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Bridging the Gap - International Society Of Sports Nutrition

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• HCY is and intermediate in methionine metabolism<br />

(methylation cycle)<br />

• Increase levels of methionine, increase HCY<br />

• Elevated HCY is systemically proinflammatory and is<br />

associated with increased incidence of:<br />

• Total and CV mortality<br />

• Stroke<br />

• Dementias and Alzheimer's<br />

• Bone fractures<br />

• Preeclampsia<br />

• Neural tube defects<br />

• Reduced mobility and muscle mass in elderly<br />

Verhoef P, de Groot LC<br />

Semin Vasc Med. 2005<br />

Selhub J. Food Nutr Bull<br />

2008

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