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Beyond IUI, IVF and ICSI - eshre

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<strong>IVF</strong> pioneer L<strong>and</strong>rum B. Shettles<br />

1970 – 2006 (6th edition)<br />

L<strong>and</strong>rum B. Shettles 1909 ‐ 2003<br />

Problems in previous research:<br />

Conflicting research results. Wilcox (1995):<br />

“For practical purposes, the timing of sexual intercourse in<br />

relation to ovulation has no influence on the sex of the baby”<br />

Unreliable estimation of time of ovulation<br />

However: Modern urinary LH‐based hometests<br />

determine ovulation very accurately<br />

A. Wilcox et al. N. Engl. J. Med. 1995<br />

Diet method: History<br />

• 1935 Herbst finds that sex<br />

ratio of Bonellia viridis is<br />

influenced by potassium.<br />

• 1967‐2007 Research on<br />

rats, sows, cattle:<br />

Sex ratio increases with Na, K intake, decreases<br />

with Ca, Mg.<br />

• 1975‐77 Retrospective diet surveys on mothers<br />

with at least 3 boys <strong>and</strong> on mothers with at least<br />

3 girls confirms this.<br />

Page 104 of 127

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