Bridging the Gap - International Society Of Sports Nutrition

More documents

Recommendations

Info

• That proteolytic effect (of acidity)has been attributed to two acidosis-induced disturbances in skeletal muscle cells: • stimulation of an ATP- and ubiquitin-dependent proteolytic pathway • enhancement of the oxidation of proteolytically released branched chain amino acids (valine, leucine, and isoleucine), preventing their reuptake for protein synthesis. • Trial– • 60-120 meq KHCO3 (not NaHCO3) • 18 days UNi excretion decreased 14.4gms ▪ Equivalent to 0.43kg of LBM Frassetto L, J Clin Endocrinol Metab. 1997 Lemann J, Kidney Int. 1989
• Inhibition of SNAT2 by metabolic acidosis reducing muscle protein synthesis and increasing proteolysis • SNAT2L-Glutamine (L-Gln) transporter, which controls protein synthesis via amino acid– dependent insulinsignaling through mammalian target of rapamycin (mTOR). • Could be through depletion of Gln Evans, K et al. J Am Soc Neph 2008
Page 1 and 2: Presented by: Jan DeBenedetto Vitaq
Page 3 and 4: • In USA exceeds $3.5 billion ann
Page 5 and 6: • Posits that the spectrum of fun
Page 7 and 8: • ~700 protein products for sale
Page 9 and 10: • Potential allergen issues • C
Page 11 and 12: • Increased levels of proinflamma
Page 13: • Two major SNPs are associated w
Page 16 and 17: • Protein is the leading generato
Page 18 and 19: • Acid (Aging/Catabolic) • Musc
Page 20 and 21: • Stimulates muscle protein degra
Page 24 and 25: Adeva MM
Page 26 and 27: • Select minerals and organic ani
Page 28 and 29: • >1000 mg; figs, molasses • >5
Page 30 and 31: • >100 mg / serving • Pumpkin s
Page 32 and 33: • Caffeine is the most widely use
Page 34: • Significantly blocks adenosine
Page 37 and 38: • Caffeine lowers the threshold f
Page 39 and 40: • 358 sports supplements on bodyb
Page 41 and 42: • Chronic consumption of caffeine
Page 43 and 44: • SOD scavengers • Extramel®
Page 45 and 46: • NSAIDs • Folate • Iron •
Page 47 and 48: • Leads to inflammation, pain, mu
Page 49 and 50: • Multivitamin (above RDA) and mi

Bridging the Gap - International Society Of Sports Nutrition

Create successful ePaper yourself

Delete template?

Save as template?