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Hirsutism & Virilization

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5) Oestrogen levels. Estradiol is usually<br />

normal in PCOS, but estrone levels (which<br />

are rarely measured) are elevated because<br />

of peripheral conversion. Levels are variable<br />

in other causes.<br />

6) Increased production of cortisol:<br />

It is associated with Cushing syndrome.<br />

Diagnosis is made by 24-hour urinary-free<br />

cortisol excretion.

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