Drug Coated Balloon Drug-Coated Balloon ... - summitMD.com

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Distal Washout of Paclitaxel Coating • 120 x 7 mm • Paclitaxel Coated Balloon • ?% of Systemic Concentration • % of Drug Clearance? • % Chronic Tissue Retention? Distal Tissue Effect (Embolization) • Acute Ischemic Events (CLI) • Chronic Tissue Effects • Other Organs Toxicity
Paclitaxel Formulation Types Impact on Biological Performance Coating “A” Crystalline Coating “B” Amorphous Crystalline Amorphous Particles Released +++ ++ Uniform Coating ++ +++ Drug Transfer to Vessel +++ ++ Drug Retention vs. Time +++ + Biological Effectiveness +++ ?
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Drug Coated Balloon Drug-Coated Balloon ... - summitMD.com

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