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Fructose Intolerance<br />

• Too Much Fructose<br />

– Fructose-1-P Aldolase is rate-limiting<br />

– Depletion of P i<br />

– Reduction in [ATP]<br />

– Increase in glycolysis<br />

– Accumulation of lactate (acid) in blood<br />

• Fructose-1-P Aldolase Deficiency<br />

(Genetic Disease)

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