathways<br />

involved in tumor development and uncover clues<br />

for treatment strategies.<br />

“Through their early support of Dana-Farber’s neuroendocrine tumor<br />

research, the Sacklers planted a seed that has rapidly grown and is already bearing<br />

fruit,” said Kulke. “We are incredibly grateful for their initial and continuing<br />

support of our efforts.”<br />

Verizon <strong>Jimmy</strong> <strong>Fund</strong> Scooper Bowl<br />

dishes up enthusiastic support<br />

Thousands of ice cream lovers<br />

flocked to the Verizon <strong>Jimmy</strong><br />

<strong>Fund</strong> Scooper Bowl June 7, 8,<br />

and 9 on Boston’s City Hall Plaza to<br />

indulge in their favorite frozen treats<br />

and to support New England’s favorite<br />

charity. <strong>The</strong> 23rd annual outdoor festival<br />

kicked off the lazy, hazy days of<br />

summer in grand style by raising its<br />

largest amount ever—more than<br />

$190,000—for the <strong>Jimmy</strong> <strong>Fund</strong> and<br />

Dana-Farber.<br />

<strong>The</strong> all-you-can-eat event attracted<br />

people of all ages, from hungry city<br />

workers enjoying their lunchtime<br />

breaks to schoolchildren holding<br />

hands on class outings. This year, they<br />

had their pick of more than 65 flavors<br />

of ice cream, frozen yogurt,<br />

and sorbet, including “Curse<br />

Reversed,” which celebrates the world<br />

championship Boston Red Sox,<br />

“Baseball Nut,” “Fenway Fudge,”<br />

“Thunder’N’Lightning,” and the<br />

“Last Straw,” provided by 10 generous<br />

companies (see sidebar).<br />

“This is always a wonderful event,<br />

and we are grateful to the people of<br />

Boston for welcoming the Scooper<br />

Bowl year after year with such enthusiasm,”<br />

said Mike Andrews, chairman of<br />

the <strong>Jimmy</strong> <strong>Fund</strong>. “We are especially<br />

thankful to the participating companies,<br />

which contributed more than<br />

10,000 gallons of ice cream, and to<br />

Verizon and all our sponsors for making<br />

this event a great success.”<br />

Title Sponsor: Verizon<br />

Vendors:<br />

Baskin-Robbins<br />

Ben & Jerry’s<br />

Brigham’s /Élan<br />

Cold Stone Creamery<br />

Edy’s Grand Ice Cream<br />

Garelick Farms<br />

Good Humor-Breyer’s Ice Cream<br />

Häagen-Dazs ®<br />

Blue skies and soaring temperatures made the<br />

Scooper Bowl the place to be for (left to right)<br />

Tykera and Isis Williams.<br />

Thank you to our generous supporters<br />

H.P. Hood<br />

Kemps ®<br />

In-kind Sponsors:<br />

Champion Expo Nationwide<br />

GE Capital<br />

Poland Spring<br />

Solo Cup Company<br />

Media Sponsors:<br />

Boston.com<br />

Community Newspaper Company<br />

Sunday, October 9, <strong>2005</strong><br />

B.A.A. HALF MARATHON<br />

Presented by Dana-Farber Cancer Institute and the <strong>Jimmy</strong> <strong>Fund</strong><br />

You are invited to join the Dana-Farber Runners in the race<br />

toward the ultimate finish line: a world without cancer.<br />

For more details and online registration information, log on to www.jimmyfund.org/half-marathon or call (617) 632-1970.<br />

<strong>Impact</strong> <strong>Summer</strong> <strong>2005</strong> 7


<strong>Impact</strong> is now available online at www.dana-farber.org/impact.<br />

Stop & Shop Triple Winner Game, continued from page 1<br />

received a scratch ticket guaranteed to win them food products, gift cards, or<br />

cash prizes up to $10,000. This win-win scenario, along with the support of the<br />

promotion’s co-sponsor, the Boston Red Sox, has propelled the promotion to<br />

become the <strong>Jimmy</strong> <strong>Fund</strong>’s most successful corporate fundraiser.<br />

A winning cause<br />

<strong>The</strong> company’s contributions to the Stop &<br />

Shop Clinic since its establishment have made<br />

a tremendous impact in Dana-Farber’s battle<br />

against pediatric brain tumors. Fueled by Stop &<br />

Shop’s generosity, the clinic has evolved over the last<br />

eight years into what is widely regarded to be the<br />

most comprehensive pediatric brain cancer center<br />

operating in the world today.<br />

Under the leadership of DFCI’s Mark Kieran, MD,<br />

PhD, director of Pediatric Medical Neuro-Oncology, a dedicated team of neurologists,<br />

oncologists, researchers, and support staff works tirelessly to break<br />

through the mysteries that surround this terrible disease in an effort to develop<br />

therapies that will translate into lives saved.<br />

Fueled by Stop & Shop’s resources, the center has created a number of cuttingedge<br />

programs designed to heal patients everywhere. One<br />

recent initiative was the establishment of a laboratory at<br />

Dana-Farber that utilizes the expertise of the Institute’s<br />

researchers while tapping into the knowledge of pediatric<br />

brain cancer specialists and scientists across the globe.<br />

This integration of resources has the potential to lead<br />

to the scientific breakthroughs that can be rendered<br />

into therapies for patients at a more rapid rate.<br />

“Thanks to Stop & Shop, we have been able to<br />

translate multiple discoveries into a better understanding of<br />

pediatric brain tumors, discoveries that would not have happened without their<br />

continued support over the last 15 years,” said Kieran. “Without Stop & Shop,<br />

all of the groundbreaking work now being conducted every day would not<br />

be possible.”<br />

Caring for Carcinoid<br />

Foundation links lab, clinic<br />

in search of a cure<br />

<strong>The</strong> Caring for Carcinoid Foundation has given $500,000<br />

to support the laboratory research of DFCI’s Ramesh<br />

Shivdasani, MD, PhD. This funding follows an earlier<br />

gift of $250,000 to support the clinical research of Dana-Farber’s<br />

Matthew Kulke, MD. Together, these two gifts connect the work<br />

from the lab and clinic.<br />

<strong>The</strong> foundation created this link to rapidly achieve its mission<br />

to discover a cure for carcinoid. At<br />

age 29, Nancy O’Hagan was diagnosed<br />

with this rare gastrointestinal<br />

neuroendocrine cancer. She<br />

and her husband, Patrick, founded<br />

the non-profit foundation in<br />

December 2004.<br />

“<strong>The</strong> Caring for Carcinoid<br />

Foundation simultaneously funds<br />

genetic, molecular, and clinical<br />

research,” said Nancy. “Lab-clinic<br />

collaboration brings together multiple<br />

disciplines to foster creativity<br />

Ramesh Shivdasani, MD, PhD, is determining and insight in each area of<br />

how normal cells might transform into neuroendocrine<br />

tumors, thanks to support from<br />

research, and it will ultimately<br />

the Caring for Carcinoid Foundation. accelerate the path to a cure for<br />

carcinoid cancer.”<br />

Experts now believe that future cures for cancer will be in the<br />

form of targeted therapies. <strong>The</strong>se therapies require first that<br />

cancer is understood at the level of the target cell. <strong>The</strong> foundation’s<br />

gift will make this type of research possible. Shivdasani’s<br />

lab will map the molecular basis and biological pathways of<br />

normal gastrointestinal (GI) cell development and differentiation.<br />

Such a map will enable him to determine how normal GI<br />

cells become malignant.<br />

By bringing this science to neuroendocrine tumors, he aims<br />

to outline the key pathways of neuroendocrine cell growth.<br />

Shivdasani’s research will link with Kulke’s research to yield<br />

innovative, targeted therapies.<br />

“<strong>The</strong> Caring for Carcinoid Foundation recognizes that<br />

Dana-Farber is unique among cancer institutes for fostering<br />

this partnership,” Shivdasani said. “It is our hope that by<br />

working collaboratively, we will identify potential drug targets<br />

to treat this disease.”<br />

New York Evening opens<br />

doors to novel research<br />

On June 8, Institute Trustee David Dechman welcomed<br />

Dana-Farber supporters from the metropolitan New York<br />

area for an evening of fellowship at the New York Yacht<br />

Club. Above: Evening host Dechman greeted <strong>Jimmy</strong> <strong>Fund</strong><br />

Visiting Committee member Terry Bovin (right) and featured<br />

speaker Karen Albritton, MD, (left) director of Dana-Farber’s<br />

newly established Adolescent and Young Adult (AYA)<br />

Oncology Program.<br />

Guests had the unique opportunity to learn about an<br />

emerging area of cancer research directly from a distinguished<br />

physician-scientist. In her presentation entitled,<br />

“A New Focus: <strong>The</strong> Lost Generation of Cancer Patients,”<br />

Albritton explained how the AYA Program is leading the<br />

way to improve treatment options for patients ages 15–40<br />

and working to address the unique needs of this group.<br />

NEED THE<br />

perfect<br />

GIFT?<br />

Look No Further<br />

Celebration and Tribute Gifts are a unique way to<br />

remember someone special or to celebrate birthdays,<br />

weddings, anniversaries, and other occasions while<br />

supporting Dana-Farber’s lifesaving work.<br />

Make a gift of $25 or more, and we’ll send a personalized<br />

greeting card to the special person of your choice within 24 hours.<br />

Visit www.dana-farber.org/celebration-tribute<br />

to learn more, or call Kim Goff at (617) 632-3146.<br />

8 <strong>Impact</strong> <strong>Summer</strong> <strong>2005</strong>


Dodge gift bolsters support for<br />

“lost generation” of patients<br />

Receiving a cancer diagnosis means<br />

confronting complicated emotions<br />

and difficult decisions. This diagnosis<br />

can be especially difficult for young<br />

adults who are facing other life changes<br />

such as completing college or entering<br />

the workforce.<br />

Active members of the Dana-Farber<br />

community, Institute Trustee Steven<br />

Dodge and his wife, Anne, understand the<br />

unique challenges faced by cancer patients<br />

ages 15–40 and their families. <strong>The</strong>ir<br />

recent gift of $500,000 supports DFCI’s<br />

new Adolescent and Young Adult (AYA)<br />

Oncology Program, which engenders<br />

research that is changing how physicians<br />

care for younger patients, and provides<br />

momentum for the Institute’s planned<br />

comprehensive capital campaign.<br />

“Anne and I have long supported<br />

the <strong>Jimmy</strong> <strong>Fund</strong>’s youthful spirit and<br />

commitment to Dana-Farber’s youngest<br />

patients,” said Steven Dodge. “By helping<br />

fund the AYA Program, we hope to<br />

reach out to an underserved population<br />

and make a difference in the lives of<br />

young adults.”<br />

Directed by Karen Albritton, MD, the<br />

AYA Program is examining how one-sizefits-all<br />

approaches to treating cancer<br />

patients may create what Albritton calls<br />

a “lost generation.” Albritton’s research<br />

points to alarming deficits in the treatment<br />

of adolescents and young adults<br />

with this disease. She suggests this<br />

younger age group’s cancer problem<br />

(approximately 70,000 diagnoses per<br />

year in the U.S.) has been overshadowed<br />

by the sheer volume of cancers in older<br />

populations (more than 700,000 diagnoses<br />

annually).<br />

“Cancer treatment specifically focused<br />

on adolescents and young adults has typically<br />

lagged behind that of their older and<br />

<strong>The</strong> AYA Program at Dana-Farber is committed<br />

to improving treatment for younger<br />

cancer patients like Mike Violandi, who was<br />

diagnosed with leukemia at age 30.<br />

younger counterparts,” Albritton said.<br />

“<strong>The</strong>re has been an unmet need for targeted<br />

clinical and research programming<br />

and attention to the unique needs of this<br />

generation. With the Dodges’ gift, we can<br />

take a leadership role in providing services<br />

to this age group and begin to reduce<br />

these inequities.”<br />

With support like the Dodges’, the AYA<br />

Program will help return these patients to<br />

the important task of embarking on their<br />

journeys through adult life.<br />

<strong>Jimmy</strong> <strong>Fund</strong> Regatta sets<br />

a course for curing cancer<br />

Employers, employees<br />

unite to fight cancer<br />

This year,<br />

thousands of<br />

individuals<br />

helped fight cancer<br />

by giving to Dana-<br />

Farber and the<br />

<strong>Jimmy</strong> <strong>Fund</strong> at<br />

work. <strong>The</strong> combined<br />

effort of these<br />

generous employees<br />

and nearly 120 host<br />

companies raised<br />

$500,000 for cutting-edge<br />

research letter carrier with the United States<br />

Lisa Sims-Okundaye, a 19-year<br />

and compassionate Postal Service, has been a steadfast<br />

supporter of Dana-Farber’s workplace<br />

patient care through<br />

giving campaign.<br />

DFCI’s annual<br />

workplace giving campaign.<br />

“During our annual United Way campaign, NSTAR<br />

encourages our employees to make contributions to the<br />

charitable causes that are important to them and their<br />

families, including great organizations like Dana-Farber,”<br />

said NSTAR CEO and Institute Trustee Thomas May.<br />

“This is a great way for NSTAR to give back to the communities<br />

we serve.”<br />

People as far away as Hawaii made gifts ranging from<br />

$5–$25,000 through employer-sponsored fund drives,<br />

United Way designations, and one-time and monthly<br />

gifts made directly to DFCI. Additionally, government<br />

employees, including those serving overseas in the<br />

Armed Forces, participated through the Combined<br />

Federal Campaign (CFC).<br />

“With my gifts, I hope that Dana-Farber’s doctors can<br />

wipe out cancer altogether,” said Lisa Sims-Okundaye, a<br />

letter carrier with the United States Postal Service who<br />

has supported DFCI through the CFC for more than<br />

10 years. “I don’t like to see people sick, especially kids.<br />

My hope is that these patients will get better so that<br />

they can enjoy their lives.”<br />

Consider setting up a workplace giving campaign to<br />

benefit Dana-Farber at your place of employment or let us<br />

help you increase participation in your United Way campaign.<br />

Visit us online at www.dana-farber.org/give-atwork,<br />

or call Maxine Neil at (617) 632-3492.<br />

give from your heart<br />

“Dana-Farber helped extend my<br />

mother’s life 20 years after her<br />

diagnosis. Naming a chair was<br />

the perfect way to memorialize<br />

her and honor my family<br />

in a lasting way.”<br />

— Bill Murphy<br />

<strong>The</strong> sailing community turned out in full<br />

force for the inaugural <strong>Jimmy</strong> <strong>Fund</strong> Regatta,<br />

held in Newport, R.I., on June 4–5.<br />

Presented by financial services company<br />

Northern Trust and co-chaired by Nancy<br />

Stratton and David Ford, the two-day<br />

racing event featured avid yachters and<br />

boating enthusiasts who took to the high<br />

seas for a great cause—helping the <strong>Jimmy</strong><br />

<strong>Fund</strong> and Dana-Farber make waves against<br />

cancer. With a highly competitive regatta,<br />

a fun-filled “Sail for <strong>Jimmy</strong>” race, and a<br />

dinner and awards presentation, the successful,<br />

first-time event brought in a<br />

fundraising total of more than $180,000.<br />

Left to right: DFCI Chief of Staff<br />

Stephen E. Sallan, MD; Institute Trustee<br />

Charles A. Dana III, owner of <strong>Jimmy</strong> <strong>Fund</strong><br />

Regatta host site Newport Shipyard; and<br />

<strong>Jimmy</strong> <strong>Fund</strong> Chairman Mike Andrews<br />

gathered together as the sun set on the<br />

opening day of the sailing event.<br />

Cancer has touched all of us. Name a chair in the<br />

<strong>Jimmy</strong> <strong>Fund</strong> Auditorium and create a lasting tribute<br />

to a family member, friend, or colleague.<br />

Your gift of $10,000 forever links that special person<br />

to DFCI’s lifesaving mission.<br />

To read more personal stories or to name a chair<br />

online, visit www.jimmyfund.org/chairs or call<br />

Maxine Neil at (617) 632-3492.<br />

Your gift of $10,000 can be made in two payments.<br />

Nearly half of the chairs have been named.<br />

<strong>Impact</strong> <strong>Summer</strong> <strong>2005</strong><br />

9


Myeloma Research <strong>Fund</strong> promotes national collaboration<br />

<strong>The</strong> Myeloma Research <strong>Fund</strong> is enabling<br />

Kenneth Anderson, MD, and his colleagues<br />

at Dana-Farber to work collaboratively<br />

with other national cancer<br />

experts to increase the pace of discovery.<br />

When Lew Aronson was in his mid-30s, he was<br />

treated for the rare blood cancer multiple<br />

myeloma. This experience inspired him to<br />

raise $2 million and establish the Myeloma Research<br />

<strong>Fund</strong> (MRF), a catalyst for collaboration<br />

between leading<br />

national researchers.<br />

Now, Dana-Farber’s Kenneth<br />

Anderson, MD, director of the<br />

Jerome Lipper Multiple Myeloma<br />

Center at DFCI and the Kraft<br />

Family Professor of Medicine at<br />

Harvard Medical School, has<br />

been awarded his fourth consecutive MRF grant. This<br />

new $190,000 gift, which brings the MRF’s cumulative<br />

funding to DFCI to $940,000, will help Anderson conduct<br />

important drug discovery and validation in concert<br />

with cancer experts across the country.<br />

“Working together with myeloma<br />

investigators in Florida and<br />

California … we can do more<br />

than any one center could<br />

do alone.”<br />

Aronson’s cancer went into remission following a bone<br />

marrow transplant in 2000. He explained that MRF’s goal<br />

is to find a cure—or method of infinite control—of multiple<br />

myeloma in the shortest practical period.<br />

“Dr. Anderson’s team combines<br />

basic scientific studies of the biochemical<br />

pathways involved in the survival<br />

and proliferation of the myeloma cell<br />

with clinical trials of new compounds<br />

which can interrupt those pathways,”<br />

said Aronson.<br />

Anderson firmly believes that collaborative<br />

approaches to research increase<br />

the pace of progress in identifying and validating new targeted<br />

therapies. “Thanks to the Myeloma Research <strong>Fund</strong>,<br />

our team is working together with myeloma investigators<br />

in Florida and California,” said Anderson. “Together, we<br />

can do more than any one center could do alone.”<br />

— Kenneth Anderson, MD<br />

PMC, continued from page 1<br />

As he has since 1980, PMC Founder<br />

and Executive Director Billy Starr<br />

takes on the challenging two-day<br />

course from Sturbridge to<br />

Provincetown, Mass.<br />

<strong>The</strong> next 25 rides<br />

After celebrating its 25th anniversary last year, the PMC is looking<br />

forward to making the next quarter century as successful as the last.<br />

As always, this level of achievement depends on the riders’ passion and<br />

heartfelt commitment to the cause. <strong>The</strong> PMC is also expanding its<br />

programs to bring its fundraising for the <strong>Jimmy</strong> <strong>Fund</strong> to new heights.<br />

One such initiative is the PMC Kids Ride program, which encourages<br />

children to embrace philanthropy at an early age. This year, 1,500<br />

kids participated in 15 Kids<br />

Rides, which together raised a<br />

total of $150,000. “<strong>The</strong> Kids<br />

Rides are the future of the<br />

PMC,” Starr said.<br />

After the children graduate<br />

from the Kids Rides, Starr hopes<br />

the young cyclists will join the<br />

main event. Emily Bekenstein is<br />

a young rider who started participating<br />

in the PMC when she<br />

was 15 years old. This year<br />

marked her third PMC. Since<br />

2003, she has raised more than<br />

$72,000. Bekenstein’s parents,<br />

Anita and Josh, are longtime<br />

PMC cyclists; Josh is also a<br />

Dana-Farber trustee and PMC<br />

board member. As cyclists of all<br />

ages continue to rise to the<br />

challenge, the PMC’s important<br />

legacy will live on well<br />

into the future.<br />

<strong>The</strong> PMC is reaching out to<br />

additional supporters in another<br />

innovative way through its Many participants, like William Teseira of East Boston,<br />

Mass., ride to honor a loved one’s battle with cancer.<br />

Virtual Rider program, which<br />

enables people who do not ride<br />

over PMC weekend to travel a different route or participate in another<br />

activity to further the organization’s mission of funding cancer research.<br />

Sixty-one-year-old Dan Healey of Randolph, Mass., is a Virtual Rider<br />

who, in late May, set out to cycle across the country for the PMC. It was<br />

his second cross-country ride, but this time his focus lay solely on beating<br />

his brain cancer. Healey, a patient at Dana-Farber, knows firsthand<br />

how important it is to raise money for medical research.<br />

“Medical science has nearly eliminated polio and childhood leukemia,”<br />

Healey said. “Someday, we may be able to say that the PMC helped<br />

defeat cancer.”<br />

Katelynn’s Ride cycles<br />

past $500,000 mark<br />

Nearly 300 riders pedaled their way<br />

through Western Massachusetts on June 5<br />

for the fifth annual Katelynn’s Ride<br />

fundraiser. This virtual ride of the Pan-<br />

Massachusetts Challenge bike-a-thon is<br />

held annually in memory of Katelynn<br />

Battista, a Dana-Farber patient who lost<br />

her courageous battle with cancer in 1997<br />

at age 11.<br />

Organized by Katelynn’s parents,<br />

Michele and Domenic Battista, and event<br />

directors Steven Stark, Dan Williams, and<br />

Kim Zachary, the ride raised $125,000—an<br />

additional $4,000 came in after event<br />

day—for the <strong>Jimmy</strong> <strong>Fund</strong> this year, surpassing<br />

its five-year, $500,000 goal. This<br />

generous gift will support pediatric cancer<br />

research and care, and it will name a<br />

<strong>Jimmy</strong> <strong>Fund</strong> Clinic infusion room in<br />

Katelynn’s memory.<br />

Left to right: Dan Williams, Kim<br />

Zachary, Michele Battista, Steven Stark,<br />

and Domenic Battista celebrated Katelynn’s<br />

life and this year’s successful ride.<br />

STEP UP TO<br />

THE PLATE!<br />

Support your favorite baseball team and<br />

New England’s favorite charity by sporting<br />

the official <strong>Jimmy</strong> <strong>Fund</strong>/Boston Red Sox<br />

Massachusetts license plate on your car.<br />

Go to<br />

www.jimmyfund.org/plate<br />

to order your plate.<br />

10 <strong>Impact</strong> <strong>Summer</strong> <strong>2005</strong>


Log on to www.dana-farber.org and help conquer cancer.<br />

Smith Family Foundation<br />

grant advances study of<br />

new therapies<br />

Support for critical translational<br />

research efforts can be difficult to<br />

find, so DFCI’s Anthony Letai,<br />

MD, PhD, and Scott Armstrong, MD,<br />

PhD, are thankful to be advancing<br />

their cutting-edge work with Smith<br />

Family New Investigator Awards. <strong>The</strong><br />

two-year, $200,000 grants, established<br />

by the Richard and Susan<br />

Smith Family Foundation, will allow<br />

Letai and Armstrong to investigate<br />

improved treatments for chronic<br />

lymphocytic leukemia (CLL) and<br />

childhood leukemia, respectively.<br />

Begun by the foundation in 1991<br />

and administered by <strong>The</strong> Medical<br />

Foundation, the annual awards are<br />

bestowed upon promising scientists<br />

early in their careers, before they are<br />

eligible for major grant support.<br />

“We are particularly proud to<br />

support young scientists from Dana-<br />

Farber as Smith Family New<br />

Investigators,” said Institute Trustee<br />

Richard Smith, co-chair of the foundation’s<br />

board of trustees. “Translational<br />

research is Dana-Farber’s great strength,<br />

and research by Drs. Letai and Armstrong<br />

promises to lead the way to new leukemia<br />

therapies.” <strong>The</strong> Smith family is a longtime<br />

Institute supporter; the Richard A.<br />

and Susan F. Smith Laboratories at<br />

DFCI are named in their honor.<br />

Letai will use his grant to build on<br />

earlier research with his late DFCI colleague,<br />

Stanley J. Korsmeyer, MD, to<br />

identify chemical compounds targeting<br />

the molecule BCL-2, shown to block cell<br />

death, which may be candidates for clinical<br />

trials. Armstrong will put his award<br />

to work researching childhood leukemia’s<br />

development and using his findings to<br />

craft more effective treatments.<br />

Photo by Michael Thompson<br />

KEY TO THE CURE<br />

OCTOBER 28 AND 29<br />

Join Saks Fifth Avenue for our annual shopping event to support Key To <strong>The</strong> Cure,<br />

a charitable initiative to fight women’s cancers.<br />

A percentage of sales up to $1 million will be donated to local and national<br />

women’s cancer charities through the Women’s Cancer Research <strong>Fund</strong>,<br />

a program of the Entertainment Industry Foundation. To order the limited edition<br />

T-shirt designed by Diane von Furstenberg, or for more information about this event,<br />

call 888.771.2323 or visit saks.com. Mercedes-Benz USA, LLC will make a<br />

generous donation of $1 million to Saks Fifth Avenue’s Key To <strong>The</strong> Cure<br />

through the sale of 750 Signature Edition R-Class vehicles.<br />

Special thanks to Hilary Swank, the <strong>2005</strong> Ambassador for<br />

EIF’s Women’s Cancer Research <strong>Fund</strong> and Saks Fifth Avenue’s Key To <strong>The</strong> Cure.<br />

SAVING LIVES<br />

IS ALWAYS IN FASHION<br />

Anthony Letai, MD, PhD, (left) and<br />

Scott Armstrong, MD, PhD, (above, left)<br />

received Smith Family New Investigator<br />

Awards that will help advance their<br />

research into improved therapies for<br />

specific leukemias.<br />

Join QVC and the Fashion Footwear Association<br />

of New York and take a step toward eradicating<br />

breast cancer in the 12th annual Shoes on Sale ® .<br />

Choose from a wide array of designer and brandname<br />

shoes at half their suggested price. All proceeds<br />

benefit breast cancer research and education at<br />

Dana-Farber and other centers around the country.<br />

For more information contact:<br />

Sarah Curtis at (617) 632-5091<br />

or via e-mail at<br />

sarah_curtis@dfci.harvard.edu<br />

Style and hope meet on the runway<br />

High fashion and the battle against cancer took<br />

center stage on May 20 at the Hyatt Regency<br />

Boston during “Couture for Hope,” an<br />

elegant luncheon and fashion show to benefit the<br />

Women’s Cancers Program at Dana-Farber Cancer<br />

Institute. Hosted by Neiman Marcus and organized<br />

by Honorary Chair Susan Smith and event co-chairs<br />

Deborah First, Institute Trustee Patricia Franchi, and<br />

Boston Red Sox wives Kathryn Nixon and Karen<br />

Varitek, this event raised an impressive $160,000.<br />

Neiman Marcus has helped raise hundreds of thousands<br />

of dollars for cancer research and patient care<br />

and has been a generous supporter of numerous<br />

Dana-Farber events, including the kickoff party for<br />

the <strong>2005</strong> Palm Beach, Fla., fundraising season.<br />

“Neiman Marcus feels very strongly about givingback<br />

to the community,” said Lesley Greer, general<br />

On the eve of Couture for Hope, Boston Red Sox<br />

players Trot Nixon (second from left) and Jason Varitek<br />

and their wives, Kathryn Nixon (left) and Karen<br />

Varitek (right), hosted a private dinner for guests to<br />

meet designer Carolina Herrera (middle).<br />

manager and vice president of Neiman Marcus<br />

Boston. “Dana-Farber has such a tremendous impact<br />

on improving the lives of so many. It is our honor to<br />

support this cause.”<br />

Internationally renowned fashion designer<br />

Carolina Herrera lent the simple elegance of her<br />

designs to the highlight of the afternoon: an exclusive<br />

runway show and preview of her fall <strong>2005</strong> collection.<br />

Joyce Kulhawik, arts and entertainment anchor<br />

for Boston’s CBS4-TV, emceed the fashion show.<br />

She was also the recipient of the Susan F. Smith<br />

Inspiration Award, which is presented annually to<br />

individuals who motivate and improve the lives of<br />

those with cancer. Having battled the disease three<br />

times herself, Kulhawik is an inspiration to many<br />

and a strong advocate in the search for cures.<br />

<strong>Impact</strong> <strong>Summer</strong> <strong>2005</strong><br />

11


Register for an event at www.jimmyfund.org.<br />

Sherwood, Kotkowski, Maffei families establish<br />

enduring memorial<br />

When Daryl Layzer lost her battle with multiple myeloma, her family<br />

wanted to thank her team of Dana-Farber physicians—led by Kenneth<br />

Anderson, MD—and help ensure future patients received the same compassionate<br />

care and had effective new treatment options available to them.<br />

Layzer’s mother, Rosemary Kotkowski; husband, Jim Maffei; and sister and<br />

brother-in-law, Emily and Ned Sherwood, banded together to carry out this wish,<br />

giving $1 million to establish the Daryl E. Layzer <strong>Fund</strong> at DFCI in 1998. To expand<br />

this fund, the family recently made an additional $250,000 gift.<br />

“My father talked to me about giving back to those who come after us,” said<br />

Kotkowski. “I believe that the superb care Dr. Anderson gave my daughter was made<br />

possible because of the generosity of those who preceded her.”<br />

<strong>The</strong> Sherwoods could not agree more. <strong>The</strong>y said that Dana-Farber’s bench-to-bedside<br />

model gave Daryl the opportunity to benefit from best practices in the field of<br />

myeloma research while receiving personalized and loving care from Anderson and<br />

his team.<br />

Maffei added, “I saw what Daryl went through, and I want a better world for<br />

myeloma patients.”<br />

“We have three new myeloma drugs—Thalomid ® , Revlimid ® , and Velcade ® —as a<br />

result of the initial support from Daryl’s family,” said Anderson, director of DFCI’s<br />

Jerome Lipper Multiple Myeloma Center and the Kraft Family Professor of Medicine<br />

at Harvard Medical School. “This new gift will help us meet our goal of making<br />

available at least one new drug a year to treat patients.”<br />

Left to right: Ned and Emily Sherwood, Rosemary Kotkowski, and Jim<br />

Maffei believe that Kenneth Anderson, MD, and his DFCI colleagues<br />

are on the fast track to finding a cure for multiple myeloma.<br />

Jazz night hits a high note<br />

for Friends of Dana-Farber<br />

Nearly 300 guests dined and danced the<br />

evening away for a good cause on May 13<br />

at “A Night of Jazz,” hosted by the Friends<br />

of Dana-Farber Cancer Institute, an allvolunteer<br />

organization. <strong>The</strong> eclectic event,<br />

held at the State Room in Boston, raised<br />

more than $400,000 for cancer research<br />

and care through ticket sales and a tribute<br />

book honoring the Bekenstein family for<br />

its continued commitment to DFCI.<br />

Internationally recognized vocalist<br />

Lavay Smith & Her Red Hot Skillet Lickers,<br />

a star-studded eight-piece band, performed<br />

classic jazz and blues numbers in<br />

the authentic style of the 1940s and ‘50s.<br />

During dinner, attendees were treated to<br />

the smooth sounds of the Victor Mendoza<br />

Trio while enjoying panoramic views of<br />

Boston Harbor and the islands.<br />

Left to right: “A Night of Jazz” Cochairs<br />

Kelly Pesek and Maureen Champa<br />

celebrate the event’s resounding success.<br />

For more information about the Friends,<br />

visit www.dana-farber.org/how/friends.<br />

Oracle helps combat ER-negative breast cancer<br />

“Oracle’s funding of<br />

Dr. Brown’s work has<br />

produced very significant<br />

developments, year<br />

after year.”<br />

— Rosalie Gann<br />

Research by Dana-Farber’s Myles Brown, MD,<br />

into estrogen-receptor-negative (ER-negative)<br />

breast cancer caught the eye of Oracle<br />

Corporation. Impressed with his progress using a<br />

technology called RNA interference (RNAi), the<br />

world’s largest enterprise software company has now<br />

made its third $100,000 gift to<br />

help Brown combat this aggressive<br />

form of breast cancer.<br />

“Oracle’s funding of Dr. Brown’s<br />

work has produced very significant developments, year<br />

after year,” said Rosalie Gann, Oracle’s director of giving.<br />

“<strong>The</strong> recent mapping of the human genome and<br />

use of RNAi technology have multiplied the possibilities<br />

of his research exponentially.”<br />

ER-negative cancers account for about one-third<br />

of all breast cancers, or some 65,000 cases a year, in<br />

the United States. ER-negative tumors are so named because<br />

they do not have receptors, or special proteins, that bind<br />

to estrogen.<br />

While this form of the disease is currently difficult to<br />

treat, RNAi is enabling Brown to understand the causal<br />

factors and critical pathways involved in<br />

the growth and malignant behavior of<br />

ER-negative tumors. By eliminating the<br />

product of a specific gene and depriving<br />

the cell of the gene’s activity, RNAi provides<br />

researchers with an advantage in determining the<br />

course of future therapies.<br />

“This technology will ultimately lead to improvements in<br />

the prevention and treatment of these tumors,” said Brown,<br />

chief of Molecular and Cellular Oncology. “Oracle continues<br />

to make it possible for us to increase our understanding<br />

of the forces driving ER-negative breast cancer.”<br />

12 <strong>Impact</strong> <strong>Summer</strong> <strong>2005</strong>


Kimmel Foundation rewards<br />

two translational scientists<br />

<strong>The</strong> Sidney Kimmel Foundation for Cancer<br />

Research has given two $200,000 grants to a<br />

pair of Dana-Farber physician-scientists to<br />

advance their work and improve cancer therapies.<br />

Anthony Letai, MD, PhD, and Ruben Carrasco,<br />

MD, PhD, won prestigious Kimmel Translational<br />

Science Awards, created five years ago to support<br />

physicians who also conduct research.<br />

“<strong>The</strong> foundation recognizes that translational<br />

research is absolutely critical to improving treatment<br />

for cancer,” said Gary Cohen, MD, administrative<br />

director of the Kimmel Foundation. “We are<br />

pleased to support Dana-Farber and these excellent<br />

young physicians. Clearly, they were at the top of<br />

the applicant pool, and I know they will continue<br />

to do great work.” More than 200 researchers vied<br />

this year for the 15 grants the foundation awards<br />

annually to young scientists, including five designated<br />

for physician-scientists.<br />

Letai’s award will enable him to probe the<br />

strategies cancer cells employ to avoid death, and<br />

he will use these findings to develop new therapies.<br />

Carrasco’s prize will help him investigate<br />

specific genes implicated in the pathogenesis of<br />

multiple myeloma, a devastating hematological<br />

malignancy. He will also research genetic lesions<br />

to find novel therapeutic targets and markers to<br />

help diagnose and predict the course of the disease<br />

and treatment outcomes.<br />

“I am very grateful to the Kimmel Foundation<br />

not only for the practical, essential support they are<br />

providing for my research, but also for the honor<br />

they have bestowed in recognizing my laboratory’s<br />

work with this award,” said Letai.<br />

Make Hope<br />

the Guest of Honor<br />

at Your Next Occasion<br />

In place of standard party or event<br />

favors, give a gift that will help find cures<br />

for cancer. Our Special Occasion Favors<br />

inform your wedding, shower, Bar/Bat<br />

Mitzvah, or party guests that a gift has<br />

been made to Dana-Farber in their honor.<br />

Order your Special Occasion Favors online<br />

at www.jimmyfund.org/favors<br />

or call Alicia Gallo at (617) 632-6099<br />

or (800) 52-JIMMY.<br />

Second victory against<br />

melanoma inspires gift<br />

<strong>The</strong> spot on Thalma Cohen de Gruszka’s chest X-ray was alarming. <strong>The</strong><br />

Caracas, Venezuela, native had defeated melanoma in 2000, and four<br />

years later seemed poised for a new battle against mesothelioma (a cancer<br />

of the lining of the lungs). Sent by her doctor to the United States to see specialists<br />

at Dana-Farber, Cohen de Gruszka learned the truth: <strong>The</strong> spot was actually<br />

an unusually located recurrence of melanoma. Her subsequent treatment by<br />

DFCI Melanoma Program Clinical Director F. Stephen Hodi, MD, together<br />

with her positive attitude and love of life, have put her on the road to a second<br />

victory against cancer.<br />

To thank Hodi for his exemplary care and to support his innovative<br />

immunotherapy studies, Cohen de Gruszka has established the $100,000<br />

Gruszka Cohen Family <strong>Fund</strong> for Melanoma Research.<br />

“I was very lucky to be able to come to the United States and to Dana-<br />

Farber,” said Cohen de Gruszka. “I hope this gift will help make treatments like<br />

Dr. Hodi’s available to those who cannot travel here to receive them.”<br />

<strong>The</strong> fund will bolster Hodi’s studies of cancer immunotherapeutics—treatments<br />

that utilize immune-stimulating compounds and a patient’s melanoma<br />

cells to launch a potent anti-tumor immune attack.<br />

“With a better understanding of the effects of different target/drug combinations,<br />

it will be possible to improve on the promising results already seen with<br />

these treatments,” said Hodi. “This support will go a long way toward bringing<br />

about this understanding.”<br />

Marathon Challenge says<br />

“thank you” to top fundraisers<br />

Each year, the Dana-Farber Marathon Challenge (DFMC) offers runners<br />

the opportunity to reach two personal milestones simultaneously—completing<br />

the legendary Boston Marathon ® while raising vital funds to support<br />

the lifesaving work of investigators in the Claudia Adams Barr<br />

Program in Innovative Basic Cancer Research at Dana-Farber. As each<br />

DFMC participant works diligently to raise the individual minimum of<br />

$2,500, there are several dozen team members who emerge to significantly<br />

surpass this point along the fundraising route, hoping to reach the<br />

ultimate finish line: the eradication of cancer.<br />

Those runners whose efforts yielded $10,000 or more in <strong>2005</strong> were<br />

recognized at the DFMC’s annual “10K Team” reception at Dana-Farber<br />

on June 29. <strong>The</strong> event paid tribute to these fundraising pacesetters<br />

(some of whom are pictured here) whose combined contribution of more<br />

than $1.2 million pushed the Marathon Challenge’s overall fundraising<br />

total to $3.4 million.<br />

Give Online<br />

It makes a world of difference to our patients<br />

F. Stephen Hodi, MD, is working to bring effective cancer vaccines to<br />

melanoma patients including Jeanne Myers (pictured here).<br />

Help Dana-Farber continue to make progress against cancer and save lives.<br />

Make your gift online today at www.jimmyfund.org or www.dana-farber.org.<br />

<strong>Impact</strong> <strong>Summer</strong> <strong>2005</strong><br />

13


Gillette expands commitment<br />

to prostate cancer care<br />

In 2004, <strong>The</strong> Gillette Company partnered with Dana-Farber<br />

to tackle racial disparities in prostate cancer screening by<br />

launching <strong>The</strong> Gillette Company Community Prostate Cancer<br />

Screening Program. With a $100,000 gift to DFCI’s Donald<br />

Kufe, MD, the company has now expanded its dedication<br />

to defeating the disease by supporting<br />

research into new treatments, as well.<br />

Gillette’s burgeoning commitment<br />

to Dana-Farber’s prostate cancer<br />

efforts complements the company’s<br />

extensive support for the care of<br />

women’s cancers through the Gillette<br />

Center for Women’s Cancers at<br />

DFCI. <strong>The</strong> prostate screening program,<br />

which uses the Institute’s Blum<br />

Family Resource Center Van to bring<br />

cancer information and testing services<br />

to underserved populations around<br />

<strong>The</strong> Gillette Company is teaming up with Boston, was among the company’s<br />

Donald Kufe, MD, to untangle the complex<br />

relationship between the protein<br />

first forays into prostate health.<br />

“<strong>The</strong> response to the screening program<br />

and the promise of Dr. Kufe’s<br />

MUC1 and prostate cancer.<br />

approach have inspired us to boost<br />

“<strong>The</strong> response to the<br />

our involvement in prostate cancer<br />

care,” said Gillette Vice President for<br />

screening program<br />

Civic Affairs Cathy Chizauskas.<br />

and the promise of<br />

Gillette’s backing will allow Kufe to<br />

examine the mechanisms by which<br />

Dr. Kufe’s approach have the mucous protein MUC1 contributes<br />

to prostate cancer develop-<br />

inspired us to boost our<br />

ment. <strong>The</strong> protein—which is overproduced<br />

in 60–70 percent of<br />

involvement in prostate<br />

cancer care.”<br />

prostate tumors—helps cancer cells<br />

resist radiation and chemotherapy.<br />

“I’m particularly interested to know<br />

— Cathy Chizauskas<br />

how MUC1 interferes with hormone<br />

therapy in prostate cancer,” says Kufe.<br />

“Understanding this, we can develop an assortment of tools to<br />

eliminate MUC1 and counter the resistance.”<br />

Family honors son’s<br />

memory with<br />

pediatric fellowship<br />

Scott and Heidi Smith’s personal battle against pediatric cancers<br />

started with the loss of their 4-year-old son Garrett. Through<br />

the Garrett B. Smith Foundation, the Smiths have enlisted Dana-<br />

Farber’s expertise to realize their vision of eradicating pediatric cancers<br />

by awarding a two-year, $100,000 Garrett B. Smith Term Fellowship<br />

to DFCI’s Charles Roberts, MD, PhD.<br />

“<strong>The</strong> foundation is our way of keeping Garrett’s memory burning<br />

brightly,” said Scott Smith, “and playing some small role in advancing<br />

the fight against children’s cancers.”<br />

Roberts’ fellowship is the ninth awarded nationwide by the Garrett B.<br />

Smith Foundation since 1996, and the first to be given to a Dana-Farber<br />

staff member. This support provides young scientists at established<br />

cancer centers the opportunity to pursue innovative research ideas.<br />

<strong>The</strong> Smiths were connected to Roberts by Robert Soiffer, MD, chief<br />

of Hematologic Malignancies and a longtime friend of Scott’s. “We’ve<br />

known each other since we were 12,” says Soiffer.<br />

“Scott and Heidi do their homework and know what they are looking<br />

for in a potential fellow,” said Soiffer. “I was very pleased to see how<br />

impressed they were with Charlie and his work.”<br />

Roberts’ research focuses on the potentially widespread cancer-causing<br />

capabilities of Snf5, a gene linked to aggressive pediatric tumors. “With<br />

the foundation’s support, I will be able to access the resources I need to<br />

build a fundamental understanding of Snf5’s newly appreciated role in<br />

cancer development,” said Roberts.<br />

<strong>The</strong> Smiths have also made a $50,000 gift to support lymphoma<br />

research at Dana-Farber.<br />

Established by Scott and Heidi Smith (above), the Garrett B. Smith<br />

Foundation is helping Charles Roberts, MD, PhD, gain new insights into the<br />

genetics of pediatric cancers.<br />

American Lung Association gives hope to cancer patients<br />

<strong>The</strong> American Lung Association ® (ALA) is committed<br />

to supporting the promise of national leaders in<br />

lung investigative work. To carry out this mission,<br />

the organization has presented its ALA/LUNGevity<br />

Foundation Research Grant to Dana-Farber’s Matthew<br />

Meyerson, MD, PhD. This $180,000 gift will fund<br />

research into adenocarcinoma, the most common form of<br />

lung cancer.<br />

“<strong>The</strong> results of Dr. Meyerson’s research project will help<br />

further our knowledge of tumor chemotherapy,” said Ray<br />

Vento, project officer for the ALA’s Asthma Clinical<br />

Research Center. “We are proud to have Dr. Meyerson<br />

among the American Lung Association’s awardees, and we<br />

hope that this support provides him the necessary assistance<br />

to further his innovative work.”<br />

<strong>The</strong> American Lung Association’s Nationwide Research<br />

Program, through which this ALA/LUNGevity Foundation<br />

Research Grant was awarded, is designed to support scientists<br />

whose studies may lead to prevention, relief, and cures for lung<br />

diseases. This funding will allow Meyerson to deepen his<br />

research into the identification of chromosomal alterations and<br />

mutations in adenocarcinoma.<br />

Meyerson believes this knowledge could provide clinicians<br />

with more effective means to pinpoint the disease using innovative<br />

therapies, thereby enabling targeted therapy in lung cancer.<br />

“<strong>The</strong> American Lung Association clearly shares our strong<br />

belief in the need to facilitate research into adenocarcinoma,”<br />

said Meyerson. “We greatly appreciate its support and generosity,<br />

and the opportunities this gift creates for us.”<br />

14 <strong>Impact</strong> <strong>Summer</strong> <strong>2005</strong>


Make your next gift online at www.dana-farber.org.<br />

Bette Winik extends her legacy of compassion<br />

Bette Winik dedicated her life, both<br />

personally and professionally, to<br />

helping others. She was particularly<br />

passionate about the plight of children, the<br />

homeless, and the struggles African-<br />

Americans often face. After her diagnosis<br />

with advanced ovarian cancer in 2003,<br />

Winik was treated at Dana-Farber and<br />

became committed to the cause of cancer<br />

prevention and research.<br />

Though she lost her battle with the disease<br />

at age 56, just one year after being<br />

diagnosed, her indomitable spirit lives on<br />

through numerous charitable bequests, including a<br />

$175,000 gift to Dana-Farber. This generous gift will support<br />

research into early detection of ovarian cancer.<br />

“Bette didn’t just throw money at the causes she cared<br />

about,” said Robert Brown, Winik’s friend of 12 years and<br />

executor of her estate. “She became intimately involved<br />

with each and every organization, and<br />

that spoke to her sincerity for these<br />

charities and their good works.”<br />

Winik was born in Harrison, N.Y.,<br />

and lived most of her adult life in<br />

Newton, Mass. A practicing attorney,<br />

she often represented children entangled<br />

in domestic relations disputes.<br />

Though she never had children of her<br />

own, she developed a deep love for<br />

children through her work.<br />

— Robert Brown Up until her death, Winik volunteered<br />

at Massachusetts Avenue Baptist<br />

Church’s Project Manna food ministry, attended gospel<br />

choir performances, and collected work by local artists<br />

with disabilities.<br />

“Bette was always involved with something,” recalled<br />

Brown. “We had a wonderful friendship, and I miss her<br />

very much.”<br />

“[Bette] became intimately<br />

involved with<br />

each and every organization,<br />

and that spoke<br />

to her sincerity for<br />

these charities and<br />

their good works.”<br />

Left to right: Pictured here in 2001 with<br />

friends Barbara and Sara Brown, Bette<br />

Winik created a legacy of compassion at<br />

Dana-Farber through a bequest gift supporting<br />

ovarian cancer research.<br />

Margie Plotka Levine dedicated her life to empowering others<br />

“Margie was<br />

interested in<br />

establishing her<br />

legacy to<br />

help others.”<br />

— Ralph Levine<br />

Margie Plotka Levine enjoyed<br />

being in touch with the<br />

world and healing her mind,<br />

body, and spirit at her house<br />

on Cape Cod.<br />

In 1989, 43-year-old Margie<br />

Plotka Levine was diagnosed with<br />

the deadliest form of lung cancer—malignant<br />

pleural mesothelioma.<br />

Given months to live, she<br />

fought back by adopting her own<br />

therapeutic program blending traditional<br />

and complementary medicine.<br />

Levine chronicled her recipe for life<br />

in her 2001 book, “Surviving<br />

Cancer” (Broadway Books).<br />

Levine put her affairs in order<br />

and prepared to die, but never lost<br />

hope. She made a provision for a<br />

$100,000 estate gift to support and<br />

name a treatment room in DFCI’s<br />

Leonard P. Zakim Center for<br />

Integrated <strong>The</strong>rapies, where she had<br />

received acupuncture, massage<br />

Established in 1990, the Dana-Farber Society honors the foresight<br />

and generosity of individuals who have included the Institute in<br />

their estate plans. Nearly 150 members and friends gathered at<br />

the Conference Center at Harvard Medical on June 22 for the<br />

Society’s 15th annual recognition dinner, hosted by Co-chairs<br />

Sandy and Dozier Gardner.<br />

At left, left to right: Lee Nadler, MD, senior vice president for<br />

experimental medicine at DFCI, spoke of the enduring partnership<br />

between the <strong>Jimmy</strong> <strong>Fund</strong> and the Boston Red Sox over his longstanding<br />

career with the Institute. Nadler then introduced his<br />

friend and former patient, Institute Trustee Larry Lucchino,<br />

therapy, and nutritional guidance.<br />

She died in March 2004, 14 years<br />

after her diagnosis.<br />

“Margie was interested in establishing<br />

her legacy to help others,”<br />

said Margie’s husband, Ralph Levine,<br />

who started a foundation to fulfill<br />

her dream of donating her book to<br />

cancer patients around the world.<br />

“She zeroed in on this room in the<br />

Zakim Center because it was off the<br />

beaten path and conveyed her goal<br />

of empowering others to heal.”<br />

Under the guidance of Zakim<br />

Center Director Cynthia Medeiros,<br />

LICSW, Levine’s gift will help the<br />

center maintain the frequency of its<br />

current services and provide resources<br />

for introducing new programs.<br />

“In many ways, Margie was like<br />

Lenny Zakim,” said Medeiros of the<br />

center’s namesake. “She, too, was a<br />

tremendous advocate for complementary<br />

therapies who focused her<br />

professional and personal energies on<br />

helping cancer patients gain access to<br />

these services.”<br />

Dana-Farber Society celebrates powerful partnerships<br />

Red Sox president and CEO, congratulating him on the<br />

team’s world championship and saying that together we<br />

will win the World Series against cancer.<br />

At right, left to right: Dana-Farber Society members<br />

Jacquelyn Farber and her husband, Institute Trustee<br />

Darwin Farber, trumpet the group’s success with Society<br />

Co-chairs Sandy Gardner and her husband, Institute<br />

Trustee Dozier Gardner.<br />

For more information about the Dana-Farber Society,<br />

visit www.dana-farber.org/society.<br />

<strong>Impact</strong> <strong>Summer</strong> <strong>2005</strong><br />

15


Calendar<br />

Get involved. Have fun. Beat cancer.<br />

d S E P T E M B E R d<br />

16<br />

From Fenway to the Runway<br />

Join the Red Sox wives at the shops and restaurants<br />

in <strong>The</strong> Heritage On <strong>The</strong> Garden in Boston for<br />

their fourth annual fashion show and luncheon to benefit<br />

DFCI’s Women’s Cancers Program and the Red Sox<br />

Foundation. For more information, call Alicia Gallo at<br />

(617) 632-3611 or visit www.jimmyfund.org/runway.<br />

18<br />

Boston Marathon ® <strong>Jimmy</strong> <strong>Fund</strong> Walk<br />

Be a Hero®. Join more than 6,000 walkers<br />

and travel along the official Boston<br />

Marathon® course in the 17th annual<br />

Walk, presented by Hyundai Motor<br />

America. Participate in the<br />

Hopkinton 26.2-Mile, the Wellesley<br />

13.1-Mile, or the Boston 3-Mile.<br />

Take the first step: register at<br />

www.<strong>Jimmy</strong><strong>Fund</strong>WalkRegistration.org or call the Walk<br />

office at (866) JFW-HERO.<br />

27<br />

Robert A. Kyle Lifetime<br />

Achievement Award<br />

Join us for a very special evening at the<br />

Harvard Club in Boston as the International<br />

Myeloma Foundation presents this annual<br />

award to Dana-Farber’s Kenneth Anderson,<br />

MD. For more information, contact<br />

Sarah Curtis at (617) 632-5091.<br />

<strong>Impact</strong><br />

<strong>Summer</strong> <strong>2005</strong><br />

www.jimmyfund.org and www.dana-farber.org<br />

Dana-Farber Cancer Institute<br />

Division of Development & <strong>The</strong> <strong>Jimmy</strong> <strong>Fund</strong><br />

10 Brookline Place West, 6th Floor<br />

Brookline, MA 02445-7226<br />

Address Service Requested<br />

<strong>The</strong> <strong>2005</strong> Susan F. Smith<br />

Inspiration Award was presented<br />

to Joyce Kulhawik, CBS4-TV arts<br />

and entertainment anchor<br />

and former Dana-<br />

Farber<br />

patient,<br />

during<br />

“Couture for<br />

Hope,” a<br />

fundraising event<br />

hosted by Neiman<br />

Marcus to support DFCI’s<br />

Women’s Cancers Program.<br />

Kulhawik, pictured wearing a<br />

Carolina Herrera gown, is a<br />

three-time cancer survivor.<br />

Thanking those who make a difference.<br />

Non-profit Org.<br />

U.S. Postage<br />

PAID<br />

Dana-Farber<br />

e O C T O B E R e<br />

2<br />

Jeni <strong>Fund</strong> Off-Road Duathlon<br />

Help beat lung cancer by participating in this<br />

third annual athletic event—a sequential 2-mile trail<br />

run, 9-mile mountain bike, and 2-mile trail run—at<br />

Wompatuck State Park in Hingham, Mass. For more<br />

information, contact Alicia Gallo at (617) 632-3611 or<br />

visit www.jenifund.org.<br />

9<br />

B.A.A. Half Marathon ®<br />

Be a part of Dana-Farber’s winning team in the<br />

annual B.A.A. Half Marathon® as it races through Boston’s<br />

Back Bay Fens toward the ultimate finish line: a world<br />

without cancer. For more information, call the Marathon<br />

and Running Programs hotline at (800) 551-7036 or visit<br />

www.jimmyfund.org/halfmarathon.<br />

14 –15<br />

An Evening with<br />

Champions<br />

Don’t miss this world-class figure skating exhibition,<br />

hosted by Eliot House of Harvard<br />

University. This inspirational event has raised more<br />

than $2.2 million for the <strong>Jimmy</strong> <strong>Fund</strong> since 1970.<br />

For more information, call the EWC office at (617)<br />

493-8172 or visit www.aneveningwithchampions.org.<br />

15<br />

Jefferson Starship Galactic<br />

Reunion Concert<br />

Groove to the music performed live by original<br />

members of Jefferson Airplane and Jefferson Starship<br />

at the Berklee Performance Center in Boston.<br />

VIP tickets include meeting the band, a live CD,<br />

and preferred seating. For more information, visit<br />

www.jimmyfund.org/eve/event/jefferson-starship, or contact<br />

Caitlin Fay at (617) 632-4215.<br />

16<br />

Holliston Walks for Breast Cancer<br />

Take a stroll through scenic Holliston, Mass., as<br />

part of this third annual event to benefit breast cancer<br />

research and patient care at Dana-Farber. For more<br />

information, contact Jayne Jones at (508) 893-9927 or<br />

e-mail tjones3924@aol.com.<br />

21–22<br />

Oldies but Goodies<br />

Musical Review<br />

Help fight cancer while listening to local musicians<br />

performing current hits and classic songs dating back<br />

to the 1940s. This event will be held at the First<br />

Methodist Church in Pittsfield, Mass., and tickets are<br />

$10. For more information, contact Cathy Soldo at<br />

(413) 442-3647.<br />

26<br />

QVC presents FFANY Shoes on Sale<br />

Choose among thousands of designer and brandname<br />

shoes offered at half the suggested retail price.<br />

<strong>The</strong> 12th annual Shoes on Sale® event, presented<br />

by QVC and the Fashion Footwear Association of<br />

New York, benefits breast cancer research and<br />

education at DFCI and other national centers.<br />

For more information, contact Sarah<br />

Curtis at (617) 632-5091.<br />

28– 29<br />

Saks ”Key To <strong>The</strong> Cure”<br />

Join the Friends of Dana-<br />

Farber Cancer Institute and Saks<br />

Fifth Avenue for an Oct. 28<br />

luncheon—catered by Boston’s<br />

top restaurants—to benefit<br />

DFCI’s Women’s Cancers Program<br />

(WCP). As part of its “Key To <strong>The</strong><br />

Cure” initiative, Saks will donate 5 percent of all clothing<br />

sales on Oct. 28 – 29 to the WCP. For more information,<br />

contact the Friends office at (617) 632-3021.<br />

wNOVEMBER/DECEMBERw<br />

November<br />

30<br />

Cheers for Children<br />

Celebrate the holidays with fabulous food and<br />

great auction items at the Hampshire House’s Bull &<br />

Finch Pub in Boston, the inspiration for the hit TV<br />

show “Cheers.” For more information, contact Caitlin<br />

Fay at (617) 632-4215.<br />

November & December<br />

Robert’s Snow for Cancer’s Cure<br />

Support Dana-Farber’s lifesaving mission by<br />

purchasing one-of-a-kind designs from<br />

your favorite children’s book illustrators. Chris<br />

Van Allsburg (“<strong>The</strong> Polar Express”), Tomie<br />

dePaola (“Strega Nona”), Barbara Lehman<br />

(“<strong>The</strong> Red Book”), and others will create original<br />

snowflake-shaped works of art and auction them<br />

off to support sarcoma research at DFCI. For more<br />

information, visit www.robertssnow.com.<br />

November & December<br />

Dan Murphy Christmas Tree Sale<br />

Buy a wreath or Christmas tree as part of this 35-year<br />

holiday tradition to benefit the <strong>Jimmy</strong> <strong>Fund</strong>. Trees cost<br />

$15–40 and can be chosen at the Murphy home, located<br />

at 310 Highland Ave. in Randolph, Mass. For more<br />

information, call Dan Murphy at (781) 963-5675.<br />

December<br />

7<br />

CIBC Miracle Day<br />

Make your individual or institutional stock trades<br />

through CIBC World Markets, a full-service investment<br />

bank, and designate the <strong>Jimmy</strong> <strong>Fund</strong> as your charity of<br />

choice. Dana-Farber will receive all of the day’s commissions<br />

that accrue from these trades. For more information,<br />

contact Priya McCue at (617) 632-4906 or visit<br />

www.jimmyfund.org/CIBC.<br />

For more information on all <strong>Jimmy</strong> <strong>Fund</strong> and Dana-Farber events, go to www.jimmyfund.org or www.dana-farber.org.

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