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<strong>Impact</strong><br />

SUMMER 2008<br />

dana-farber.org and jimmyfund.org<br />

THANKING THOSE WHO MAKE A DIFFERENCE.<br />

Volume 11 • Issue 3<br />

Cycling in solidarity: PMC riders raise<br />

projected $34 million<br />

3<br />

Terrific<br />

Tournaments<br />

For most people, a bike ride means a challenging<br />

workout and the chance to have a little fun. For the<br />

more than 5,500 riders in the 2008 Pan-Massachusetts<br />

Challenge (PMC), it entailed much more: the opportunity<br />

to change the future for cancer patients by raising critical<br />

funds for groundbreaking research and innovative cancer care<br />

programs at Dana-Farber Cancer Institute.<br />

Buoyed by the PMC’s presenting co-sponsors, the Red<br />

Sox Foundation and Overstock.com, along with 200 in-kind<br />

sponsors and more than 2,600 volunteers who manned food<br />

and water stations among other tasks, riders covered up to 190<br />

miles Aug. 2 and 3. <strong>The</strong>y rode despite the challenges of the heat<br />

and occasional summer storms of a New England August and<br />

the demanding hills peppering the route. <strong>The</strong>ir smiling faces<br />

reflected triumph and accomplishment as they crossed the finish<br />

continued on page 7<br />

5<br />

Flavorful<br />

Festival<br />

7<br />

Wheel<br />

Winners<br />

13<br />

Sox<br />

Support<br />

15<br />

Proud<br />

Patrons<br />

Ready to ride: More than 5,500 cyclists from 36 states and eight countries participated in the 29th annual Pan-Massachusetts Challenge.<br />

Everyone wins during Stop & Shop Triple Winner promotion<br />

From April through July, store customers across the Northeast stepped up<br />

to participate in the Stop & Shop Supermarket Company’s Triple Winner<br />

Game, a scratch ticket promotion benefiting Dana-Farber’s fight against<br />

pediatric brain tumors and the late effects of treatment. Purchased for $1 each, the<br />

tickets offered participants the potential to instantly win free items, coupons, gift<br />

cards, or cash prizes of up to $10,000. Game players could also double their luck<br />

with the program’s 2nd Chance Sweepstakes, in which previously scratched tickets<br />

were entered into a drawing for unclaimed prizes of more than $500.<br />

This combination of philanthropy and fun once again proved irresistible to<br />

customers, who contributed more than $2.5 million toward both the Stop & Shop<br />

Family Pediatric Brain Tumor Clinic and Stop & Shop Pediatric Neuro-Oncology<br />

“By supporting cancer care and research initiatives at<br />

Dana-Farber, we all look forward to bringing about the<br />

day when this terrible disease is a distant memory.”<br />

— Institute Trustee Jose Alvarez<br />

Outcomes Clinic. Since 1991, the Triple Winner Game, which is co-sponsored<br />

by the Boston Red Sox, has cumulatively raised more than $40 million for these<br />

world-renowned clinics.<br />

“Stop & Shop and its generous customers, dedicated associates, suppliers, and<br />

distributors have a long and proud tradition of philanthropy and service to the<br />

community that I am thrilled to continue,” said Institute Trustee Jose Alvarez, an<br />

executive at Ahold, Stop & Shop’s parent company. “By supporting cancer care<br />

and research initiatives at Dana-Farber, we all look forward to bringing about the<br />

day when this terrible disease is a distant memory.”<br />

Advancing treatments while improving cure rates<br />

Founded in 1997, the Stop & Shop Family Pediatric Brain Tumor Clinic is part<br />

of the largest pediatric brain and spinal cord tumor program in New England<br />

and is recognized as one of the most comprehensive pediatric brain cancer centers<br />

in the world. This program brings together multidisciplinary specialists from<br />

Dana-Farber and Children’s Hospital Boston to deliver the most effective treatments<br />

continued on page 9


Giving is easy when you visit us online at dana-farber.org/give.<br />

Dear Friends,<br />

This May, Dana-Farber Cancer Institute celebrated<br />

the 60th anniversary of the <strong>Jimmy</strong> <strong>Fund</strong> and<br />

the enormous impact that this community of<br />

supporters has had on the fight against cancer<br />

over the years. In 1948, pediatric cancers were<br />

almost universally fatal. Today the survival rate<br />

is 75 percent, and as high as 90 percent for some<br />

forms of the disease. Adult survival rates also continue to rise thanks to<br />

breakthroughs such as the recently developed “smart” drug, Gleevec®. Gifts<br />

to the <strong>Jimmy</strong> <strong>Fund</strong> have helped to make these positive statistics possible.<br />

It is this consistent stream of support that propels new generations of<br />

bold research endeavors, such as the creation of a cancer-signaling roadmap,<br />

as well as innovative patient care initiatives like the Sibling Program, both<br />

of which carry the potential to improve quality of life for our patients and<br />

their families.<br />

In this issue of <strong>Impact</strong>, we highlight these advances and the generosity<br />

of the event participants, corporate sponsors, volunteers, and individual<br />

friends who make them possible.<br />

One such example is the Pan-Massachusetts Challenge, which once<br />

again displayed its enormous commitment to accelerating the Institute’s<br />

mission as more than 5,500 cyclists, 2,600 volunteers, and numerous<br />

sponsor organizations worked together to help the bike-a-thon raise an<br />

anticipated $34 million for the <strong>Jimmy</strong> <strong>Fund</strong>. We thank each and every one<br />

of them for their incredible energy and dedication to this wonderful event!<br />

Many of you showed your support in the supermarket aisles at<br />

Stop & Shop this spring and summer by participating in the Triple Winner<br />

Game program. This long-running promotion benefits Dana-Farber’s Stop<br />

& Shop Family Pediatric Brain Tumor Clinic and the Stop & Shop Family<br />

Pediatric Neuro-Oncology Outcomes Clinic. With more than two million<br />

customers raising $2.5 million, Stop & Shop Supermarket Company<br />

exemplifies the impact that a corporate sponsor can have in the fight<br />

against cancer.<br />

As a volunteer organization, the Friends of Dana-Farber Cancer Institute<br />

has made an incredible commitment to our lifesaving mission for more<br />

than 30 years. We are delighted by this year’s signature fundraiser “Surprise<br />

Party,” held May 30, which resulted in over 400 people enjoying an evening<br />

of surprises and raising a wonderful $1 million to fuel groundbreaking<br />

research, clinical trials, and to support community outreach programs at<br />

Dana-Farber.<br />

Demonstrating the value of individual support, Steven and Michele<br />

Kirsch’s terrific $1 million gift not only bolsters the work of Irene Ghobrial,<br />

MD, who is making critical research advancements in Waldenström’s<br />

macroglobulinemia, but also supports our $1 billion goal for Mission<br />

Possible: <strong>The</strong> Dana-Farber Campaign to Conquer Cancer. <strong>The</strong> Kirsches’<br />

generosity highlights the absolute necessity of private philanthropy to<br />

further research in specific disease areas, and we thank them for working to<br />

change the outlook for those suffering from this rare disease.<br />

<strong>The</strong>se are just a few of the numerous ways in which our loyal community<br />

is helping to strengthen our future and build upon our momentum to<br />

conquer cancer. And for that, we thank you all.<br />

Sincerely,<br />

Susan S. Paresky<br />

Senior Vice President for Development<br />

Siblings coping with cancer<br />

aided by foundation grant<br />

When a child is diagnosed with cancer, his or her entire family often<br />

struggles to cope with this new reality. Dana-Farber’s Sibling Program<br />

provides critical support to brothers and sisters of cancer patients<br />

whose daily lives are often heavily affected by their siblings’ diagnosis and<br />

treatment, leaving them prone to depression, anxiety, and school-related problems.<br />

Recognizing the importance of this landmark psychosocial initiative, which<br />

received seed funding through the Friends of Dana-Farber Cancer Institute<br />

for several years, the Lawrence J. and Anne Rubenstein Charitable Foundation<br />

recently gave $261,000 to expand and enhance the program.<br />

“This grant will provide additional services, including education, counseling,<br />

and special activities, all of which will help ease the stress these children often<br />

face,” said Foundation Trustee Steven Perlmutter, also a Dana-Farber trustee.<br />

<strong>The</strong> Rubenstein Foundation’s grant will enable siblings of young cancer patients to receive critical<br />

emotional and psychological support as they cope with their brother’s or sister’s diagnosis.<br />

A part of DFCI’s Division of Pediatric Psychosocial Services, the Sibling<br />

Program—which is considered a national model for similar programs across the<br />

country—provides psychosocial support to a sibling from the beginning of his<br />

or her brother’s or sister’s diagnosis, continuing through either survivorship or<br />

bereavement. <strong>The</strong>se services include psychological and emotional assessments, as<br />

well as events and activities in which the children can interact with others facing<br />

similar situations.<br />

Research has shown that the stress levels in siblings of cancer patients is often<br />

equal to that of the ill child, and activities that foster bonding among these<br />

siblings help to reduce stress and other emotional and social issues.<br />

“This grant provides a solid, critical base for the program to expand and reach<br />

even more individuals,” said Deborah Bond Berk, LICSW, coordinator of the<br />

Sibling Program. “<strong>The</strong>se children, whose lives are turned upside down, will be<br />

completely supported through the generosity of the Rubenstein Foundation.”<br />

Added DFCI’s Chief of Staff Stephen E. Sallan, MD, “It’s my pleasure to<br />

express the Institute’s long-term support for our Sibling Program, an initiative that<br />

poignantly represents Dana-Farber’s patient-family centered care mission.”n<br />

Help Dana-Farber make<br />

its mission possible<br />

Be a part of Dana-Farber’s campaign to conquer cancer. Contact<br />

Julia Parrillo, Assistant Vice President, Campaign and Development,<br />

at 617-632-6573 or julia_parrillo@dfci.harvard.edu to learn how.<br />

dana-farber.org/campaign<br />

Golfers primed to notch another hole in one<br />

<strong>Jimmy</strong> <strong>Fund</strong> Golf charged into its 26th year with the same drive that made<br />

last season a landmark year for fundraising. By the end of July, the program’s<br />

dedicated tournament organizers, volunteers, and participants had already<br />

raised $3.1 million toward its more than $7 million goal in support of research<br />

and patient care initiatives at Dana-Farber.<br />

Left to right: Tournament Co-chairs Stuart and Maxine Rosenthal, Matt Langweber, Ellie Svenson, Karen<br />

Langweber, Laraine Levy, and Helene and Mark Lapman celebrate the success of the John R. Svenson Classic.<br />

On June 2, the John R. Svenson Classic, a new addition to <strong>Jimmy</strong> <strong>Fund</strong> Golf<br />

in 2008, advanced DFCI’s crusade against cancer by raising $250,000. Held at the<br />

Belmont Country Club in Belmont, Mass., the tournament honored the memory of<br />

John R. Svenson, a founder of the real estate development company the Abbey Group<br />

and co-owner of the Boston Celtics, who succumbed to cancer in July 2007.<br />

“John was extremely generous and always emphasized the importance of giving<br />

back to others,” said Svenson’s wife, Ellie. “This tournament serves as a means for<br />

us to remember him while passing on his message.”<br />

Golfers also gave their time and energy at the 22nd annual Mark R. Ungerer<br />

Driving for the Cure Memorial Golf Tournament, held July 13 and 14 at <strong>The</strong><br />

International in Bolton, Mass. This year’s tournament, co-chaired by Jim Coghlin<br />

Sr. and Tom Mack and coordinated by Susan Cyr, tallied nearly $530,000, which<br />

is earmarked to support cancer research for adolescent and young adult patients<br />

between the ages of 15 and 40. <strong>The</strong> event also celebrated the lives of the late Mark<br />

R. Ungerer, one of three original organizers of the tournament, and his son, David,<br />

who also passed away from cancer.<br />

“ Running a tournament allows you to get to know your<br />

colleagues and business partners outside of your normal<br />

business practice. It’s also a great team-building experience.<br />

<strong>The</strong> satisfaction you get when you hand over a check to<br />

such a worthwhile organization for such a great cause is<br />

unparalleled. It’s an incredibly rewarding experience.”<br />

— MICHAEL MCKNIGHT<br />

Vice President of Construction, Stop & Shop<br />

Stop & Shop Donovan/Carlson <strong>Jimmy</strong> <strong>Fund</strong> Golf Classic<br />

Launched in 1992<br />

On June 23, golfers took to the fairways to fight leukemia at the Kristin <strong>Fund</strong><br />

Leukemia Foundation Golf Tournament. Held at the Oak Hill Country Club<br />

in Fitchburg, Mass., the tournament raised more than $100,000 in support of<br />

Richard Stone, MD, director of the Adult Acute Leukemia Program at DFCI,<br />

while paying tribute to Kristin Amico Sesselman, who passed away from leukemia<br />

in July 2000.<br />

A day of triumphs<br />

Three tournaments made another tremendous impact in Dana-Farber’s fight<br />

against cancer by collectively raising an astounding $875,000 in one day.<br />

On June 16, the 29th annual <strong>Jimmy</strong> <strong>Fund</strong> Golf Tournament/Jeffrey Vinick<br />

Memorial contributed to the momentum by tallying more than $500,000.<br />

Coordinated by the <strong>Jimmy</strong> <strong>Fund</strong> Council of Western Massachusetts and a<br />

committee of more than 50<br />

key Dana-Farber supporters,<br />

including Institute Trustees<br />

Barbara and James Sadowsky,<br />

the event was played on five<br />

separate courses across Western<br />

Massachusetts and Connecticut.<br />

<strong>The</strong> <strong>Jimmy</strong> <strong>Fund</strong> Players<br />

Tournament, hosted by Institute<br />

Trustees Paul Severino, Mike<br />

Champa, and Jim Dow, carried<br />

the momentum, bringing in<br />

more than $200,000 for DFCI’s<br />

High-Tech Multidisciplinary<br />

Research <strong>Fund</strong>, which<br />

provides scientists with access<br />

to sophisticated technology<br />

that increases the speed and Tom Mack (left) and Jim Coghlin Sr. served as co-chairs at the 22nd<br />

annual Mark R. Ungerer Driving for the Cure Memorial Golf Tournament.<br />

accuracy of their work.<br />

At the Black Rock Country<br />

Club in Hingham, Mass., the <strong>Jimmy</strong> <strong>Fund</strong> Council of Greater Boston’s <strong>Jimmy</strong><br />

<strong>Fund</strong>/UGL-Unicco Golf & Tennis Classic drove it all home by raising more than<br />

$150,000 to further the Institute’s lifesaving mission.<br />

With solid efforts through its season’s midway point, <strong>Jimmy</strong> <strong>Fund</strong> Golf is<br />

poised to score yet another record-breaking year in its storied history.<br />

“Our tournament directors and volunteers and their dedication and<br />

commitment were truly the driving force behind this strong start,” said <strong>Jimmy</strong><br />

<strong>Fund</strong> Golf Director Nancy Rowe. “<strong>The</strong>ir compassion for others and love of the<br />

game is making a difference in the lives of cancer patients everywhere.”n<br />

MAKE BEATING CANCER<br />

YOUR BUSINESS<br />

Start a corporate <strong>Jimmy</strong> <strong>Fund</strong> Golf tournament.<br />

Expand your business network, reward your employees, and make new contacts.<br />

Visit jimmyfundgolf.org or contact Tim Barry at 866-521-GOLF.<br />

<strong>Impact</strong> SUMMER 2008<br />

Volume 11 • Issue 3<br />

This issue covers gifts received and finalized through<br />

the spring and summer of 2008.<br />

<strong>Impact</strong>, a newsletter of Dana-Farber Cancer Institute and the <strong>Jimmy</strong><br />

<strong>Fund</strong>, is published by the Division of Development in collaboration<br />

with the Department of Communications for friends and supporters<br />

of Dana-Farber and the <strong>Jimmy</strong> <strong>Fund</strong>.<br />

President, Dana-Farber Cancer Institute Edward J. Benz Jr., MD<br />

Chief of Staff Stephen E. Sallan, MD<br />

Chief Medical Officer Lawrence Shulman, MD<br />

Chief Scientific Officer Barrett J. Rollins, MD, PhD<br />

Chief Clinical Research Officer Philip W. Kantoff, MD<br />

Chair of Medical Oncology James Griffin, MD<br />

Chair of Pediatric Oncology Stuart H. Orkin, MD<br />

Chair of Radiation Oncology Jay R. Harris, MD<br />

Chair of Executive Committee for Research David M. Livingston, MD<br />

Senior Vice President for Experimental Medicine Lee M. Nadler, MD<br />

Senior Vice President for Patient Care Services, Chief Nurse<br />

Patricia Reid Ponte, RN, DNSc, FAAN<br />

Senior Vice President for Research Beverly R. Ginsburg-Cooper, MBA<br />

Senior Vice President for Development Susan S. Paresky<br />

Chairman of the <strong>Jimmy</strong> <strong>Fund</strong> Michael J. Andrews<br />

Senior Vice President for Communications Steven R. Singer<br />

<strong>Impact</strong> Editor Brian Geer<br />

Assistant Editor Lauren Carr<br />

Contributors Tiffany Amoakohene, Amy Barberie, Jared Berezin,<br />

Courtney Blenheim, Elizabeth Chernack, David Ferreira, Kristin<br />

Lacey, Daniel Morris, Liz Nelson, Robin Orwant, Patrick Rooney,<br />

Diane Schmidt, Sharon Veino, Coral Vogel, Lindsay Wilber<br />

Art Director Alan Caplan<br />

Designer Beth Rossi<br />

Production Coordinator Georgina Morales Hampe<br />

Photographers Lisa Cohen, Phill Davis, Nikki Dedekian, John<br />

Deputy, Steve Gilbert, Channing Johnson, Raffi Kebabjian, Justin<br />

Knight, Zeff Nikolla, Sam Ogden, Jill Person, Philip Porcella, Rose<br />

Raymond, Len Rubenstein, Richard Schultz, Aaron Washington<br />

To request a copy of <strong>Impact</strong> or to be removed from our mailing list,<br />

please contact:<br />

DFCI Development Office<br />

10 Brookline Place West, 6th Floor<br />

Brookline, MA 02445-7226<br />

617-632-3019 or 800-52-JIMMY<br />

or download an issue at dana-farber.org/impact.<br />

Dana-Farber Cancer Institute provides expert, compassionate care<br />

to children and adults and is home to groundbreaking cancer<br />

discoveries. Since its founding in 1948, the <strong>Jimmy</strong> <strong>Fund</strong> has raised<br />

millions of dollars through thousands of community efforts to<br />

advance Dana-Farber’s lifesaving mission.<br />

Runners’ 10K milestone honored<br />

During its annual “10K Team” reception, held June 11 at Dana-Farber Cancer Institute,<br />

the 2008 Dana-Farber Marathon Challenge (DFMC) recognized the efforts of its 100 top<br />

team fundraisers (right) who each ran 26.2 miles in this year’s Boston Marathon ® and<br />

raised $10,000 or more.<br />

To date, this pacesetting group has collected a combined $1.6 million from their April<br />

run—nearly 40 percent of the $4.5 million goal for this year’s entire 550-person DFMC<br />

team. Every dollar raised by team members supports the Claudia Adams Barr Program in<br />

Innovative Basic Cancer Research at DFCI and its researchers’ efforts to unlock the basic<br />

mysteries of cancer.<br />

2 <strong>Impact</strong> SUMMER 2008<br />

<strong>Impact</strong> SUMMER 2008 3


Courageous patient adds<br />

visibility to Head and Neck<br />

Oncology Program<br />

When Robert Malloy was diagnosed with neck cancer in 2006, his<br />

primary care physician referred him to Marshall Posner, MD, director<br />

of Dana-Farber’s Head and Neck Oncology Program. Thanks to<br />

Posner’s expert care, the former vice<br />

president of Institutional Sales for<br />

Merrill Lynch is now enjoying his<br />

retirement cancer-free.<br />

“<strong>The</strong> people at Dana-Farber<br />

made my treatment a more tolerable<br />

experience,” said Malloy. “It’s not<br />

just about the skilled doctors but also<br />

about the personality and treatment<br />

of individuals like my chemotherapy<br />

nurse, who always made me feel like<br />

everything would be OK,” said Malloy.<br />

In gratitude, Malloy and his wife<br />

recently gave $100,000 to establish the<br />

Rita and Robert Malloy <strong>Fund</strong> for Head<br />

and Neck Cancer Research, which will<br />

<strong>The</strong> Malloys’ gift will fund critical, additional staff for help Posner and his team conduct more<br />

Dana-Farber’s Head and Neck Oncology Program,<br />

clinical trials. This gift also supports<br />

led by Director Marshall Posner, MD.<br />

Mission Possible: <strong>The</strong> Dana-Farber<br />

Campaign to Conquer Cancer.<br />

A laryngectomy and chemoradiotherapy, the common method of neck cancer<br />

treatment for Malloy’s cancer, has only a 15 percent cure rate. However, DFCIdeveloped<br />

treatments have increased the cure rate to 60 to 70 percent. Malloy,<br />

who was treated for very advanced neck cancer, was the first person at Dana-<br />

Farber to participate in an experimental clinical trial conducted by Posner,<br />

which included a four-drug regimen of targeted therapy and taxotere-cisplatinfluorouracil<br />

(TPF) combined with chemoradiotherapy.<br />

“We are thrilled to find private donor support that allows us to conduct these<br />

trials,” said Posner. “Robert Malloy’s bravery and generosity will enable Dana-<br />

Farber to advance cutting-edge therapy for head and neck cancer patients through<br />

clinical trials and clinical research that pharmaceutical companies generally<br />

consider too risky to fund.” n<br />

Run in any race, of any distance, in any city.<br />

Learn more at <strong>Jimmy</strong>fund.org/race or call 617-632-1970.<br />

Sadowsky family dedicated<br />

to defeating lymphoma<br />

Ronald and Brenna Sadowsky and their family have been touched by cancer<br />

in many ways. Despite their difficult personal experiences with the disease,<br />

they are grateful to have been introduced to Dana-Farber’s first-class care.<br />

In honor of their connection to the Institute and their faith in its lifesaving<br />

mission, the Sadowskys have given $100,000 to support research into<br />

lymphoma, a type of cancer that has affected two family members.<br />

“We give to what we believe in, and we have the utmost confidence in Dana-<br />

Farber,” said Ronald Sadowsky.<br />

Led by Arnold Freedman, MD,<br />

of Hematologic Malignancies, the<br />

Sadowskys’ gift will enable DFCI’s<br />

Lymphoma Program to conduct<br />

clinical research into novel drugs.<br />

“Over the past decade,<br />

there has been tremendous<br />

progress in the understanding of<br />

lymphoma, which has fostered<br />

the development of more specific<br />

treatments going after the<br />

malignant cells, with a goal of<br />

lower toxicity,” said Freedman. “At<br />

the same time, support for basic<br />

research has exceeded funding for<br />

clinical research, making the latter<br />

a critical priority.”<br />

In the next year, the program<br />

will offer several new clinical<br />

trials testing drugs that are<br />

highly specific for subtypes of<br />

lymphoma. Both the Sadowskys<br />

and Freedman hope that these<br />

trials will translate into<br />

lives saved. n<br />

Brenna and Ronald Sadowsky (center) and their sons (from left)<br />

Drew, Jace, and Ross have participated in numerous <strong>Jimmy</strong> <strong>Fund</strong><br />

events, including the annual <strong>Jimmy</strong> <strong>Fund</strong> Golf Tournament/Jeffrey<br />

Vinick Memorial.<br />

Making a splash for Dana-Farber<br />

Mutual <strong>Fund</strong>s Against Cancer scores ace for cancer research<br />

on and off the links<br />

More than 400 golfers enjoyed a day on the links at the 14th annual<br />

Mutual <strong>Fund</strong>s Against Cancer (MFAC) Expect Miracles Golf Classic.<br />

Held June 12 at three different courses in Plymouth, Mass., this annual<br />

tournament raised more than $600,000 for the Center for Applied Cancer Science<br />

(CACS) at Dana-Farber.<br />

MFAC began when founder Frank Strauss’ mother, Sandra, was diagnosed with<br />

leukemia and treated successfully at the Institute. While visiting her, Frank could<br />

not help but notice the compassionate treatment and care DFCI patients received<br />

and was inspired to raise funds.<br />

In response, he organized a friends and family golf outing, in which 48<br />

participants raised $6,000 for Dana-Farber. Since then, the tournament has grown<br />

exponentially, raising more than $2.5 million since its inception and attracting top<br />

financial firms as sponsors, including Interactive Data Corp., State Street Corp.,<br />

JPMorgan Chase & Co., and Citi, to name a few.<br />

“At the time of my mother’s diagnosis, I felt that being in the financial industry<br />

meant that I might be in the right place to bring people together for this cause,”<br />

said Strauss, now MFAC chairman. “<strong>The</strong> industry has really embraced us, helping<br />

raise awareness about the need for funds to fight the war on cancer.”<br />

Aside from its financial success —including maintaining an annual growth rate<br />

in excess of 50 percent—MFAC has enjoyed other notable achievements, such<br />

as being selected to ring the opening bell at the New York Stock Exchange and<br />

being honored as “selected charity of the year” for a second year in a row at the<br />

Institutional Investors’ Mutual <strong>Fund</strong>s Award Gala in 2008.<br />

Driving drug discovery<br />

Over the past year, Mutual <strong>Fund</strong>s Against Cancer has directed its giving to<br />

specifically support CACS. Established in 2004, the center is dedicated to<br />

discovering cancer genes within tumors and translating this information into<br />

new treatments. Researchers focus their studies on six cancers that together cause<br />

approximately 60 percent of the cancer deaths in industrialized nations: brain,<br />

colon, lung, melanoma, myeloma, and pancreatic cancers.<br />

Through the mapping of the human genome, CACS researchers have developed<br />

<strong>Jimmy</strong> <strong>Fund</strong> celebrates “scooper” success<br />

A<br />

record-breaking 8,000 gallons of ice cream were served up this year<br />

at the 26th annual <strong>Jimmy</strong> <strong>Fund</strong> Scooper Bowl® presented by FedEx,<br />

raising a cool $350,000 for the <strong>Jimmy</strong> <strong>Fund</strong>. During the nation’s largest<br />

all-you-can-eat ice cream festival, tens of thousands of scoops were enjoyed by<br />

businesspeople, school groups, and families, who flocked to Boston’s City Hall<br />

Plaza to participate in the three-day event held June 10-12.<br />

<strong>The</strong> fun-filled festivities featured more than 40 flavors of ice cream, frozen<br />

yogurt, sorbet, and gelato from 10 of the nation’s leading vendors. Boston<br />

Mayor Thomas M. Menino, the Boston Red Sox wives, and members of the<br />

Boston Cannons lacrosse team all made special appearances during the event.<br />

Musical entertainment from Michael Bouche, local band Clarias, the Friends<br />

of Broadway, Evan Michael, and the brother and sister rock duo Michael and<br />

Marisa delighted attendees as they enjoyed their frosty treats.<br />

On Wednesday evening, the Scooper Bowl debuted “<strong>The</strong> Metro’s Nighttime<br />

Scoop,” catering to the after-work crowd. Local cover band Heart of Boston<br />

served up fun tunes for the ice cream-loving audience.<br />

“<strong>The</strong> <strong>Jimmy</strong> <strong>Fund</strong> Scooper Bowl is truly an event that everyone can enjoy—<br />

families, adults, and kids,” said <strong>Jimmy</strong> <strong>Fund</strong> Chairman Mike Andrews. “This<br />

year was a success thanks to everyone who came out to enjoy a delicious dessert<br />

for a good cause.” n<br />

Mutual <strong>Fund</strong>s Against Cancer Chairman Frank Strauss (front row, center) stands with MFAC’s board of<br />

directors and the Red Sox 2004 and 2007 World Series Trophies at the Expect Miracles Golf Classic June 12.<br />

a more complete atlas of mutated genes that drive these cancers.<br />

“<strong>The</strong> challenge now is to identify those mutations that are essential for the<br />

maintenance of the tumors,” said CACS Director Ronald DePinho, MD. “Drugs<br />

targeting these events are likely to be more highly effective than previous cancer<br />

therapies, in which only one out of every 20 such drugs would receive FDA<br />

approval. MFAC’s funding has helped us to make the cancer drug discovery<br />

process less costly and more efficient.”<br />

Explained Strauss, “We chose to support the CACS not only because we<br />

wanted to show our supporters tangible results from the money raised, but also<br />

because we were very excited about Dr. DePinho. We are confident that these<br />

funds will allow him and his team to revolutionize cancer treatment.” n<br />

Ketsia Vdrine (left) and Tamara Robert beat the heat with frozen scoops at the 26th annual <strong>Jimmy</strong> <strong>Fund</strong><br />

Scooper Bowl ® .<br />

Hundreds of swimmers donned their caps, goggles, and wetsuits this summer for<br />

the 13th annual Boston Harbor Island Swim to benefit the David B. Perini, Jr. Quality<br />

of Life Clinic at Dana-Farber. Held July 11, the exciting 22-mile relay race began<br />

and finished at Rowe’s Wharf in downtown Boston. <strong>The</strong> following day, a half-mile<br />

recreational Nantasket Beach Swim took place in Hull, Mass., where swimmers of all<br />

ages took to the chilly Atlantic to help raise funds for the Perini Clinic’s dual mission of<br />

caring for survivors of pediatric or adolescent cancers and mitigating the late effects<br />

of treatments. Above: Swimmers dive into the waters of Boston Harbor to raise nearly<br />

$300,000 for Dana-Farber.<br />

A picture can say a thousand words.<br />

Our pictures may save thousands of lives.<br />

Commemorate your fun-filled <strong>Jimmy</strong> <strong>Fund</strong> or Dana-Farber event experience<br />

with photos, now available online. Order high-quality prints and specialty items,<br />

including mousepads, mugs, and more!<br />

Visit jimmyfundpictures.org today.<br />

4 <strong>Impact</strong> SUMMER 2008<br />

<strong>Impact</strong> SUMMER 2008 5


Learn more about the Mission Possible Campaign at dana-farber.org/campaign.<br />

Renowned philanthropist’s newest cause hits close to home<br />

PMC continued from page 1<br />

For more than a decade, Steven Kirsch has given tens of millions of dollars<br />

to support medical research, education, environmental protection, and<br />

community-based charities. Committed to making the greatest possible<br />

impact with his gifts, he has always placed a premium on finding and supporting<br />

underfunded yet worthwhile<br />

projects. In August 2007, he found<br />

just such a cause in Waldenström’s<br />

macroglobulinemia—only this time,<br />

it was personal.<br />

“I had never heard of<br />

Waldenström’s before I was<br />

diagnosed with it,” he said. “I had<br />

to crack open the textbooks and do<br />

some research.”<br />

Kirsch was appalled to learn the<br />

deadly blood cancer receives almost<br />

no attention from government<br />

funding agencies or pharmaceutical<br />

companies because it is relatively<br />

rare. Scarce funding means few<br />

scientists study this “orphan”<br />

disease and, therefore, relatively few<br />

treatment options exist for patients.<br />

Determined to change that,<br />

Kirsch began a nationwide search<br />

for the most promising researchers<br />

in the field. He quickly decided<br />

on the only center in the world<br />

Michele and Steven Kirsch hope their support of Waldenström’s<br />

macroglobulinemia research will produce lifesaving treatments<br />

for patients with this rare disease.<br />

<strong>The</strong> good fight<br />

focused specifically on this disease:<br />

Dana-Farber’s Bing Center for<br />

<strong>The</strong> community of Middleton, Mass., came together to honor one of their own with<br />

Jack Fights Back, an inaugural event to raise funds for neuroblastoma research at<br />

Dana-Farber. Held April 6 at the Danversport Yacht Club in Danvers, Mass., the benefit<br />

was organized by Ron and Kim Supino, whose 9-year-old son Jack has successfully<br />

battled this cancer of the nervous system.<br />

Originally expecting a modest turnout, the Supinos were moved by the mass of neighbors<br />

and friends who attended, as well as local businesses that contributed more than<br />

70 items for the raffle and silent auction. At the end of the day, this swell of support<br />

carried Jack Fights Back to a fundraising total of more than $100,000—four times<br />

more than initial expectations.<br />

According to the family, no one was happier with the outcome than Jack himself<br />

(above), who, at one point during the event, took center stage for an impromptu<br />

performance of Elvis Presley’s “Jailhouse Rock.”<br />

Waldenström’s Macroglobulinemia. Impressed by what he saw, Kirsch and his<br />

wife, Michele, have given Dana-Farber $1 million to support the work of Irene<br />

Ghobrial, MD, in the Bing Center.<br />

In recognition of the Kirsches’ generosity, Ghobrial’s laboratory within the<br />

Bing Center has been named the Michele and Steven Kirsch Laboratory for<br />

Waldenström’s Research.<br />

<strong>The</strong> gift also represents an important contribution to Mission Possible: <strong>The</strong><br />

Dana-Farber Campaign to Conquer Cancer.<br />

A two-pronged attack<br />

When deciding which specific projects to fund, Kirsch was particularly drawn<br />

to Ghobrial’s work. One of the greatest obstacles in combating the disease is the<br />

ability of Waldenström’s macroglobulinemia cells to hide out in a patient’s bone<br />

marrow where they are protected from drugs designed to destroy them. Much of<br />

Ghobrial’s research focuses both on understanding how the cancer cells gain entry<br />

into the bone marrow and identifying drugs to force them out of their hiding<br />

places. Using such drugs, she hopes to first “smoke out” the cancer cells and then<br />

kill them with other treatments.<br />

“It’s a nice one-two combination,” said Kirsch. “<strong>The</strong> approach she’s taking<br />

appears the most promising to me.”<br />

In addition to supporting clinical trials based on this strategy, the Kirsch gift<br />

will fuel studies designed to help researchers better understand the basic biology<br />

of the disease and the causes of its progression. It will also fund projects aimed at<br />

identifying new drug targets and transforming that knowledge into novel therapies<br />

as quickly as possible.<br />

Without the Kirsches’ crucial support, many of these promising endeavors<br />

would never get off the ground.<br />

“<strong>The</strong> government doesn’t usually give much money for Waldenström’s<br />

macroglobulinemia research,” said Ghobrial. “This gift is huge in terms of helping<br />

me push our research forward.” n<br />

Bailey gift zeroes in on genetic<br />

roots of rare blood cancer<br />

When Robert “Bob” Bailey was first<br />

diagnosed with Waldenström’s<br />

macroglobulinemia in 1997, few<br />

treatments existed for this unusual illness. In the<br />

decade that followed, his therapeutic options grew,<br />

thanks in large part to Steven Treon, MD, PhD,<br />

director of the Bing Center for Waldenström’s<br />

Macroglobulinemia at Dana-Farber.<br />

“Dr. Treon has done so much for people with<br />

this disease,” said Bailey’s wife, Laura. “Because<br />

of him, there are now treatments that we never<br />

would have thought possible 10 years ago.”<br />

Hoping to build on that success, the Baileys<br />

have given Dana-Farber $750,000 to fund<br />

Treon’s research into the genetics of the rare<br />

blood cancer.<br />

In previous studies, Treon and his colleagues<br />

identified Waldenström’s patients with a family<br />

history of blood cell abnormalities. This subset<br />

of patients may have inherited genetic risk<br />

Robert “Bob” Bailey’s positive experience as a<br />

Dana-Farber patient inspired him and his wife,<br />

Laura, to support Waldenström’s macroglobulinemia<br />

research under the direction of Steven Treon,<br />

MD, PhD (above).<br />

factors that contribute to the development of the disease. With support from the<br />

Bailey Family <strong>Fund</strong>, Treon plans to study these patients and their families in the<br />

hopes of identifying specific genes underlying the illness—information that might<br />

yield important clues about what causes the cancer and how to treat<br />

it more effectively.<br />

“Research on this rare disease is chronically underfunded,” said Treon.<br />

“Without the generous support of people like the Baileys, important projects of<br />

this kind might never move ahead.”<br />

Research and care are major funding priorities of Mission Possible: <strong>The</strong> Dana-<br />

Farber Campaign to Conquer Cancer, and Bailey’s gift supports this<br />

$1 billion fundraising initiative.<br />

Bob Bailey’s survival 11 years after diagnosis is a testament to the power<br />

of DFCI’s ability to rapidly translate discoveries into new therapies to benefit<br />

patients. Already having lived longer than most people with his disease, he believes<br />

the development of new therapies has been crucial in helping him beat the odds.<br />

With this gift, the Baileys hope Treon will one day produce even better treatments,<br />

improving the odds for all Waldenström’s macroglobulinemia patients.<br />

“Obviously, we’re interested in helping a lot of people with this disease,” said<br />

Bob Bailey. “Dr. Treon is the right person, doing the right research, right now.” n<br />

line to collectively raise an anticipated, record-breaking $34 million.<br />

<strong>The</strong> PMC, founded in 1980 by Executive Director and Institute Trustee Billy<br />

Starr, is the largest athletic fundraising event in the nation. It is so well known<br />

that it now draws people from 36 states and eight countries who want to make a<br />

difference in the lives of cancer patients around the globe.<br />

“We at the PMC relish the role we play at Dana-Farber,” said Starr. “We feel<br />

challenged, but capable, of providing this incredible annual gift and, at the same<br />

time, challenged and flattered to find the room for all who want to participate in<br />

this amazing weekend event.”<br />

Thriving and surviving<br />

Paul Schaye, a devoted extreme-sports athlete and Boston native, has participated<br />

in the PMC for 10 years. His team, “Paul’s Posse,” has raised more than $712,000<br />

over the past two years alone. In October 2006, his reason for riding became more<br />

personal: He was diagnosed with stage IV stomach cancer.<br />

“In the past, I rode to help raise money for cancer research, but I never<br />

imagined I would ride as a possible beneficiary of that research,” he said.<br />

Referring to himself as a “cancer thriver,” Schaye faced his treatment with the<br />

same positive power he put into all of his athletic challenges. After major surgery<br />

in November 2007 and with the assistance of the “smart” drug Gleevec®, Paul<br />

remains disease-free. To celebrate this year, he again made the 190-mile journey<br />

with his Paul’s Posse teammates by his side.<br />

“We at the PMC relish the role we play <br />

at Dana-Farber.”<br />

— Institute Trustee Billy Starr<br />

<strong>The</strong> next generation<br />

<strong>The</strong> PMC has rapidly become an event for participants of all ages. Since 1998, the<br />

PMC Kids Ride Program has offered children between the ages of 3 and 15, as<br />

well as their parents and neighbors, the opportunity to create individual bike-athons,<br />

including a short obstacle course for tykes on tricycles and a 26-mile trek<br />

for teens.<br />

“Through these mini bike-a-thons, we are teaching children the benefits of<br />

being active and helping others,” Starr said. “<strong>The</strong> PMC Kids Ride Program is the<br />

future of the PMC.”<br />

In 2008, 30 kids rides were held and are expected to raise $750,000 toward the<br />

PMC’s impressive $34 million goal. n<br />

Left to right: Paul’s Posse team leader Paul Schaye celebrates being a “cancer thriver” with fellow<br />

teammates George Demetri, MD, director of DFCI’s Center for Sarcoma and Bone Oncology, Demetri’s<br />

daughter, Leah Demetri, and Julie Pokela.<br />

Cycling toward cancer cures<br />

More than 300 bicyclists pedaled along four different routes throughout Western<br />

Massachusetts as part of Katelynn’s Ride. Held June 8, the 8th annual fundraiser, which is<br />

affiliated with the Pan-Massachusetts Challenge bike-a-thon, raised $165,000 to benefit<br />

groundbreaking research and treatment at Dana-Farber Cancer Institute. This year’s success<br />

has helped the program surpass $1 million in cumulative fundraising since its inception.<br />

Katelynn’s Ride began in 2000 to honor 11-year-old Katelynn Battista, a <strong>Jimmy</strong> <strong>Fund</strong><br />

Clinic patient who lost her battle against cancer in 1997. Moved by her story, Steve<br />

Stark, of the United States Postal Service, and radio personalities Dan Williams and Kim<br />

Zachary of Mix 93.1-FM in Springfield, Mass., organized the event in her memory.<br />

Right: With his parents, Domenic and Michele Battista, by his side, Luke Battista kicked<br />

off this year’s festivities by cutting the ribbon at the starting line at Hampshire College in<br />

Amherst, Mass.<br />

One PMC cyclist shows his enthusiasm for fighting cancer while pedaling along one of the bike-a-thon’s<br />

various routes.<br />

Left to right: NECN television anchor R.D. Sahl speaks with PMC Founder and Executive Director and<br />

Institute Trustee Billy Starr during the event’s opening ceremonies, which included a check presentation<br />

from younger riders of the PMC Kids Ride.<br />

6 <strong>Impact</strong> SUMMER 2008<br />

<strong>Impact</strong> SUMMER 2008 7


<strong>Impact</strong> is available online at dana-farber.org/impact.<br />

Evenings unite and inspire<br />

Dana-Farber Evenings provide Institute supporters with a unique opportunity to learn<br />

about groundbreaking research and care initiatives as well as to hear from patients<br />

about their personal experiences with cancer. This year’s Spring Evenings in New York<br />

and Boston provided lively forums for many inspirational discussions.<br />

At the New York Spring Evening, hosted by Institute Trustee Mortimer B. Zuckerman<br />

and held May 8 at the Harvard Club of New York City, Kris Carr, a DFCI patient whose<br />

documentary film “Crazy Sexy Cancer” chronicled her journey of healing and selfdiscovery,<br />

spoke to attendees about the importance of maintaining a strong quality of<br />

life and healthy living after diagnosis. Her physician, George Demetri, MD, director of<br />

DFCI’s Center for Sarcoma and Bone Oncology and the Ludwig Center at Dana-Farber/<br />

Harvard Cancer Center, emphasized DFCI’s total patient care philosophy and how<br />

investigators are developing less toxic, targeted therapies for patients.<br />

Below, (left to right): Zuckerman, Carr, and Demetri visit during the event.<br />

Later in the season, guests turned out for the Boston Spring Evening, held June 12 at<br />

<strong>The</strong> Charles Hotel in Cambridge, Mass. This event, hosted by Institute Trustee Shari<br />

E. Redstone, featured Kelley Tuthill, a television reporter for WCVB-TV/DT Boston<br />

and a breast cancer survivor who was treated at DFCI, as well as Tuthill’s physician<br />

Ann Partridge, MD, MPH, director of DFCI’s Program for Young Women with Breast<br />

Cancer. Tuthill shared how she and her family dealt with the challenging decisions that<br />

accompanied her diagnosis and treatments, while Partridge spoke of the exciting breakthroughs<br />

and trends in breast cancer research happening right now at Dana-Farber.<br />

Below, (left to right): Redstone, Tuthill, and Partridge share in the Boston Evening’s<br />

festivities with DFCI President and CEO Edward J. Benz Jr., MD.<br />

Building support for<br />

ovarian cancer research<br />

Every year, the New England Regional Council of Carpenters (NERCC),<br />

its signatory contractors, and the Carpenters Labor-Management Program<br />

(CLMP) join with the affiliated First Trade Union Bank (FTUB) to sponsor<br />

a day of fun and fundraising at the Pinehills Golf Club in Plymouth, Mass. For<br />

the past 12 years, the group has focused on a specific mission: helping to find cures<br />

for ovarian cancer.<br />

Left to right: Tom Flynn, Harry Dow, Mark Erlich, Mike Butler, and Richard Kronish (far right) help raise<br />

funds which in part support the work of DFCI’s Glenn Dranoff, MD (second from right), through the<br />

Research Foundation for the Treatment of Ovarian Cancer.<br />

“You think of construction work as a very male-dominated industry, and<br />

here we are supporting ovarian cancer,” said Tom Flynn, the political director<br />

for NERCC and executive director for CLMP. “We’ve always been a very<br />

philanthropic group, and this is a wonderful way for us to give back to<br />

the community.”<br />

Recently, the group gave $100,000 through its Research Foundation for the<br />

Treatment of Ovarian Cancer to support Dana-Farber’s Glenn Dranoff, MD, and<br />

his studies into the protein MFG-E8. In animal experiments, Dranoff has shown<br />

he can improve the effectiveness of certain ovarian cancer treatments by blocking<br />

the protein; however, transforming such preclinical results into real therapies can<br />

be challenging.<br />

“<strong>Fund</strong>ing to move discoveries from the laboratory bench to patients is often<br />

scarce,” said Dranoff. “That’s where this gift is going to have a huge impact.”<br />

Expediting the development of new therapies is precisely what former FTUB<br />

Chairman Richard Kronish hopes to accomplish with the gift.<br />

“Not many women survive ovarian cancer, so we really want to see this research<br />

move forward,” he said. “Cures can’t come fast enough.” n<br />

Triple Winner continued from page 1<br />

and ensure the highest possible functionality and quality of life for each child.<br />

With more and more children winning their battles against cancer because<br />

of innovative treatments and novel therapeutics, there is an increased focus on<br />

enhancing every survivor’s quality of life. In response to this growing population—<br />

and in recognition of the unique needs of pediatric brain tumor survivors—DFCI<br />

also used funds generated from the Triple Winner Game to launch the Stop & Shop<br />

Pediatric Neuro-Oncology Outcomes Clinic in 2003. This center provides children<br />

and young adults with comprehensive, multidisciplinary medical care and helps<br />

them cope with the long-term effects of brain tumors and the treatments used to<br />

fight them.<br />

“Stop & Shop’s partnership with Dana-Farber has enabled us to build a premier<br />

program in the research and treatment of pediatric brain tumors,” said Mark Kieran,<br />

MD, PhD, director of Pediatric Medical Neuro-Oncology at DFCI. “Without their<br />

steadfast support, the significant advances we have accomplished in cancer biology,<br />

drug design and delivery, and the care and treatment of children with brain tumors<br />

would not have been possible.” n<br />

<strong>The</strong> Ambrose Monell Foundation<br />

provides critical seed funding<br />

<strong>The</strong> Ambrose Monell Foundation has supported many of the nation’s leading<br />

scientific, cultural, and educational institutions for more than 50 years.<br />

For the sixth year in a row, the foundation, recognizing the excellence<br />

Generous unrestricted support from the Ambrose Monell Foundation provides the Institute with flexible<br />

funding to be directed where it is needed most, including patient care priorities.<br />

Fantasy Day scores home<br />

run for Boston Red Sox fans<br />

Playing baseball at Fenway<br />

Park is an experience most<br />

just dream about, but for<br />

300 <strong>Jimmy</strong> <strong>Fund</strong> and Boston Red<br />

Sox fans, it became a reality at the<br />

17th annual <strong>Jimmy</strong> <strong>Fund</strong> Fantasy<br />

Day at Fenway Park in Boston,<br />

held June 28.<br />

Participants contributed funds<br />

to fight cancer in exchange for<br />

the opportunity to bat, field, and<br />

run the bases of America’s most<br />

beloved ballpark.<br />

Off the field, the Ultimate Fan<br />

Experience, created in partnership<br />

with the Red Sox Team Store,<br />

offered spectators the chance<br />

to participate in tours, panel<br />

discussions with baseball experts,<br />

and several family-friendly<br />

activities, including batting cages,<br />

contests, and face painting.<br />

By the end of the day, the<br />

Event sponsor and DFCI Trustee Ken Levine stands on deck<br />

generosity of these sports<br />

to bat in his 17th Fantasy Day at Fenway Park.<br />

enthusiasts helped to raise more<br />

than $500,000 for the Institute’s lifesaving mission.<br />

For many fans, such as Institute Trustee Ken Levine and his brother, Bob,<br />

Fantasy Day has become a family tradition. <strong>The</strong> Levines have participated for<br />

years in honor of their late brother, Mark, who passed away from leukemia in<br />

1987, as well as their father, George, who lost his battle with multiple myeloma<br />

in 2003.<br />

In 2008, the Levines reaffirmed their commitment to Dana-Farber by<br />

sponsoring the event.<br />

“Fantasy Day is an incredible day,” said Ken Levine. “All of us on the field are<br />

hitting, fielding, and having a blast while fighting for such a great cause.” n<br />

INTRODUCING<br />

DANA-FARBER AND THE JIMMY FUND<br />

E-CARDS<br />

of Dana-Farber’s cancer research and care, has supported the Institute with an<br />

unrestricted grant of $100,000.<br />

“We are extremely grateful for the steadfast support of the Ambrose Monell<br />

Foundation,” said Institute President and CEO Edward J. Benz Jr., MD.<br />

“Unrestricted gifts are the lifeblood of the Institute. <strong>The</strong>se flexible funds allow<br />

us to be nimble and seize important scientific and clinical opportunities as<br />

they arise.”<br />

Benz went on to say that gifts like the foundation’s provide DFCI physicians<br />

and researchers with the resources they need to blaze new trails in discovering and<br />

developing new and safer treatments for patients.<br />

“We are deeply honored to be counted among their distinguished grantees<br />

again this year,” he added. n<br />

Make an executive decision<br />

to fight cancer.<br />

Make a $5 gift to DFCI to send a festive eCard to honor a<br />

family member, friend, or colleague on a special occasion.<br />

Brighten someone’s day while supporting our efforts to<br />

conquer cancer.<br />

join <strong>Jimmy</strong>’s<br />

circle of friends!<br />

<strong>The</strong> Dana-Farber President’s Circle recognizes leaders who<br />

make annual gifts of $1,500 or more.<br />

To learn more, please call Leigh Janczak at 617-582-7537<br />

or e-mail leigh_janczak@dfci.harvard.edu.<br />

To order your eCard, visit jimmyfund.kintera.org/ecards. For more<br />

information, e-mail Mary Bucci at annual_giving@dfci.harvard.edu.<br />

Sign up for an account at MySpace.com or Facebook.com,<br />

the world’s fastest-growing social networking sites, and add<br />

the <strong>Jimmy</strong> <strong>Fund</strong> as your “friend.” You’ll receive updates on<br />

upcoming events and help us spread the word about our<br />

lifesaving mission.<br />

Learn more at<br />

Myspace.com/jimmyfund48 or<br />

Facebook.com.<br />

Get your plate today at:<br />

jimmyfund.org/soxplate<br />

8 <strong>Impact</strong> SUMMER 2008<br />

<strong>Impact</strong> SUMMER 2008 9


Join our MySpace and Facebook communities at Myspace.com/jimmy48 and Facebook.com.<br />

Endowed fund addresses young adults’ psychosocial needs<br />

Though survival rates for pediatric and adult cancer patients have risen<br />

approximately 30 percent over the past two decades, this encouraging trend<br />

does not encompass the 67,000 individuals ages 15 to 40 who are diagnosed<br />

with cancer each year. For this<br />

specific age group, survival rates<br />

remain unchanged, and cancer is<br />

still the number one disease-related<br />

cause of death. To improve this<br />

prognosis, Dana-Farber launched<br />

the Adolescent and Young Adult<br />

(AYA) Oncology Program in 2005.<br />

“We’ve known little about the<br />

biology of cancer in young adults,”<br />

explains Karen Albritton, MD,<br />

program director. “Our program<br />

allows scientists to study how cancer<br />

behaves in these patients, and how<br />

the disease affects them specifically.”<br />

A variety of psychosocial issues,<br />

such as isolation from peers and<br />

the need to juggle the demands<br />

of school or work, appear to<br />

contribute to slow progress in<br />

improving the outcomes for these<br />

individuals. After reading about the<br />

Overseeing the Endowed <strong>Fund</strong> for Adolescent and<br />

Young Adult Psychosocial Oncology, DFCI’s Susan<br />

Block, MD, hopes to improve the quality of life for<br />

cancer patients ages 15 to 40.<br />

AYA program in the case statement<br />

for Mission Possible: <strong>The</strong> Dana-<br />

Farber Campaign to Conquer Cancer,<br />

two anonymous donors have<br />

Funnyman Carell rolls out the red carpet<br />

Hollywood shined its spotlight on Boston when actor Steve Carell teamed up with<br />

Dana-Farber for a special screening of his new movie, “Get Smart.” Held June 19 at the<br />

Citi Performing Arts Center, Wang <strong>The</strong>atre, in association with Warner Bros. Pictures,<br />

the second annual “A Premiere Cause” event raised $447,000 for the Zachary Carson<br />

Brain Tumor <strong>Fund</strong> at DFCI. Created in honor of Zachary “Zach” Carson, who lost his<br />

battle against diffuse pontine glioma in September 2007, the fund supports the research<br />

of Carson’s doctor, Mark Kieran, MD, PhD, director of Pediatric Medical Neuro-Oncology<br />

at Dana-Farber.<br />

At right (left to right): Prior to the film, Zach’s brother, Jacob Carson; father, Paul;<br />

mother, Robera; Charm City Cakes’ Duff Goldman and Mary Alice Yeskey; Carell; Charm<br />

City Cakes’ Geoff Manthorne; and Carell’s, actress Nancy Walls, celebrated the event<br />

with a “Get Smart”–inspired phone booth cake.<br />

stepped in with a combined gift of more than $1 million to create the Endowed<br />

<strong>Fund</strong> for Adolescent and Young Adult Psychosocial Oncology at Dana-Farber.<br />

A holistic approach<br />

Susan Block, MD, chair of the new Department of Psychosocial Oncology and<br />

Palliative Care at DFCI, will oversee the new fund, which will provide emotional<br />

support and education to AYA patients, addressing their concerns about fertility,<br />

lifestyle, sexuality and body image, insurance, exercise, and nutrition. It will<br />

assist patients in developing strategies for talking about cancer at school or in the<br />

workplace, communicating with family and friends, and, for young adults who<br />

are parents, finding ways to help their children understand the illness.<br />

<strong>The</strong> fund will provide resources for clinical programs, such as group therapy<br />

and support groups that connect AYA patients to peers with cancer, as well as<br />

individualized services for those struggling to cope or experiencing mental health<br />

issues. In addition to supporting the patients themselves, the new program will<br />

help parents of AYA patients with their own responses to a son’s or daughter’s<br />

cancer diagnosis, and aid them in finding ways to support their children at a<br />

time when, under normal circumstances, the adolescent or young adult would be<br />

forging an independent life.<br />

Since little is known about effective models of psychosocial care for the AYA<br />

population, the program will link research with clinical services. Building on<br />

the resources of the Institute’s Center for Psycho-oncology and Palliative Care<br />

Research, the impact of the clinical services will be systematically evaluated.<br />

This will allow the program to eliminate approaches that yield few results and to<br />

rapidly incorporate those that appear to improve outcomes.<br />

“<strong>The</strong> donors’ vision and extraordinary gift will help us to develop and<br />

disseminate a specialized program to address the unique challenges facing<br />

adolescents and young adults with cancer,” said Block. n<br />

This Holiday Season, Help Conquer Cancer<br />

Send our Cards, Candles, & Creations<br />

An evening of surprises for<br />

the Friends of Dana-Farber<br />

When the curtains closed on an evening of dinner, dancing, and fun<br />

after Surprise Party at Boston’s Wang <strong>The</strong>atre in Boston May 30,<br />

$1 million had been raised to benefit the Friends of Dana-Farber<br />

Cancer Institute.<br />

<strong>The</strong> evening was hosted by Chairs Nina and David Fialkow and Vice Chairs<br />

Bill Karol, an Institute trustee, his wife, Sinesia, and Audrey and Mark Schuster.<br />

A cocktail hour in the lobby set the mood for the night as guests were treated<br />

to a performance by N’Kenge, famed opera and jazz singer, and a dazzling confetti<br />

shower as the theatre doors opened.<br />

Event Vice-chairs (left to right) Sinesia Karol and Institute Trustee Bill Karol, Chairs Nina and David Fialkow,<br />

and Vice-chairs Audrey and Mark Schuster share in the success of Surprise Party.<br />

Once guests were inside, Bill Karol shared his personal experience with cancer,<br />

and Bob Arnott, MD, described his time spent helping children with cancer as a<br />

field reporter for NBC News. <strong>The</strong> surprises continued when attendees played for<br />

great prizes in “<strong>The</strong> Big Game,” a live game show hosted by actor John O’Hurley<br />

of “Seinfeld” fame and host of “Family Feud.”<br />

<strong>The</strong> theater curtains then opened to reveal a spectacular setting for dinner on<br />

the stage; as they dined, attendees were entertained by a flamenco troupe and<br />

another stellar performance by N’Kenge. Following dinner, guests danced on the<br />

stage that was transformed into an edgy urban disco.<br />

“I am happy that Surprise Party was held to benefit the Friends,” said Nina<br />

Fialkow. “I am very impressed with this group that has grassroots beginnings and<br />

has now become a major supporter of DFCI.”<br />

Making Friends<br />

<strong>The</strong> Friends of Dana-Farber, an all-volunteer organization founded in 1976, raises<br />

funds to benefit patient care, support services, and education at the Institute.<br />

“On behalf of the Friends’ board, Co-president Lauren Frei and I are thrilled<br />

with the success of this event,” said Co-president Diane Flynn. “We are excited<br />

about the financial impact this evening is going to bring to research and care<br />

initiatives at the Institute.”<br />

Jean Canellos, honorary director of the Friends of Dana-Farber, a past Friends<br />

president, and cancer survivor, shared in this excitement. “Surprise Party is<br />

bursting forth with new energy that reflects the growth of the Institute, of the<br />

Friends organization, and the entire Boston and New England communities.”<br />

Since its inception, the Friends of Dana-Farber have raised $20 million for<br />

the Institute. n<br />

GPC Biotech Fellowship<br />

invigorates multiple<br />

myeloma research<br />

GPC Biotech is a biopharmaceutical<br />

company working to find effective<br />

treatments to combat cancer.<br />

Wishing to align itself with institutions<br />

that share similar missions, the company<br />

recently established the GPC Biotech<br />

Fellowship in Multiple Myeloma. This two-year, $150,000 fellowship will<br />

support Dana-Farber’s Diana Cirstea, MD, and her research into this incurable<br />

bone marrow cancer.<br />

<strong>The</strong> fellowship is overseen by Noopur Raje, MD, of the Jerome Lipper Center<br />

for Multiple Myeloma and LeBow Institute for Myeloma <strong>The</strong>rapeutics at DFCI,<br />

and director of Massachusetts General Hospital’s Center for Multiple Myeloma.<br />

“Dana-Farber is renowned for groundbreaking research and plays a vital role<br />

in finding new, effective treatments for patients with multiple myeloma,” said<br />

GPC Biotech’s Senior Vice President of Drug Development and Chief Medical<br />

Officer Martine George, MD. “We are pleased to make this contribution to<br />

support the excellent work of Drs. Cirstea and Raje.”<br />

Although the disease carries a low survival rate, a combination of conventional<br />

and targeted drugs have significantly prolonged and improved the lives of<br />

multiple myeloma patients.<br />

“<strong>The</strong> GPC Biotech Fellowship will facilitate research into the development<br />

of agents that are critical to changing patient outcomes,” explained Raje. One<br />

of the agents being explored is GPC Biotech’s kinase inhibitor RGB-286638, a<br />

novel compound targeting an important pathway relevant to myeloma that is<br />

in development.<br />

“This promising inhibitor has the potential to provide for the design of future<br />

clinical testing that combines this with other inhibitors, creating treatments that<br />

will ultimately make a positive difference for our patients,” added Cirstea. n<br />

<br />

<br />

<br />

<br />

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<br />

<br />

<br />

<br />

<br />

<br />

<br />

<br />

<br />

<br />

<br />

<br />

<br />

<br />

Get involved<br />

with the JIMMY FUND in your area<br />

Join a <strong>Jimmy</strong> <strong>Fund</strong> Council in your community. Plan and<br />

participate in inspirational fundraising events while helping<br />

to spread the word about the Institute’s lifesaving mission.<br />

VIEW AND ORDER FROM OUR SELECTION OF CARDS, CANDLES, ORNAMENTS, AND APPAREL AT<br />

danafarber.org/holiday or call 617-632-5344 for a full brochure.<br />

All proceeds will benefit Dana-Farber’s lifesaving mission.<br />

Berkshire County, Greater Boston, R.I./Southeastern Mass., Western Mass.<br />

For more information, contact Janet Caparoso, Regional Director, the <strong>Jimmy</strong> <strong>Fund</strong><br />

Western New England, at 888-546-6938 or visit jimmyfund.org/jfcouncils<br />

BOSTON_4.6528x8.3611_MAG_KTTC.indd 1<br />

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10 <strong>Impact</strong> SUMMER 2008<br />

<strong>Impact</strong> SUMMER 2008 11


Get involved, have fun, and beat cancer at jimmyfund.org.<br />

Sherwoods honor loved one<br />

with multiple myeloma support<br />

Emily Sherwood intimately understands the devastating toll of cancer, as her<br />

sister, Daryl Layzer, battled multiple myeloma for four years. Layzer had<br />

enrolled in a groundbreaking clinical trial led by Kenneth Anderson, MD,<br />

director of the Jerome Lipper Center for Multiple Myeloma and LeBow Institute<br />

for Myeloma <strong>The</strong>rapeutics at Dana-Farber. At that time, the trial offered the<br />

most promising treatment for<br />

Layzer’s disease.<br />

“From the beginning, Daryl<br />

received such excellent care at<br />

Dana-Farber,” recalled Sherwood.<br />

“Our feeling has always been that<br />

we wanted to give back, particularly<br />

to Dr. Anderson and his staff.”<br />

Sherwood and her husband,<br />

Ned, recently gave $131,000 to<br />

expand the Daryl E. Layzer <strong>Fund</strong>,<br />

which they established in Daryl’s<br />

memory with support from her<br />

mother and husband in 1998.<br />

<strong>The</strong> Sherwoods, both members of<br />

DFCI’s Hematologic Oncology<br />

Visiting Committee, hope that<br />

multiple myeloma patients<br />

continue to experience the same<br />

compassionate care that Daryl<br />

Kenneth Anderson, MD, continues to search for<br />

new agents and drug combinations to treat received, and that their gift propels<br />

multiple myeloma.<br />

Anderson’s efforts to develop<br />

new treatments.<br />

“It is so uplifting to hear the advances Dr. Anderson’s team has made,” added<br />

Sherwood. “We hope there will be a day when they tell us they’ve discovered the cure.”<br />

“<strong>The</strong> past support of Daryl’s family was critical in bringing new myeloma<br />

drugs, such as bortezomib and lenalidomide, from the bench to the bedside,” said<br />

Anderson, also the Kraft Family Professor of Medicine at Harvard Medical School.<br />

“This latest gift enables us to develop new drug combinations and devise strategies<br />

to reduce toxicity and block drug resistance in patients.” n<br />

Gala guests help to eradicate<br />

rare blood cancer<br />

Damon Runyon Cancer Research<br />

Foundation paves way for<br />

cancer-signaling roadmap<br />

<strong>The</strong> Damon Runyon Cancer<br />

Research Foundation has<br />

been a leader in fueling<br />

the cutting-edge work of upand-coming<br />

cancer investigators<br />

for more than 60 years. Now,<br />

the foundation is continuing its<br />

longstanding tradition by giving<br />

$450,000 to Dana-Farber’s<br />

Nathanael Gray, PhD, as part of<br />

its new Damon Runyon-Rachleff<br />

Innovation Award.<br />

Out of 425 applicants, Gray is<br />

one of only three scientists in the<br />

U.S. to receive the honor, which<br />

is supported by veteran Silicon<br />

Valley venture capitalist Andrew<br />

Rachleff and his wife, Debbie.<br />

DFCI’s Nathanael Gray, PhD, is one of three cancer<br />

investigators in the U.S. to receive the Damon<br />

Runyon-Rachleff Innovation Award.<br />

“It is difficult for young researchers to compete for grants from the National<br />

Institutes of Health, which are typically awarded to already proven research,”<br />

said foundation Executive Director Lorraine Egan. “<strong>The</strong>se awards are designed<br />

to encourage early-career investigators to take chances on bold, new ideas in the<br />

hopes of making breakthrough discoveries.”<br />

With his award, Gray seeks to build a cancer-signaling roadmap that will track<br />

the chemical messages sent out by a class of proteins called kinases that, when<br />

mutated, can contribute to cancer growth. He believes that identifying these<br />

abnormal signaling pathways in cancer cells may, one day, lead to the discovery of<br />

novel, targeted patient therapies for many forms of cancer.<br />

“Scientific breakthroughs often come through collaboration outside an<br />

immediate field,” said Gray. “Unique funding opportunities, like the Damon<br />

Runyon-Rachleff Innovation Award, encourage the kind of creative thinking that<br />

leads investigators to these discoveries.” n<br />

You don’t have to be a doctor<br />

to cure cancer.SM<br />

INCLUDE DANA-FARBER CANCER INSTITUTE<br />

AS A BENEFICIARY OF YOUR WILL OR TRUST.<br />

Establish a bequest to benefit Dana-Farber<br />

and support this top-ranked national cancer<br />

center in its lifesaving mission. Make a<br />

positive, lasting impact on the lives of<br />

cancer patients everywhere.<br />

Generosity happens<br />

in the workplace<br />

In the last several years, companies have increasingly offered and encouraged<br />

their employees to contribute to charities through workplace giving programs<br />

in an effort to increase philanthropy and raise awareness about important issues,<br />

such as cancer.<br />

This trend has yielded tremendous results for non-profit organizations across<br />

the globe. In 2008, more than 200 firms in the U.S. gave more than $800,000<br />

through DFCI’s Companies for Cures program. <strong>The</strong>se funds fuel Dana-Farber<br />

physician-scientists as they lead groundbreaking research efforts and offer<br />

innovative therapies and hope to patients around the world.<br />

IBM Corporation, which has given to DFCI through its workplace giving<br />

program since 2000, made it easy<br />

for employees and retirees to give<br />

to non-profits, like the Institute,<br />

via payroll deductions, one-time<br />

gifts, or gifts of stock. <strong>The</strong> company<br />

also provided a flexible method for<br />

employees to give a larger amount by<br />

spreading payments out over time.<br />

“Dana-Farber is consistently<br />

ranked one of the most popular<br />

charities for IBM employees<br />

to support in this region,” said<br />

Cathleen Finn, New England<br />

program manager of IBM<br />

Corporate Citizenship and<br />

Corporate Affairs. “Our employees<br />

feel good knowing that they are<br />

helping an important mission in the<br />

fight against cancer.”<br />

To learn more about DFCI’s<br />

Companies for Cures and how your<br />

company can get involved, contact<br />

Mary Bucci at 617-632-3146 or visit<br />

jimmyfund.org/workplacegiving.n<br />

Burger King honored for its<br />

fight against cancer<br />

Dana-Farber’s Companies for Cures program allows<br />

firms like IBM Corporation and its employees to make<br />

a combined impact on the Institute’s groundbreaking<br />

research and care initiatives.<br />

Rally Against Cancer SM<br />

hits grand slam<br />

More than 400 companies, 100 schools, and thousands of Boston Red<br />

Sox fans across New England collectively contributed more than<br />

$500,000 toward cancer care and research initiatives at Dana-Farber<br />

while taking part in the <strong>Jimmy</strong> <strong>Fund</strong>’s third annual Rally Against Cancer SM .<br />

Rally participants from companies and schools formed teams to compete to<br />

Rally Against Cancer Red Sox spokesplayer Dustin Pedroia (center) congratulates John Hancock Long<br />

Term Care employees (left to right) Martin Sheerin, Rally team captain Charlie Griffin, President<br />

Marianne Harrison, and Laura Wooster.<br />

raise the most money and win a visit<br />

from Boston Red Sox second baseman<br />

and 2008 Rally spokesplayer<br />

Dustin Pedroia. By contributing $5<br />

or more, each team member earned<br />

the right to wear Sox apparel to their<br />

office or classroom on April 8 in<br />

honor of the Red Sox home opener<br />

against the Detroit Tigers.<br />

Essex Elementary School in<br />

Essex, Mass., which raised $37,741,<br />

and John Hancock Long Term Care<br />

in Boston, Mass., which raised<br />

$19,060, were the winning teams<br />

and both enjoyed May 16 visits from<br />

Pedroia, who congratulated them for<br />

their efforts.<br />

“I’ve been to Dana-Farber and<br />

seen firsthand how overwhelming<br />

and life-altering cancer can be for<br />

families and patients,” said Pedroia.<br />

“Rally Against Cancer is an easy and<br />

fun way for everyone to help the<br />

<strong>Jimmy</strong> <strong>Fund</strong>, ultimately giving hope<br />

to the people who are fighting this<br />

awful disease.” n<br />

Red Sox second baseman Dustin Pedroia receives a warm<br />

smile from Essex Elementary school student Ollie Tolo.<br />

<strong>The</strong> Boston Red Sox <strong>Jimmy</strong> <strong>Fund</strong> Award is presented annually to individuals and<br />

organizations who have made longstanding commitments to support the lifesaving<br />

mission of Dana-Farber and the <strong>Jimmy</strong> <strong>Fund</strong>. On July 28, this honor was given to the<br />

Burger King Corporation and its franchises in recognition of the restaurant chain’s<br />

steadfast support of Dana-Farber through the A Chance for Kids promotion card<br />

program, which has raised more than $8 million for pediatric care and research since<br />

its inception in 2000.<br />

Defeat Cancer.<br />

Give at Work.<br />

Hundreds of guests turned out for the second annual Reaching for a Cure Gala,<br />

which supported multiple myeloma research at Dana-Farber. Held May 2 at the<br />

Westin Boston Waterfront in Boston, the event featured an elegant evening of dinner<br />

and dancing, and exciting live and silent auctions that included priceless sports<br />

memorabilia, a day with “Law and Order: SVU” star Mariska Hargitay, Caribbean<br />

vacations, and more. Gala attendees also had the opportunity to pose with the 2004<br />

and 2007 Boston Red Sox World Series trophies.<br />

Support our Lifesaving Mission by:<br />

Reaching for a Cure was founded in 2006 by the friends and family of Paul Stepanian,<br />

a multiple myeloma patient at Dana-Farber who was treated at Dana-Farber and is<br />

now in remission. Above: Stepanian enjoys the gala with his wife and event organizer,<br />

Julie (right), co-organizer Stephanie Farrohi (far left), and her daughter, Alexandra.<br />

To start making your plans today, please contact:<br />

Christopher E. Painter, Director of Gift Planning<br />

Phone: 617-632-3756 or 800-535-5577<br />

E-mail: Christopher_Painter@dfci.harvard.edu<br />

dana-farber.org/bequests<br />

Above: In a special on-field ceremony at Fenway Park in Boston, Red Sox CEO and<br />

President, Institute Trustee, and Mission Possible Campaign Co-chair Larry Lucchino<br />

(right of center) and <strong>Jimmy</strong> <strong>Fund</strong> Director Suzanne Fountain (far left) presented the<br />

award to Burger King franchisees and corporate representatives (left to right) Jim Joy,<br />

Josh Wyman, Jim Froio, Melissa Janikies, Larry Kohler, and John Janikies.<br />

• Setting up a workplace giving program in your place of employment<br />

• Giving to Dana-Farber through your company’s United Way Campaign<br />

• Inviting your company to “match” your gift<br />

Learn more at jimmyfund.org/workplacegiving<br />

or call Mary Bucci at 617-632-3146.<br />

12 <strong>Impact</strong> SUMMER 2008<br />

<strong>Impact</strong> SUMMER 2008 13


Leave a legacy. Visit dana-farber.org/giftplanning to learn how.<br />

“<br />

Samis <strong>Fund</strong> to support “a team<br />

that radiates with passion”<br />

Before I came to Dana-Farber for treatment, I had done extensive research<br />

on radiation oncology for prostate cancer, and the name Anthony D’Amico<br />

kept coming up,” said Mike Samis, a resident of Oklahoma City, Okla. “I<br />

soon found out why. I have never been around people with the kind of focus and<br />

passion that I saw in Dr. D’Amico and his staff. <strong>The</strong>y are absolutely committed to<br />

eradicating prostate cancer.”<br />

Inspired by this dedication,<br />

Samis and his wife contributed<br />

$250,000 to establish the Karen<br />

and Michael Samis Family Prostate<br />

Cancer Research <strong>Fund</strong> under the<br />

direction of Anthony D’Amico,<br />

MD, PhD, who is chief of<br />

Genitourinary Radiation Oncology<br />

at Dana-Farber Cancer Institute and<br />

Brigham and Women’s Hospital.<br />

“<strong>The</strong> gift will be used to<br />

elucidate the relationship between<br />

the use of hormonal therapy to<br />

treat prostate cancer and its effect<br />

Mike and Karen Samis (far right), with daughters Carter and her<br />

fiancée, Fred Fellers (center), and Katharine and her fiancée, on a patient’s overall health,”<br />

Kent Regens, “want to participate in a small way and to push explained D’Amico.<br />

promising prostate cancer research along.”<br />

D’Amico has gained<br />

international attention for his work<br />

in the detection, staging, and treatment of prostate cancer, a disease that will<br />

be diagnosed in 186,000 men in the United States this year and claim the lives<br />

of nearly 29,000. In addition to treating patients, he is also a mentor to young,<br />

talented physician-scientists who work in his clinic. <strong>The</strong> Samis <strong>Fund</strong> will allow<br />

D’Amico’s team to spend more time on innovative, promising studies.<br />

“This very generous gift supports research by building the careers of our young<br />

men and women who are performing these studies,” added D’Amico. He believes<br />

it continues Dana-Farber’s tradition of training and supporting exceptional<br />

individuals who will become the next generation of cancer researchers. n<br />

Music of the heart<br />

Dana-Farber supporters and music lovers alike found their interests in harmony<br />

during “Tezz Yancey’s Rhythmic Journey,” an hour-long, melodic program created<br />

to benefit the Leonard P. Zakim Center for Integrative <strong>The</strong>rapies. Held May 8 at the<br />

Cutler Majestic <strong>The</strong>atre in Boston, the show featured Yancey, an accomplished singer,<br />

dancer, and actor, and his company of performers taking the audience of nearly<br />

200 on a lively journey through different eras of music, from jazz and swing to rock,<br />

disco, and funk.<br />

At right: Following the inspiring performance, the event committee members<br />

celebrated the more than $100,000 raised to benefit the Zakim Center’s mission to<br />

provide Institute patients with therapies—such as massage and acupuncture—that<br />

complement more traditional forms of treatment.<br />

Early detection project<br />

launched by Karp family<br />

and H. H. & M. Metals, Inc.<br />

Cancer-screening tests enable physicians to detect certain cancers in their<br />

early stages, which can dramatically improve survival. Screening tests are<br />

particularly helpful for individuals considered at high risk, such as those with<br />

a family history of cancer.<br />

Recently, the Karp family—Harvey<br />

and Jean Karp, Harvey’s brother,<br />

Michael, and sister-in-law, Charlene<br />

Karp—contributed $250,000 to the<br />

Karp Family/H. H. & M. Metals, Inc.<br />

<strong>Fund</strong> for Cancer Research at Dana-<br />

Farber. <strong>The</strong> Karps’ gift will launch a<br />

pancreatic cancer-screening project led<br />

by Sapna Syngal, MD, MPH, director<br />

of Gastroenterology and the Familial<br />

Gastrointestinal Cancer Program at<br />

Dana-Farber/Brigham and Women’s<br />

Cancer Center.<br />

Sapna Syngal, MD, MPH, will utilize CT scan,<br />

“Cancer is prevalent in so many MRI, and endoscopic ultrasound technology to<br />

families, and my hope is that people screen high-risk individuals for pancreatic cancer.<br />

understand the importance of testing,”<br />

said Jean Karp, a colon cancer survivor with a family history of cancer. “Patient<br />

screening for pancreatic cancer is an area that particularly needs a lot of support.”<br />

In the U.S., pancreatic cancer is the fourth leading cause of cancer-related<br />

deaths in males and the fifth in females. <strong>The</strong> disease’s early stages are often without<br />

symptoms, so patients are typically diagnosed at an advanced stage, which<br />

contributes to high mortality rates. Syngal’s team aims to combat this through<br />

improved detection.<br />

“Our study will help identify many patients with early-stage lesions that may<br />

progress to pancreatic cancer while evaluating detection methods that may be<br />

applicable to many populations,” said Syngal. “Initial support from the Karp family<br />

allowed us to conduct critical pilot work, and their recent gift enables us to fully<br />

launch this important endeavor.” n<br />

SAY “I DO”<br />

Markin gift elevates support for Yawkey Center for Cancer Care<br />

As members of Dana-Farber’s community of supporters in Palm Beach,<br />

Fla., David Markin and his wife, Tracy, knew they wanted to support<br />

Mission Possible: <strong>The</strong> Dana-Farber Campaign to Conquer Cancer. <strong>The</strong>ir<br />

family, like so many others, has been affected by cancer, and the Markins<br />

were impressed by the Institute’s focus on high-level patient care and research.<br />

Compelled to make a gift to DFCI, the Markins have given $500,000 in support<br />

of the new Yawkey Center for Cancer Care, a key funding priority of the<br />

$1 billion comprehensive capital campaign.<br />

Designed around Dana-Farber’s core principles of compassionate, comprehensive<br />

care and cutting-edge clinical research, the 13-story, 275,000-square-foot<br />

Yawkey Center will house 100 exam rooms and 150 infusion chairs to accommodate<br />

the needs of Dana-Farber’s expanding patient population. <strong>The</strong> state-of-the-art<br />

patient care facility is being designed as an environmentally friendly “green”<br />

building and is on schedule to open its doors in 2011.<br />

With their gift, the Markins have chosen to name an elevator bank on one of<br />

the clinical floors where patients will go for exams, infusions, and consultations<br />

with their Institute caregivers.<br />

“We felt this was a great way to make a public show of support for Dana-Farber<br />

in the hope that it would compel others to be excited about giving,” said David<br />

Markin. “We feel that Dana-Farber’s mission deserves others’ support and respect.<br />

“Tracy and I hope that one day cancer will be treated as a curable and<br />

controllable disease,” he further explained. “In the future, when patients are<br />

diagnosed, I hope to see a cure for even the types of cancers that right now have a<br />

low probability for survival.” n<br />

A wise investment:<br />

Malkiel’s CGA advances<br />

breast cancer research<br />

Like all good investors, Julian Malkiel likes to see his dollars put to use. It<br />

was this financial savvy that influenced his recent decision to establish a<br />

$250,000 Charitable Gift Annuity (CGA) at Dana-Farber. With an 8.5<br />

percent return, Malkiel’s CGA offers substantial tax benefits —including an<br />

immediate tax deduction and partial tax-free earnings—which explains why<br />

this is the third CGA he has established at Dana-Farber. Furthermore, his gift<br />

advances breast cancer research at the Institute—a battle close to his heart as his<br />

wife, Doris, passed away from the<br />

disease in 1997.<br />

“I have confidence that Dana-<br />

Farber is the kind of place that could<br />

put my money to good work,” said<br />

Malkiel. “I receive a number of<br />

solicitations from other institutions<br />

where I feel my gift would not go very<br />

far. At Dana-Farber, I know it does.”<br />

Though he now resides in Juno<br />

Beach, Fla., Malkiel and his late wife<br />

spent much of their lives in Stowe, Vt.,<br />

and were familiar with Dana-Farber’s<br />

mission to conquer cancer, often<br />

participating in <strong>Jimmy</strong> <strong>Fund</strong> Golf<br />

tournaments.<br />

“This is a special way for me to<br />

honor my wife and further breast<br />

cancer research by investing in an<br />

Doris and Julian Malkiel’s longtime involvement with<br />

the <strong>Jimmy</strong> <strong>Fund</strong> has compelled Julian to establish three<br />

Charitable Gift Annuities (CGAs) at DFCI.<br />

organization we both admired and<br />

that is also located in New England,”<br />

explained Malkiel. n<br />

Tracy and David Markin hope that their gift to the Yawkey Center for Cancer Care will inspire others to<br />

support the Institute.<br />

Creating a lasting legacy<br />

through charity<br />

Advancements in cancer care and research by Dana-Farber’s physician-scientists are<br />

made possible thanks to the generosity and foresight of the members of the Dana-<br />

Farber Society, which welcomes those who have included the Institute in their estate<br />

plans. <strong>The</strong> longstanding tradition of honoring this loyal group of donors, who have<br />

already provided more than $80 million to DFCI since 1989, continued May 14 with<br />

the 18th annual Dana-Farber Society Recognition Dinner.<br />

Society Co-chairs M. Dozier Gardner, an Institute trustee, and his wife, Sandy (above), and<br />

DFCI President and CEO Edward J. Benz Jr., MD, welcomed 150 guests to <strong>The</strong> Charles<br />

Hotel in Cambridge, Mass., for the event. Attendees had the opportunity to hear remarks<br />

from Chief Scientific Officer Barrett J. Rollins, MD, PhD, who spoke poignantly about the<br />

role of stem cell research in the fight against cancer.<br />

For more information about the Dana-Farber Society and how to include the Institute<br />

in your estate plans, please visit dana-farber.org/society or call 800-535-5577.<br />

Choose among our elegant selection of wedding favors or personalize<br />

your own to inform guests that you have made a gift in their honor to<br />

support the lifesaving mission of Dana-Farber and the <strong>Jimmy</strong> <strong>Fund</strong>.<br />

Invest in cures for cancer.<br />

ESTABLISH A CHARITABLE GIFT ANNUITY (CGA) AT DANA-FARBER. RECEIVE SECURE RETURNS<br />

ON YOUR MONEY WHILE YOU SECURE ADVANCES IN CANCER RESEARCH AND CARE.<br />

View and order your favors online at jimmyfund.org/favors or<br />

contact Mary Bucci at 617-632-6099 or JFFavors@dfci.harvard.edu.<br />

Get started today. Contact: Christopher Painter, Director of Gift Planning<br />

Phone: 800-535-5577 or 617-632-3756<br />

E-mail: christopher_painter@dfci.harvard.edu<br />

14 <strong>Impact</strong> SUMMER 2008<br />

<strong>Impact</strong> SUMMER 2008 15


<strong>Impact</strong><br />

SUMMER 2008<br />

Non-profit Org.<br />

U.S. Postage<br />

PAID<br />

Dana-Farber<br />

Dana-Farber Cancer Institute<br />

Division of Development & <strong>The</strong> <strong>Jimmy</strong> <strong>Fund</strong><br />

10 Brookline Place West, 6th Floor<br />

Brookline, MA 02445-7226<br />

ADDRESS SERVICE REQUESTED<br />

dana-farber.org and jimmyfund.org<br />

THANKING THOSE WHO MAKE A DIFFERENCE.<br />

Actor Steve Carell and his wife, actress Nancy Walls<br />

(right), mug for the camera with Nikki Dedekian<br />

during the second annual “A Premiere Cause” event,<br />

benefiting the Zachary Carson Brain Tumor <strong>Fund</strong> at<br />

Dana-Farber. (See related story on page 10).<br />

OCTOBER<br />

4 <strong>The</strong> World’s Sexiest Wines Dinner 15<br />

QVC Presents FFANY Shoes on Sale®<br />

25<br />

Joshua’s Run<br />

Treat yourself to the “world’s sexiest wines” and dine on delicious<br />

fare while supporting Dana-Farber Cancer Institute. Sponsored<br />

by the Wine Advocate <strong>Fund</strong> for Philanthropy, this fabulous event<br />

will be held at the residence of the Ambassador of France in<br />

Washington, D.C., and will be hosted by world-famous wine<br />

critic Robert Parker. For more information, contact Kimberly<br />

Chisholm at 617-632-5091 or visit wineadvocatefund.org.<br />

10,11<br />

12<br />

12<br />

An Evening with Champions<br />

Watch Olympic and world figure<br />

skating champions take to the ice<br />

with Harvard University skaters in an<br />

exhibition to benefit the <strong>Jimmy</strong> <strong>Fund</strong>.<br />

For more information on this 39th<br />

annual event, contact Harvard’s Eliot<br />

House at 617-493-8172 or<br />

ewc@hcs.harvard.edu.<br />

B.A.A. Half Marathon<br />

Race through Boston and Brookline’s<br />

Emerald Necklace park system on your<br />

way to the ultimate finish line: a world<br />

without cancer. Proceeds from this<br />

13.1-mile race support research and<br />

care at Dana-Farber. For more information, contact Mary Ann<br />

McChesney at 617-632-6915 or dfrunners@dfci.harvard.edu.<br />

Bank of America Chicago Marathon®<br />

Run Chicago to raise critical funds for Dana-Farber’s cancer<br />

research and care initiatives. For more information, contact Mary<br />

Ann McChesney at 617-632-6915 or dfrunners@dfci.harvard.edu.<br />

Shop thousands of designer and brand-name shoes at half the<br />

suggested retail price during the 15th annual Shoes on Sale.<br />

Presented by QVC and the Fashion Footwear Association of New<br />

York (FFANY), this event raises funds for breast cancer research<br />

at Dana-Farber and other national cancer centers. For more<br />

information, contact Kimberly Chisholm at 617-632-5091 or<br />

kimberly_chisholm@dfci.harvard.edu.<br />

16-19<br />

19<br />

Saks Fifth Avenue “Key To <strong>The</strong> Cure”<br />

Join the Friends of Dana-Farber and shop at Saks Fifth<br />

Avenue during its Key To <strong>The</strong> Cure shopping<br />

weekend. From Oct. 16 –19, Saks Fifth<br />

Avenue will contribute<br />

2 percent of all clothing sales<br />

to the Women’s Cancers<br />

Program at DFCI. For more<br />

information, contact Sarah<br />

Duggan at 617-632-3021 or<br />

sarah_duggan@dfci.harvard.edu.<br />

<strong>The</strong> Walk Against Breast Cancer<br />

Lace up your sneakers for the<br />

sixth annual walk through scenic<br />

Holliston, Mass., benefiting<br />

breast cancer research and<br />

patient care at Dana-Farber.<br />

For more information, e-mail<br />

hollistonwalksforbreastcancer@<br />

comcast.net or visit<br />

hollistonwalks.org.<br />

Jog along the gorgeous cliffs of Scituate, Mass., while<br />

helping to fight pediatric cancers at Dana-Farber. <strong>The</strong> 12th<br />

annual Joshua’s Run features a 2-mile Fun Run/Walk and<br />

4-mile Road Race for adults, a Kids Fun Run, and the first annual<br />

Andrea’s Après Art Auction. For more information, contact Sarah<br />

Neukom at 617-632-5008 or visit joshuasrun.com.<br />

2<br />

NOVEMBER<br />

ING New York City Marathon®<br />

Dash through New York City in the world’s largest<br />

marathon while supporting the Institute’s mission to<br />

conquer cancer. For more information, contact Mary Ann<br />

McChesney at 617-632-6915 or dfrunners@dfci.harvard.edu.<br />

DECEMBER<br />

Dan Murphy’s Tree/Wreath Sales<br />

Participate in this 40-year-old holiday<br />

tradition and support the <strong>Jimmy</strong> <strong>Fund</strong><br />

by purchasing your wreath or Christmas<br />

tree from the Murphy home, located at<br />

310 Highland Ave. in Randolph, Mass.<br />

Wreaths start at $6 and trees cost<br />

$20 – $50. For more information, call<br />

Dan Murphy at 781-963-5675 or visit<br />

jimmyfund.org/trees<br />

For more information on all <strong>Jimmy</strong> <strong>Fund</strong> and Dana-Farber events, go to jimmyfund.org or dana-farber.org.

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