Hirsutism & Virilization
Hirsutism & Virilization
Hirsutism & Virilization
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• Most testosterone in the blood circulates<br />
bound to albumin (19%) or to sex hormonebinding<br />
globulin (SHBG) (80%).<br />
• Free testosterone<br />
a) In normal women (1%).<br />
b) In hirsute women (2%).<br />
c) In men (2 to 3%).<br />
• Androgenicity depends mainly on the<br />
unbound fraction of testosterone because<br />
this represents the active form of the<br />
hormone.