Drug Coated Balloon Drug-Coated Balloon ... - summitMD.com

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Primary Effectiveness Out<strong>com</strong>es Provisional BMS versus DES “It is possible that in selected cases and due to the scaffolding effect, peripheral p DES may be more effective than PCB…then if we are obliged to migrate into a <strong>com</strong>bined approach (PCB + BMS), PCB use will be restricted to longer lesions and smaller vascular territories” Dake M D et al. Circ Cardiovasc Interv 2011;4:495-504504
Fact #4: Sirolimus Analogues • Rapalogs provide well-established therapeutic benefit • Rapalogs provide high level of safety – DES “drug of choice” • PTX chosen for DEB because tissue transfer/absorption is far simpler • So why we do not use them? 19
Page 1 and 2: Drug-Coated Balloon Technologies I:
Page 3 and 4: Mechanism of Drug Delivery and Rest
Page 5 and 6: PACCOCATH ISR- F/U 5 Years Follow U
Page 7 and 8: Impact of Drug Retention (PK) on Va
Page 9 and 10: Mechanism of Action of DCB: Impact
Page 11 and 12: Paclitaxel Formulation Types Impact
Page 13 and 14: Second Generations Coatings Paclita
Page 15 and 16: Fact #2: PCB May Have Limited Effic
Page 17: Vascular Healing of BMS-PCB Combina
Page 21 and 22: Drug Eluting Balloon Nanoparticle B
Page 23 and 24: Opportunities for Improvement SIROL

Drug Coated Balloon Drug-Coated Balloon ... - summitMD.com

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