Skin Biomarkers as objective measures of stratum corneum barrier
Skin Biomarkers as objective measures of stratum corneum barrier
Skin Biomarkers as objective measures of stratum corneum barrier
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Protocol<br />
• Standard Leg-Controlled-Application Testing (LCAT) protocol 2 w<strong>as</strong> used<br />
in this study with a minimum dryness entrance criteria <strong>of</strong> 2.0 (0-5 scale,<br />
0=no dryness) during winter se<strong>as</strong>on.<br />
• The following products were applied once a day.<br />
– Leave-on lotion containing petrolatum;<br />
– Advanced petrolatum-depositing body w<strong>as</strong>h;<br />
– Regular body w<strong>as</strong>h containing sodium laureth sulfate, sodium lauryl<br />
sulfate and cocamidopropyl betaine.<br />
• A total <strong>of</strong> ten consecutive tape strips were taken for biomarker analysis at<br />
the b<strong>as</strong>eline and at week 1, 2, and 3 <strong>of</strong> product usages, respectively.<br />
• The same panelists returned in the summer and their skin biomarkers<br />
were me<strong>as</strong>ured to understand se<strong>as</strong>onal effect.
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