Trazodone for the treatment of sleep disorders in dementia - UnB
Trazodone for the treatment of sleep disorders in dementia - UnB
Trazodone for the treatment of sleep disorders in dementia - UnB
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Arq Neuropsiquiatr 2011;69(1)<br />
<strong>Trazodone</strong>: <strong>sleep</strong> <strong>disorders</strong> <strong>in</strong> <strong>dementia</strong><br />
Camargos et al.<br />
ACKNOWLEDGMENTS – We thank Pr<strong>of</strong>. Pedro Tauil, MD, PhD, <strong>for</strong><br />
assistance <strong>in</strong> method construction and data analysis.<br />
REFERENCES<br />
1. Vitiello MV, Borson S. Sleep disturbances <strong>in</strong> patients with Alzheimer’s<br />
disease: epidemiology, pathophysiology and <strong>treatment</strong>. CNS Drugs<br />
2001;15:777-796.<br />
2. Hope T, Keene J, Gedl<strong>in</strong>g K, Fairburn CG, Jacoby R. Predictors <strong>of</strong> <strong>in</strong>stitutionalization<br />
<strong>for</strong> people with <strong>dementia</strong> liv<strong>in</strong>g at home with a carer. Int J Geriatr<br />
Psychiatry 1998;13:682-690.<br />
3. McCurry SM, Logsdon RG, Teri L, et al. Characteristics <strong>of</strong> <strong>sleep</strong> disturbance<br />
<strong>in</strong> community-dwell<strong>in</strong>g Alzheimer’s disease patients. J Geriatr Psychiatry<br />
Neurol 1999;12:53-59.<br />
4. Elmstahl S, Stenberg I, Annerstedt L, Ingvad B. Behavioral disturbances and<br />
pharmacological <strong>treatment</strong> <strong>of</strong> patients with <strong>dementia</strong> <strong>in</strong> family caregiv<strong>in</strong>g:<br />
a 2-year follow-up. Int Psychogeriatr 1998;10:239-252.<br />
5. Grace JB, Walker MP, McKeith IG. A comparison <strong>of</strong> <strong>sleep</strong> pr<strong>of</strong>iles <strong>in</strong> patients<br />
with <strong>dementia</strong> with lewy bodies and Alzheimer’s disease. Int J Geriatr Psychiatry<br />
2000;15:1028-1033.<br />
6. Mouret J, Lemo<strong>in</strong>e P, M<strong>in</strong>uit MP, Benkelfat C, Renardet M. Effects <strong>of</strong> trazodone<br />
on <strong>the</strong> <strong>sleep</strong> <strong>of</strong> depressed subjects: a polygraphic study. Psychopharmacology<br />
(Berl) 1988;95(Suppl):S37-S43.<br />
7. Scharf MB, Sachais BA. Sleep laboratory evaluation <strong>of</strong> <strong>the</strong> effects and efficacy<br />
<strong>of</strong> trazodone <strong>in</strong> depressed <strong>in</strong>somniac patients. J Cl<strong>in</strong> Psychiatry 1990;51<br />
(Suppl):S13-S17.<br />
8. van Bemmel AL, Havermans RG, van Diest R. Effects <strong>of</strong> trazodone on EEG<br />
<strong>sleep</strong> and cl<strong>in</strong>ical state <strong>in</strong> major depression. Psychopharmacology (Berl)<br />
1992; 107:569-574.<br />
9. Haffmans PM, Vos MS. The effects <strong>of</strong> trazodone on <strong>sleep</strong> disturbances <strong>in</strong>duced<br />
by br<strong>of</strong>arom<strong>in</strong>e. Eur Psychiatry 1999;14:167-171.<br />
10. Kaynak H, Kaynak D, Gozukirmizi E, Guillem<strong>in</strong>ault C. The effects <strong>of</strong> trazodone<br />
on <strong>sleep</strong> <strong>in</strong> patients treated with stimulant antidepressants. Sleep<br />
Med 2004;5:15-20.<br />
11. Suzuki H, Yamadera H, Nakamura S, Endo S. Effects <strong>of</strong> trazodone and imipram<strong>in</strong>e<br />
on <strong>the</strong> biological rhythm: an analysis <strong>of</strong> <strong>sleep</strong> EEG and body core<br />
temperature. J Nippon Med Sch 2002;69:333-341.<br />
12. APA. Diagnostic and statistical manual <strong>of</strong> mental <strong>disorders</strong>. 4th edition ed.<br />
Wash<strong>in</strong>gton, DC: American Psychiatric Association; 1994.<br />
13. McKhann G, Drachman D, Folste<strong>in</strong> M, Katzman R, Price D, Stadlan EM. Cl<strong>in</strong>ical<br />
diagnosis <strong>of</strong> Alzheimer’s disease: report <strong>of</strong> <strong>the</strong> NINCDS-ADRDA Work<br />
Group under <strong>the</strong> auspices <strong>of</strong> Department <strong>of</strong> Health and Human Services<br />
Task Force on Alzheimer’s Disease. Neurology 1984;34:939-944.<br />
14. Lawton MP, Brody EM. Assessment <strong>of</strong> older people: self-ma<strong>in</strong>ta<strong>in</strong><strong>in</strong>g and <strong>in</strong>strumental<br />
activities <strong>of</strong> daily liv<strong>in</strong>g. Gerontologist 1969;9:179-186.<br />
15. Folste<strong>in</strong> MF, Folste<strong>in</strong> SE, McHugh PR. “M<strong>in</strong>i-mental state”. A practical method<br />
<strong>for</strong> grad<strong>in</strong>g <strong>the</strong> cognitive state <strong>of</strong> patients <strong>for</strong> <strong>the</strong> cl<strong>in</strong>ician. J Psychiatr<br />
Res 1975;12:189-198.<br />
16. Hughes CP, Berg L, Danziger WL, Coben LA, Mart<strong>in</strong> RL. A new cl<strong>in</strong>ical scale<br />
<strong>for</strong> <strong>the</strong> stag<strong>in</strong>g <strong>of</strong> <strong>dementia</strong>. Br J Psychiatry 1982;140:566-572.<br />
17. Cumm<strong>in</strong>gs JL, Mega M, Gray K, et al. The Neuropsychiatric <strong>in</strong>ventory:<br />
comprehensive assessment <strong>of</strong> psychopathology <strong>in</strong> <strong>dementia</strong>. Neurology<br />
1994;44: 2308-2314.<br />
18. Doghramji K. Treatment strategies <strong>for</strong> <strong>sleep</strong> disturbance <strong>in</strong> patients with<br />
depression. J Cl<strong>in</strong> Psychiatry 2003;64 (Suppl 14):S24-S29.<br />
19. Wolkove N, Elkholy O, Baltzan M, Palayew M. Sleep and ag<strong>in</strong>g 2. Management<br />
<strong>of</strong> <strong>sleep</strong> <strong>disorders</strong> <strong>in</strong> older people. CMAJ 8 2007;176:1449-1454.<br />
20. James SP, Mendelson WB. The use <strong>of</strong> trazodone as a hypnotic: a critical review.<br />
J Cl<strong>in</strong> Psychiatry 2004;65:752-755.<br />
21. Stahl SM. Stahl’s essential psychopharmacology: neuroscientific basis and<br />
practical applications. 3rd ed, Fully rev. and expanded. ed. Cambridge ; New<br />
York: Cambridge University Press; 2008.<br />
22. Cantarelli MDG, Marcol<strong>in</strong> MA. Trazodona: farmacologia e <strong>in</strong>terações medicamentosas.<br />
Rev Psiquiatr Cl<strong>in</strong> 2006;33:329-336.<br />
23. Saletu-Zyhlarz GM, Abu-Bakr MH, Anderer P, et al. Insomnia <strong>in</strong> depression:<br />
differences <strong>in</strong> objective and subjective <strong>sleep</strong> and awaken<strong>in</strong>g quality to normal<br />
controls and acute effects <strong>of</strong> trazodone. Prog Neuropsychopharmacol<br />
Biol Psychiatry 2002;26:249-260.<br />
24. Nierenberg AA, Adler LA, Peselow E, Zornberg G, Rosenthal M. <strong>Trazodone</strong><br />
<strong>for</strong> antidepressant-associated <strong>in</strong>somnia. Am J Psychiatry 1994;151:1069-<br />
1072.<br />
25. Lebert F, Stekke W, Hasenbroekx C, Pasquier F. Frontotemporal <strong>dementia</strong>:<br />
a randomised, controlled trial with trazodone. Dement Geriatr Cogn<br />
Disord 2004;17:355-359.<br />
26. Yamadera H, Suzuki H, Nakamura S, Endo S. Effects <strong>of</strong> trazodone on polysomnography,<br />
blood concentration and core body temperature <strong>in</strong> healthy<br />
volunteers. Psychiatry Cl<strong>in</strong> Neurosci 1999;53:189-191.<br />
27. Erman MK. Is it a <strong>sleep</strong><strong>in</strong>g pill? Primary Psychiatry 2000;15:34-36.<br />
28. Montgomery I, Oswald I, Morgan K, Adam K. <strong>Trazodone</strong> enhances <strong>sleep</strong> <strong>in</strong><br />
subjective quality but not <strong>in</strong> objective duration. Br J Cl<strong>in</strong> Pharmacol 1983;16:<br />
139-144.<br />
29. Ware JC, Pittard JT. Increased deep <strong>sleep</strong> after trazodone use: a doublebl<strong>in</strong>d<br />
placebo-controlled study <strong>in</strong> healthy young adults. J Cl<strong>in</strong> Psychiatry<br />
1990;51(Suppl):S18-S22.<br />
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