Impact Summer 2005 - The Jimmy Fund
Impact Summer 2005 - The Jimmy Fund
Impact Summer 2005 - The Jimmy Fund
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Volume 8 • Issue 3<br />
<strong>Impact</strong><br />
Thanking those who make a difference.<br />
<strong>Summer</strong> <strong>2005</strong><br />
www.jimmyfund.org and www.dana-farber.org<br />
Stop & Shop Triple Winner Game marks<br />
15 years of fighting pediatric cancer<br />
3<br />
Faithful<br />
Family<br />
9<br />
Spirited<br />
Sailors<br />
In <strong>2005</strong>, Stop & Shop Supermarket Company<br />
was awarded the prestigious Silver Halo Award<br />
from the Cause Marketing Forum for its<br />
continuing support of the <strong>Jimmy</strong> <strong>Fund</strong> through<br />
the Triple Winner Game. Stop & Shop President<br />
and CEO Marc Smith is pictured above.<br />
Over the years, Stop & Shop<br />
Supermarket Company has served<br />
as a steadfast ally in the <strong>Jimmy</strong><br />
<strong>Fund</strong>’s battle against pediatric brain<br />
tumors, resulting in the founding of the<br />
Stop & Shop Family Pediatric Brain Tumor Clinic at Dana-Farber in<br />
1997. <strong>The</strong> center’s establishment and subsequent growth could not have<br />
been possible without the retail grocery chain’s support through its Triple<br />
Winner Game. <strong>The</strong> popular program celebrated its 15th anniversary this<br />
year and observed the occasion by raising $4 million, bringing its overall<br />
fundraising total to a victorious $33 million.<br />
“This milestone could not have been reached without the unwavering<br />
commitment to pediatric brain cancer cures made by our customers,<br />
employees, distributors, and suppliers,” said Marc Smith, president and<br />
CEO of Stop & Shop. “<strong>The</strong>ir dedication to the Triple Winner Game<br />
program has allowed Dana-Farber to offer new treatments and make<br />
medical advances that were never dreamed possible 15 years ago.”<br />
<strong>The</strong> Triple Winner Game, which kicked off on April 17 and ran until<br />
July, allowed Stop & Shop’s valued customers throughout the Northeast<br />
to contribute $1 to benefit cancer care and research. In return, they<br />
10<br />
Committed<br />
Cyclists<br />
11<br />
Elegant<br />
Event<br />
15<br />
Lasting<br />
Legacy<br />
continued on page 8<br />
Embarking on the future: PMC riders pedal toward cures<br />
When he founded the<br />
country’s first fundraising<br />
bike-a-thon in 1980,<br />
Billy Starr was not aware of the<br />
impact it would have on the lives<br />
of those facing cancer. “Almost<br />
immediately after the first Pan-<br />
Massachusetts Challenge, I realized<br />
I had tapped into something more<br />
powerful than the money we had<br />
raised,” recalled Starr.<br />
Now in its 26th year, the Pan-<br />
Massachusetts Challenge (PMC) and<br />
its devoted riders maintain an incredible<br />
spirit of inspiration, determination,<br />
and energy as they take on the<br />
challenging course to fight cancer.<br />
In <strong>2005</strong>, Starr expects the event to<br />
raise $21 million and bring its total<br />
contribution to the <strong>Jimmy</strong> <strong>Fund</strong> to<br />
more than $143 million. <strong>The</strong> PMC<br />
has grown to be the nation’s most<br />
successful athletic fundraising event,<br />
leading the way in efficiency by giving<br />
97 percent of all money raised<br />
to support the lifesaving work of<br />
Dana-Farber.<br />
“<strong>The</strong> PMC has made what we do at<br />
Dana-Farber possible,” said Institute<br />
President Edward J. Benz Jr., MD.<br />
“When they write the history of how<br />
cancer was conquered, the PMC will be<br />
in chapter one.”<br />
Going the distance<br />
On Aug. 6 and 7, more than 4,000<br />
cyclists hailing from 35 states and six<br />
countries rode across the commonwealth.<br />
Cancer survivors, current<br />
patients, and supporters pedaled<br />
one of six taxing courses between<br />
Sturbridge and Provincetown, Mass.<br />
Nearly 2,200 volunteers helped make<br />
the event a reality and were instrumental<br />
to the weekend’s success. As<br />
presenting co-sponsors, the Boston<br />
Red Sox and Overstock.com made the<br />
event possible, while 200 other generous<br />
companies provided in-kind and<br />
financial contributions.<br />
Below, left to right:<br />
<strong>The</strong> PMC draws its<br />
share of celebrities,<br />
including Team 9<br />
members and Red<br />
Sox wives Kathryn<br />
Nixon, Dawn Timlin,<br />
Nixon’s friend<br />
Bassima Connelly,<br />
and Shonda Schilling.<br />
Above: Sox President and CEO<br />
Larry Lucchino, a two-time<br />
cancer survivor treated at<br />
Dana-Farber, personally thanks<br />
the PMC riders who have<br />
helped raise a combined $143<br />
million for the Institute over<br />
the last 26 years.<br />
continued on page 10<br />
Left: Massachusetts Sen. John Kerry,<br />
a cancer survivor, shows his commitment<br />
to finding cures by joining<br />
more than 4,000 fellow cyclists.<br />
Right: A sea of riders makes a mad<br />
dash from the starting line in<br />
Sturbridge, Mass., anticipating the<br />
192-mile journey that lies ahead.
Lively summer events season scores<br />
a home run for Dana-Farber<br />
Dear Friends,<br />
<strong>The</strong> <strong>Jimmy</strong> <strong>Fund</strong><br />
is extremely thankful<br />
to boast a vibrant<br />
calendar of events<br />
that reflects the<br />
community’s<br />
extraordinary dedication<br />
to Dana-<br />
Farber’s fight against<br />
cancer. In <strong>2005</strong> alone, thousands of<br />
volunteers will rally for the cause by<br />
initiating more than 500 fun-filled<br />
fundraising events.<br />
This <strong>Impact</strong> spotlights just a few<br />
of the festivities that took place during<br />
our busiest summer season to<br />
date. In June, we launched the<br />
<strong>Jimmy</strong> <strong>Fund</strong> Regatta, which attracted<br />
hundreds of competitive sailors. <strong>The</strong><br />
inaugural event set sail in Newport,<br />
R.I., and sped past its $100,000<br />
fundraising goal. In July, Institute<br />
Trustee George Cloutier opened his<br />
Nantucket home for the second<br />
annual Boogie on Low Beach “funraiser,”<br />
which garnered more than<br />
$500,000 through ticket<br />
sales and a fabulous<br />
auction. And in August,<br />
avid baseball fans took<br />
to the field for the 14th<br />
annual John Hancock<br />
Fantasy Day at Fenway<br />
Park. Participants<br />
helped raise more than<br />
$620,000 as they lived<br />
their dreams and played ball like<br />
their favorite Boston Red Sox heroes.<br />
You’ll also read about the more<br />
than 4,000 Pan-Massachusetts<br />
Challenge (PMC) cyclists and 2,200<br />
volunteers who helped raise millions<br />
for Dana-Farber during their August<br />
odyssey across the commonwealth.<br />
Under the leadership of PMC<br />
Founder and Executive Director Billy<br />
Starr, the nation’s original fundraising<br />
bike-a-thon has raised an incredible<br />
$143 million for DFCI over its 26-<br />
year history.<br />
Finally, thousands of men and<br />
women hit the fairways for the first<br />
half of the <strong>2005</strong> <strong>Jimmy</strong> <strong>Fund</strong> Golf<br />
season. By mid-July, 78 of the 150<br />
total tournaments had already raised<br />
$2.5 million toward the program’s<br />
$5.2 million annual goal. Integral to<br />
this success were new events—such as<br />
the one sponsored by Sea View<br />
Technologies in Exter, N.H.—as well<br />
as more mature tournaments, including<br />
the 26th Annual <strong>Jimmy</strong> <strong>Fund</strong><br />
Golf Tournament/Jeffrey Vinick<br />
Memorial, which was played on five<br />
courses this year.<br />
As you can see, it has been a truly<br />
exciting summer. Thank you to each<br />
and every one of our event participants,<br />
volunteers, sponsors, and<br />
supporters who have given so generously<br />
of their time and resources.<br />
Collectively, the funds raised through<br />
these events directly support the<br />
search for cancer cures. We couldn’t<br />
do it without you!<br />
Susan S. Paresky<br />
Senior Vice President for Development<br />
Fantasy Day bats in big fundraising<br />
for the <strong>Jimmy</strong> <strong>Fund</strong><br />
<strong>The</strong> excitement surrounding the legendary 2004<br />
Boston Red Sox World Series victory was still going<br />
strong this summer as fans lined up for a chance to<br />
participate in the 14th annual John Hancock Fantasy Day at<br />
Fenway Park. At Fantasy Day, people made gifts to<br />
the <strong>Jimmy</strong> <strong>Fund</strong> for the chance to play ball like<br />
their Red Sox heroes. Held on Aug. 6, the baseball<br />
extravaganza earned more than $620,000 to<br />
help Dana-Farber strike out cancer.<br />
For many, playing in historic Fenway was a major<br />
league dream. Fans were able to hit one against the<br />
famed left-field wall, the Green Monster, or play in the outfield<br />
to snag some fly balls and a piece of baseball glory.<br />
From early in the morning until after sunset, these amateurs<br />
became pros, with memories courtesy of the generosity of<br />
presenting sponsor John Hancock Financial Services.<br />
“As a dedicated supporter of both the <strong>Jimmy</strong> <strong>Fund</strong> and<br />
Major League Baseball, we see Fantasy Day as a great opportunity<br />
for our company to demonstrate its deep commitment<br />
to improving the lives<br />
of cancer patients<br />
everywhere by participating<br />
in<br />
America’s favorite<br />
pastime,” said Robert<br />
Friedman, assistant<br />
vice president of<br />
This novice baseball player is poised to<br />
hit one against Fenway Park’s famed<br />
left-field wall, the Green Monster.<br />
sports and event<br />
marketing at<br />
John Hancock.<br />
THE<br />
T O<br />
B E<br />
N E F<br />
I T<br />
JIMMY FUND<br />
Robert Russo (left), and his father, Bob, both devout New<br />
York Yankees fans, demonstrated an even greater allegiance<br />
to the <strong>Jimmy</strong> <strong>Fund</strong> by participating in the Boston<br />
Red Sox-themed Fantasy Day event.<br />
Rivals come together for a great cause<br />
For most New York Yankees fans, the idea of playing<br />
ball at Fenway while wearing Sox uniforms would be sacrilegious.<br />
However at this year’s Fantasy Day, Robert Russo<br />
of Astoria, N.Y., and his friends and family hit the field,<br />
proving that even the greatest rivalry in sports takes a back<br />
seat when it comes to fighting cancer. Diagnosed with sarcoma<br />
in 1999, Russo came to Dana-Farber to combat this<br />
difficult-to-treat disease. With his cancer now stabilized,<br />
he saw Fantasy Day as a great way to give back to the<br />
place that continues to give him a second chance at life.<br />
“If it weren’t for Dana-Farber, I would not be here to<br />
have the opportunity to play ball at all,” said Russo.<br />
“Though it isn’t pleasant to have to wear the Red Sox<br />
jersey, it’s definitely worth it knowing that the money<br />
raised will help others.”<br />
<strong>Impact</strong><br />
<strong>Summer</strong> <strong>2005</strong> • Volume 8 • Issue 3<br />
This issue covers gifts received and finalized<br />
through the spring and summer of <strong>2005</strong>.<br />
<strong>Impact</strong>, a newsletter of Dana-Farber Cancer<br />
Institute and the <strong>Jimmy</strong> <strong>Fund</strong>, is published by the<br />
Department of Communications in collaboration<br />
with the Division of Development for friends and<br />
supporters of Dana-Farber and the <strong>Jimmy</strong> <strong>Fund</strong>.<br />
President, Dana-Farber Cancer Institute<br />
Edward J. Benz Jr., MD<br />
Chief of Staff<br />
Stephen E. Sallan, MD<br />
Chief Medical Officer<br />
Lawrence Shulman, MD<br />
Chief Scientific Officer<br />
Barrett Rollins, MD, PhD<br />
Chair of Medical Oncology<br />
James Griffin, MD<br />
Chair of Pediatric Oncology<br />
Stuart H. Orkin, MD<br />
Senior Vice President for Development<br />
Susan S. Paresky<br />
Chairman of the <strong>Jimmy</strong> <strong>Fund</strong><br />
Michael J. Andrews<br />
Senior Vice President for Communications<br />
Steven R. Singer<br />
<strong>Impact</strong> Editors<br />
Laura DeCoste, Dawn Stapleton<br />
Contributors<br />
Alan Caplan, Michael Elvin, David Ferreira,<br />
Brian Geer, Bob Israel, Sara Johnson,<br />
Kristin Lacey, Susan Rice, Beth Rossi,<br />
Lora Sharpe, Tom Ulrich, Coral Vogel<br />
Art Director<br />
John DiGianni<br />
Designer<br />
Irina Zlobina<br />
Production Coordinator<br />
Jeff Cleary<br />
Photographers<br />
Lucien Capehart, Lisa Cohen, Karen Cummings,<br />
John Deputy, Roger Farrington, Dan Furness,<br />
Steve Gilbert, Shawn Henry, Justin A. Knight,<br />
Matthew McKee, Mark Ostow, Philip Porcella,<br />
Jack Slomovitz Photographers,<br />
Coral Vogel, Laura Wulf<br />
Requests for copies of <strong>Impact</strong> may be sent to:<br />
DFCI Development Office<br />
10 Brookline Place West, 6th Floor<br />
Brookline, MA 02445-7226<br />
(617) 632-3019<br />
or download an issue at<br />
www.dana-farber.org/impact<br />
Since its founding in 1947 by the late Sidney<br />
Farber, MD, Dana-Farber Cancer Institute has<br />
been committed to a single mission: providing<br />
cancer patients with the best treatments available<br />
today, while developing the cures for tomorrow.<br />
Its researchers are also making strides against<br />
illnesses as devastating as AIDS and as ordinary<br />
as the common cold.<br />
A principal teaching affiliate of Harvard Medical<br />
School, the Institute is a founding member of<br />
the Dana-Farber/Harvard Cancer Center, one of<br />
39 comprehensive cancer centers designated by<br />
the National Cancer Institute. Dana-Farber is<br />
also one of 20 federally designated Centers for<br />
AIDS Research in the United States. In addition<br />
to providing advanced training for cancer physicians<br />
and researchers, the Institute conducts<br />
community-based programs in cancer control<br />
and detection throughout New England.<br />
Much of the work of Dana-Farber is made<br />
possible by the generous supporters of the<br />
<strong>Jimmy</strong> <strong>Fund</strong>, the fundraising organization<br />
named for one of Dr. Farber’s young patients.<br />
Founded in 1948, the <strong>Jimmy</strong> <strong>Fund</strong> is an official<br />
charity of the Boston Red Sox, the Massachusetts<br />
Chiefs of Police Association, the annual Pan-<br />
Massachusetts Challenge bike-a-thon, and the<br />
Variety Children’s Charity of New England.<br />
Each year, thousands of volunteers and donors<br />
organize and participate in <strong>Jimmy</strong> <strong>Fund</strong> events.<br />
2 <strong>Impact</strong> <strong>Summer</strong> <strong>2005</strong>
Giving is easy when you visit us online at www.dana-farber.org.<br />
Quick family honors second<br />
clinical researcher with<br />
senior investigatorship<br />
Aesclepian Society celebrates<br />
extraordinary generosity<br />
Named for Aesclepius, the<br />
Roman god of medicine, the<br />
Aesclepian Society recognizes<br />
the most loyal benefactors of<br />
Dana-Farber and the <strong>Jimmy</strong><br />
<strong>Fund</strong>. Through one-time commitments<br />
of $1 million or more,<br />
these generous donors have<br />
helped to profoundly shape<br />
the Institute’s future.<br />
Fifteen new individuals,<br />
families, and organizations were<br />
inducted into this intimate circle<br />
on May 4, joining the 75 members<br />
welcomed at the society’s<br />
inaugural gathering in 2003.<br />
Held at the Ritz-Carlton Boston,<br />
the Aesclepian Society dinner<br />
featured personal messages of<br />
thanks from Institute President<br />
Edward J. Benz Jr., MD, and<br />
Board of Trustees Chairman<br />
Gary Countryman.<br />
A 27-year cancer survivor, Institute<br />
Trustee Barbara Sadowsky<br />
shared her inspirational story<br />
and said she was living proof of<br />
the amazing care Dana-Farber<br />
provides. Keynote speaker and<br />
Harvard University President<br />
Lawrence <strong>Summer</strong>s, who is also<br />
a cancer survivor, discussed the<br />
powerful convergence of science<br />
and medicine at Harvard and<br />
throughout Boston, as well as<br />
Dana-Farber’s leadership role in<br />
this area.<br />
Above: President Benz (left)<br />
welcomed Board Chairman Gary<br />
Countryman into the Aesclepian<br />
Society and thanked him for his<br />
long-standing support.<br />
Twice, the Quick family has become intimately connected with Dana-<br />
Farber through the treatment of a loved one. And both times, they have<br />
joined together to honor the heroic care and groundbreaking research of<br />
an Institute physician.<br />
In 1999, DFCI Chief of Staff Stephen E. Sallan, MD, a renowned authority<br />
on acute lymphoblastic leukemia (ALL), was recognized with the Quick Family<br />
Senior Investigatorship in Pediatric Oncology for his successful treatment of<br />
Institute Trustee Nancy (Quick) Gibson’s son.<br />
<strong>The</strong> Quicks—mother Regina; sons Christopher, Leslie III, Peter, and Thomas;<br />
and daughters Mary Pedersen, Patricia DeVisscher, and Nancy Gibson—have<br />
now extended a similar honor to George Demetri, MD, by establishing the<br />
Quick Family Senior Investigatorship in Medical Oncology. Demetri, director of<br />
the Center for Sarcoma and Bone Oncology (CSBO), cared for late Institute<br />
Trustee and family patriarch Leslie Jr. during his battle with sarcoma. Demetri’s<br />
clinical efforts and pioneering work on novel therapeutics touched the entire<br />
family, prompting them to create the new investigatorship.<br />
“George has done and continues to do great work,” said Leslie III, “and this<br />
gift is a small acknowledgment of his success. <strong>The</strong>re are cures for all cancers out<br />
there and we, as a family, believe that Dana-Farber’s position as a leader in collaborative<br />
science will bring those cures to reality.”<br />
A paradigm for all cancers<br />
This new academic chair, endowed with a $2.5 million gift from the family,<br />
will bolster efforts by Demetri, a world expert on the biology and treatment of<br />
sarcomas, and his team in<br />
the CSBO. Together, they<br />
are working to unlock the<br />
molecular secrets of these<br />
relatively rare tumors and<br />
transform the knowledge<br />
gained into new therapeutic<br />
strategies. For example, the<br />
“<strong>The</strong>re are cures for all cancers out<br />
there and we, as a family, believe<br />
that Dana-Farber’s position as a<br />
leader in collaborative science<br />
will bring those cures to reality.”<br />
— Leslie Quick III<br />
team broke new ground with the use of “targeted” drugs like Gleevec ® and<br />
SU11248 (SUTENT) to treat the previously untreatable gastrointestinal stromal<br />
tumor (GIST).<br />
“<strong>The</strong> work of our entire team here at Dana-Farber, together with our collaborators<br />
worldwide, has made it possible for patients with GIST and other sarcomas<br />
to live longer than ever before,” Demetri said. “With the generous and<br />
visionary support of the Quick Investigatorship, we will continue to expand our<br />
work in this unique, team-focused environment.”<br />
<strong>The</strong> DFCI team’s efforts have also made sarcomas valuable models for understanding<br />
the intricacies of numerous cancers.<br />
“Sarcomas provide important clues to the causes and treatments of many cancers,<br />
from solid tumors to blood cancers,” explained Demetri. “By studying<br />
sarcomas clinically, we are gaining insights critical to cancer research in general.<br />
Simultaneously, we are developing new drugs for sarcoma patients who have a<br />
genuine unmet medical need.”<br />
Demetri continued, “I am deeply grateful to the entire Quick family for its<br />
ongoing support and for the recognition that the work here at Dana-Farber, built<br />
upon past successes, present science, and future applications, will ultimately help<br />
overcome the challenges<br />
of cancer.”<br />
<strong>The</strong> Quick family, including (above, left to right)<br />
Regina Quick, Thomas Quick, and Institute Trustee<br />
Nancy Gibson, has banded together to honor DFCI’s<br />
George Demetri, MD, (inset) with the Quick Family<br />
Senior Investigatorship in Medical Oncology.<br />
<strong>Impact</strong> <strong>Summer</strong> <strong>2005</strong> 3
Get involved, have fun, and beat cancer at www.jimmyfund.org.<br />
Golfers take a swing against cancer<br />
This summer on New England courses and beyond, golfers were teeing<br />
up for the <strong>Jimmy</strong> <strong>Fund</strong>. By mid-July, 78 of the 150 total tournaments<br />
in <strong>2005</strong> had already raised an amazing $2.5 million toward <strong>Jimmy</strong> <strong>Fund</strong><br />
Golf’s $5.2 million annual goal. Participants enjoyed time on the fairways while<br />
raising critical funds for Dana-Farber.<br />
Tournaments honored friends’, family members’, and colleagues’ battles<br />
with cancer. <strong>The</strong> Mark Ungerer Driving for the Cure Memorial Golf<br />
Tournament, for instance, paid tribute to the life of a beloved friend to many.<br />
Ungerer bravely faced cancer and was known for his generosity in donating his<br />
time to numerous community causes. Held July 10–11 at <strong>The</strong> International in<br />
Bolton, Mass., the tournament raised more than $440,000.<br />
the 26th Annual <strong>Jimmy</strong> <strong>Fund</strong> Golf<br />
Tournament/Jeffrey Vinick Memorial.<br />
This popular event celebrated its<br />
greatest success to date by raising a hefty<br />
$415,000 on June 20, bringing its cumulative<br />
fundraising tally to more than $4.5<br />
million since 1980.<br />
<strong>The</strong> tournament’s celebration dinner was<br />
held at the Basketball Hall of Fame in<br />
Springfield, Mass., and brought together<br />
golfers from each of the five different<br />
courses where the tournament was played.<br />
Among the guests was this year’s Sadowsky<br />
At the <strong>Jimmy</strong> <strong>Fund</strong> Players<br />
Tournament, co-organizer Jim<br />
Dow (left) and Jim Sims plan their<br />
strategy from the tee.<br />
Visionary Award winner, Police Chief Donald Maia of Amherst, Mass. <strong>The</strong><br />
award is named for Institute Trustees Barbara and Jim Sadowsky and given to<br />
those who make an extraordinary commitment to an event that provides<br />
annual support to the <strong>Jimmy</strong> <strong>Fund</strong> and the mission of DFCI. Chief Maia<br />
joined forces with the <strong>Jimmy</strong> <strong>Fund</strong> in 1961, serving as the creator and first<br />
president of the <strong>Jimmy</strong> <strong>Fund</strong> Council of Western Massachusetts. He inspired<br />
a legacy of grassroots fundraising.<br />
Left to right: Bob Kletjian, vice chairman at UNICCO; Stan Oldfield, retired executive<br />
from TJX; Rick Kletjian, vice chairman at UNICCO; and <strong>Jimmy</strong> <strong>Fund</strong> Chairman Mike<br />
Andrews wrap-up 18 holes at the <strong>Jimmy</strong> <strong>Fund</strong>/UNICCO Golf & Tennis Classic.<br />
“When it came time to give, Mark Ungerer would identify a gap and ask<br />
‘How can I help to fill it?’” said Jim Coghlin, co-chairman of the Ungerer<br />
Tournament. “Our golf tournament to benefit the great work at Dana-Farber is<br />
our way, as a community of friends, to honor the memory of a great man and<br />
to have a heck of a good time in the process.”<br />
Coghlin added, “Honoring those who have touched our lives brings out the<br />
best in us. Honoring those who have touched the lives of countless people in need<br />
brings out the best in a community.”<br />
Another tournament that made a great impact in the fight against cancer was<br />
<strong>The</strong> commitment of many<br />
Numerous other <strong>Jimmy</strong> <strong>Fund</strong> Golf tournaments also made a profound<br />
commitment to fight cancer and each raised $100,000 or more. <strong>The</strong>y include:<br />
• <strong>The</strong> Mutual <strong>Fund</strong>s Against Cancer Golf Classic, raising more than<br />
$200,000.<br />
• <strong>The</strong> <strong>Jimmy</strong> <strong>Fund</strong>/UNICCO Golf & Tennis Classic, raising $140,000.<br />
• <strong>Jimmy</strong> <strong>Fund</strong> Players Tournament, raising more than $130,000.<br />
• Kristin’s <strong>Fund</strong> 5th Annual Golf Tournament, raising $105,000.<br />
• 13th Annual David B. Perini, Jr. Memorial Golf Tournament, raising<br />
more than $100,000.<br />
<strong>Jimmy</strong> <strong>Fund</strong> Golf is well on its way to completing another successful season,<br />
bringing golf lovers together on the green to make a difference in the<br />
lives of cancer patients around the world.<br />
Left to right: Bonnie Hamill, Jessie Hoffman, Institute Trustees Jim and Barbara<br />
Sadowsky, and Jackie Hoffman celebrate at the Basketball Hall of Fame following<br />
the 26th Annual <strong>Jimmy</strong> <strong>Fund</strong> Golf Tournament/Jeffrey Vinick Memorial.<br />
Epsteins champion Women’s Cancers Program investigator<br />
True to its name, Champion Exposition Services has<br />
designated its fourth major gift in as many years to<br />
help Dana-Farber win the battle against women’s cancers.<br />
This year’s Champion Exposition Services’ Investigator<br />
Award—a $100,000 gift made possible by<br />
Mark and Eileen Epstein—provides DFCI’s<br />
Akila Viswanathan, MD, MPH, with the<br />
funding necessary to explore lifestyle risk<br />
factors for endometrial cancer, which affects<br />
the lining of the uterus.<br />
“<strong>The</strong> work being done today at Dana-<br />
Farber continues a long history of extraordinary progress,”<br />
said Mark Epstein, Champion’s founder, president, and<br />
CEO. “We believe that the Women’s Cancers Program is a<br />
perfect example of that development.”<br />
Through their Middleboro, Mass.-based company, which<br />
specializes in organizing tradeshows and events, the<br />
Epsteins have begun a tradition by generously supporting<br />
researchers in Dana-Farber’s Women’s Cancers Program<br />
year after year. <strong>The</strong>ir most recent gift will allow<br />
Viswanathan to delve into the effects of smoking, exercise,<br />
and aspirin use on endometrial cancer.<br />
“It is an honor to receive this prestigious award,” said<br />
Viswanathan. “<strong>The</strong> support provided by Champion<br />
Exposition Services and the Epsteins will be invaluable to<br />
my research into endometrial cancer.”<br />
J. Dirk Iglehart, MD, director of DFCI’s Women’s<br />
Cancers Program, also recognizes the far-reaching importance<br />
of the Champion Exposition Services’ Investigator<br />
Award. “Ultimately, Dr. Viswanathan’s research will contribute<br />
significantly to advancing knowledge of all<br />
women’s cancers,” he said.<br />
Thanks to the latest gift from Champion<br />
Exposition Services, Dana-Farber’s Akila<br />
Viswanathan, MD, MPH, is exploring lifestyle<br />
risk factors for endometrial cancer.<br />
4 <strong>Impact</strong> <strong>Summer</strong> <strong>2005</strong>
Dyson Foundation gift supports breast cancer research<br />
Eric Winer, MD, is researching new treatment<br />
approaches for women with basal-like cancers whose<br />
tumors have been resistant to hormonal therapy.<br />
Research into an aggressive<br />
form of breast cancer that<br />
claimed the life of Anne<br />
Dyson, MD, in 2000 will be supported<br />
by a new gift of $750,000<br />
by the New York-based Dyson<br />
Foundation. Established in 1957<br />
by Anne’s parents, Charles and<br />
Margaret, the foundation’s newest<br />
gift also gives momentum to Dana-<br />
Farber’s planned comprehensive<br />
capital campaign. <strong>The</strong> cutting-edge<br />
investigations will be led by Eric<br />
Winer, MD, director of DFCI’s<br />
Breast Oncology Center.<br />
Dyson worked as a pediatrician<br />
and was well-connected to Dana-<br />
Farber, having served as a trustee<br />
before becoming a patient of<br />
Winer’s. “Annie was bright, creative,<br />
enormously empathetic, and very<br />
funny,” said Winer. “I had a great<br />
deal of admiration for her.”<br />
Winer and his colleagues will use<br />
this gift to focus on basal-like, or triple negative, cancers,<br />
which account for 10–15 percent of all breast tumors. <strong>The</strong>se<br />
forms of breast cancer are characterized by tumors that are<br />
resistant to hormonal therapy.<br />
“New treatment approaches are desperately needed for<br />
women who have basal-like cancers,” Winer explained.<br />
“With the Dyson Foundation’s support, we will be able to<br />
extend our research in this area.”<br />
Stalwart advocate<br />
<strong>The</strong> Dyson Foundation has been a stalwart advocate of<br />
research at DFCI. Now run by Anne’s brother, Robert<br />
Dyson, the foundation also established a chair in pediatrics<br />
at the Institute in memory of their mother, Margaret M.<br />
Dyson, who died of ovarian cancer.<br />
This David G. Nathan Chair in Pediatrics, named after<br />
DFCI President Emeritus David G. Nathan, MD, and now<br />
held by Stuart Orkin, MD, chair of Pediatric Oncology, was<br />
followed by the 2001 establishment of the Anne E. Dyson<br />
Chair in Women’s Cancers, now held by J. Dirk Iglehart,<br />
MD, director of Dana-Farber’s Women’s Cancers Program.<br />
“We are honored to be able to help Dr. Winer in the<br />
thoughtful approach he is bringing to the future of breast<br />
cancer research,” said Robert Dyson.<br />
Nantucket “fun-raiser” garners<br />
$500,000-plus for Dana-Farber<br />
Fun and fundraising<br />
went hand-in-hand<br />
at the second annual<br />
“Boogie on Low Beach”<br />
event hosted by Institute<br />
Trustee George Cloutier<br />
in Nantucket, Mass. <strong>The</strong><br />
event raised more than<br />
$500,000 for Dana-Farber’s<br />
lifesaving mission, thanks to<br />
the generosity of Cloutier<br />
and his guests.<br />
“I’m thrilled that this<br />
event has been so successful<br />
so quickly,” said Cloutier.<br />
“I can’t thank my Nantucket<br />
neighbors and our terrific<br />
sponsors enough.”<br />
Some 650 guests dined<br />
Institute Trustee George Cloutier (left) welcomed<br />
nearly 650 guests at his fun-filled fete<br />
benefiting Dana-Farber. Cloutier's guest of<br />
honor was Boston Red Sox President and CEO<br />
Larry Lucchino (right).<br />
and danced under a tent at Cloutier’s Siasconset home on the night of<br />
July 22. Intercontinental Real Estate Corporation, a real estate investment<br />
manager and developer, was the event’s principal underwriter.<br />
WCVB-TV’s Natalie Jacobson served as master of ceremonies. Dozens<br />
of local and Boston businesses contributed fabulous prizes to both live<br />
and silent auctions. Items up for bid included lunch for three with<br />
Jack Welch at Boston restaurant No. 9 Park; a five-night stay valued at<br />
$15,000 donated by the luxury destination club Dream Catcher; a Palm<br />
Beach, Fla., weekend with a stay at a waterfront mansion; a round of golf<br />
and lunch at Mar-a-Lago; and a private dinner party prepared by celebrity<br />
chef Todd English.<br />
<strong>The</strong> event honored Larry Lucchino, president and CEO of the Boston<br />
Red Sox and a two-time cancer survivor treated at DFCI. “It was my privilege<br />
to welcome Larry to Nantucket and celebrate his efforts for both<br />
Dana-Farber and the Red Sox,” said Cloutier.<br />
<strong>The</strong> evening also benefited Nantucket Cottage Hospital’s Community<br />
and Home Health Department.<br />
Swimmers make a splash<br />
in the fight against cancer<br />
On July 22, 45 swimmers, including seven Olympians, put their<br />
best strokes forward in the 10th annual Boston Harbor Island<br />
Swim. Dedicated men and women broke through the waves of<br />
chilly Boston Harbor in a 22-mile relay race starting and ending at<br />
Rowes Wharf. <strong>The</strong> following day, more than 100 participants<br />
made a mad dash for the sea and took part in the Nantasket<br />
Beach Swim, completing either a half-mile or one-mile course.<br />
<strong>The</strong> two days of aquatic events were hosted by Boston’s<br />
Swim Across America program and provided determined swimmers<br />
a chance to improve life after cancer for survivors of the disease.<br />
Together, their efforts raised $180,000 for the David B.<br />
Perini, Jr. Quality of Life Clinic at Dana-Farber.<br />
<strong>Impact</strong> <strong>Summer</strong> <strong>2005</strong><br />
5
Rick Corman continues to “red flag”<br />
multiple myeloma<br />
Rick Corman’s latest gift of $250,000<br />
has brought his philanthropy to Dana-<br />
Farber across the $1 million mark—<br />
and he says this is just the beginning. Corman<br />
supports multiple myeloma research by<br />
Kenneth Anderson, MD, Paul Richardson,<br />
MD, and their colleagues in DFCI’s Jerome<br />
Lipper Multiple Myeloma Center.<br />
Diagnosed with multiple myeloma in 2001,<br />
Corman vowed to give $250,000 annually as<br />
long as he continues his successful fight<br />
against the rare blood cancer. For four years,<br />
Corman, clad in a bright red blazer, has handdelivered<br />
his gift to Dana-Farber, displaying<br />
confidence in and admiration for the physician-scientists<br />
in the Lipper Center.<br />
“I’m in business and I’ve found that money<br />
motivates many people, but not this research<br />
team,” said Corman, owner and founder of<br />
Over four years, Rick Corman has given<br />
$1 million to DFCI to spur development of<br />
effective multiple myeloma therapies.<br />
Nicholasville, Ky.-based RJ Corman Railroad,<br />
LLC. “<strong>The</strong>y are driven by something different—a<br />
passion to kill the disease before it<br />
kills us.”<br />
Corman’s philanthropy is inspired by the<br />
remarkable advances Anderson, Richardson,<br />
and fellow DFCI investigator Teru<br />
Hideshima, MD, PhD, have made against<br />
multiple myeloma. “<strong>The</strong>y have changed treatment<br />
in extraordinary ways.”<br />
For its part, the Lipper Center team agrees<br />
that Corman has helped spur progress. “Rick<br />
has become both a dear friend and a patient<br />
loved by all,” said Richardson. “His courage<br />
and commitment have been simply tremendous,<br />
and his generosity of spirit is inspirational.”<br />
Anderson says, “His kindness has<br />
helped caregivers and patients alike. We are<br />
lucky to have him on our team!”<br />
Aaron Foundation gift funds<br />
groundbreaking Kinase Project<br />
Send a message of hope<br />
this holiday season<br />
Since its establishment, the Aaron Foundation has been offering<br />
financial support to organizations and programs that make a<br />
positive impact in the world of education, culture, and science.<br />
Most recently, the foundation turned this altruistic focus to Dana-<br />
Farber with a $100,000 grant directed toward the Institute’s Kinase<br />
Project. This revolutionary research initiative aims to probe the genetic<br />
mutations that lead to cancer development<br />
and identify potential drugs to target<br />
these specific anomalies.<br />
“This research has far-reaching and crossfunctional<br />
potential, as its results could lead<br />
to a better understanding of a number of<br />
cancers,” said Aaron Foundation Trustee<br />
James Rabb, MD. “With the lifesaving<br />
possibilities so great, we see it as a good<br />
place to put our support.”<br />
“<strong>The</strong> hope is that this research will<br />
lead in the direction where it can do<br />
the most good—helping people overcome<br />
their diseases,” added Rabb’s<br />
David Livingston, MD, is leading DFCI’s cousin and fellow foundation trustee,<br />
Kinase Project, a pioneering research Jane Rabb, PhD.<br />
endeavor set to change the future of<br />
Led by David Livingston, MD, deputy<br />
cancer care and research.<br />
director of the Dana-Farber/Harvard<br />
Cancer Center and the Emil Frei Professor of Genetics and Medicine at<br />
Harvard Medical School, along with DFCI colleagues Matthew<br />
Meyerson, MD, PhD, and William Sellers, MD, this groundbreaking<br />
study will specifically examine some 150 different kinases, or cell<br />
enzymes, that have been found to aid cancer development when mutated.<br />
“This generous gift from the Aaron Foundation is important<br />
in helping us move forward with this critical research. Our overarching<br />
goal is to make available to cancer patients new treatments<br />
that are safer and more effective than the ones currently available,”<br />
said Livingston.<br />
Show your commitment to fighting cancer by purchasing<br />
a box of holiday greeting cards. All proceeds will benefit<br />
Dana-Farber’s lifesaving mission.<br />
Visit www.jimmyfund.org/holiday to view a selection of festive designs<br />
and order your cards, or call Charles Savicki at (617) 632-5420.<br />
CHAMPION<br />
A WINNING CAUSE<br />
Get into the spirit of the season. Choose from these one-of-a-kind<br />
Boston Red Sox and New England Patriots collectible ornaments.<br />
All proceeds from these limited edition pieces will benefit the<br />
<strong>Jimmy</strong> <strong>Fund</strong> and Dana-Farber's lifesaving mission. To order,<br />
please visit us online at www.jimmyfund.org/holiday or call<br />
Charles Savicki at (617) 632-5420.<br />
(ornament size: approximately 2.5” x 3”)<br />
6 <strong>Impact</strong> <strong>Summer</strong> <strong>2005</strong>
Need the perfect gift? Visit www.dana-farber.org/celebration-tribute.<br />
Sacklers steer support for rare cancer<br />
Raymond Sackler, MD, and his wife,<br />
Beverly, are international philanthropists<br />
who have long championed the arts and<br />
sciences. One scientific area they have specifically<br />
supported has been research into carcinoid<br />
and neuroendocrine tumors, rare cancers<br />
that do not typically attract significant funding.<br />
With the help of their Chief Scientific<br />
Officer Arnold Levine, PhD, the couple have<br />
assembled the foremost talent in the field.<br />
<strong>The</strong>ir interest led them to two noted Dana-<br />
Farber investigators: Matthew Meyerson,<br />
MD, PhD, and Matthew Kulke, MD. After<br />
initially supporting these scientists’ work in<br />
2003, the Sacklers have given new gifts of<br />
$500,000 and $250,000 to Meyerson and<br />
Kulke, respectively.<br />
“Drs. Meyerson and Kulke have proposed<br />
and partially accomplished goals that will significantly<br />
contribute to the basic science and<br />
clinical understanding of carcinoid and neuroendocrine<br />
cancers,” said Evan Vosburgh, MD, executive director of the<br />
Raymond and Beverly Sackler Foundation. “We hope that their work will<br />
help educate and motivate others to pursue research in this area, and that they<br />
will be successful at obtaining continued support to expand their research.”<br />
With continued support from Raymond and Beverly Sackler, DFCI’s<br />
Matthew Kulke, MD, (left) and Matthew Meyerson, MD, PhD,<br />
(right) are uncovering the genetic causes of neuroendocrine tumors.<br />
Delving deeper<br />
<strong>The</strong> Sacklers’ backing has led Meyerson and his<br />
team to uncover the function of once-mysterious<br />
proteins that play a critical role in the development<br />
of neuroendocrine cancer. <strong>The</strong>y studied tumor<br />
suppressor proteins that normally prevent neuroendocrine<br />
cancer but are inactivated in the tumors.<br />
Additionally, they found that two such proteins,<br />
menin and parafibromin, control gene activity and<br />
that this activity is deficient in the tumors.<br />
“This discovery opens new opportunities for the<br />
treatment of neuroendocrine tumors and for cancer<br />
therapies more generally,” said Meyerson.<br />
For Kulke, early support from the Sacklers<br />
helped him to build a database of neuroendocrine<br />
patients’ clinical information and blood and tumor<br />
samples. With the couple’s new gift, Kulke’s team<br />
is leveraging this repository, which now comprises<br />
more than 250 patients, to pinpoint the pathways<br />
involved in tumor development and uncover clues<br />
for treatment strategies.<br />
“Through their early support of Dana-Farber’s neuroendocrine tumor<br />
research, the Sacklers planted a seed that has rapidly grown and is already bearing<br />
fruit,” said Kulke. “We are incredibly grateful for their initial and continuing<br />
support of our efforts.”<br />
Verizon <strong>Jimmy</strong> <strong>Fund</strong> Scooper Bowl<br />
dishes up enthusiastic support<br />
Thousands of ice cream lovers<br />
flocked to the Verizon <strong>Jimmy</strong><br />
<strong>Fund</strong> Scooper Bowl June 7, 8,<br />
and 9 on Boston’s City Hall Plaza to<br />
indulge in their favorite frozen treats<br />
and to support New England’s favorite<br />
charity. <strong>The</strong> 23rd annual outdoor festival<br />
kicked off the lazy, hazy days of<br />
summer in grand style by raising its<br />
largest amount ever—more than<br />
$190,000—for the <strong>Jimmy</strong> <strong>Fund</strong> and<br />
Dana-Farber.<br />
<strong>The</strong> all-you-can-eat event attracted<br />
people of all ages, from hungry city<br />
workers enjoying their lunchtime<br />
breaks to schoolchildren holding<br />
hands on class outings. This year, they<br />
had their pick of more than 65 flavors<br />
of ice cream, frozen yogurt,<br />
and sorbet, including “Curse<br />
Reversed,” which celebrates the world<br />
championship Boston Red Sox,<br />
“Baseball Nut,” “Fenway Fudge,”<br />
“Thunder’N’Lightning,” and the<br />
“Last Straw,” provided by 10 generous<br />
companies (see sidebar).<br />
“This is always a wonderful event,<br />
and we are grateful to the people of<br />
Boston for welcoming the Scooper<br />
Bowl year after year with such enthusiasm,”<br />
said Mike Andrews, chairman of<br />
the <strong>Jimmy</strong> <strong>Fund</strong>. “We are especially<br />
thankful to the participating companies,<br />
which contributed more than<br />
10,000 gallons of ice cream, and to<br />
Verizon and all our sponsors for making<br />
this event a great success.”<br />
Title Sponsor: Verizon<br />
Vendors:<br />
Baskin-Robbins<br />
Ben & Jerry’s<br />
Brigham’s /Élan<br />
Cold Stone Creamery<br />
Edy’s Grand Ice Cream<br />
Garelick Farms<br />
Good Humor-Breyer’s Ice Cream<br />
Häagen-Dazs ®<br />
Blue skies and soaring temperatures made the<br />
Scooper Bowl the place to be for (left to right)<br />
Tykera and Isis Williams.<br />
Thank you to our generous supporters<br />
H.P. Hood<br />
Kemps ®<br />
In-kind Sponsors:<br />
Champion Expo Nationwide<br />
GE Capital<br />
Poland Spring<br />
Solo Cup Company<br />
Media Sponsors:<br />
Boston.com<br />
Community Newspaper Company<br />
Sunday, October 9, <strong>2005</strong><br />
B.A.A. HALF MARATHON<br />
Presented by Dana-Farber Cancer Institute and the <strong>Jimmy</strong> <strong>Fund</strong><br />
You are invited to join the Dana-Farber Runners in the race<br />
toward the ultimate finish line: a world without cancer.<br />
For more details and online registration information, log on to www.jimmyfund.org/half-marathon or call (617) 632-1970.<br />
<strong>Impact</strong> <strong>Summer</strong> <strong>2005</strong> 7
<strong>Impact</strong> is now available online at www.dana-farber.org/impact.<br />
Stop & Shop Triple Winner Game, continued from page 1<br />
received a scratch ticket guaranteed to win them food products, gift cards, or<br />
cash prizes up to $10,000. This win-win scenario, along with the support of the<br />
promotion’s co-sponsor, the Boston Red Sox, has propelled the promotion to<br />
become the <strong>Jimmy</strong> <strong>Fund</strong>’s most successful corporate fundraiser.<br />
A winning cause<br />
<strong>The</strong> company’s contributions to the Stop &<br />
Shop Clinic since its establishment have made<br />
a tremendous impact in Dana-Farber’s battle<br />
against pediatric brain tumors. Fueled by Stop &<br />
Shop’s generosity, the clinic has evolved over the last<br />
eight years into what is widely regarded to be the<br />
most comprehensive pediatric brain cancer center<br />
operating in the world today.<br />
Under the leadership of DFCI’s Mark Kieran, MD,<br />
PhD, director of Pediatric Medical Neuro-Oncology, a dedicated team of neurologists,<br />
oncologists, researchers, and support staff works tirelessly to break<br />
through the mysteries that surround this terrible disease in an effort to develop<br />
therapies that will translate into lives saved.<br />
Fueled by Stop & Shop’s resources, the center has created a number of cuttingedge<br />
programs designed to heal patients everywhere. One<br />
recent initiative was the establishment of a laboratory at<br />
Dana-Farber that utilizes the expertise of the Institute’s<br />
researchers while tapping into the knowledge of pediatric<br />
brain cancer specialists and scientists across the globe.<br />
This integration of resources has the potential to lead<br />
to the scientific breakthroughs that can be rendered<br />
into therapies for patients at a more rapid rate.<br />
“Thanks to Stop & Shop, we have been able to<br />
translate multiple discoveries into a better understanding of<br />
pediatric brain tumors, discoveries that would not have happened without their<br />
continued support over the last 15 years,” said Kieran. “Without Stop & Shop,<br />
all of the groundbreaking work now being conducted every day would not<br />
be possible.”<br />
Caring for Carcinoid<br />
Foundation links lab, clinic<br />
in search of a cure<br />
<strong>The</strong> Caring for Carcinoid Foundation has given $500,000<br />
to support the laboratory research of DFCI’s Ramesh<br />
Shivdasani, MD, PhD. This funding follows an earlier<br />
gift of $250,000 to support the clinical research of Dana-Farber’s<br />
Matthew Kulke, MD. Together, these two gifts connect the work<br />
from the lab and clinic.<br />
<strong>The</strong> foundation created this link to rapidly achieve its mission<br />
to discover a cure for carcinoid. At<br />
age 29, Nancy O’Hagan was diagnosed<br />
with this rare gastrointestinal<br />
neuroendocrine cancer. She<br />
and her husband, Patrick, founded<br />
the non-profit foundation in<br />
December 2004.<br />
“<strong>The</strong> Caring for Carcinoid<br />
Foundation simultaneously funds<br />
genetic, molecular, and clinical<br />
research,” said Nancy. “Lab-clinic<br />
collaboration brings together multiple<br />
disciplines to foster creativity<br />
Ramesh Shivdasani, MD, PhD, is determining and insight in each area of<br />
how normal cells might transform into neuroendocrine<br />
tumors, thanks to support from<br />
research, and it will ultimately<br />
the Caring for Carcinoid Foundation. accelerate the path to a cure for<br />
carcinoid cancer.”<br />
Experts now believe that future cures for cancer will be in the<br />
form of targeted therapies. <strong>The</strong>se therapies require first that<br />
cancer is understood at the level of the target cell. <strong>The</strong> foundation’s<br />
gift will make this type of research possible. Shivdasani’s<br />
lab will map the molecular basis and biological pathways of<br />
normal gastrointestinal (GI) cell development and differentiation.<br />
Such a map will enable him to determine how normal GI<br />
cells become malignant.<br />
By bringing this science to neuroendocrine tumors, he aims<br />
to outline the key pathways of neuroendocrine cell growth.<br />
Shivdasani’s research will link with Kulke’s research to yield<br />
innovative, targeted therapies.<br />
“<strong>The</strong> Caring for Carcinoid Foundation recognizes that<br />
Dana-Farber is unique among cancer institutes for fostering<br />
this partnership,” Shivdasani said. “It is our hope that by<br />
working collaboratively, we will identify potential drug targets<br />
to treat this disease.”<br />
New York Evening opens<br />
doors to novel research<br />
On June 8, Institute Trustee David Dechman welcomed<br />
Dana-Farber supporters from the metropolitan New York<br />
area for an evening of fellowship at the New York Yacht<br />
Club. Above: Evening host Dechman greeted <strong>Jimmy</strong> <strong>Fund</strong><br />
Visiting Committee member Terry Bovin (right) and featured<br />
speaker Karen Albritton, MD, (left) director of Dana-Farber’s<br />
newly established Adolescent and Young Adult (AYA)<br />
Oncology Program.<br />
Guests had the unique opportunity to learn about an<br />
emerging area of cancer research directly from a distinguished<br />
physician-scientist. In her presentation entitled,<br />
“A New Focus: <strong>The</strong> Lost Generation of Cancer Patients,”<br />
Albritton explained how the AYA Program is leading the<br />
way to improve treatment options for patients ages 15–40<br />
and working to address the unique needs of this group.<br />
NEED THE<br />
perfect<br />
GIFT?<br />
Look No Further<br />
Celebration and Tribute Gifts are a unique way to<br />
remember someone special or to celebrate birthdays,<br />
weddings, anniversaries, and other occasions while<br />
supporting Dana-Farber’s lifesaving work.<br />
Make a gift of $25 or more, and we’ll send a personalized<br />
greeting card to the special person of your choice within 24 hours.<br />
Visit www.dana-farber.org/celebration-tribute<br />
to learn more, or call Kim Goff at (617) 632-3146.<br />
8 <strong>Impact</strong> <strong>Summer</strong> <strong>2005</strong>
Dodge gift bolsters support for<br />
“lost generation” of patients<br />
Receiving a cancer diagnosis means<br />
confronting complicated emotions<br />
and difficult decisions. This diagnosis<br />
can be especially difficult for young<br />
adults who are facing other life changes<br />
such as completing college or entering<br />
the workforce.<br />
Active members of the Dana-Farber<br />
community, Institute Trustee Steven<br />
Dodge and his wife, Anne, understand the<br />
unique challenges faced by cancer patients<br />
ages 15–40 and their families. <strong>The</strong>ir<br />
recent gift of $500,000 supports DFCI’s<br />
new Adolescent and Young Adult (AYA)<br />
Oncology Program, which engenders<br />
research that is changing how physicians<br />
care for younger patients, and provides<br />
momentum for the Institute’s planned<br />
comprehensive capital campaign.<br />
“Anne and I have long supported<br />
the <strong>Jimmy</strong> <strong>Fund</strong>’s youthful spirit and<br />
commitment to Dana-Farber’s youngest<br />
patients,” said Steven Dodge. “By helping<br />
fund the AYA Program, we hope to<br />
reach out to an underserved population<br />
and make a difference in the lives of<br />
young adults.”<br />
Directed by Karen Albritton, MD, the<br />
AYA Program is examining how one-sizefits-all<br />
approaches to treating cancer<br />
patients may create what Albritton calls<br />
a “lost generation.” Albritton’s research<br />
points to alarming deficits in the treatment<br />
of adolescents and young adults<br />
with this disease. She suggests this<br />
younger age group’s cancer problem<br />
(approximately 70,000 diagnoses per<br />
year in the U.S.) has been overshadowed<br />
by the sheer volume of cancers in older<br />
populations (more than 700,000 diagnoses<br />
annually).<br />
“Cancer treatment specifically focused<br />
on adolescents and young adults has typically<br />
lagged behind that of their older and<br />
<strong>The</strong> AYA Program at Dana-Farber is committed<br />
to improving treatment for younger<br />
cancer patients like Mike Violandi, who was<br />
diagnosed with leukemia at age 30.<br />
younger counterparts,” Albritton said.<br />
“<strong>The</strong>re has been an unmet need for targeted<br />
clinical and research programming<br />
and attention to the unique needs of this<br />
generation. With the Dodges’ gift, we can<br />
take a leadership role in providing services<br />
to this age group and begin to reduce<br />
these inequities.”<br />
With support like the Dodges’, the AYA<br />
Program will help return these patients to<br />
the important task of embarking on their<br />
journeys through adult life.<br />
<strong>Jimmy</strong> <strong>Fund</strong> Regatta sets<br />
a course for curing cancer<br />
Employers, employees<br />
unite to fight cancer<br />
This year,<br />
thousands of<br />
individuals<br />
helped fight cancer<br />
by giving to Dana-<br />
Farber and the<br />
<strong>Jimmy</strong> <strong>Fund</strong> at<br />
work. <strong>The</strong> combined<br />
effort of these<br />
generous employees<br />
and nearly 120 host<br />
companies raised<br />
$500,000 for cutting-edge<br />
research letter carrier with the United States<br />
Lisa Sims-Okundaye, a 19-year<br />
and compassionate Postal Service, has been a steadfast<br />
supporter of Dana-Farber’s workplace<br />
patient care through<br />
giving campaign.<br />
DFCI’s annual<br />
workplace giving campaign.<br />
“During our annual United Way campaign, NSTAR<br />
encourages our employees to make contributions to the<br />
charitable causes that are important to them and their<br />
families, including great organizations like Dana-Farber,”<br />
said NSTAR CEO and Institute Trustee Thomas May.<br />
“This is a great way for NSTAR to give back to the communities<br />
we serve.”<br />
People as far away as Hawaii made gifts ranging from<br />
$5–$25,000 through employer-sponsored fund drives,<br />
United Way designations, and one-time and monthly<br />
gifts made directly to DFCI. Additionally, government<br />
employees, including those serving overseas in the<br />
Armed Forces, participated through the Combined<br />
Federal Campaign (CFC).<br />
“With my gifts, I hope that Dana-Farber’s doctors can<br />
wipe out cancer altogether,” said Lisa Sims-Okundaye, a<br />
letter carrier with the United States Postal Service who<br />
has supported DFCI through the CFC for more than<br />
10 years. “I don’t like to see people sick, especially kids.<br />
My hope is that these patients will get better so that<br />
they can enjoy their lives.”<br />
Consider setting up a workplace giving campaign to<br />
benefit Dana-Farber at your place of employment or let us<br />
help you increase participation in your United Way campaign.<br />
Visit us online at www.dana-farber.org/give-atwork,<br />
or call Maxine Neil at (617) 632-3492.<br />
give from your heart<br />
“Dana-Farber helped extend my<br />
mother’s life 20 years after her<br />
diagnosis. Naming a chair was<br />
the perfect way to memorialize<br />
her and honor my family<br />
in a lasting way.”<br />
— Bill Murphy<br />
<strong>The</strong> sailing community turned out in full<br />
force for the inaugural <strong>Jimmy</strong> <strong>Fund</strong> Regatta,<br />
held in Newport, R.I., on June 4–5.<br />
Presented by financial services company<br />
Northern Trust and co-chaired by Nancy<br />
Stratton and David Ford, the two-day<br />
racing event featured avid yachters and<br />
boating enthusiasts who took to the high<br />
seas for a great cause—helping the <strong>Jimmy</strong><br />
<strong>Fund</strong> and Dana-Farber make waves against<br />
cancer. With a highly competitive regatta,<br />
a fun-filled “Sail for <strong>Jimmy</strong>” race, and a<br />
dinner and awards presentation, the successful,<br />
first-time event brought in a<br />
fundraising total of more than $180,000.<br />
Left to right: DFCI Chief of Staff<br />
Stephen E. Sallan, MD; Institute Trustee<br />
Charles A. Dana III, owner of <strong>Jimmy</strong> <strong>Fund</strong><br />
Regatta host site Newport Shipyard; and<br />
<strong>Jimmy</strong> <strong>Fund</strong> Chairman Mike Andrews<br />
gathered together as the sun set on the<br />
opening day of the sailing event.<br />
Cancer has touched all of us. Name a chair in the<br />
<strong>Jimmy</strong> <strong>Fund</strong> Auditorium and create a lasting tribute<br />
to a family member, friend, or colleague.<br />
Your gift of $10,000 forever links that special person<br />
to DFCI’s lifesaving mission.<br />
To read more personal stories or to name a chair<br />
online, visit www.jimmyfund.org/chairs or call<br />
Maxine Neil at (617) 632-3492.<br />
Your gift of $10,000 can be made in two payments.<br />
Nearly half of the chairs have been named.<br />
<strong>Impact</strong> <strong>Summer</strong> <strong>2005</strong><br />
9
Myeloma Research <strong>Fund</strong> promotes national collaboration<br />
<strong>The</strong> Myeloma Research <strong>Fund</strong> is enabling<br />
Kenneth Anderson, MD, and his colleagues<br />
at Dana-Farber to work collaboratively<br />
with other national cancer<br />
experts to increase the pace of discovery.<br />
When Lew Aronson was in his mid-30s, he was<br />
treated for the rare blood cancer multiple<br />
myeloma. This experience inspired him to<br />
raise $2 million and establish the Myeloma Research<br />
<strong>Fund</strong> (MRF), a catalyst for collaboration<br />
between leading<br />
national researchers.<br />
Now, Dana-Farber’s Kenneth<br />
Anderson, MD, director of the<br />
Jerome Lipper Multiple Myeloma<br />
Center at DFCI and the Kraft<br />
Family Professor of Medicine at<br />
Harvard Medical School, has<br />
been awarded his fourth consecutive MRF grant. This<br />
new $190,000 gift, which brings the MRF’s cumulative<br />
funding to DFCI to $940,000, will help Anderson conduct<br />
important drug discovery and validation in concert<br />
with cancer experts across the country.<br />
“Working together with myeloma<br />
investigators in Florida and<br />
California … we can do more<br />
than any one center could<br />
do alone.”<br />
Aronson’s cancer went into remission following a bone<br />
marrow transplant in 2000. He explained that MRF’s goal<br />
is to find a cure—or method of infinite control—of multiple<br />
myeloma in the shortest practical period.<br />
“Dr. Anderson’s team combines<br />
basic scientific studies of the biochemical<br />
pathways involved in the survival<br />
and proliferation of the myeloma cell<br />
with clinical trials of new compounds<br />
which can interrupt those pathways,”<br />
said Aronson.<br />
Anderson firmly believes that collaborative<br />
approaches to research increase<br />
the pace of progress in identifying and validating new targeted<br />
therapies. “Thanks to the Myeloma Research <strong>Fund</strong>,<br />
our team is working together with myeloma investigators<br />
in Florida and California,” said Anderson. “Together, we<br />
can do more than any one center could do alone.”<br />
— Kenneth Anderson, MD<br />
PMC, continued from page 1<br />
As he has since 1980, PMC Founder<br />
and Executive Director Billy Starr<br />
takes on the challenging two-day<br />
course from Sturbridge to<br />
Provincetown, Mass.<br />
<strong>The</strong> next 25 rides<br />
After celebrating its 25th anniversary last year, the PMC is looking<br />
forward to making the next quarter century as successful as the last.<br />
As always, this level of achievement depends on the riders’ passion and<br />
heartfelt commitment to the cause. <strong>The</strong> PMC is also expanding its<br />
programs to bring its fundraising for the <strong>Jimmy</strong> <strong>Fund</strong> to new heights.<br />
One such initiative is the PMC Kids Ride program, which encourages<br />
children to embrace philanthropy at an early age. This year, 1,500<br />
kids participated in 15 Kids<br />
Rides, which together raised a<br />
total of $150,000. “<strong>The</strong> Kids<br />
Rides are the future of the<br />
PMC,” Starr said.<br />
After the children graduate<br />
from the Kids Rides, Starr hopes<br />
the young cyclists will join the<br />
main event. Emily Bekenstein is<br />
a young rider who started participating<br />
in the PMC when she<br />
was 15 years old. This year<br />
marked her third PMC. Since<br />
2003, she has raised more than<br />
$72,000. Bekenstein’s parents,<br />
Anita and Josh, are longtime<br />
PMC cyclists; Josh is also a<br />
Dana-Farber trustee and PMC<br />
board member. As cyclists of all<br />
ages continue to rise to the<br />
challenge, the PMC’s important<br />
legacy will live on well<br />
into the future.<br />
<strong>The</strong> PMC is reaching out to<br />
additional supporters in another<br />
innovative way through its Many participants, like William Teseira of East Boston,<br />
Mass., ride to honor a loved one’s battle with cancer.<br />
Virtual Rider program, which<br />
enables people who do not ride<br />
over PMC weekend to travel a different route or participate in another<br />
activity to further the organization’s mission of funding cancer research.<br />
Sixty-one-year-old Dan Healey of Randolph, Mass., is a Virtual Rider<br />
who, in late May, set out to cycle across the country for the PMC. It was<br />
his second cross-country ride, but this time his focus lay solely on beating<br />
his brain cancer. Healey, a patient at Dana-Farber, knows firsthand<br />
how important it is to raise money for medical research.<br />
“Medical science has nearly eliminated polio and childhood leukemia,”<br />
Healey said. “Someday, we may be able to say that the PMC helped<br />
defeat cancer.”<br />
Katelynn’s Ride cycles<br />
past $500,000 mark<br />
Nearly 300 riders pedaled their way<br />
through Western Massachusetts on June 5<br />
for the fifth annual Katelynn’s Ride<br />
fundraiser. This virtual ride of the Pan-<br />
Massachusetts Challenge bike-a-thon is<br />
held annually in memory of Katelynn<br />
Battista, a Dana-Farber patient who lost<br />
her courageous battle with cancer in 1997<br />
at age 11.<br />
Organized by Katelynn’s parents,<br />
Michele and Domenic Battista, and event<br />
directors Steven Stark, Dan Williams, and<br />
Kim Zachary, the ride raised $125,000—an<br />
additional $4,000 came in after event<br />
day—for the <strong>Jimmy</strong> <strong>Fund</strong> this year, surpassing<br />
its five-year, $500,000 goal. This<br />
generous gift will support pediatric cancer<br />
research and care, and it will name a<br />
<strong>Jimmy</strong> <strong>Fund</strong> Clinic infusion room in<br />
Katelynn’s memory.<br />
Left to right: Dan Williams, Kim<br />
Zachary, Michele Battista, Steven Stark,<br />
and Domenic Battista celebrated Katelynn’s<br />
life and this year’s successful ride.<br />
STEP UP TO<br />
THE PLATE!<br />
Support your favorite baseball team and<br />
New England’s favorite charity by sporting<br />
the official <strong>Jimmy</strong> <strong>Fund</strong>/Boston Red Sox<br />
Massachusetts license plate on your car.<br />
Go to<br />
www.jimmyfund.org/plate<br />
to order your plate.<br />
10 <strong>Impact</strong> <strong>Summer</strong> <strong>2005</strong>
Log on to www.dana-farber.org and help conquer cancer.<br />
Smith Family Foundation<br />
grant advances study of<br />
new therapies<br />
Support for critical translational<br />
research efforts can be difficult to<br />
find, so DFCI’s Anthony Letai,<br />
MD, PhD, and Scott Armstrong, MD,<br />
PhD, are thankful to be advancing<br />
their cutting-edge work with Smith<br />
Family New Investigator Awards. <strong>The</strong><br />
two-year, $200,000 grants, established<br />
by the Richard and Susan<br />
Smith Family Foundation, will allow<br />
Letai and Armstrong to investigate<br />
improved treatments for chronic<br />
lymphocytic leukemia (CLL) and<br />
childhood leukemia, respectively.<br />
Begun by the foundation in 1991<br />
and administered by <strong>The</strong> Medical<br />
Foundation, the annual awards are<br />
bestowed upon promising scientists<br />
early in their careers, before they are<br />
eligible for major grant support.<br />
“We are particularly proud to<br />
support young scientists from Dana-<br />
Farber as Smith Family New<br />
Investigators,” said Institute Trustee<br />
Richard Smith, co-chair of the foundation’s<br />
board of trustees. “Translational<br />
research is Dana-Farber’s great strength,<br />
and research by Drs. Letai and Armstrong<br />
promises to lead the way to new leukemia<br />
therapies.” <strong>The</strong> Smith family is a longtime<br />
Institute supporter; the Richard A.<br />
and Susan F. Smith Laboratories at<br />
DFCI are named in their honor.<br />
Letai will use his grant to build on<br />
earlier research with his late DFCI colleague,<br />
Stanley J. Korsmeyer, MD, to<br />
identify chemical compounds targeting<br />
the molecule BCL-2, shown to block cell<br />
death, which may be candidates for clinical<br />
trials. Armstrong will put his award<br />
to work researching childhood leukemia’s<br />
development and using his findings to<br />
craft more effective treatments.<br />
Photo by Michael Thompson<br />
KEY TO THE CURE<br />
OCTOBER 28 AND 29<br />
Join Saks Fifth Avenue for our annual shopping event to support Key To <strong>The</strong> Cure,<br />
a charitable initiative to fight women’s cancers.<br />
A percentage of sales up to $1 million will be donated to local and national<br />
women’s cancer charities through the Women’s Cancer Research <strong>Fund</strong>,<br />
a program of the Entertainment Industry Foundation. To order the limited edition<br />
T-shirt designed by Diane von Furstenberg, or for more information about this event,<br />
call 888.771.2323 or visit saks.com. Mercedes-Benz USA, LLC will make a<br />
generous donation of $1 million to Saks Fifth Avenue’s Key To <strong>The</strong> Cure<br />
through the sale of 750 Signature Edition R-Class vehicles.<br />
Special thanks to Hilary Swank, the <strong>2005</strong> Ambassador for<br />
EIF’s Women’s Cancer Research <strong>Fund</strong> and Saks Fifth Avenue’s Key To <strong>The</strong> Cure.<br />
SAVING LIVES<br />
IS ALWAYS IN FASHION<br />
Anthony Letai, MD, PhD, (left) and<br />
Scott Armstrong, MD, PhD, (above, left)<br />
received Smith Family New Investigator<br />
Awards that will help advance their<br />
research into improved therapies for<br />
specific leukemias.<br />
Join QVC and the Fashion Footwear Association<br />
of New York and take a step toward eradicating<br />
breast cancer in the 12th annual Shoes on Sale ® .<br />
Choose from a wide array of designer and brandname<br />
shoes at half their suggested price. All proceeds<br />
benefit breast cancer research and education at<br />
Dana-Farber and other centers around the country.<br />
For more information contact:<br />
Sarah Curtis at (617) 632-5091<br />
or via e-mail at<br />
sarah_curtis@dfci.harvard.edu<br />
Style and hope meet on the runway<br />
High fashion and the battle against cancer took<br />
center stage on May 20 at the Hyatt Regency<br />
Boston during “Couture for Hope,” an<br />
elegant luncheon and fashion show to benefit the<br />
Women’s Cancers Program at Dana-Farber Cancer<br />
Institute. Hosted by Neiman Marcus and organized<br />
by Honorary Chair Susan Smith and event co-chairs<br />
Deborah First, Institute Trustee Patricia Franchi, and<br />
Boston Red Sox wives Kathryn Nixon and Karen<br />
Varitek, this event raised an impressive $160,000.<br />
Neiman Marcus has helped raise hundreds of thousands<br />
of dollars for cancer research and patient care<br />
and has been a generous supporter of numerous<br />
Dana-Farber events, including the kickoff party for<br />
the <strong>2005</strong> Palm Beach, Fla., fundraising season.<br />
“Neiman Marcus feels very strongly about givingback<br />
to the community,” said Lesley Greer, general<br />
On the eve of Couture for Hope, Boston Red Sox<br />
players Trot Nixon (second from left) and Jason Varitek<br />
and their wives, Kathryn Nixon (left) and Karen<br />
Varitek (right), hosted a private dinner for guests to<br />
meet designer Carolina Herrera (middle).<br />
manager and vice president of Neiman Marcus<br />
Boston. “Dana-Farber has such a tremendous impact<br />
on improving the lives of so many. It is our honor to<br />
support this cause.”<br />
Internationally renowned fashion designer<br />
Carolina Herrera lent the simple elegance of her<br />
designs to the highlight of the afternoon: an exclusive<br />
runway show and preview of her fall <strong>2005</strong> collection.<br />
Joyce Kulhawik, arts and entertainment anchor<br />
for Boston’s CBS4-TV, emceed the fashion show.<br />
She was also the recipient of the Susan F. Smith<br />
Inspiration Award, which is presented annually to<br />
individuals who motivate and improve the lives of<br />
those with cancer. Having battled the disease three<br />
times herself, Kulhawik is an inspiration to many<br />
and a strong advocate in the search for cures.<br />
<strong>Impact</strong> <strong>Summer</strong> <strong>2005</strong><br />
11
Register for an event at www.jimmyfund.org.<br />
Sherwood, Kotkowski, Maffei families establish<br />
enduring memorial<br />
When Daryl Layzer lost her battle with multiple myeloma, her family<br />
wanted to thank her team of Dana-Farber physicians—led by Kenneth<br />
Anderson, MD—and help ensure future patients received the same compassionate<br />
care and had effective new treatment options available to them.<br />
Layzer’s mother, Rosemary Kotkowski; husband, Jim Maffei; and sister and<br />
brother-in-law, Emily and Ned Sherwood, banded together to carry out this wish,<br />
giving $1 million to establish the Daryl E. Layzer <strong>Fund</strong> at DFCI in 1998. To expand<br />
this fund, the family recently made an additional $250,000 gift.<br />
“My father talked to me about giving back to those who come after us,” said<br />
Kotkowski. “I believe that the superb care Dr. Anderson gave my daughter was made<br />
possible because of the generosity of those who preceded her.”<br />
<strong>The</strong> Sherwoods could not agree more. <strong>The</strong>y said that Dana-Farber’s bench-to-bedside<br />
model gave Daryl the opportunity to benefit from best practices in the field of<br />
myeloma research while receiving personalized and loving care from Anderson and<br />
his team.<br />
Maffei added, “I saw what Daryl went through, and I want a better world for<br />
myeloma patients.”<br />
“We have three new myeloma drugs—Thalomid ® , Revlimid ® , and Velcade ® —as a<br />
result of the initial support from Daryl’s family,” said Anderson, director of DFCI’s<br />
Jerome Lipper Multiple Myeloma Center and the Kraft Family Professor of Medicine<br />
at Harvard Medical School. “This new gift will help us meet our goal of making<br />
available at least one new drug a year to treat patients.”<br />
Left to right: Ned and Emily Sherwood, Rosemary Kotkowski, and Jim<br />
Maffei believe that Kenneth Anderson, MD, and his DFCI colleagues<br />
are on the fast track to finding a cure for multiple myeloma.<br />
Jazz night hits a high note<br />
for Friends of Dana-Farber<br />
Nearly 300 guests dined and danced the<br />
evening away for a good cause on May 13<br />
at “A Night of Jazz,” hosted by the Friends<br />
of Dana-Farber Cancer Institute, an allvolunteer<br />
organization. <strong>The</strong> eclectic event,<br />
held at the State Room in Boston, raised<br />
more than $400,000 for cancer research<br />
and care through ticket sales and a tribute<br />
book honoring the Bekenstein family for<br />
its continued commitment to DFCI.<br />
Internationally recognized vocalist<br />
Lavay Smith & Her Red Hot Skillet Lickers,<br />
a star-studded eight-piece band, performed<br />
classic jazz and blues numbers in<br />
the authentic style of the 1940s and ‘50s.<br />
During dinner, attendees were treated to<br />
the smooth sounds of the Victor Mendoza<br />
Trio while enjoying panoramic views of<br />
Boston Harbor and the islands.<br />
Left to right: “A Night of Jazz” Cochairs<br />
Kelly Pesek and Maureen Champa<br />
celebrate the event’s resounding success.<br />
For more information about the Friends,<br />
visit www.dana-farber.org/how/friends.<br />
Oracle helps combat ER-negative breast cancer<br />
“Oracle’s funding of<br />
Dr. Brown’s work has<br />
produced very significant<br />
developments, year<br />
after year.”<br />
— Rosalie Gann<br />
Research by Dana-Farber’s Myles Brown, MD,<br />
into estrogen-receptor-negative (ER-negative)<br />
breast cancer caught the eye of Oracle<br />
Corporation. Impressed with his progress using a<br />
technology called RNA interference (RNAi), the<br />
world’s largest enterprise software company has now<br />
made its third $100,000 gift to<br />
help Brown combat this aggressive<br />
form of breast cancer.<br />
“Oracle’s funding of Dr. Brown’s<br />
work has produced very significant developments, year<br />
after year,” said Rosalie Gann, Oracle’s director of giving.<br />
“<strong>The</strong> recent mapping of the human genome and<br />
use of RNAi technology have multiplied the possibilities<br />
of his research exponentially.”<br />
ER-negative cancers account for about one-third<br />
of all breast cancers, or some 65,000 cases a year, in<br />
the United States. ER-negative tumors are so named because<br />
they do not have receptors, or special proteins, that bind<br />
to estrogen.<br />
While this form of the disease is currently difficult to<br />
treat, RNAi is enabling Brown to understand the causal<br />
factors and critical pathways involved in<br />
the growth and malignant behavior of<br />
ER-negative tumors. By eliminating the<br />
product of a specific gene and depriving<br />
the cell of the gene’s activity, RNAi provides<br />
researchers with an advantage in determining the<br />
course of future therapies.<br />
“This technology will ultimately lead to improvements in<br />
the prevention and treatment of these tumors,” said Brown,<br />
chief of Molecular and Cellular Oncology. “Oracle continues<br />
to make it possible for us to increase our understanding<br />
of the forces driving ER-negative breast cancer.”<br />
12 <strong>Impact</strong> <strong>Summer</strong> <strong>2005</strong>
Kimmel Foundation rewards<br />
two translational scientists<br />
<strong>The</strong> Sidney Kimmel Foundation for Cancer<br />
Research has given two $200,000 grants to a<br />
pair of Dana-Farber physician-scientists to<br />
advance their work and improve cancer therapies.<br />
Anthony Letai, MD, PhD, and Ruben Carrasco,<br />
MD, PhD, won prestigious Kimmel Translational<br />
Science Awards, created five years ago to support<br />
physicians who also conduct research.<br />
“<strong>The</strong> foundation recognizes that translational<br />
research is absolutely critical to improving treatment<br />
for cancer,” said Gary Cohen, MD, administrative<br />
director of the Kimmel Foundation. “We are<br />
pleased to support Dana-Farber and these excellent<br />
young physicians. Clearly, they were at the top of<br />
the applicant pool, and I know they will continue<br />
to do great work.” More than 200 researchers vied<br />
this year for the 15 grants the foundation awards<br />
annually to young scientists, including five designated<br />
for physician-scientists.<br />
Letai’s award will enable him to probe the<br />
strategies cancer cells employ to avoid death, and<br />
he will use these findings to develop new therapies.<br />
Carrasco’s prize will help him investigate<br />
specific genes implicated in the pathogenesis of<br />
multiple myeloma, a devastating hematological<br />
malignancy. He will also research genetic lesions<br />
to find novel therapeutic targets and markers to<br />
help diagnose and predict the course of the disease<br />
and treatment outcomes.<br />
“I am very grateful to the Kimmel Foundation<br />
not only for the practical, essential support they are<br />
providing for my research, but also for the honor<br />
they have bestowed in recognizing my laboratory’s<br />
work with this award,” said Letai.<br />
Make Hope<br />
the Guest of Honor<br />
at Your Next Occasion<br />
In place of standard party or event<br />
favors, give a gift that will help find cures<br />
for cancer. Our Special Occasion Favors<br />
inform your wedding, shower, Bar/Bat<br />
Mitzvah, or party guests that a gift has<br />
been made to Dana-Farber in their honor.<br />
Order your Special Occasion Favors online<br />
at www.jimmyfund.org/favors<br />
or call Alicia Gallo at (617) 632-6099<br />
or (800) 52-JIMMY.<br />
Second victory against<br />
melanoma inspires gift<br />
<strong>The</strong> spot on Thalma Cohen de Gruszka’s chest X-ray was alarming. <strong>The</strong><br />
Caracas, Venezuela, native had defeated melanoma in 2000, and four<br />
years later seemed poised for a new battle against mesothelioma (a cancer<br />
of the lining of the lungs). Sent by her doctor to the United States to see specialists<br />
at Dana-Farber, Cohen de Gruszka learned the truth: <strong>The</strong> spot was actually<br />
an unusually located recurrence of melanoma. Her subsequent treatment by<br />
DFCI Melanoma Program Clinical Director F. Stephen Hodi, MD, together<br />
with her positive attitude and love of life, have put her on the road to a second<br />
victory against cancer.<br />
To thank Hodi for his exemplary care and to support his innovative<br />
immunotherapy studies, Cohen de Gruszka has established the $100,000<br />
Gruszka Cohen Family <strong>Fund</strong> for Melanoma Research.<br />
“I was very lucky to be able to come to the United States and to Dana-<br />
Farber,” said Cohen de Gruszka. “I hope this gift will help make treatments like<br />
Dr. Hodi’s available to those who cannot travel here to receive them.”<br />
<strong>The</strong> fund will bolster Hodi’s studies of cancer immunotherapeutics—treatments<br />
that utilize immune-stimulating compounds and a patient’s melanoma<br />
cells to launch a potent anti-tumor immune attack.<br />
“With a better understanding of the effects of different target/drug combinations,<br />
it will be possible to improve on the promising results already seen with<br />
these treatments,” said Hodi. “This support will go a long way toward bringing<br />
about this understanding.”<br />
Marathon Challenge says<br />
“thank you” to top fundraisers<br />
Each year, the Dana-Farber Marathon Challenge (DFMC) offers runners<br />
the opportunity to reach two personal milestones simultaneously—completing<br />
the legendary Boston Marathon ® while raising vital funds to support<br />
the lifesaving work of investigators in the Claudia Adams Barr<br />
Program in Innovative Basic Cancer Research at Dana-Farber. As each<br />
DFMC participant works diligently to raise the individual minimum of<br />
$2,500, there are several dozen team members who emerge to significantly<br />
surpass this point along the fundraising route, hoping to reach the<br />
ultimate finish line: the eradication of cancer.<br />
Those runners whose efforts yielded $10,000 or more in <strong>2005</strong> were<br />
recognized at the DFMC’s annual “10K Team” reception at Dana-Farber<br />
on June 29. <strong>The</strong> event paid tribute to these fundraising pacesetters<br />
(some of whom are pictured here) whose combined contribution of more<br />
than $1.2 million pushed the Marathon Challenge’s overall fundraising<br />
total to $3.4 million.<br />
Give Online<br />
It makes a world of difference to our patients<br />
F. Stephen Hodi, MD, is working to bring effective cancer vaccines to<br />
melanoma patients including Jeanne Myers (pictured here).<br />
Help Dana-Farber continue to make progress against cancer and save lives.<br />
Make your gift online today at www.jimmyfund.org or www.dana-farber.org.<br />
<strong>Impact</strong> <strong>Summer</strong> <strong>2005</strong><br />
13
Gillette expands commitment<br />
to prostate cancer care<br />
In 2004, <strong>The</strong> Gillette Company partnered with Dana-Farber<br />
to tackle racial disparities in prostate cancer screening by<br />
launching <strong>The</strong> Gillette Company Community Prostate Cancer<br />
Screening Program. With a $100,000 gift to DFCI’s Donald<br />
Kufe, MD, the company has now expanded its dedication<br />
to defeating the disease by supporting<br />
research into new treatments, as well.<br />
Gillette’s burgeoning commitment<br />
to Dana-Farber’s prostate cancer<br />
efforts complements the company’s<br />
extensive support for the care of<br />
women’s cancers through the Gillette<br />
Center for Women’s Cancers at<br />
DFCI. <strong>The</strong> prostate screening program,<br />
which uses the Institute’s Blum<br />
Family Resource Center Van to bring<br />
cancer information and testing services<br />
to underserved populations around<br />
<strong>The</strong> Gillette Company is teaming up with Boston, was among the company’s<br />
Donald Kufe, MD, to untangle the complex<br />
relationship between the protein<br />
first forays into prostate health.<br />
“<strong>The</strong> response to the screening program<br />
and the promise of Dr. Kufe’s<br />
MUC1 and prostate cancer.<br />
approach have inspired us to boost<br />
“<strong>The</strong> response to the<br />
our involvement in prostate cancer<br />
care,” said Gillette Vice President for<br />
screening program<br />
Civic Affairs Cathy Chizauskas.<br />
and the promise of<br />
Gillette’s backing will allow Kufe to<br />
examine the mechanisms by which<br />
Dr. Kufe’s approach have the mucous protein MUC1 contributes<br />
to prostate cancer develop-<br />
inspired us to boost our<br />
ment. <strong>The</strong> protein—which is overproduced<br />
in 60–70 percent of<br />
involvement in prostate<br />
cancer care.”<br />
prostate tumors—helps cancer cells<br />
resist radiation and chemotherapy.<br />
“I’m particularly interested to know<br />
— Cathy Chizauskas<br />
how MUC1 interferes with hormone<br />
therapy in prostate cancer,” says Kufe.<br />
“Understanding this, we can develop an assortment of tools to<br />
eliminate MUC1 and counter the resistance.”<br />
Family honors son’s<br />
memory with<br />
pediatric fellowship<br />
Scott and Heidi Smith’s personal battle against pediatric cancers<br />
started with the loss of their 4-year-old son Garrett. Through<br />
the Garrett B. Smith Foundation, the Smiths have enlisted Dana-<br />
Farber’s expertise to realize their vision of eradicating pediatric cancers<br />
by awarding a two-year, $100,000 Garrett B. Smith Term Fellowship<br />
to DFCI’s Charles Roberts, MD, PhD.<br />
“<strong>The</strong> foundation is our way of keeping Garrett’s memory burning<br />
brightly,” said Scott Smith, “and playing some small role in advancing<br />
the fight against children’s cancers.”<br />
Roberts’ fellowship is the ninth awarded nationwide by the Garrett B.<br />
Smith Foundation since 1996, and the first to be given to a Dana-Farber<br />
staff member. This support provides young scientists at established<br />
cancer centers the opportunity to pursue innovative research ideas.<br />
<strong>The</strong> Smiths were connected to Roberts by Robert Soiffer, MD, chief<br />
of Hematologic Malignancies and a longtime friend of Scott’s. “We’ve<br />
known each other since we were 12,” says Soiffer.<br />
“Scott and Heidi do their homework and know what they are looking<br />
for in a potential fellow,” said Soiffer. “I was very pleased to see how<br />
impressed they were with Charlie and his work.”<br />
Roberts’ research focuses on the potentially widespread cancer-causing<br />
capabilities of Snf5, a gene linked to aggressive pediatric tumors. “With<br />
the foundation’s support, I will be able to access the resources I need to<br />
build a fundamental understanding of Snf5’s newly appreciated role in<br />
cancer development,” said Roberts.<br />
<strong>The</strong> Smiths have also made a $50,000 gift to support lymphoma<br />
research at Dana-Farber.<br />
Established by Scott and Heidi Smith (above), the Garrett B. Smith<br />
Foundation is helping Charles Roberts, MD, PhD, gain new insights into the<br />
genetics of pediatric cancers.<br />
American Lung Association gives hope to cancer patients<br />
<strong>The</strong> American Lung Association ® (ALA) is committed<br />
to supporting the promise of national leaders in<br />
lung investigative work. To carry out this mission,<br />
the organization has presented its ALA/LUNGevity<br />
Foundation Research Grant to Dana-Farber’s Matthew<br />
Meyerson, MD, PhD. This $180,000 gift will fund<br />
research into adenocarcinoma, the most common form of<br />
lung cancer.<br />
“<strong>The</strong> results of Dr. Meyerson’s research project will help<br />
further our knowledge of tumor chemotherapy,” said Ray<br />
Vento, project officer for the ALA’s Asthma Clinical<br />
Research Center. “We are proud to have Dr. Meyerson<br />
among the American Lung Association’s awardees, and we<br />
hope that this support provides him the necessary assistance<br />
to further his innovative work.”<br />
<strong>The</strong> American Lung Association’s Nationwide Research<br />
Program, through which this ALA/LUNGevity Foundation<br />
Research Grant was awarded, is designed to support scientists<br />
whose studies may lead to prevention, relief, and cures for lung<br />
diseases. This funding will allow Meyerson to deepen his<br />
research into the identification of chromosomal alterations and<br />
mutations in adenocarcinoma.<br />
Meyerson believes this knowledge could provide clinicians<br />
with more effective means to pinpoint the disease using innovative<br />
therapies, thereby enabling targeted therapy in lung cancer.<br />
“<strong>The</strong> American Lung Association clearly shares our strong<br />
belief in the need to facilitate research into adenocarcinoma,”<br />
said Meyerson. “We greatly appreciate its support and generosity,<br />
and the opportunities this gift creates for us.”<br />
14 <strong>Impact</strong> <strong>Summer</strong> <strong>2005</strong>
Make your next gift online at www.dana-farber.org.<br />
Bette Winik extends her legacy of compassion<br />
Bette Winik dedicated her life, both<br />
personally and professionally, to<br />
helping others. She was particularly<br />
passionate about the plight of children, the<br />
homeless, and the struggles African-<br />
Americans often face. After her diagnosis<br />
with advanced ovarian cancer in 2003,<br />
Winik was treated at Dana-Farber and<br />
became committed to the cause of cancer<br />
prevention and research.<br />
Though she lost her battle with the disease<br />
at age 56, just one year after being<br />
diagnosed, her indomitable spirit lives on<br />
through numerous charitable bequests, including a<br />
$175,000 gift to Dana-Farber. This generous gift will support<br />
research into early detection of ovarian cancer.<br />
“Bette didn’t just throw money at the causes she cared<br />
about,” said Robert Brown, Winik’s friend of 12 years and<br />
executor of her estate. “She became intimately involved<br />
with each and every organization, and<br />
that spoke to her sincerity for these<br />
charities and their good works.”<br />
Winik was born in Harrison, N.Y.,<br />
and lived most of her adult life in<br />
Newton, Mass. A practicing attorney,<br />
she often represented children entangled<br />
in domestic relations disputes.<br />
Though she never had children of her<br />
own, she developed a deep love for<br />
children through her work.<br />
— Robert Brown Up until her death, Winik volunteered<br />
at Massachusetts Avenue Baptist<br />
Church’s Project Manna food ministry, attended gospel<br />
choir performances, and collected work by local artists<br />
with disabilities.<br />
“Bette was always involved with something,” recalled<br />
Brown. “We had a wonderful friendship, and I miss her<br />
very much.”<br />
“[Bette] became intimately<br />
involved with<br />
each and every organization,<br />
and that spoke<br />
to her sincerity for<br />
these charities and<br />
their good works.”<br />
Left to right: Pictured here in 2001 with<br />
friends Barbara and Sara Brown, Bette<br />
Winik created a legacy of compassion at<br />
Dana-Farber through a bequest gift supporting<br />
ovarian cancer research.<br />
Margie Plotka Levine dedicated her life to empowering others<br />
“Margie was<br />
interested in<br />
establishing her<br />
legacy to<br />
help others.”<br />
— Ralph Levine<br />
Margie Plotka Levine enjoyed<br />
being in touch with the<br />
world and healing her mind,<br />
body, and spirit at her house<br />
on Cape Cod.<br />
In 1989, 43-year-old Margie<br />
Plotka Levine was diagnosed with<br />
the deadliest form of lung cancer—malignant<br />
pleural mesothelioma.<br />
Given months to live, she<br />
fought back by adopting her own<br />
therapeutic program blending traditional<br />
and complementary medicine.<br />
Levine chronicled her recipe for life<br />
in her 2001 book, “Surviving<br />
Cancer” (Broadway Books).<br />
Levine put her affairs in order<br />
and prepared to die, but never lost<br />
hope. She made a provision for a<br />
$100,000 estate gift to support and<br />
name a treatment room in DFCI’s<br />
Leonard P. Zakim Center for<br />
Integrated <strong>The</strong>rapies, where she had<br />
received acupuncture, massage<br />
Established in 1990, the Dana-Farber Society honors the foresight<br />
and generosity of individuals who have included the Institute in<br />
their estate plans. Nearly 150 members and friends gathered at<br />
the Conference Center at Harvard Medical on June 22 for the<br />
Society’s 15th annual recognition dinner, hosted by Co-chairs<br />
Sandy and Dozier Gardner.<br />
At left, left to right: Lee Nadler, MD, senior vice president for<br />
experimental medicine at DFCI, spoke of the enduring partnership<br />
between the <strong>Jimmy</strong> <strong>Fund</strong> and the Boston Red Sox over his longstanding<br />
career with the Institute. Nadler then introduced his<br />
friend and former patient, Institute Trustee Larry Lucchino,<br />
therapy, and nutritional guidance.<br />
She died in March 2004, 14 years<br />
after her diagnosis.<br />
“Margie was interested in establishing<br />
her legacy to help others,”<br />
said Margie’s husband, Ralph Levine,<br />
who started a foundation to fulfill<br />
her dream of donating her book to<br />
cancer patients around the world.<br />
“She zeroed in on this room in the<br />
Zakim Center because it was off the<br />
beaten path and conveyed her goal<br />
of empowering others to heal.”<br />
Under the guidance of Zakim<br />
Center Director Cynthia Medeiros,<br />
LICSW, Levine’s gift will help the<br />
center maintain the frequency of its<br />
current services and provide resources<br />
for introducing new programs.<br />
“In many ways, Margie was like<br />
Lenny Zakim,” said Medeiros of the<br />
center’s namesake. “She, too, was a<br />
tremendous advocate for complementary<br />
therapies who focused her<br />
professional and personal energies on<br />
helping cancer patients gain access to<br />
these services.”<br />
Dana-Farber Society celebrates powerful partnerships<br />
Red Sox president and CEO, congratulating him on the<br />
team’s world championship and saying that together we<br />
will win the World Series against cancer.<br />
At right, left to right: Dana-Farber Society members<br />
Jacquelyn Farber and her husband, Institute Trustee<br />
Darwin Farber, trumpet the group’s success with Society<br />
Co-chairs Sandy Gardner and her husband, Institute<br />
Trustee Dozier Gardner.<br />
For more information about the Dana-Farber Society,<br />
visit www.dana-farber.org/society.<br />
<strong>Impact</strong> <strong>Summer</strong> <strong>2005</strong><br />
15
Calendar<br />
Get involved. Have fun. Beat cancer.<br />
d S E P T E M B E R d<br />
16<br />
From Fenway to the Runway<br />
Join the Red Sox wives at the shops and restaurants<br />
in <strong>The</strong> Heritage On <strong>The</strong> Garden in Boston for<br />
their fourth annual fashion show and luncheon to benefit<br />
DFCI’s Women’s Cancers Program and the Red Sox<br />
Foundation. For more information, call Alicia Gallo at<br />
(617) 632-3611 or visit www.jimmyfund.org/runway.<br />
18<br />
Boston Marathon ® <strong>Jimmy</strong> <strong>Fund</strong> Walk<br />
Be a Hero®. Join more than 6,000 walkers<br />
and travel along the official Boston<br />
Marathon® course in the 17th annual<br />
Walk, presented by Hyundai Motor<br />
America. Participate in the<br />
Hopkinton 26.2-Mile, the Wellesley<br />
13.1-Mile, or the Boston 3-Mile.<br />
Take the first step: register at<br />
www.<strong>Jimmy</strong><strong>Fund</strong>WalkRegistration.org or call the Walk<br />
office at (866) JFW-HERO.<br />
27<br />
Robert A. Kyle Lifetime<br />
Achievement Award<br />
Join us for a very special evening at the<br />
Harvard Club in Boston as the International<br />
Myeloma Foundation presents this annual<br />
award to Dana-Farber’s Kenneth Anderson,<br />
MD. For more information, contact<br />
Sarah Curtis at (617) 632-5091.<br />
<strong>Impact</strong><br />
<strong>Summer</strong> <strong>2005</strong><br />
www.jimmyfund.org and www.dana-farber.org<br />
Dana-Farber Cancer Institute<br />
Division of Development & <strong>The</strong> <strong>Jimmy</strong> <strong>Fund</strong><br />
10 Brookline Place West, 6th Floor<br />
Brookline, MA 02445-7226<br />
Address Service Requested<br />
<strong>The</strong> <strong>2005</strong> Susan F. Smith<br />
Inspiration Award was presented<br />
to Joyce Kulhawik, CBS4-TV arts<br />
and entertainment anchor<br />
and former Dana-<br />
Farber<br />
patient,<br />
during<br />
“Couture for<br />
Hope,” a<br />
fundraising event<br />
hosted by Neiman<br />
Marcus to support DFCI’s<br />
Women’s Cancers Program.<br />
Kulhawik, pictured wearing a<br />
Carolina Herrera gown, is a<br />
three-time cancer survivor.<br />
Thanking those who make a difference.<br />
Non-profit Org.<br />
U.S. Postage<br />
PAID<br />
Dana-Farber<br />
e O C T O B E R e<br />
2<br />
Jeni <strong>Fund</strong> Off-Road Duathlon<br />
Help beat lung cancer by participating in this<br />
third annual athletic event—a sequential 2-mile trail<br />
run, 9-mile mountain bike, and 2-mile trail run—at<br />
Wompatuck State Park in Hingham, Mass. For more<br />
information, contact Alicia Gallo at (617) 632-3611 or<br />
visit www.jenifund.org.<br />
9<br />
B.A.A. Half Marathon ®<br />
Be a part of Dana-Farber’s winning team in the<br />
annual B.A.A. Half Marathon® as it races through Boston’s<br />
Back Bay Fens toward the ultimate finish line: a world<br />
without cancer. For more information, call the Marathon<br />
and Running Programs hotline at (800) 551-7036 or visit<br />
www.jimmyfund.org/halfmarathon.<br />
14 –15<br />
An Evening with<br />
Champions<br />
Don’t miss this world-class figure skating exhibition,<br />
hosted by Eliot House of Harvard<br />
University. This inspirational event has raised more<br />
than $2.2 million for the <strong>Jimmy</strong> <strong>Fund</strong> since 1970.<br />
For more information, call the EWC office at (617)<br />
493-8172 or visit www.aneveningwithchampions.org.<br />
15<br />
Jefferson Starship Galactic<br />
Reunion Concert<br />
Groove to the music performed live by original<br />
members of Jefferson Airplane and Jefferson Starship<br />
at the Berklee Performance Center in Boston.<br />
VIP tickets include meeting the band, a live CD,<br />
and preferred seating. For more information, visit<br />
www.jimmyfund.org/eve/event/jefferson-starship, or contact<br />
Caitlin Fay at (617) 632-4215.<br />
16<br />
Holliston Walks for Breast Cancer<br />
Take a stroll through scenic Holliston, Mass., as<br />
part of this third annual event to benefit breast cancer<br />
research and patient care at Dana-Farber. For more<br />
information, contact Jayne Jones at (508) 893-9927 or<br />
e-mail tjones3924@aol.com.<br />
21–22<br />
Oldies but Goodies<br />
Musical Review<br />
Help fight cancer while listening to local musicians<br />
performing current hits and classic songs dating back<br />
to the 1940s. This event will be held at the First<br />
Methodist Church in Pittsfield, Mass., and tickets are<br />
$10. For more information, contact Cathy Soldo at<br />
(413) 442-3647.<br />
26<br />
QVC presents FFANY Shoes on Sale<br />
Choose among thousands of designer and brandname<br />
shoes offered at half the suggested retail price.<br />
<strong>The</strong> 12th annual Shoes on Sale® event, presented<br />
by QVC and the Fashion Footwear Association of<br />
New York, benefits breast cancer research and<br />
education at DFCI and other national centers.<br />
For more information, contact Sarah<br />
Curtis at (617) 632-5091.<br />
28– 29<br />
Saks ”Key To <strong>The</strong> Cure”<br />
Join the Friends of Dana-<br />
Farber Cancer Institute and Saks<br />
Fifth Avenue for an Oct. 28<br />
luncheon—catered by Boston’s<br />
top restaurants—to benefit<br />
DFCI’s Women’s Cancers Program<br />
(WCP). As part of its “Key To <strong>The</strong><br />
Cure” initiative, Saks will donate 5 percent of all clothing<br />
sales on Oct. 28 – 29 to the WCP. For more information,<br />
contact the Friends office at (617) 632-3021.<br />
wNOVEMBER/DECEMBERw<br />
November<br />
30<br />
Cheers for Children<br />
Celebrate the holidays with fabulous food and<br />
great auction items at the Hampshire House’s Bull &<br />
Finch Pub in Boston, the inspiration for the hit TV<br />
show “Cheers.” For more information, contact Caitlin<br />
Fay at (617) 632-4215.<br />
November & December<br />
Robert’s Snow for Cancer’s Cure<br />
Support Dana-Farber’s lifesaving mission by<br />
purchasing one-of-a-kind designs from<br />
your favorite children’s book illustrators. Chris<br />
Van Allsburg (“<strong>The</strong> Polar Express”), Tomie<br />
dePaola (“Strega Nona”), Barbara Lehman<br />
(“<strong>The</strong> Red Book”), and others will create original<br />
snowflake-shaped works of art and auction them<br />
off to support sarcoma research at DFCI. For more<br />
information, visit www.robertssnow.com.<br />
November & December<br />
Dan Murphy Christmas Tree Sale<br />
Buy a wreath or Christmas tree as part of this 35-year<br />
holiday tradition to benefit the <strong>Jimmy</strong> <strong>Fund</strong>. Trees cost<br />
$15–40 and can be chosen at the Murphy home, located<br />
at 310 Highland Ave. in Randolph, Mass. For more<br />
information, call Dan Murphy at (781) 963-5675.<br />
December<br />
7<br />
CIBC Miracle Day<br />
Make your individual or institutional stock trades<br />
through CIBC World Markets, a full-service investment<br />
bank, and designate the <strong>Jimmy</strong> <strong>Fund</strong> as your charity of<br />
choice. Dana-Farber will receive all of the day’s commissions<br />
that accrue from these trades. For more information,<br />
contact Priya McCue at (617) 632-4906 or visit<br />
www.jimmyfund.org/CIBC.<br />
For more information on all <strong>Jimmy</strong> <strong>Fund</strong> and Dana-Farber events, go to www.jimmyfund.org or www.dana-farber.org.